4B5MA

Neisseria ap endonuclease bound to the substrate with a cytosine orphan base
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
257
structure length
257
Chain Sequence
MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADLSADMKNPHGMHGHWHCAEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQQVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLKNWKGNQKNSGFLPEEREWIGKVIHKLGWTDMWRTLYPDVPGYTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHVYKDEKFSDHAPLVVEYDYA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Neisseria meningitidis
molecule keywords PUTATIVE EXODEOXYRIBONUCLEASE
total genus 81
structure length 257
sequence length 257
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2012-08-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4b5mA00
3TEBA 3W3DB 3G4TA 3G0AA 3WCXA 1SI6X 1WDUA 3G38A 4C1RA 5INQA 4GYZA 3U8UA 3NGNA 5DG0A 1E9NA 2O3CA 2JC4A 2JC5A 3GA6A 5CFEA 5DFHA 4GZ1A 4RUWA 2DDSA 3G2DA 4QH9A 3G3CA 2J63A 3NR8A 3G0RA 3G2CA 4GZ0A 4F1RA 2IMQX 4QHEA 5HT2A 4F1HA 5INMA 3NGQA 4GEWA 2V0RA 4AWNA 3G1KA 3FZIA 3DNIA 3I48A 3G00A 4A9CA 3NGOA 2EI9A 1ATND 2O3HA 3G91A 3W2XA 1I9YA 1VYBA 2DDRA 2F2FB 5DFFA 5J8NA 1DE8A 5J3ZA 4F1IA 5J42A 2VOAA 3G6SA 4B5GA 3K55A 4LNDA 4PUQA 1BIXA 3I46A 5INKA 3L1WA 1HD7A 5INNA 2UYRX 2V0SA 2XSWA 3I41A 4CMNA 4L20A 5EWTA 4B5MA 3CJCD 2DNJA 3I5VA 4B5JA 4FPVA 5A7IA 5DV2A 4L1YA 5J3SA 2A42B 4L21A 5CFGA 1DNKA 5INOA 4L1ZA 1SR4B 1YJHA 1ZWXA 1Y21A 4K6LF 1DE9A 2A3ZB 5A7JA 4IEMA 5DFIA 3G3YA 4FVAA 2D1KB 1I9ZA 2A41B 5INPA 5J3PA 4B5IA 2DDTA 3N9VA 5DV4A 1NTFA 4QHDA 3G8VA 4B5FA 2ISIA 5INLA 3MTCA 4CMLA 4F1HB 4JG3A 3W2YA 2A40B 1AKOA 2F1NA 4GZ2A 5DFJA 3MPRA 1DEWA 4B5HA
chains in the Genus database with same CATH superfamily
3TEBA 3W3DB 3G4TA 3G0AA 3WCXA 1SI6X 1WDUA 3G38A 4C1RA 5INQA 4GYZA 3U8UA 3NGNA 5DG0A 1E9NA 2O3CA 2JC4A 2JC5A 3GA6A 5CFEA 5DFHA 4GZ1A 4RUWA 2DDSA 3G2DA 4QH9A 3G3CA 2J63A 3NR8A 3G0RA 3G2CA 4GZ0A 4F1RA 2IMQX 4QHEA 5HT2A 4F1HA 5INMA 3NGQA 4GEWA 2V0RA 4AWNA 3G1KA 3FZIA 3DNIA 3I48A 3G00A 4A9CA 3NGOA 2EI9A 1ATND 2O3HA 3G91A 3W2XA 1I9YA 1VYBA 2DDRA 2F2FB 5DFFA 5J8NA 1DE8A 5J3ZA 4F1IA 5J42A 2VOAA 3G6SA 4B5GA 3K55A 4LNDA 4PUQA 1BIXA 3I46A 5INKA 3L1WA 1HD7A 5INNA 2UYRX 2V0SA 2XSWA 3I41A 4CMNA 4L20A 5EWTA 4B5MA 3CJCD 2DNJA 3I5VA 4B5JA 4FPVA 5A7IA 5DV2A 4L1YA 5J3SA 2A42B 4L21A 5CFGA 1DNKA 5INOA 4L1ZA 1SR4B 1YJHA 1ZWXA 1Y21A 4K6LF 1DE9A 2A3ZB 5A7JA 4IEMA 5DFIA 3G3YA 4FVAA 2D1KB 1I9ZA 2A41B 5INPA 5J3PA 4B5IA 2DDTA 3N9VA 5DV4A 1NTFA 4QHDA 3G8VA 4B5FA 2ISIA 5INLA 3MTCA 4CMLA 4F1HB 4JG3A 3W2YA 2A40B 1AKOA 2F1NA 4GZ2A 5DFJA 3MPRA 1DEWA 4B5HA
