4BKEA

Recombinant human serum albumin with palmitic acid. synthetic cationic antimicrobial peptides bind with their hydrophobic parts to drug site ii of human serum albumin
Total Genus 224
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
224
sequence length
582
structure length
582
Chain Sequence
HKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVFLGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords SERUM ALBUMIN
publication title Synthetic Cationic Antimicrobial Peptides Bind with Their Hydrophobic Parts to Drug Site II of Human Serum Albumin.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transport protein
total genus 224
structure length 582
sequence length 582
ec nomenclature
pdb deposition date 2013-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00273 Serum_albumin Serum albumin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4bkeA03
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4bkeA02
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4bkeA04
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4bkeA01
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4bkeA06
1.10.246.10 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4bkeA05
1MA9A 1HK4A 2BXQA 1E7AA 1AO6A 3LU6A 5IFOA 4L9KA 1N5UA 1BM0A 2I30A 3CX9A 5ID9A 5GHKA 2XVQA 5IIXA 1H9ZA 1GNJA 4N0UD 4LB9A 4Z69A 2BXNA 4ZBQA 3V08A 1KXPD 4L8UA 3JRYA 4BKEA 3UIVA 4J2VA 4F5UA 5DBYA 4N0FD 3JQZA 4IW1A 4E99A 4HGKA 2XVUA 4EMXA 2VUEA 1UORA 2YDFA 5IJFA 5FUOA 1HK5A 2VDBA 1TF0A 2XSIA 1E7FA 3A73A 2BXPA 2BXOA 1E7IA 2BX8A 4HGMB 5ID7A 4F5VA 4K71A 3B9MA 1HK3A 1BKEA 1LOTA 1E7HA 4JK4A 1HK2A 4LB2A 2BXLA 2BXKA 2BXGA 3TDLA 3V09A 4G04A 1E7EA 2VUFA 2XW1A 2BXAA 2BXMA 5IJEA 2XVVA 4S1YA 4G03A 3SQJA 4LUHA 2BXDA 4ZBRA 1O9XA 1GNIA 1KW2A 3V03A 4L9QA 1E7GA 5IIHA 4OT2A 1BJ5A 2XVWA 4F5TA 4F5SA 5HOZA 5DQFA 1HA2A 3LU7A 1E78A 1E7BA 5IJ5A 2BXCA 3B9LA 2BXIA 2BXHA 2BXEA 4IW2A 3LU8A 1HK1A 4K2CA 1J78A 4LA0A 2I2ZA 1E7CA 5IIUA 4PO0A 2XW0A 4LUFA 4OR0A 2BXBA 1J7EA 2BXFA
chains in the Genus database with same CATH superfamily
