4BNEA

Pacsin2 interacts with membranes and actin-filaments
Total Genus 127
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
127
sequence length
290
structure length
290
Chain Sequence
SDSFWEVGNYKRTVKRIDDGHRLCNDLMNCIHERARIEKVYAQQLTEWAKRWKQLVEKGPQYGTVERAWCAFMSEAEKVSELHLEVKGSLMNEDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRKAQKPWAKKLKEVEAAKKAYHAACKEEKLAISRETNSKADPALNPEQLKKLQDKVERSKQDVLKTKAKYEKSLKELDNATPQYMENMEQVFEQCQQFEEKRLRFFREVLLEVQKHLDLSNVASYKNIYRELEQNIKTADAVEDLRWFRANQGPGMSMNWPQFEDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROT
publication title Direct Interaction of Actin Filaments with F-Bar Protein Pacsin2.
pubmed doi rcsb
source organism Gallus gallus
molecule tags Endocytosis
total genus 127
structure length 290
sequence length 290
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00018 SH3_1 SH3 domain
A PF00611 FCH Fes/CIP4, and EFC/F-BAR homology domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4bneA01
3HAJA 2Z0VA 3M3WA 1WDZA 3CAZA 4DCNC 3HAIA 3OK8A 4FZSA 4NSWA 5C5BA 2Q12A 2FICA 1X03A 3ACOA 3DYTA 3Q0KA 2C08A 3HAHA 1URUA 4AKVA 4I1QA 2X3VA 2Z0OA 3I2WA 4WPCA 3SYVA 2X3XA 1I4LA 1ZWWA 3SOGA 3QNIA 4BNEA 4DYLA 5C5BB 4ATMA 1Y2OA 2D1LA 2RAJA 2ELBA 4NQIA 1X04A 1I4DA 2RAIA 2V0OA 2Z0NA 3LLLA 2EFKA 2X3WA 3QWEA 3PLTA 4AVMA 2EFLA 3QE6A 2YKTA 2RAKA 3G9GA 1I49A 2D4CA 1I4TA 3ABHA 4WPEA 4H8SA 3Q84A 2Q13A
chains in the Genus database with same CATH superfamily
3B53X 4DCNC 4F00A 2YIVX 1R34A 2X3XA 4UDYX 4R5JA 3T48A 4BNEA 4DYLA 2EX3B 3DDFA 1OA1A 2YLLA 1W9MA 1WDZA 4JLCA 3C7NA 3OWGA 1PS3A 3D50A 4H6IA 3DX4A 3D2EA 4M0MA 2F7RA 3RV0A 3DPOA 3DPPA 2KHOA 2WINM 3HAJA 2Z0VA 3D52A 2ZXQA 3CKDA 3I2WA 3SYVA 4EZUA 1R5EA 3EJSA 4EZWA 4NQIA 1TQUA 4JWIA 2Z0NA 4HR1B 3BVWA 3D4YA 1TQSA 2QFFA 3Q84A 3M3WA 2O0I1 4EZVA 2FICA 2OW6A 1OAOA 2QXLA 4AKVA 2X3VA 3QNJA 4WPCA 3O3MB 2NCZA 5C5BB 4D8JA 1SU6A 4AVMA 2Z8YA 2D4CA 2GA9D 1GNTA 1SU8A 1ZYLA 4KIKB 1E2UA 3OK8A 2QKWA 1GN9A 3Q0KA 3HAHA 2OBMA 4AZIA 3KAVA 2WYIA 1ZWWA 3BUQA 4EZTA 3CV5A 2PY6A 2RAJA 3DX0A 1X04A 3T46A 3QWEA 