4AP2B

Crystal structure of the human klhl11-cul3 complex at 2.8a resolution
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
365
structure length
359
Chain Sequence
RIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALVSEPVDYRQGLDDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords KELCH-LIKE PROTEIN 11
publication title Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Cell cycle
total genus 145
structure length 359
sequence length 365
ec nomenclature
pdb deposition date 2012-03-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4ap2B01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4ap2B02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4ap2B03
4EOZB 1LDKA 1U6GA 4JGHD 1LDJA 4A64A 4HXIB 4F52A 4N9F3 4APFB 1LDKB 4P5OA 2WZKA 3DQVC 4AP2B 4WQOD 3RTRA 3DPLC
chains in the Genus database with same CATH superfamily
5F3JA 1LDKA 1LDJA 4F52A 2WAUA 4N9F3 3RRCA 2WZKA 3DQVC 3BQLA 3BQIA 2Y8DA 2PFVA 3CMLA 4APFB 3CPZA 4A64A 4AP2B 4WQOD 4NUUA 2B1EA 2XU0A 3BQKA 1LDKB 4P5OA 3RTRA 4EOZB 4NUVA 1U6GA 4JGHD 4HXIB 4YFSA 3DPLC
chains in the Genus database with same CATH topology
4EOZB 1LDKA 1U6GA 4JGHD 1LDJA 4A64A 4HXIB 4F52A 4N9F3 4APFB 1LDKB 4P5OA 2WZKA 3DQVC 4AP2B 4WQOD 3RTRA 3DPLC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EOZ B;  1LDK A;  1U6G A;  4JGH D;  1LDJ A;  4A64 A;  4HXI B;  4F52 A;  4N9F 3;  4APF B;  1LDK B;  4P5O A;  2WZK A;  3DQV C;  4AP2 B;  4WQO D;  3RTR A;  3DPL C; 
#chains in the Genus database with same CATH topology
 5F3J A;  1LDK A;  1LDJ A;  4F52 A;  2WAU A;  4N9F 3;  3RRC A;  2WZK A;  3DQV C;  3BQL A;  3BQI A;  2Y8D A;  2PFV A;  3CML A;  4APF B;  3CPZ A;  4A64 A;  4AP2 B;  4WQO D;  4NUU A;  2B1E A;  2XU0 A;  3BQK A;  1LDK B;  4P5O A;  3RTR A;  4EOZ B;  4NUV A;  1U6G A;  4JGH D;  4HXI B;  4YFS A;  3DPL C; 
#chains in the Genus database with same CATH homology
 4EOZ B;  1LDK A;  1U6G A;  4JGH D;  1LDJ A;  4A64 A;  4HXI B;  4F52 A;  4N9F 3;  4APF B;  1LDK B;  4P5O A;  2WZK A;  3DQV C;  4AP2 B;  4WQO D;  3RTR A;  3DPL C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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