1MA9A 1VFIA 1HK4A 3FNMA 2BXQA 1E7AA 1AO6A 3VQIA 2OZBB 2KWFA 3H37A 3LU6A 5IFOA 4L9KA 1N5UA 2LXSA 2AJEA 3ICXA 4TQ1A 1BM0A 4ZBKA 3SIUB 2I30A 3CX9A 5ID9A 5GHKA 4MBEC 2XVQA 4WA6B 4GDLB 5IIXA 3NVKA 1H9ZA 1GNJA 4N0UD 4LB9A 3NVMA 4Z69A 2BXNA 2EFEA 4ZBQA 3W1SA 3V08A 1KXPD 4FIPB 3JRYA 2Z8JA 4L8UA 4GDXA 2AGHB 4OTUA 1VZSA 3UIVA 4BKEA 3GQXA 4J2VA 3FWCC 4F5UA 5DBYA 4N0FD 1IJGA 3ECPA 2ROHA 3JQZA 4FJCB 4IW1A 4HGKA 4E99A 2XVUA 4ZC6A 4EMXA 1MIWA 2VUEA 1UORA 4NAWB 3MHSB 2YDFA 1JNBA 5IJFA 5FUOA 2Z8IA 1FOUA 5GIOA 1HK5A 3BPJA 4DHXB 5B5TA 3GQUA 2LQHA 2VDBA 1TF0A 2DG5A 2XSIA 2EFHA 1E7FA 3A73A 4W4UB 2BXPA 2V36A 2BXOA 1E7IA 1MIYA 4C31B 2BX8A 1MM8A 4I9OA 4HGMB 5ID7A 4F5VA 4K71A 4OTTA 2QMCA 2DYMA 3M99C 3B9MA 4GDKB 1HK3A 4GG2A 3A75A 1BKEA 1LOTA 3GA9L 1E7HA 4FK5B 4JK4A 3SIVB 2DBWA 2JUHA 1HK2A 4LB2A 2BXLA 2E0XA 2BXKA 1MIVA 4DM0A 2XMOA 2BXGA 2EFDA 3WHSA 4N3ZA 2QM6A 2DYOA 3TDLA 3MHHB 5D7GA 3V09A 4D7XA 1MUSA 1SB0A 5GINA 4G04A 4ZUXV 1E7EA 2OT3A 2VUFA 2XW1A 3FWBC 1H5WA 2BXAA 2LOQA 4TQ0A 3NMUA 2BXMA 2EFCA 5IJEA 2XVVA 4S1YA 4G03A 3SQJA 3KIKA 4LUHA 2BXDA 4Z9OA 4ZBRA 3NVIA 1NT2B 1O9XA 1GNIA 2KBZA 1KW2A 3PLAA 3V03A 2LXTA 1KDXA 2CKXA 4L9QA 1MUHA 1E7GA 3WHQA 2GUTA 5IIHA 4OT2A 1BJ5A 2XVWA 4F5TA 4F5SA 5HOZA 5DQFA 1HA2A 2K0NA 3LU7A 4M70B 1E78A 1E7BA 5IJ5A 5GIPA 3KJLA 2BXCA 2QHBA 3B9LA 3WHRA 2DBUA 2BXIA 2BXHA 2NNWA 2BXEA 1LNSA 3LU8A 4G01A 1HK1A 2E0YA 2LQIA 1J78A 2Z8KA 4IW2A 4K2CA 4LA0A 2I2ZA 4BY9C 1TXUA 1E7CA 2DBXA 5IIUA 4PO0A 4ZCGA 2XW0A 5BPKA 3H3AA 3G9KD 4LUFA 4OR0A 2BXBA 1J7EA 2NQOA 2BXFA
chains in the Genus database with same CATH topology
1MA9A 1VFIA 1HK4A 3FNMA 2BXQA 1E7AA 1AO6A 3VQIA 2OZBB 3H37A 3LU6A 5IFOA 4L9KA 1N5UA 2AJEA 3ICXA 4TQ1A 1BM0A 4ZBKA 3SIUB 2I30A 3CX9A 5ID9A 5GHKA 4MBEC 2XVQA 4WA6B 4GDLB 5IIXA 3NVKA 1H9ZA 1GNJA 4N0UD 4LB9A 3NVMA 4Z69A 2BXNA 2EFEA 4ZBQA 3W1SA 3V08A 1KXPD 4FIPB 3JRYA 2Z8JA 4L8UA 4GDXA 4OTUA 1VZSA 3UIVA 4BKEA 3GQXA 4J2VA 3FWCC 4F5UA 5DBYA 4N0FD 1IJGA 2ROHA 3JQZA 4FJCB 4IW1A 4HGKA 4E99A 2XVUA 4ZC6A 4EMXA 1MIWA 2VUEA 1UORA 4NAWB 3MHSB 2YDFA 1JNBA 5IJFA 5FUOA 2Z8IA 1FOUA 5GIOA 1HK5A 4DHXB 5B5TA 3GQUA 2VDBA 1TF0A 2DG5A 2XSIA 2EFHA 1E7FA 3A73A 4W4UB 2BXPA 2V36A 2BXOA 1E7IA 1MIYA 4C31B 2BX8A 4HGMB 5ID7A 4F5VA 4K71A 4OTTA 2QMCA 2DYMA 3M99C 3B9MA 4GDKB 1HK3A 4GG2A 3A75A 1BKEA 1LOTA 