4AVMA

Crystal structure of the n-bar domain of human bridging integrator 2.
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
230
structure length
230
Chain Sequence
KQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELKAIVWNNDLLWEDYEEKLADQAVRTMEIYVAQFSEIKERIAKRGRKLVDYDSARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLERQHSN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the N-Bar Domain of Human Bridging Integrator 2.
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords BRIDGING INTEGRATOR 2
total genus 110
structure length 230
sequence length 230
ec nomenclature
pdb deposition date 2012-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03114 BAR BAR domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4avmA00
3DYTA 3I2WA 3ACOA 4WPEA 4AVMA 3G9GA 2C08A 1Y2OA 2D4CA 3QE6A 3Q84A 5C5BA 3ABHA 3HAIA 2Z0OA 1I4LA 4H8SA 2X3WA 1I49A 2X3XA 1X03A 1URUA 3QNIA 3Q0KA 2YKTA 3LLLA 3M3WA 2Z0VA 3HAJA 1I4DA 2X3VA 2Z0NA 4WPCA 4NSWA 2FICA 2RAJA 2V0OA 2RAIA 3OK8A 4DYLA 3QWEA 3SOGA 1X04A 3SYVA 3HAHA 2RAKA 1I4TA 4FZSA 4I1QA 4DCNC 3CAZA 5C5BB 2Q13A 1WDZA 4ATMA 2EFLA 2EFKA 1ZWWA 3PLTA 4NQIA 2D1LA 2Q12A 4BNEA 2ELBA 4AKVA
chains in the Genus database with same CATH superfamily
4EZWA 1HTYA 5FLEX 2GA9D 3ZEDA 4IWPA 3BVVA 3EJTA 4B9QA 4R5LA 3LVTA 1TQTA 1W9MA 4EZYA 2EWFA 2D1LA 4FZOA 4AZGA 4AVMA 2WYIA 4KIKA 2YI9A 4IM0A 3CZNA 4AZBA 4R5KA 3O3NB 4DYLA 3D2FA 2Z8YA 3DX2A 1QWUA 2ND0A 3QE6A 3ABHA 3FD9A 2GF4A 4AZ5A 3Q0KA 1I4DA 4FZPA 3HAHA 5C5BB 4JNFA 2F7RA 1E9VA 4IWOA 1E2UA 1PS3A 1E1DA 2RT6A 4F00A 3EJQA 4EZNA 3LMFA 1R34A 3T49A 2EFLA 2X5CA 3DYTA 2O0I1 3BUBA 2OW6A 3CV5A 3DX0A 1JQKA 3ER9B 4JN4A 3M3WA 1DKXA 3CKDA 3QWEA 4EZZA 3EJUA 4KIKB 4R5JA 3T46A 1DKZA 1SU7A 3QNJA 2F7QA 3D2EA 3D4YA 4EZRA 2YL6A 2N3KA 4H8SA 1HXKA 4PO2A 4NPHA 4FM3A 4E81A 1DKYA 4H6HA 1GN9A 2Q13A 4HR1A 3PLTA 1GNLA 4JWDA 4EZPA 5FIGA 1OAOA 2C08A 1TQVA 1I4LA 4AZHA 1X03A 3UITA 2GAFD 3LLLA 2X3VA 1TQSA 3DX3A 2MI7A 2ZXQA 3DX1A 1R5EA 1SUFA 3I01A 2F7PA 2YIVX 4I1QA 4IM3A 4DCNC 3KAVA 4ATMA 3BUQA 4IM2A 1TQWA 1R33A 3GI7A 2WINM 3RV0A 2YLAA 4AZCA 4JWCA 3C7NA 4JNEA 3D51A 2RAIA 1X04A 4M0MA 3DPPA 5TKYA 2WYHA 4WPCA 3B51X 3G9GA 1MJGA 3KAWA 2JNSA 3VKHA 2YL5A 3EJPA 1SU6A 3B52X 4AZ6A 2PY6A 1GNTA 4JWEA 2EFKA 4EZQA 2JNKA 3I2WA 3DPQA 4F01A 1Y2OA 4EZTA 4EZUA 4R5GA 1QX1A 1ZYLA 1I49A 3BVXA 4EZSA 2YKTA 4HR1B 4R5IA 4EZOA 2ALWA 4JL9A 3SOGA 3VEBA 3QA8A 4D8JA 2YLLA 3L3PA 3OWGA 4NQIA 3T47A 2D4CA 3Q84A 4HY9A 2X3WA 2OZNB 1QWNA 3B53X 1OA0A 2OBMA 4UDXX 2OW7A 3BUIA 4NSWA 2YIAA 1SU8A 3I39X 4H6IA 3OK8A 1O7DB 3BVWA 3F7WA 4EZVA 2F1AA 1OA1A 1ZWWA 4AKVA 4AZCB 4BNEA 1TQUA 3BUPA 2QFFA 3RPMA 4IW0A 3CZSA 2F7OA 3BVUA 2LM0A 3EJSA 2QXLA 