4NPHA 1LQ7A 2F7OA 4JNEA 4H8SA 1O7DB 3ZEDA 2RAIA 4EZZA 2EWFA 1R33A 2GAFD 3UITA 1SUFA 2C08A 4HR1A 3BUDA 3SOGA 2MI7A 1Y2OA 1O7DC 2ELBA 4EZXA 3T47A 1I49A 3ABHA 4PO2A 3BUIA 3D4ZA 3I04A 4IW0A 2Q12A 2FYVA 4I1QA 3OHXM 3LMFA 2WYHA 3QA8A 2D1LA 1YWMA 4AZBA 2V0OA 4E3CA 2F1AA 3QE6A 4R5IA 4WPEA 3BVUA 3ER9B 3F7WA 1QX1A 4AZ7A 4FZOA 4R5GA 1E9VA 4B9QA 2F18A 3VEBA 1U00A 4HY9A 2F1BA 3L3OM 2ND1A 2OW7A 2YKTA 2RAKA 4AZGA 1I4TA 2YL8A 2Q13A 2YI9A 4F01A 1E1DA 3D2FA 1TQTA 3DX2A 4EZOA 4R5LA 1TQWA 3O3OB 1JQKA 3CZNA 4FZPA 4EZQA 3BVTA 3EJPA 2F7PA 4JWCA 4AZ5A 3FD9A 4IWOA 3DX3A 4FZSA 3ACOA 4HYBA 3RPMA 2YIBA 2JNKA 3BUPA 1QWUA 2GF4A 3PLTA 3EJUA 4JL9A 3B51X 3CAZA 3HAIA 3BVXA 1MJGA 1X03A 2F7QA 4IM3A 2ALWA 2LM0A 3BUBA 2OO2A 4FM3A 4IWPA 2EFKA 1HTYA 2YLAA 2X3WA 4EZRA 3BVVA 2YL6A 3I39X 5E84A 3A98A 4JNFA 2YL5A 5C5BA 4JWEA 3DYTA 3EJTA 1URUA 2OBLA 4AZHA 3VEAA 3EJRA 1I4DA 5TKYA 4KIKA 3LVTA 4AZCB 1QWNA 2ND0A 2LXYA 5KBPA 3RV1A 4IM2A 2YL9A 4JWDA 4JN4A 2N3KA 3CVRA 3KDRA 2YIAA 5FLEX 5FIGA 3VKHA 3B52X 4E81A 4IM0A 4EZNA 1HXKA 3DDGA 2YI8A 1DKZA 4R5KA 1GNLA 3I01A 4EZPA 3ERCC 2Z0OA 2PMRA 3L3PA 4IWQA 4EZSA 3QNIA 2RT6A 3EJQA 4ATMA 4AZCA 1DKXA 3LLLA 3ER8C 3G9GA 3CZSA 4G6QA 3KAWA 3DPQA 1OA0A 4NSWA 1UPXA 1DKYA 1HWWA 3GI7A 2JNSA 3T49A 4AZ6A 3DX1A 1SU7A 4H6HA 1TQVA 1I4LA 3D51A 3BLBA 3T4AG 2OZNB 4EZYA 2X5CA 2EFLA 4UDXX 3O3NB
chains in the Genus database with same CATH topology
3HAJA 2Z0VA 3M3WA 1WDZA 3CAZA 4DCNC 3HAIA 3OK8A 4FZSA 4NSWA 5C5BA 2Q12A 2FICA 1X03A 3ACOA 3DYTA 3Q0KA 2C08A 3HAHA 1URUA 4AKVA 4I1QA 2X3VA 2Z0OA 3I2WA 4WPCA 3SYVA 2X3XA 1I4LA 1ZWWA 3SOGA 3QNIA 4BNEA 4DYLA 5C5BB 4ATMA 1Y2OA 2D1LA 2RAJA 2ELBA 4NQIA 1X04A 1I4DA 2RAIA 2V0OA 2Z0NA 3LLLA 2EFKA 2X3WA 3QWEA 3PLTA 4AVMA 2EFLA 3QE6A 2YKTA 2RAKA 3G9GA 1I49A 2D4CA 1I4TA 3ABHA 4WPEA 4H8SA 3Q84A 2Q13A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HAJ A;  2Z0V A;  3M3W A;  1WDZ A;  3CAZ A;  4DCN C;  3HAI A;  3OK8 A;  4FZS A;  4NSW A;  5C5B A;  2Q12 A;  2FIC A;  1X03 A;  3ACO A;  3DYT A;  3Q0K A;  2C08 A;  3HAH A;  1URU A;  4AKV A;  4I1Q A;  2X3V A;  