4BNEA

Pacsin2 interacts with membranes and actin-filaments
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
290
structure length
290
Chain Sequence
SDSFWEVGNYKRTVKRIDDGHRLCNDLMNCIHERARIEKVYAQQLTEWAKRWKQLVEKGPQYGTVERAWCAFMSEAEKVSELHLEVKGSLMNEDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAYHAACKEEKLAISRETNSKADPALNPEQLKKLQDKVERSKQDVLKTKAKYEKSLKELDNATPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKNIYRELEQNIKTADAVEDLRWFRANQGPGMSMNWPQFEDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROT
publication title Direct Interaction of Actin Filaments with F-Bar Protein Pacsin2.
pubmed doi rcsb
source organism Gallus gallus
molecule tags Endocytosis
total genus 127
structure length 290
sequence length 290
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00018 SH3_1 SH3 domain
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4bneA01
3HAIA 2X3XA 2D4CA 2Q12A 2EFLA 1X04A 3PLTA 3QWEA 4DYLA 4WPEA 1URUA 5C5BB 2C08A 3HAHA 3HAJA 2X3VA 4DCNC 2ELBA 4BNEA 2Q13A 3I2WA 4AKVA 2Z0NA 2V0OA 3Q0KA 4AVMA 4WPCA 2YKTA 3OK8A 2D1LA 1X03A 3G9GA 4NSWA 3ACOA 2RAJA 3M3WA 3DYTA 4I1QA 4FZSA 1Y2OA 3QE6A 2EFKA 3Q84A 3QNIA 4H8SA 2FICA 1I4TA 4ATMA 5C5BA 3SOGA 1I49A 2Z0VA 1I4LA 3SYVA 1WDZA 4NQIA 3CAZA 2X3WA 2RAKA 1ZWWA 2Z0OA 1I4DA 3ABHA 3LLLA 2RAIA
chains in the Genus database with same CATH superfamily
1OAOA 4WPEA 2QFFA 3CZSA 3I2WA 4E81A 5TKYA 3I39X 4JWEA 3BVTA 4AVMA 3DX0A 2F7QA 4R5LA 2MI7A 1UPXA 3O3MB 2X3WA 3LLLA 4JNFA 2YIAA 3T49A 1GNLA 3EJQA 4PO2A 4HR1B 4EZSA 4F01A 2YI9A 3BVXA 2PMRA 3BVVA 2RAJA 3FD9A 2F1BA 4JWDA 1HTYA 1TQTA 1ZWWA 2F7RA 3T46A 3UITA 4DCNC 4EZVA 1SUFA 2ELBA 2Q13A 4F00A 5KBPA 2JNSA 2YLLA 4IWPA 2EFKA 4ATMA 1HWWA 1SU7A 4JNEA 4HYBA 2F1AA 3DDFA 4EZXA 1QWNA 4AZ7A 3RPMA 3ER8C 3BLBA 3BVUA 4AZ6A 3EJPA 3D2FA 2D1LA 1X03A 3M3WA 1Y2OA 3LVTA 4FM3A 2Z0VA 3A98A 3B53X 5FLEX 3VEBA 2LXYA 4JLCA 4KIKA 3CKDA 4NPHA 2GAFD 3CV5A 4NSWA 3ACOA 2ZXQA 1JQKA 3RV0A 4AZHA 1QWUA 4HY9A 4DYLA 3D52A 2WYHA 2EX3B 5E84A 2QXLA 1TQWA 3EJSA 2F18A 2YL6A 4H6HA 2X5CA 4I1QA 