2Z0NA 4HYBA 5E84A 1U00A 3SYVA 2OBLA 2RAKA 3KDRA 4FZSA 2YIBA 3CAZA 4G6QA 2Q12A 3ACOA 3D4ZA 3DDGA 2YI8A 2X3XA 1URUA 3QNIA 1O7DC 3RV1A 3DPOA 3D52A 4JLCA 2ND1A 3O3OB 3DDFA 4WPEA 4EZXA 2KHOA 3BLBA 2YL8A 3EJRA 3ERCC 2FICA 3CVRA 2V0OA 2NCZA 2FYVA 3A98A 3BVTA 2F1BA 1LQ7A 2YL9A 3OHXM 4JWIA 3HAJA 2EX3B 2PMRA 4IWQA 3I04A 4AZ7A 2OO2A 3BUDA 2F18A 1WDZA 1UPXA 4UDYX 3O3MB 3T4AG 2QKWA 5KBPA 3D50A 5C5BA 3L3OM 3HAIA 2Z0OA 3VEAA 2Z0VA 1HWWA 3T48A 2RAJA 1YWMA 3DX4A 2LXYA 3ER8C 1I4TA 4AZIA 4E3CA 2ELBA
chains in the Genus database with same CATH topology
3DYTA 3I2WA 3ACOA 4WPEA 4AVMA 3G9GA 2C08A 1Y2OA 2D4CA 3QE6A 3Q84A 5C5BA 3ABHA 3HAIA 2Z0OA 1I4LA 4H8SA 2X3WA 1I49A 2X3XA 1X03A 1URUA 3QNIA 3Q0KA 2YKTA 3LLLA 3M3WA 2Z0VA 3HAJA 1I4DA 2X3VA 2Z0NA 4WPCA 4NSWA 2FICA 2RAJA 2V0OA 2RAIA 3OK8A 4DYLA 3QWEA 3SOGA 1X04A 3SYVA 3HAHA 2RAKA 1I4TA 4FZSA 4I1QA 4DCNC 3CAZA 5C5BB 2Q13A 1WDZA 4ATMA 2EFLA 2EFKA 1ZWWA 3PLTA 4NQIA 2D1LA 2Q12A 4BNEA 2ELBA 4AKVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DYT A;  3I2W A;  3ACO A;  4WPE A;  4AVM A;  3G9G A;  2C08 A;  1Y2O A;  2D4C A;  3QE6 A;  3Q84 A;  5C5B A;  3ABH A;  3HAI A;  2Z0O A;  1I4L A;  4H8S A;  2X3W A;  1I49 A;  2X3X A;  1X03 A;  1URU A;  3QNI A;  3Q0K A;  2YKT A;  3LLL A;  3M3W A;  2Z0V A;  3HAJ A;  1I4D A;  2X3V A;  2Z0N A;  4WPC A;  4NSW A;  2FIC A;  2RAJ A;  2V0O A;  2RAI A;  3OK8 A;  4DYL A;  3QWE A;  3SOG A;  1X04 A;  3SYV A;  3HAH A;  2RAK A;  1I4T A;  4FZS A;  4I1Q A;  4DCN C;  3CAZ A;  5C5B B;  2Q13 A;  1WDZ A;  4ATM A;  2EFL A;  2EFK A;  1ZWW A;  3PLT A;  4NQI A;  2D1L A;  2Q12 A;  4BNE A;  2ELB A;  4AKV A; 
#chains in the Genus database with same CATH topology
 4EZW A;  1HTY A;  5FLE X;  2GA9 D;  3ZED A;  4IWP A;  3BVV A;  3EJT A;  4B9Q A;  4R5L A;  3LVT A;  1TQT A;  1W9M A;  4EZY A;  2EWF A;  2D1L A;  4FZO A;  4AZG A;  4AVM A;  2WYI A;  4KIK A;  2YI9 A;  4IM0 A;  3CZN A;  4AZB A;  4R5K A;  3O3N B;  4DYL A;  3D2F A;  2Z8Y A;  3DX2 A;  1QWU A;  2ND0 A;  3QE6 A;  3ABH A;  3FD9 A;  2GF4 A;  4AZ5 A;  3Q0K A;  1I4D A;  4FZP A;  3HAH A;  5C5B B;  4JNF A;  2F7R A;  1E9V A;  4IWO A;  1E2U A;  1PS3 A;  1E1D A;  2RT6 A;  4F00 A;  3EJQ A;  4EZN A;  3LMF A;  1R34 A;  3T49 A;  2EFL A;  2X5C A;  3DYT A;  2O0I 1;  3BUB A;  2OW6 A;  3CV5 A;  3DX0 A;  1JQK A;  3ER9 B;  4JN4 A;  3M3W A;  1DKX A;  3CKD A;  3QWE A;  4EZZ A;  3EJU A;  4KIK B;  4R5J A;  3T46 A;  1DKZ A;  1SU7 A;  3QNJ A;  2F7Q A;  3D2E A;  3D4Y A;  4EZR A;  2YL6 A;  2N3K A;  4H8S A;  1HXK A;  4PO2 A;  4NPH A;  4FM3 A;  4E81 A;  1DKY A;  4H6H A;  1GN9 A;  2Q13 A;  4HR1 A;  3PLT A;  1GNL A;  4JWD A;  4EZP A;  5FIG A;  1OAO A;  2C08 A;  1TQV A;  1I4L A;  4AZH