chains in the Genus database with same CATH topology
3TEBA 3W3DB 3G4TA 3G0AA 3WCXA 1SI6X 1WDUA 3G38A 4C1RA 5INQA 4GYZA 3U8UA 3NGNA 5DG0A 1E9NA 2O3CA 2JC4A 2JC5A 3GA6A 5CFEA 5DFHA 4GZ1A 4RUWA 2DDSA 3G2DA 4QH9A 3G3CA 2J63A 3NR8A 3G0RA 3G2CA 4GZ0A 4F1RA 2IMQX 4QHEA 5HT2A 4F1HA 5INMA 3NGQA 4GEWA 2V0RA 4AWNA 3G1KA 3FZIA 3DNIA 3I48A 3G00A 4A9CA 3NGOA 2EI9A 1ATND 2O3HA 3G91A 3W2XA 1I9YA 1VYBA 2DDRA 2F2FB 5DFFA 5J8NA 1DE8A 5J3ZA 4F1IA 5J42A 2VOAA 3G6SA 4B5GA 3K55A 4LNDA 4PUQA 1BIXA 3I46A 5INKA 3L1WA 1HD7A 5INNA 2UYRX 2V0SA 2XSWA 3I41A 4CMNA 4L20A 5EWTA 4B5MA 3CJCD 2DNJA 3I5VA 4B5JA 4FPVA 5A7IA 5DV2A 4L1YA 5J3SA 2A42B 4L21A 5CFGA 1DNKA 5INOA 4L1ZA 1SR4B 1YJHA 1ZWXA 1Y21A 4K6LF 1DE9A 2A3ZB 5A7JA 4IEMA 5DFIA 3G3YA 4FVAA 2D1KB 1I9ZA 2A41B 5INPA 5J3PA 4B5IA 2DDTA 3N9VA 5DV4A 1NTFA 4QHDA 3G8VA 4B5FA 2ISIA 5INLA 3MTCA 4CMLA 4F1HB 4JG3A 3W2YA 2A40B 1AKOA 2F1NA 4GZ2A 5DFJA 3MPRA 1DEWA 4B5HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TEB A;  3W3D B;  3G4T A;  3G0A A;  3WCX A;  1SI6 X;  1WDU A;  3G38 A;  4C1R A;  5INQ A;  4GYZ A;  3U8U A;  3NGN A;  5DG0 A;  1E9N A;  2O3C A;  2JC4 A;  2JC5 A;  3GA6 A;  5CFE A;  5DFH A;  4GZ1 A;  4RUW A;  2DDS A;  3G2D A;  4QH9 A;  3G3C A;  2J63 A;  3NR8 A;  3G0R A;  3G2C A;  4GZ0 A;  4F1R A;  2IMQ X;  4QHE A;  5HT2 A;  4F1H A;  5INM A;  3NGQ A;  4GEW A;  2V0R A;  4AWN A;  3G1K A;  3FZI A;  3DNI A;  3I48 A;  3G00 A;  4A9C A;  3NGO A;  2EI9 A;  1ATN D;  2O3H A;  3G91 A;  3W2X A;  1I9Y A;  1VYB A;  2DDR A;  2F2F B;  5DFF A;  5J8N A;  1DE8 A;  5J3Z A;  4F1I A;  5J42 A;  2VOA A;  3G6S A;  4B5G A;  3K55 A;  4LND A;  4PUQ A;  1BIX A;  3I46 A;  5INK A;  3L1W A;  1HD7 A;  5INN A;  2UYR X;  2V0S A;  2XSW A;  3I41 A;  4CMN A;  4L20 A;  5EWT A;  4B5M A;  3CJC D;  2DNJ A;  3I5V A;  4B5J A;  4FPV A;  5A7I A;  5DV2 A;  4L1Y A;  5J3S A;  2A42 B;  4L21 A;  5CFG A;  1DNK A;  5INO A;  4L1Z A;  1SR4 B;  1YJH A;  1ZWX A;  1Y21 A;  4K6L F;  1DE9 A;  2A3Z B;  5A7J A;  4IEM A;  5DFI A;  3G3Y A;  4FVA A;  2D1K B;  1I9Z A;  2A41 B;  5INP A;  5J3P A;  4B5I A;  2DDT A;  3N9V A;  5DV4 A;  1NTF A;  4QHD A;  3G8V A;  4B5F A;  2ISI A;  5INL A;  3MTC A;  4CML A;  4F1H B;  4JG3 A;  3W2Y A;  2A40 B;  1AKO A;  2F1N A;  4GZ2 A;  5DFJ A;  3MPR A;  1DEW A;  4B5H A; 
#chains in the Genus database with same CATH topology