3EJRA 3D50A 4H8SA 3T47A 3BUQA 2EWFA 2Q12A 3D4YA 4JWCA 3DX2A 4AZCB 3DX4A 2OO2A 4B9QA 3VKHA 1E9VA 2RT6A 2LM0A 3O3OB 3I04A 4EZOA 4EZYA 3CZNA 5C5BA 3DX3A 3F7WA 4AZCA 2YL9A 3Q0KA 3KDRA 2X3XA 2Z8YA 2KHOA 4EZNA 3ERCC 1O7DB 1LQ7A 2YKTA 1OA0A 2GA9D 4AZIA 3B52X 1YWMA 4EZPA 4NQIA 4EZTA 4IWOA 2WYIA 2ALWA 3QA8A 3BUBA 3DX1A 3LMFA 2YL8A 1W9MA 4IM2A 4KIKB 4AZBA 4UDXX 1MJGA 4UDYX 2RAKA 2WINM 1SU6A 1DKYA 2OW6A 2YIBA 2OW7A 3C7NA 3DDGA 3BUDA 4WPCA 3I01A 3G9GA 2PY6A 2YL5A 4FZSA 3ZEDA 4M0MA 1I4TA 2FYVA 3EJTA 1WDZA 2GF4A 3CAZA 4EZUA 3O3NB 4JL9A 4BNEA 2OBLA 2Z0NA 1DKXA 3ER9B 1HXKA 2YLAA 1R33A 4D8JA 2JNKA 4E3CA 4R5GA 3DYTA 3QNJA 2NCZA 2FICA 1TQVA 1E1DA 4H6IA 4IM0A 2Z0OA 3BVWA 3T48A 2D4CA 2EFLA 1X04A 3QWEA 4IW0A 5C5BB 3HAHA 2F7PA 4JWIA 4EZWA 2V0OA 4IWQA 3Q84A 3QNIA 4IM3A 3SOGA 2OZNB 3ABHA 3VEAA 1GNTA 3RV1A 1URUA 1QX1A 3DPOA 4AKVA 1R34A 3OK8A 2N3KA 4JN4A 3QE6A 1I4DA 1I49A 3SYVA 1I4LA 1R5EA 3DPPA 4HR1A 2RAIA 1GN9A 2YI8A 4FZOA 2C08A 3HAJA 2X3VA 3BUIA 1U00A 4FZPA 1OA1A 3DPQA 3CVRA 4R5IA 3OWGA 1O7DC 3KAWA 3HAIA 2ND0A 4AZ5A 1SU8A 2QKWA 3BUPA 3D51A 1TQSA 3L3PA 3EJUA 3GI7A 2ND1A 1TQUA 1E2UA 2O0I1 2OBMA 2F7OA 4G6QA 4R5KA 3PLTA 1PS3A 4EZQA 3D4ZA 4EZZA 3KAVA 4AZGA 2YIVX 5FIGA 1ZYLA 3L3OM 3T4AG 1DKZA 3D2EA 3OHXM 3B51X 4R5JA 4EZRA
chains in the Genus database with same CATH topology
3HAIA 2X3XA 2D4CA 2Q12A 2EFLA 1X04A 3PLTA 3QWEA 4DYLA 4WPEA 1URUA 5C5BB 2C08A 3HAHA 3HAJA 2X3VA 4DCNC 2ELBA 4BNEA 2Q13A 3I2WA 4AKVA 2Z0NA 2V0OA 3Q0KA 4AVMA 4WPCA 2YKTA 3OK8A 2D1LA 1X03A 3G9GA 4NSWA 3ACOA 2RAJA 3M3WA 3DYTA 4I1QA 4FZSA 1Y2OA 3QE6A 2EFKA 3Q84A 3QNIA 4H8SA 2FICA 1I4TA 4ATMA 5C5BA 3SOGA 1I49A 2Z0VA 1I4LA 3SYVA 1WDZA 4NQIA 3CAZA 2X3WA 2RAKA 1ZWWA 2Z0OA 1I4DA 3ABHA 3LLLA 2RAIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HAI A;  2X3X A;  2D4C A;  2Q12 A;  2EFL A;  1X04 A;  3PLT A;  3QWE A;  4DYL A;  4WPE A;  1URU A;  5C5B B;  2C08 A;  3HAH A;  3HAJ A;  2X3V A;  4DCN C;  2ELB A;  4BNE A;  2Q13 A;  3I2W A;  4AKV A;  2Z0N A;  2V0O A;  3Q0K A;  4AVM A;  4WPC A;  2YKT A;  3OK8 