3GA9L 1E7HA 4FK5B 4JK4A 3SIVB 2DBWA 2JUHA 1HK2A 4LB2A 2BXLA 2E0XA 2BXKA 1MIVA 2XMOA 2BXGA 2EFDA 3WHSA 4N3ZA 2QM6A 2DYOA 3TDLA 3MHHB 5D7GA 3V09A 5GINA 4G04A 4ZUXV 1E7EA 2OT3A 2VUFA 2XW1A 3FWBC 1H5WA 2BXAA 2LOQA 4TQ0A 3NMUA 2BXMA 2EFCA 5IJEA 2XVVA 4S1YA 4G03A 3SQJA 3KIKA 4LUHA 2BXDA 4Z9OA 4ZBRA 3NVIA 1NT2B 1O9XA 1GNIA 2KBZA 1KW2A 3V03A 2CKXA 4L9QA 1E7GA 3WHQA 5IIHA 4OT2A 1BJ5A 2XVWA 4F5TA 4F5SA 5HOZA 5DQFA 1HA2A 3LU7A 4M70B 5GIPA 1E78A 1E7BA 5IJ5A 3KJLA 2BXCA 2QHBA 3B9LA 3WHRA 2DBUA 2BXIA 2BXHA 2NNWA 2BXEA 1LNSA 3LU8A 4G01A 1HK1A 2E0YA 2Z8KA 1J78A 4IW2A 4K2CA 3PLAA 4LA0A 2I2ZA 4BY9C 1TXUA 1E7CA 2DBXA 5IIUA 4PO0A 4ZCGA 2XW0A 5BPKA 3H3AA 3G9KD 4LUFA 4OR0A 2BXBA 1J7EA 2NQOA 2BXFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MA9 A;  1HK4 A;  2BXQ A;  1E7A A;  1AO6 A;  3LU6 A;  5IFO A;  4L9K A;  1N5U A;  1BM0 A;  2I30 A;  3CX9 A;  5ID9 A;  5GHK A;  2XVQ A;  5IIX A;  1H9Z A;  1GNJ A;  4N0U D;  4LB9 A;  4Z69 A;  2BXN A;  4ZBQ A;  3V08 A;  1KXP D;  4L8U A;  3JRY A;  4BKE A;  3UIV A;  4J2V A;  4F5U A;  5DBY A;  4N0F D;  3JQZ A;  4IW1 A;  4E99 A;  4HGK A;  2XVU A;  4EMX A;  2VUE A;  1UOR A;  2YDF A;  5IJF A;  5FUO A;  1HK5 A;  2VDB A;  1TF0 A;  2XSI A;  1E7F A;  3A73 A;  2BXP A;  2BXO A;  1E7I A;  2BX8 A;  4HGM B;  5ID7 A;  4F5V A;  4K71 A;  3B9M A;  1HK3 A;  1BKE A;  1LOT A;  1E7H A;  4JK4 A;  1HK2 A;  4LB2 A;  2BXL A;  2BXK A;  2BXG A;  3TDL A;  3V09 A;  4G04 A;  1E7E A;  2VUF A;  2XW1 A;  2BXA A;  2BXM A;  5IJE A;  2XVV A;  4S1Y A;  4G03 A;  3SQJ A;  4LUH A;  2BXD A;  4ZBR A;  1O9X A;  1GNI A;  1KW2 A;  3V03 A;  4L9Q A;  1E7G A;  5IIH A;  4OT2 A;  1BJ5 A;  2XVW A;  4F5T A;  4F5S A;  5HOZ A;  5DQF A;  1HA2 A;  3LU7 A;  1E78 A;  1E7B A;  5IJ5 A;  2BXC A;  3B9L A;  2BXI A;  2BXH A;  2BXE A;  4IW2 A;  3LU8 A;  1HK1 A;  4K2C A;  1J78 A;  4LA0 A;  2I2Z A;  1E7C A;  5IIU A;  4PO0 A;  2XW0 A;  4LUF A;  4OR0 A;  2BXB A;  1J7E A;  2BXF A; 
#chains in the Genus database with same CATH topology
