4B5HA

Substate bound inactive mutant of neisseria ap endonuclease in presence of metal ions
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
259
structure length
259
Chain Sequence
MLKIISANVNGIRSAYKKGFYEYIAASGTDIVCVQELKAQEADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGNWNIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVVEYDYAAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Neisseria meningitidis
molecule keywords PUTATIVE EXODEOXYRIBONUCLEASE
total genus 77
structure length 259
sequence length 259
ec nomenclature ec 3.1.11.2: Exodeoxyribonuclease III.
pdb deposition date 2012-08-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4b5hA00
3MTCA 2F1NA 5DFFA 5J3PA 3MPRA 2A42B 3G1KA 3G8VA 3K55A 5J3SA 5A7IA 2VOAA 3G00A 4B5GA 1VYBA 2EI9A 4B5IA 4FPVA 2A41B 3CJCD 4GZ0A 3NGOA 4F1HA 4L1YA 2J63A 1YJHA 3G2DA 1ATND 3I46A 5DV2A 1I9YA 5J8NA 2UYRX 3G0AA 4L20A 3G4TA 1NTFA 4PUQA 3U8UA 2DDRA 4GZ1A 3G91A 2DDSA 1E9NA 3N9VA 4GEWA 3I41A 4F1RA 4QHEA 1DNKA 2JC4A 3G0RA 3W3DB 4LNDA 5DFIA 4F1HB 4B5FA 1ZWXA 5J42A 3I5VA 2DDTA 4CMNA 2ISIA 3G2CA 4F1IA 4GZ2A 2V0SA 4C1RA 1BIXA 2A3ZB 3NR8A 4AWNA 3G38A 5DFJA 3GA6A 1HD7A 5DV4A 4B5MA 4B5HA 2V0RA 4CMLA 1DEWA 3TEBA 5DG0A 3G3CA 2O3HA 3FZIA 2DNJA 4IEMA 2F2FB 4B5JA 3W2YA 1Y21A 2XSWA 3L1WA 5CFGA 3G3YA 2O3CA 2IMQX 5INMA 5INOA 5INLA 5INNA 5EWTA 5DFHA 5HT2A 2D1KB 3G6SA 5INKA 4QHDA 4L1ZA 3W2XA 1DE8A 5A7JA 5INPA 3WCXA 3NGQA 4RUWA 5INQA 5CFEA 4QH9A 4K6LF 1WDUA 4L21A 1SI6X 3NGNA 3DNIA 2JC5A 2A40B 3I48A 5J3ZA 1DE9A 1AKOA 1SR4B 4GYZA 4JG3A 4A9CA 4FVAA 1I9ZA
chains in the Genus database with same CATH superfamily
3MTCA 2F1NA 5DFFA 5J3PA 3MPRA 2A42B 3G1KA 3G8VA 3K55A 5J3SA 5A7IA 2VOAA 3G00A 4B5GA 1VYBA 2EI9A 4B5IA 4FPVA 2A41B 3CJCD 4GZ0A 3NGOA 4F1HA 4L1YA 2J63A 1YJHA 3G2DA 1ATND 3I46A 5DV2A 1I9YA 5J8NA 2UYRX 3G0AA 4L20A 3G4TA 1NTFA 4PUQA 3U8UA 2DDRA 4GZ1A 3G91A 2DDSA 1E9NA 3N9VA 4GEWA 3I41A 4F1RA 4QHEA 1DNKA 2JC4A 3G0RA 3W3DB 4LNDA 5DFIA 4F1HB 4B5FA 1ZWXA 5J42A 3I5VA 2DDTA 4CMNA 2ISIA 3G2CA 4F1IA 4GZ2A 2V0SA 4C1RA 1BIXA 2A3ZB 3NR8A 4AWNA 3G38A 5DFJA 3GA6A 1HD7A 5DV4A 4B5MA 4B5HA 2V0RA 4CMLA 1DEWA 3TEBA 5DG0A 3G3CA 2O3HA 3FZIA 2DNJA 4IEMA 2F2FB 4B5JA 3W2YA 1Y21A 2XSWA 3L1WA 5CFGA 3G3YA 2O3CA 2IMQX 5INMA 5INOA 5INLA 5INNA 5EWTA 5DFHA 5HT2A 2D1KB 3G6SA 5INKA 4QHDA 4L1ZA 3W2XA 1DE8A 5A7JA 5INPA 3WCXA 3NGQA 4RUWA 5INQA 5CFEA 4QH9A 4K6LF 1WDUA 4L21A 1SI6X 3NGNA 3DNIA 2JC5A 2A40B 3I48A 5J3ZA 1DE9A 1AKOA 1SR4B 4GYZA 4JG3A 4A9CA 4FVAA 1I9ZA
chains in the Genus database with same CATH topology