A;  2D1L A;  1X03 A;  3G9G A;  4NSW A;  3ACO A;  2RAJ A;  3M3W A;  3DYT A;  4I1Q A;  4FZS A;  1Y2O A;  3QE6 A;  2EFK A;  3Q84 A;  3QNI A;  4H8S A;  2FIC A;  1I4T A;  4ATM A;  5C5B A;  3SOG A;  1I49 A;  2Z0V A;  1I4L A;  3SYV A;  1WDZ A;  4NQI A;  3CAZ A;  2X3W A;  2RAK A;  1ZWW A;  2Z0O A;  1I4D A;  3ABH A;  3LLL A;  2RAI A; 
#chains in the Genus database with same CATH topology
 1OAO A;  4WPE A;  2QFF A;  3CZS A;  3I2W A;  4E81 A;  5TKY A;  3I39 X;  4JWE A;  3BVT A;  4AVM A;  3DX0 A;  2F7Q A;  4R5L A;  2MI7 A;  1UPX A;  3O3M B;  2X3W A;  3LLL A;  4JNF A;  2YIA A;  3T49 A;  1GNL A;  3EJQ A;  4PO2 A;  4HR1 B;  4EZS A;  4F01 A;  2YI9 A;  3BVX A;  2PMR A;  3BVV A;  2RAJ A;  3FD9 A;  2F1B A;  4JWD A;  1HTY A;  1TQT A;  1ZWW A;  2F7R A;  3T46 A;  3UIT A;  4DCN C;  4EZV A;  1SUF A;  2ELB A;  2Q13 A;  4F00 A;  5KBP A;  2JNS A;  2YLL A;  4IWP A;  2EFK A;  4ATM A;  1HWW A;  1SU7 A;  4JNE A;  4HYB A;  2F1A A;  3DDF A;  4EZX A;  1QWN A;  4AZ7 A;  3RPM A;  3ER8 C;  3BLB A;  3BVU A;  4AZ6 A;  3EJP A;  3D2F A;  2D1L A;  1X03 A;  3M3W A;  1Y2O A;  3LVT A;  4FM3 A;  2Z0V A;  3A98 A;  3B53 X;  5FLE X;  3VEB A;  2LXY A;  4JLC A;  4KIK A;  3CKD A;  4NPH A;  2GAF D;  3CV5 A;  4NSW A;  3ACO A;  2ZXQ A;  1JQK A;  3RV0 A;  4AZH A;  1QWU A;  4HY9 A;  4DYL A;  3D52 A;  2WYH A;  2EX3 B;  5E84 A;  2QXL A;  1TQW A;  3EJS A;  2F18 A;  2YL6 A;  4H6H A;  2X5C A;  4I1Q A;  3EJR A;  3D50 A;  4H8S A;  3T47 A;  3BUQ A;  2EWF A;  2Q12 A;  3D4Y A;  4JWC A;  3DX2 A;  4AZC B;  3DX4 A;  2OO2 A;  4B9Q A;  3VKH A;  1E9V A;  2RT6 A;  2LM0 A;  3O3O B;  3I04 A;  4EZO A;  4EZY A;  3CZN A;  5C5B A;  3DX3 A;  3F7W A;  4AZC A;  2YL9 A;  3Q0K A;  3KDR A;  2X3X A;  2Z8Y A;  2KHO A;  4EZN A;  3ERC C;  1O7D B;  1LQ7 A;  2YKT A;  1OA0 A;  2GA9 D;  4AZI A;  3B52 X;  1YWM A;  4EZP A;  4NQI A;  4EZT A;  4IWO A;  2WYI A;  2ALW A;  3QA8 A;  3BUB A;  3DX1 A;  3LMF A;  2YL8 A;  1W9M A;  4IM2 A;  4KIK B;  4AZB A;  4UDX X;  1MJG A;  4UDY X;  2RAK A;  2WIN M;  1SU6 A;  1DKY A;  2OW6 A;  2YIB