 1MA9 A;  1VFI A;  1HK4 A;  3FNM A;  2BXQ A;  1E7A A;  1AO6 A;  3VQI A;  2OZB B;  2KWF A;  3H37 A;  3LU6 A;  5IFO A;  4L9K A;  1N5U A;  2LXS A;  2AJE A;  3ICX A;  4TQ1 A;  1BM0 A;  4ZBK A;  3SIU B;  2I30 A;  3CX9 A;  5ID9 A;  5GHK A;  4MBE C;  2XVQ A;  4WA6 B;  4GDL B;  5IIX A;  3NVK A;  1H9Z A;  1GNJ A;  4N0U D;  4LB9 A;  3NVM A;  4Z69 A;  2BXN A;  2EFE A;  4ZBQ A;  3W1S A;  3V08 A;  1KXP D;  4FIP B;  3JRY A;  2Z8J A;  4L8U A;  4GDX A;  2AGH B;  4OTU A;  1VZS A;  3UIV A;  4BKE A;  3GQX A;  4J2V A;  3FWC C;  4F5U A;  5DBY A;  4N0F D;  1IJG A;  3ECP A;  2ROH A;  3JQZ A;  4FJC B;  4IW1 A;  4HGK A;  4E99 A;  2XVU A;  4ZC6 A;  4EMX A;  1MIW A;  2VUE A;  1UOR A;  4NAW B;  3MHS B;  2YDF A;  1JNB A;  5IJF A;  5FUO A;  2Z8I A;  1FOU A;  5GIO A;  1HK5 A;  3BPJ A;  4DHX B;  5B5T A;  3GQU A;  2LQH A;  2VDB A;  1TF0 A;  2DG5 A;  2XSI A;  2EFH A;  1E7F A;  3A73 A;  4W4U B;  2BXP A;  2V36 A;  2BXO A;  1E7I A;  1MIY A;  4C31 B;  2BX8 A;  1MM8 A;  4I9O A;  4HGM B;  5ID7 A;  4F5V A;  4K71 A;  4OTT A;  2QMC A;  2DYM A;  3M99 C;  3B9M A;  4GDK B;  1HK3 A;  4GG2 A;  3A75 A;  1BKE A;  1LOT A;  3GA9 L;  1E7H A;  4FK5 B;  4JK4 A;  3SIV B;  2DBW A;  2JUH A;  1HK2 A;  4LB2 A;  2BXL A;  2E0X A;  2BXK A;  1MIV A;  4DM0 A;  2XMO A;  2BXG A;  2EFD A;  3WHS A;  4N3Z A;  2QM6 A;  2DYO A;  3TDL A;  3MHH B;  5D7G A;  3V09 A;  4D7X A;  1MUS A;  1SB0 A;  5GIN A;  4G04 A;  4ZUX V;  1E7E A;  2OT3 A;  2VUF A;  2XW1 A;  3FWB C;  1H5W A;  2BXA A;  2LOQ A;  4TQ0 A;  3NMU A;  2BXM A;  2EFC A;  5IJE A;  2XVV A;  4S1Y A;  4G03 A;  3SQJ A;  3KIK A;  4LUH A;  2BXD A;  4Z9O A;  4ZBR A;  3NVI A;  1NT2 B;  1O9X A;  1GNI A;  2KBZ A;  1KW2 A;  3PLA A;  3V03 A;  2LXT A;  1KDX A;  2CKX A;  4L9Q A;  1MUH A;  1E7G A;  3WHQ A;  2GUT A;  5IIH A;  4OT2 A;  1BJ5 A;  2XVW A;  4F5T A;  4F5S A;  5HOZ A;  5DQF A;  1HA2 A;  2K0N A;  3LU7 A;  4M70 B;  1E78 A;  1E7B A;  5IJ5 A;  5GIP A;  3KJL A;  2BXC A;  2QHB A;  3B9L A;  3WHR A;  2DBU A;  2BXI A;  2BXH A;  2NNW A;  2BXE A;  1LNS A;  3LU8 A;  4G01 A;  1HK1 A;  2E0Y A;  2LQI A;  1J78 A;  2Z8K A;  4IW2 A;  4K2C A;  4LA0 A;  2I2Z A;  4BY9 C;  1TXU A;  1E7C A;  2DBX A;  5IIU A;  4PO0 A;  4ZCG A;  2XW0 A;  5BPK A;  3H3A A;  3G9K D;  4LUF A;  4OR0 A;  2BXB A;  1J7E A;  2NQO A;  2BXF A; 
#chains in the Genus database with same CATH homology
