4AYAA

Crystal structure of id2 hlh homodimer at 2.1a resolution
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
59
structure length
59
Chain Sequence
DDPMSLLYNMNDCYSKLKELVPSIPQNKKVSKMEILQHVIDYILDLQIALDSHLKPSFL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Divalent Ion is Crucial in the Structure and Dominant-Negative Function of Id Proteins, a Class of Helix-Loop-Helix Transcription Regulators.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords DNA-BINDING PROTEIN INHIBITOR ID-2
total genus 20
structure length 59
sequence length 59
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 4ayaA00
2YPAB 2YPAA 1UKLC 2LFHA 4ATHA 5I4ZA 4F3LA 4F3LB 1NKPA 1NKPB 1AN4A 3MUJA 2QL2A 2QL2B 4ATIA 1MDYA 1NLWB 1MDYB 4H10B 1NLWA 4H10A 2MH3A 3U5VA 4AYAA 1AM9A 1A0AA 1AN2A 1R05A 5EYOA 2YPBB 4ATKA 5I50A 2YPBA 1HLOA
chains in the Genus database with same CATH superfamily
2YPAB 1ZZAA 2YPAA 1UKLC 2LFHA 4ATHA 5I4ZA 1K1FA 4F3LA 4F3LB 1NKPA 1NKPB 1AN4A 3MUJA 2QL2A 2QL2B 4ATIA 1MDYA 1NLWB 1MDYB 4H10B 1NLWA 4H10A 2MH3A 3U5VA 4AYAA 1AM9A 1A0AA 1AN2A 1R05A 5EYOA 2YPBB 4ATKA 5I50A 2YPBA 1HLOA
chains in the Genus database with same CATH topology
2YPAB 2YPAA 1UKLC 2LFHA 4ATHA 5I4ZA 4F3LA 4F3LB 1NKPA 1NKPB 1AN4A 3MUJA 2QL2A 2QL2B 4ATIA 1MDYA 1NLWB 1MDYB 4H10B 1NLWA 4H10A 2MH3A 3U5VA 4AYAA 1AM9A 1A0AA 1AN2A 1R05A 5EYOA 2YPBB 4ATKA 5I50A 2YPBA 1HLOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YPA B;  2YPA A;  1UKL C;  2LFH A;  4ATH A;  5I4Z A;  4F3L A;  4F3L B;  1NKP A;  1NKP B;  1AN4 A;  3MUJ A;  2QL2 A;  2QL2 B;  4ATI A;  1MDY A;  1NLW B;  1MDY B;  4H10 B;  1NLW A;  4H10 A;  2MH3 A;  3U5V A;  4AYA A;  1AM9 A;  1A0A A;  1AN2 A;  1R05 A;  5EYO A;  2YPB B;  4ATK A;  5I50 A;  2YPB A;  1HLO A; 
#chains in the Genus database with same CATH topology
 2YPA B;  1ZZA A;  2YPA A;  1UKL C;  2LFH A;  4ATH A;  5I4Z A;  1K1F A;  4F3L A;  4F3L B;  1NKP A;  1NKP B;  1AN4 A;  3MUJ A;  2QL2 A;  2QL2 B;  4ATI A;  1MDY A;  1NLW B;  1MDY B;  4H10 B;  1NLW A;  4H10 A;  2MH3 A;  3U5V A;  4AYA A;  1AM9 A;  1A0A A;  1AN2 A;  1R05 A;  5EYO A;  2YPB B;  4ATK A;  5I50 A;  2YPB A;  1HLO A; 
#chains in the Genus database with same CATH homology
 2YPA B;  2YPA A;  1UKL C;  2LFH A;  4ATH A;  5I4Z A;  4F3L A;  4F3L B;  1NKP A;  1NKP B;  1AN4 A;  3MUJ A;  2QL2 A;  2QL2 B;  4ATI A;  1MDY A;  1NLW B;  1MDY B;  4H10 B;  1NLW A;  4H10 A;  2MH3 A;  3U5V A;  4AYA A;  1AM9 A;  1A0A A;  1AN2 A;  1R05 A;  5EYO A;  2YPB B;  4ATK A;  5I50 A;  2YPB A;  1HLO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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