2Z0O A;  3I2W A;  4WPC A;  3SYV A;  2X3X A;  1I4L A;  1ZWW A;  3SOG A;  3QNI A;  4BNE A;  4DYL A;  5C5B B;  4ATM A;  1Y2O A;  2D1L A;  2RAJ A;  2ELB A;  4NQI A;  1X04 A;  1I4D A;  2RAI A;  2V0O A;  2Z0N A;  3LLL A;  2EFK A;  2X3W A;  3QWE A;  3PLT A;  4AVM A;  2EFL A;  3QE6 A;  2YKT A;  2RAK A;  3G9G A;  1I49 A;  2D4C A;  1I4T A;  3ABH A;  4WPE A;  4H8S A;  3Q84 A;  2Q13 A; 
#chains in the Genus database with same CATH topology
 3B53 X;  4DCN C;  4F00 A;  2YIV X;  1R34 A;  2X3X A;  4UDY X;  4R5J A;  3T48 A;  4BNE A;  4DYL A;  2EX3 B;  3DDF A;  1OA1 A;  2YLL A;  1W9M A;  1WDZ A;  4JLC A;  3C7N A;  3OWG A;  1PS3 A;  3D50 A;  4H6I A;  3DX4 A;  3D2E A;  4M0M A;  2F7R A;  3RV0 A;  3DPO A;  3DPP A;  2KHO A;  2WIN M;  3HAJ A;  2Z0V A;  3D52 A;  2ZXQ A;  3CKD A;  3I2W A;  3SYV A;  4EZU A;  1R5E A;  3EJS A;  4EZW A;  4NQI A;  1TQU A;  4JWI A;  2Z0N A;  4HR1 B;  3BVW A;  3D4Y A;  1TQS A;  2QFF A;  3Q84 A;  3M3W A;  2O0I 1;  4EZV A;  2FIC A;  2OW6 A;  1OAO A;  2QXL A;  4AKV A;  2X3V A;  3QNJ A;  4WPC A;  3O3M B;  2NCZ A;  5C5B B;  4D8J A;  1SU6 A;  4AVM A;  2Z8Y A;  2D4C A;  2GA9 D;  1GNT A;  1SU8 A;  1ZYL A;  4KIK B;  1E2U A;  3OK8 A;  2QKW A;  1GN9 A;  3Q0K A;  3HAH A;  2OBM A;  4AZI A;  3KAV A;  2WYI A;  1ZWW A;  3BUQ A;  4EZT A;  3CV5 A;  2PY6 A;  2RAJ A;  3DX0 A;  1X04 A;  3T46 A;  3QWE A;  4NPH A;  1LQ7 A;  2F7O A;  4JNE A;  4H8S A;  1O7D B;  3ZED A;  2RAI A;  4EZZ A;  2EWF A;  1R33 A;  2GAF D;  3UIT A;  1SUF A;  2C08 A;  4HR1 A;  3BUD A;  3SOG A;  2MI7 A;  1Y2O A;  1O7D C;  2ELB A;  4EZX A;  3T47 A;  1I49 A;  3ABH A;  4PO2 A;  3BUI A;  3D4Z A;  3I04 A;  4IW0 A;  2Q12 A;  2FYV A;  4I1Q A;  3OHX M;  3LMF A;  2WYH A;  3QA8 A;  2D1L A;  1YWM A;  4AZB A;  2V0O A;  4E3C A;  2F1A A;  3QE6 A;  4R5I A;  4WPE A;  3BVU A;  3ER9 B;  3F7W A;  1QX1 A;  4AZ7 A;  4FZO A;  4R5G A;  1E9V A;  4B9Q A;  2F18 A;  3VEB A;  1U00 A;  4HY9 A;  2F1B A;  3L3O M;  2ND1 A;  2OW7 A;  2YKT A;  2RAK A;  4AZG A;  1I4T A;  2YL8 A;  2Q13 A;  2YI9 A;  4F01 A;  1E1D A;  3D2F A;  1TQT A;  3DX2 