 1MA9 A;  1VFI A;  1HK4 A;  3FNM A;  2BXQ A;  1E7A A;  1AO6 A;  3VQI A;  2OZB B;  3H37 A;  3LU6 A;  5IFO A;  4L9K A;  1N5U A;  2AJE A;  3ICX A;  4TQ1 A;  1BM0 A;  4ZBK A;  3SIU B;  2I30 A;  3CX9 A;  5ID9 A;  5GHK A;  4MBE C;  2XVQ A;  4WA6 B;  4GDL B;  5IIX A;  3NVK A;  1H9Z A;  1GNJ A;  4N0U D;  4LB9 A;  3NVM A;  4Z69 A;  2BXN A;  2EFE A;  4ZBQ A;  3W1S A;  3V08 A;  1KXP D;  4FIP B;  3JRY A;  2Z8J A;  4L8U A;  4GDX A;  4OTU A;  1VZS A;  3UIV A;  4BKE A;  3GQX A;  4J2V A;  3FWC C;  4F5U A;  5DBY A;  4N0F D;  1IJG A;  2ROH A;  3JQZ A;  4FJC B;  4IW1 A;  4HGK A;  4E99 A;  2XVU A;  4ZC6 A;  4EMX A;  1MIW A;  2VUE A;  1UOR A;  4NAW B;  3MHS B;  2YDF A;  1JNB A;  5IJF A;  5FUO A;  2Z8I A;  1FOU A;  5GIO A;  1HK5 A;  4DHX B;  5B5T A;  3GQU A;  2VDB A;  1TF0 A;  2DG5 A;  2XSI A;  2EFH A;  1E7F A;  3A73 A;  4W4U B;  2BXP A;  2V36 A;  2BXO A;  1E7I A;  1MIY A;  4C31 B;  2BX8 A;  4HGM B;  5ID7 A;  4F5V A;  4K71 A;  4OTT A;  2QMC A;  2DYM A;  3M99 C;  3B9M A;  4GDK B;  1HK3 A;  4GG2 A;  3A75 A;  1BKE A;  1LOT A;  3GA9 L;  1E7H A;  4FK5 B;  4JK4 A;  3SIV B;  2DBW A;  2JUH A;  1HK2 A;  4LB2 A;  2BXL A;  2E0X A;  2BXK A;  1MIV A;  2XMO A;  2BXG A;  2EFD A;  3WHS A;  4N3Z A;  2QM6 A;  2DYO A;  3TDL A;  3MHH B;  5D7G A;  3V09 A;  5GIN A;  4G04 A;  4ZUX V;  1E7E A;  2OT3 A;  2VUF A;  2XW1 A;  3FWB C;  1H5W A;  2BXA A;  2LOQ A;  4TQ0 A;  3NMU A;  2BXM A;  2EFC A;  5IJE A;  2XVV A;  4S1Y A;  4G03 A;  3SQJ A;  3KIK A;  4LUH A;  2BXD A;  4Z9O A;  4ZBR A;  3NVI A;  1NT2 B;  1O9X A;  1GNI A;  2KBZ A;  1KW2 A;  3V03 A;  2CKX A;  4L9Q A;  1E7G A;  3WHQ A;  5IIH A;  4OT2 A;  1BJ5 A;  2XVW A;  4F5T A;  4F5S A;  5HOZ A;  5DQF A;  1HA2 A;  3LU7 A;  4M70 B;  5GIP A;  1E78 A;  1E7B A;  5IJ5 A;  3KJL A;  2BXC A;  2QHB A;  3B9L A;  3WHR A;  2DBU A;  2BXI A;  2BXH A;  2NNW A;  2BXE A;  1LNS A;  3LU8 A;  4G01 A;  1HK1 A;  2E0Y A;  2Z8K A;  1J78 A;  4IW2 A;  4K2C A;  3PLA A;  4LA0 A;  2I2Z A;  4BY9 C;  1TXU A;  1E7C A;  2DBX A;  5IIU A;  4PO0 A;  4ZCG A;  2XW0 A;  5BPK A;  3H3A A;  3G9K D;  4LUF A;  4OR0 A;  2BXB A;  1J7E A;  2NQO A;  2BXF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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