 3TEB A;  3W3D B;  3G4T A;  3G0A A;  3WCX A;  1SI6 X;  1WDU A;  3G38 A;  4C1R A;  5INQ A;  4GYZ A;  3U8U A;  3NGN A;  5DG0 A;  1E9N A;  2O3C A;  2JC4 A;  2JC5 A;  3GA6 A;  5CFE A;  5DFH A;  4GZ1 A;  4RUW A;  2DDS A;  3G2D A;  4QH9 A;  3G3C A;  2J63 A;  3NR8 A;  3G0R A;  3G2C A;  4GZ0 A;  4F1R A;  2IMQ X;  4QHE A;  5HT2 A;  4F1H A;  5INM A;  3NGQ A;  4GEW A;  2V0R A;  4AWN A;  3G1K A;  3FZI A;  3DNI A;  3I48 A;  3G00 A;  4A9C A;  3NGO A;  2EI9 A;  1ATN D;  2O3H A;  3G91 A;  3W2X A;  1I9Y A;  1VYB A;  2DDR A;  2F2F B;  5DFF A;  5J8N A;  1DE8 A;  5J3Z A;  4F1I A;  5J42 A;  2VOA A;  3G6S A;  4B5G A;  3K55 A;  4LND A;  4PUQ A;  1BIX A;  3I46 A;  5INK A;  3L1W A;  1HD7 A;  5INN A;  2UYR X;  2V0S A;  2XSW A;  3I41 A;  4CMN A;  4L20 A;  5EWT A;  4B5M A;  3CJC D;  2DNJ A;  3I5V A;  4B5J A;  4FPV A;  5A7I A;  5DV2 A;  4L1Y A;  5J3S A;  2A42 B;  4L21 A;  5CFG A;  1DNK A;  5INO A;  4L1Z A;  1SR4 B;  1YJH A;  1ZWX A;  1Y21 A;  4K6L F;  1DE9 A;  2A3Z B;  5A7J A;  4IEM A;  5DFI A;  3G3Y A;  4FVA A;  2D1K B;  1I9Z A;  2A41 B;  5INP A;  5J3P A;  4B5I A;  2DDT A;  3N9V A;  5DV4 A;  1NTF A;  4QHD A;  3G8V A;  4B5F A;  2ISI A;  5INL A;  3MTC A;  4CML A;  4F1H B;  4JG3 A;  3W2Y A;  2A40 B;  1AKO A;  2F1N A;  4GZ2 A;  5DFJ A;  3MPR A;  1DEW A;  4B5H A; 
#chains in the Genus database with same CATH homology
 3TEB A;  3W3D B;  3G4T A;  3G0A A;  3WCX A;  1SI6 X;  1WDU A;  3G38 A;  4C1R A;  5INQ A;  4GYZ A;  3U8U A;  3NGN A;  5DG0 A;  1E9N A;  2O3C A;  2JC4 A;  2JC5 A;  3GA6 A;  5CFE A;  5DFH A;  4GZ1 A;  4RUW A;  2DDS A;  3G2D A;  4QH9 A;  3G3C A;  2J63 A;  3NR8 A;  3G0R A;  3G2C A;  4GZ0 A;  4F1R A;  2IMQ X;  4QHE A;  5HT2 A;  4F1H A;  5INM A;  3NGQ A;  4GEW A;  2V0R A;  4AWN A;  3G1K A;  3FZI A;  3DNI A;  3I48 A;  3G00 A;  4A9C A;  3NGO A;  2EI9 A;  1ATN D;  2O3H A;  3G91 A;  3W2X A;  1I9Y A;  1VYB A;  2DDR A;  2F2F B;  5DFF A;  5J8N A;  1DE8 A;  5J3Z A;  4F1I A;  5J42 A;  2VOA A;  3G6S A;  4B5G A;  3K55 A;  4LND A;  4PUQ A;  1BIX A;  3I46 A;  5INK A;  3L1W A;  1HD7 A;  5INN A;  2UYR X;  2V0S A;  2XSW A;  3I41 A;  4CMN A;  4L20 A;  5EWT A;  4B5M A;  3CJC D;  2DNJ A;  3I5V A;  4B5J A;  4FPV A;  5A7I A;  5DV2 A;  4L1Y A;  5J3S A;  2A42 B;  4L21 A;  5CFG A;  1DNK A;  5INO A;  4L1Z A;  1SR4 B;  1YJH A;  1ZWX A;  1Y21 A;  4K6L F;  1DE9 A;  2A3Z B;  5A7J A;  4IEM A;  5DFI A;  3G3Y A;  4FVA A;  2D1K B;  1I9Z A;  2A41 B;  5INP A;  5J3P A;  4B5I A;  2DDT A;  3N9V A;  5DV4 A;  1NTF A;  4QHD A;  3G8V A;  4B5F A;  2ISI A;  5INL A;  3MTC A;  4CML A;  4F1H B;  4JG3 A;  3W2Y A;  2A40 B;  1AKO A;  2F1N A;  4GZ2 A;  5DFJ A;  3MPR A;  1DEW A;  4B5H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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