A;  4EZO A;  4R5L A;  1TQW A;  3O3O B;  1JQK A;  3CZN A;  4FZP A;  4EZQ A;  3BVT A;  3EJP A;  2F7P A;  4JWC A;  4AZ5 A;  3FD9 A;  4IWO A;  3DX3 A;  4FZS A;  3ACO A;  4HYB A;  3RPM A;  2YIB A;  2JNK A;  3BUP A;  1QWU A;  2GF4 A;  3PLT A;  3EJU A;  4JL9 A;  3B51 X;  3CAZ A;  3HAI A;  3BVX A;  1MJG A;  1X03 A;  2F7Q A;  4IM3 A;  2ALW A;  2LM0 A;  3BUB A;  2OO2 A;  4FM3 A;  4IWP A;  2EFK A;  1HTY A;  2YLA A;  2X3W A;  4EZR A;  3BVV A;  2YL6 A;  3I39 X;  5E84 A;  3A98 A;  4JNF A;  2YL5 A;  5C5B A;  4JWE A;  3DYT A;  3EJT A;  1URU A;  2OBL A;  4AZH A;  3VEA A;  3EJR A;  1I4D A;  5TKY A;  4KIK A;  3LVT A;  4AZC B;  1QWN A;  2ND0 A;  2LXY A;  5KBP A;  3RV1 A;  4IM2 A;  2YL9 A;  4JWD A;  4JN4 A;  2N3K A;  3CVR A;  3KDR A;  2YIA A;  5FLE X;  5FIG A;  3VKH A;  3B52 X;  4E81 A;  4IM0 A;  4EZN A;  1HXK A;  3DDG A;  2YI8 A;  1DKZ A;  4R5K A;  1GNL A;  3I01 A;  4EZP A;  3ERC C;  2Z0O A;  2PMR A;  3L3P A;  4IWQ A;  4EZS A;  3QNI A;  2RT6 A;  3EJQ A;  4ATM A;  4AZC A;  1DKX A;  3LLL A;  3ER8 C;  3G9G A;  3CZS A;  4G6Q A;  3KAW A;  3DPQ A;  1OA0 A;  4NSW A;  1UPX A;  1DKY A;  1HWW A;  3GI7 A;  2JNS A;  3T49 A;  4AZ6 A;  3DX1 A;  1SU7 A;  4H6H A;  1TQV A;  1I4L A;  3D51 A;  3BLB A;  3T4A G;  2OZN B;  4EZY A;  2X5C A;  2EFL A;  4UDX X;  3O3N B; 
#chains in the Genus database with same CATH homology
 3HAJ A;  2Z0V A;  3M3W A;  1WDZ A;  3CAZ A;  4DCN C;  3HAI A;  3OK8 A;  4FZS A;  4NSW A;  5C5B A;  2Q12 A;  2FIC A;  1X03 A;  3ACO A;  3DYT A;  3Q0K A;  2C08 A;  3HAH A;  1URU A;  4AKV A;  4I1Q A;  2X3V A;  2Z0O A;  3I2W A;  4WPC A;  3SYV A;  2X3X A;  1I4L A;  1ZWW A;  3SOG A;  3QNI A;  4BNE A;  4DYL A;  5C5B B;  4ATM A;  1Y2O A;  2D1L A;  2RAJ A;  2ELB A;  4NQI A;  1X04 A;  1I4D A;  2RAI A;  2V0O A;  2Z0N A;  3LLL A;  2EFK A;  2X3W A;  3QWE A;  3PLT A;  4AVM A;  2EFL A;  3QE6 A;  2YKT A;  2RAK A;  3G9G A;  1I49 A;  2D4C A;  1I4T A;  3ABH A;  4WPE A;  4H8S A;  3Q84 A;  2Q13 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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