4APFB

Crystal structure of the human klhl11-cul3 complex at 3.1a resolution
Total Genus 141
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
141
sequence length
355
structure length
341
Chain Sequence
MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPNGLKTMCECMSSYLREQGKALQGLDDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
molecule keywords KELCH-LIKE PROTEIN 11
publication title Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
pubmed doi rcsb
source organism Homo sapiens
total genus 141
structure length 341
sequence length 355
ec nomenclature
pdb deposition date 2012-04-02
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB01
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB02
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4apfB03
2WZKA 1LDJA 4F52A 4HXIB 4WQOD 4N9F3 3RTRA 1LDKB 4A64A 1LDKA 4APFB 4AP2B 3DQVC 4EOZB 4JGHD 4P5OA 3DPLC 1U6GA
chains in the Genus database with same CATH superfamily
2WZKA 2PFVA 3RTRA 2Y8DA 3CPZA 3BQIA 2WAUA 5F3JA 4A64A 4YFSA 4APFB 4NUVA 3DPLC 1U6GA 3BQLA 2B1EA 2XU0A 4N9F3 4EOZB 3RRCA 4HXIB 4P5OA 3BQKA 1LDJA 4F52A 4WQOD 4AP2B 1LDKB 1LDKA 3DQVC 3CMLA 4JGHD 4NUUA
chains in the Genus database with same CATH topology
2WZKA 1LDJA 4F52A 4HXIB 4WQOD 4N9F3 3RTRA 1LDKB 4A64A 1LDKA 4APFB 4AP2B 3DQVC 4EOZB 4JGHD 4P5OA 3DPLC 1U6GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WZK A;  1LDJ A;  4F52 A;  4HXI B;  4WQO D;  4N9F 3;  3RTR A;  1LDK B;  4A64 A;  1LDK A;  4APF B;  4AP2 B;  3DQV C;  4EOZ B;  4JGH D;  4P5O A;  3DPL C;  1U6G A; 
#chains in the Genus database with same CATH topology
 2WZK A;  2PFV A;  3RTR A;  2Y8D A;  3CPZ A;  3BQI A;  2WAU A;  5F3J A;  4A64 A;  4YFS A;  4APF B;  4NUV A;  3DPL C;  1U6G A;  3BQL A;  2B1E A;  2XU0 A;  4N9F 3;  4EOZ B;  3RRC A;  4HXI B;  4P5O A;  3BQK A;  1LDJ A;  4F52 A;  4WQO D;  4AP2 B;  1LDK B;  1LDK A;  3DQV C;  3CML A;  4JGH D;  4NUU A; 
#chains in the Genus database with same CATH homology
 2WZK A;  1LDJ A;  4F52 A;  4HXI B;  4WQO D;  4N9F 3;  3RTR A;  1LDK B;  4A64 A;  1LDK A;  4APF B;  4AP2 B;  3DQV C;  4EOZ B;  4JGH D;  4P5O A;  3DPL C;  1U6G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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