3MTCA 2F1NA 5DFFA 5J3PA 3MPRA 2A42B 3G1KA 3G8VA 3K55A 5J3SA 5A7IA 2VOAA 3G00A 4B5GA 1VYBA 2EI9A 4B5IA 4FPVA 2A41B 3CJCD 4GZ0A 3NGOA 4F1HA 4L1YA 2J63A 1YJHA 3G2DA 1ATND 3I46A 5DV2A 1I9YA 5J8NA 2UYRX 3G0AA 4L20A 3G4TA 1NTFA 4PUQA 3U8UA 2DDRA 4GZ1A 3G91A 2DDSA 1E9NA 3N9VA 4GEWA 3I41A 4F1RA 4QHEA 1DNKA 2JC4A 3G0RA 3W3DB 4LNDA 5DFIA 4F1HB 4B5FA 1ZWXA 5J42A 3I5VA 2DDTA 4CMNA 2ISIA 3G2CA 4F1IA 4GZ2A 2V0SA 4C1RA 1BIXA 2A3ZB 3NR8A 4AWNA 3G38A 5DFJA 3GA6A 1HD7A 5DV4A 4B5MA 4B5HA 2V0RA 4CMLA 1DEWA 3TEBA 5DG0A 3G3CA 2O3HA 3FZIA 2DNJA 4IEMA 2F2FB 4B5JA 3W2YA 1Y21A 2XSWA 3L1WA 5CFGA 3G3YA 2O3CA 2IMQX 5INMA 5INOA 5INLA 5INNA 5EWTA 5DFHA 5HT2A 2D1KB 3G6SA 5INKA 4QHDA 4L1ZA 3W2XA 1DE8A 5A7JA 5INPA 3WCXA 3NGQA 4RUWA 5INQA 5CFEA 4QH9A 4K6LF 1WDUA 4L21A 1SI6X 3NGNA 3DNIA 2JC5A 2A40B 3I48A 5J3ZA 1DE9A 1AKOA 1SR4B 4GYZA 4JG3A 4A9CA 4FVAA 1I9ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MTC A;  2F1N A;  5DFF A;  5J3P A;  3MPR A;  2A42 B;  3G1K A;  3G8V A;  3K55 A;  5J3S A;  5A7I A;  2VOA A;  3G00 A;  4B5G A;  1VYB A;  2EI9 A;  4B5I A;  4FPV A;  2A41 B;  3CJC D;  4GZ0 A;  3NGO A;  4F1H A;  4L1Y A;  2J63 A;  1YJH A;  3G2D A;  1ATN D;  3I46 A;  5DV2 A;  1I9Y A;  5J8N A;  2UYR X;  3G0A A;  4L20 A;  3G4T A;  1NTF A;  4PUQ A;  3U8U A;  2DDR A;  4GZ1 A;  3G91 A;  2DDS A;  1E9N A;  3N9V A;  4GEW A;  3I41 A;  4F1R A;  4QHE A;  1DNK A;  2JC4 A;  3G0R A;  3W3D B;  4LND A;  5DFI A;  4F1H B;  4B5F A;  1ZWX A;  5J42 A;  3I5V A;  2DDT A;  4CMN A;  2ISI A;  3G2C A;  4F1I A;  4GZ2 A;  2V0S A;  4C1R A;  1BIX A;  2A3Z B;  3NR8 A;  4AWN A;  3G38 A;  5DFJ A;  3GA6 A;  1HD7 A;  5DV4 A;  4B5M A;  4B5H A;  2V0R A;  4CML A;  1DEW A;  3TEB A;  5DG0 A;  3G3C A;  2O3H A;  3FZI A;  2DNJ A;  4IEM A;  2F2F B;  4B5J A;  3W2Y A;  1Y21 A;  2XSW A;  3L1W A;  5CFG A;  3G3Y A;  2O3C A;  2IMQ X;  5INM A;  5INO A;  5INL A;  5INN A;  5EWT A;  5DFH A;  5HT2 A;  2D1K B;  3G6S A;  5INK A;  4QHD A;  4L1Z A;  3W2X A;  1DE8 A;  5A7J A;  5INP A;  3WCX A;  3NGQ A;  4RUW A;  5INQ A;  5CFE A;  4QH9 A;  4K6L F;  1WDU A;  4L21 A;  1SI6 X;  3NGN A;  3DNI A;  2JC5 A;  2A40 B;  3I48 A;  5J3Z A;  1DE9 A;  1AKO A;  1SR4 B;  4GYZ A;  4JG3 A;  4A9C A;  4FVA A;  1I9Z A; 
#chains in the Genus database with same CATH topology