A;  2OW7 A;  3C7N A;  3DDG A;  3BUD A;  4WPC A;  3I01 A;  3G9G A;  2PY6 A;  2YL5 A;  4FZS A;  3ZED A;  4M0M A;  1I4T A;  2FYV A;  3EJT A;  1WDZ A;  2GF4 A;  3CAZ A;  4EZU A;  3O3N B;  4JL9 A;  4BNE A;  2OBL A;  2Z0N A;  1DKX A;  3ER9 B;  1HXK A;  2YLA A;  1R33 A;  4D8J A;  2JNK A;  4E3C A;  4R5G A;  3DYT A;  3QNJ A;  2NCZ A;  2FIC A;  1TQV A;  1E1D A;  4H6I A;  4IM0 A;  2Z0O A;  3BVW A;  3T48 A;  2D4C A;  2EFL A;  1X04 A;  3QWE A;  4IW0 A;  5C5B B;  3HAH A;  2F7P A;  4JWI A;  4EZW A;  2V0O A;  4IWQ A;  3Q84 A;  3QNI A;  4IM3 A;  3SOG A;  2OZN B;  3ABH A;  3VEA A;  1GNT A;  3RV1 A;  1URU A;  1QX1 A;  3DPO A;  4AKV A;  1R34 A;  3OK8 A;  2N3K A;  4JN4 A;  3QE6 A;  1I4D A;  1I49 A;  3SYV A;  1I4L A;  1R5E A;  3DPP A;  4HR1 A;  2RAI A;  1GN9 A;  2YI8 A;  4FZO A;  2C08 A;  3HAJ A;  2X3V A;  3BUI A;  1U00 A;  4FZP A;  1OA1 A;  3DPQ A;  3CVR A;  4R5I A;  3OWG A;  1O7D C;  3KAW A;  3HAI A;  2ND0 A;  4AZ5 A;  1SU8 A;  2QKW A;  3BUP A;  3D51 A;  1TQS A;  3L3P A;  3EJU A;  3GI7 A;  2ND1 A;  1TQU A;  1E2U A;  2O0I 1;  2OBM A;  2F7O A;  4G6Q A;  4R5K A;  3PLT A;  1PS3 A;  4EZQ A;  3D4Z A;  4EZZ A;  3KAV A;  4AZG A;  2YIV X;  5FIG A;  1ZYL A;  3L3O M;  3T4A G;  1DKZ A;  3D2E A;  3OHX M;  3B51 X;  4R5J A;  4EZR A; 
#chains in the Genus database with same CATH homology
 3HAI A;  2X3X A;  2D4C A;  2Q12 A;  2EFL A;  1X04 A;  3PLT A;  3QWE A;  4DYL A;  4WPE A;  1URU A;  5C5B B;  2C08 A;  3HAH A;  3HAJ A;  2X3V A;  4DCN C;  2ELB A;  4BNE A;  2Q13 A;  3I2W A;  4AKV A;  2Z0N A;  2V0O A;  3Q0K A;  4AVM A;  4WPC A;  2YKT A;  3OK8 A;  2D1L A;  1X03 A;  3G9G A;  4NSW A;  3ACO A;  2RAJ A;  3M3W A;  3DYT A;  4I1Q A;  4FZS A;  1Y2O A;  3QE6 A;  2EFK A;  3Q84 A;  3QNI A;  4H8S A;  2FIC A;  1I4T A;  4ATM A;  5C5B A;  3SOG A;  1I49 A;  2Z0V A;  1I4L A;  3SYV A;  1WDZ A;  4NQI A;  3CAZ A;  2X3W A;  2RAK A;  1ZWW A;  2Z0O A;  1I4D A;  3ABH A;  3LLL A;  2RAI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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