A;  1X03 A;  3UIT A;  2GAF D;  3LLL A;  2X3V A;  1TQS A;  3DX3 A;  2MI7 A;  2ZXQ A;  3DX1 A;  1R5E A;  1SUF A;  3I01 A;  2F7P A;  2YIV X;  4I1Q A;  4IM3 A;  4DCN C;  3KAV A;  4ATM A;  3BUQ A;  4IM2 A;  1TQW A;  1R33 A;  3GI7 A;  2WIN M;  3RV0 A;  2YLA A;  4AZC A;  4JWC A;  3C7N A;  4JNE A;  3D51 A;  2RAI A;  1X04 A;  4M0M A;  3DPP A;  5TKY A;  2WYH A;  4WPC A;  3B51 X;  3G9G A;  1MJG A;  3KAW A;  2JNS A;  3VKH A;  2YL5 A;  3EJP A;  1SU6 A;  3B52 X;  4AZ6 A;  2PY6 A;  1GNT A;  4JWE A;  2EFK A;  4EZQ A;  2JNK A;  3I2W A;  3DPQ A;  4F01 A;  1Y2O A;  4EZT A;  4EZU A;  4R5G A;  1QX1 A;  1ZYL A;  1I49 A;  3BVX A;  4EZS A;  2YKT A;  4HR1 B;  4R5I A;  4EZO A;  2ALW A;  4JL9 A;  3SOG A;  3VEB A;  3QA8 A;  4D8J A;  2YLL A;  3L3P A;  3OWG A;  4NQI A;  3T47 A;  2D4C A;  3Q84 A;  4HY9 A;  2X3W A;  2OZN B;  1QWN A;  3B53 X;  1OA0 A;  2OBM A;  4UDX X;  2OW7 A;  3BUI A;  4NSW A;  2YIA A;  1SU8 A;  3I39 X;  4H6I A;  3OK8 A;  1O7D B;  3BVW A;  3F7W A;  4EZV A;  2F1A A;  1OA1 A;  1ZWW A;  4AKV A;  4AZC B;  4BNE A;  1TQU A;  3BUP A;  2QFF A;  3RPM A;  4IW0 A;  3CZS A;  2F7O A;  3BVU A;  2LM0 A;  3EJS A;  2QXL A;  2Z0N A;  4HYB A;  5E84 A;  1U00 A;  3SYV A;  2OBL A;  2RAK A;  3KDR A;  4FZS A;  2YIB A;  3CAZ A;  4G6Q A;  2Q12 A;  3ACO A;  3D4Z A;  3DDG A;  2YI8 A;  2X3X A;  1URU A;  3QNI A;  1O7D C;  3RV1 A;  3DPO A;  3D52 A;  4JLC A;  2ND1 A;  3O3O B;  3DDF A;  4WPE A;  4EZX A;  2KHO A;  3BLB A;  2YL8 A;  3EJR A;  3ERC C;  2FIC A;  3CVR A;  2V0O A;  2NCZ A;  2FYV A;  3A98 A;  3BVT A;  2F1B A;  1LQ7 A;  2YL9 A;  3OHX M;  4JWI A;  3HAJ A;  2EX3 B;  2PMR A;  4IWQ A;  3I04 A;  4AZ7 A;  2OO2 A;  3BUD A;  2F18 A;  1WDZ A;  1UPX A;  4UDY X;  3O3M B;  3T4A G;  2QKW A;  5KBP A;  3D50 A;  5C5B A;  3L3O M;  3HAI A;  2Z0O A;  3VEA A;  2Z0V A;  1HWW A;  3T48 A;  2RAJ A;  1YWM A;  3DX4 A;  2LXY A;  3ER8 C;  1I4T A;  4AZI A;  4E3C A;  2ELB A; 
#chains in the Genus database with same CATH homology
 3DYT A;  3I2W A;  3ACO A;  4WPE A;  4AVM A;  3G9G A;  2C08 A;  1Y2O A;  2D4C A;  3QE6 A;  3Q84 A;  5C5B A;  3ABH A;  3HAI A;  2Z0O A;  1I4L A;  4H8S A;  2X3W A;  1I49 A;  2X3X A;  1X03 A;  1URU A;  3QNI A;  3Q0K A;  2YKT A;  3LLL A;  3M3W A;  2Z0V A;  3HAJ A;  1I4D A;  2X3V A;  2Z0N A;  4WPC A;  4NSW A;  2FIC A;  2RAJ A;  2V0O A;  2RAI A;  3OK8 A;  4DYL A;  3QWE A;  3SOG A;  1X04 A;  3SYV A;  3HAH A;  2RAK A;  1I4T A;  4FZS A;  4I1Q A;  4DCN C;  3CAZ A;  5C5B B;  2Q13 A;  1WDZ A;  4ATM A;  2EFL A;  2EFK A;  1ZWW A;  3PLT A;  4NQI A;  2D1L A;  2Q12 A;  4BNE A;  2ELB A;  4AKV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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