 3MTC A;  2F1N A;  5DFF A;  5J3P A;  3MPR A;  2A42 B;  3G1K A;  3G8V A;  3K55 A;  5J3S A;  5A7I A;  2VOA A;  3G00 A;  4B5G A;  1VYB A;  2EI9 A;  4B5I A;  4FPV A;  2A41 B;  3CJC D;  4GZ0 A;  3NGO A;  4F1H A;  4L1Y A;  2J63 A;  1YJH A;  3G2D A;  1ATN D;  3I46 A;  5DV2 A;  1I9Y A;  5J8N A;  2UYR X;  3G0A A;  4L20 A;  3G4T A;  1NTF A;  4PUQ A;  3U8U A;  2DDR A;  4GZ1 A;  3G91 A;  2DDS A;  1E9N A;  3N9V A;  4GEW A;  3I41 A;  4F1R A;  4QHE A;  1DNK A;  2JC4 A;  3G0R A;  3W3D B;  4LND A;  5DFI A;  4F1H B;  4B5F A;  1ZWX A;  5J42 A;  3I5V A;  2DDT A;  4CMN A;  2ISI A;  3G2C A;  4F1I A;  4GZ2 A;  2V0S A;  4C1R A;  1BIX A;  2A3Z B;  3NR8 A;  4AWN A;  3G38 A;  5DFJ A;  3GA6 A;  1HD7 A;  5DV4 A;  4B5M A;  4B5H A;  2V0R A;  4CML A;  1DEW A;  3TEB A;  5DG0 A;  3G3C A;  2O3H A;  3FZI A;  2DNJ A;  4IEM A;  2F2F B;  4B5J A;  3W2Y A;  1Y21 A;  2XSW A;  3L1W A;  5CFG A;  3G3Y A;  2O3C A;  2IMQ X;  5INM A;  5INO A;  5INL A;  5INN A;  5EWT A;  5DFH A;  5HT2 A;  2D1K B;  3G6S A;  5INK A;  4QHD A;  4L1Z A;  3W2X A;  1DE8 A;  5A7J A;  5INP A;  3WCX A;  3NGQ A;  4RUW A;  5INQ A;  5CFE A;  4QH9 A;  4K6L F;  1WDU A;  4L21 A;  1SI6 X;  3NGN A;  3DNI A;  2JC5 A;  2A40 B;  3I48 A;  5J3Z A;  1DE9 A;  1AKO A;  1SR4 B;  4GYZ A;  4JG3 A;  4A9C A;  4FVA A;  1I9Z A; 
#chains in the Genus database with same CATH homology
 3MTC A;  2F1N A;  5DFF A;  5J3P A;  3MPR A;  2A42 B;  3G1K A;  3G8V A;  3K55 A;  5J3S A;  5A7I A;  2VOA A;  3G00 A;  4B5G A;  1VYB A;  2EI9 A;  4B5I A;  4FPV A;  2A41 B;  3CJC D;  4GZ0 A;  3NGO A;  4F1H A;  4L1Y A;  2J63 A;  1YJH A;  3G2D A;  1ATN D;  3I46 A;  5DV2 A;  1I9Y A;  5J8N A;  2UYR X;  3G0A A;  4L20 A;  3G4T A;  1NTF A;  4PUQ A;  3U8U A;  2DDR A;  4GZ1 A;  3G91 A;  2DDS A;  1E9N A;  3N9V A;  4GEW A;  3I41 A;  4F1R A;  4QHE A;  1DNK A;  2JC4 A;  3G0R A;  3W3D B;  4LND A;  5DFI A;  4F1H B;  4B5F A;  1ZWX A;  5J42 A;  3I5V A;  2DDT A;  4CMN A;  2ISI A;  3G2C A;  4F1I A;  4GZ2 A;  2V0S A;  4C1R A;  1BIX A;  2A3Z B;  3NR8 A;  4AWN A;  3G38 A;  5DFJ A;  3GA6 A;  1HD7 A;  5DV4 A;  4B5M A;  4B5H A;  2V0R A;  4CML A;  1DEW A;  3TEB A;  5DG0 A;  3G3C A;  2O3H A;  3FZI A;  2DNJ A;  4IEM A;  2F2F B;  4B5J A;  3W2Y A;  1Y21 A;  2XSW A;  3L1W A;  5CFG A;  3G3Y A;  2O3C A;  2IMQ X;  5INM A;  5INO A;  5INL A;  5INN A;  5EWT A;  5DFH A;  5HT2 A;  2D1K B;  3G6S A;  5INK A;  4QHD A;  4L1Z A;  3W2X A;  1DE8 A;  5A7J A;  5INP A;  3WCX A;  3NGQ A;  4RUW A;  5INQ A;  5CFE A;  4QH9 A;  4K6L F;  1WDU A;  4L21 A;  1SI6 X;  3NGN A;  3DNI A;  2JC5 A;  2A40 B;  3I48 A;  5J3Z A;  1DE9 A;  1AKO A;  1SR4 B;  4GYZ A;  4JG3 A;  4A9C A;  4FVA A;  1I9Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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