4BPWA

Crystal structure of human primase bound to utp
Total Genus 120
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
120
sequence length
407
structure length
382
Chain Sequence
FDPTELPELLKLYYRRLFPYSQYYRWLNYGGVIKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQAANPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESWDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNPWLEWEIMLQYCFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAIRTRDYKKTSLAPYVKVFEHFLENLDKSRKGEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of Human Primase Reveal Design of Nucleotide Elongation Site and Mode of Pol Alpha Tethering
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords DNA PRIMASE SMALL SUBUNIT
total genus 120
structure length 382
sequence length 407
chains with identical sequence C
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01896 DNA_primase_S DNA primase small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.920.30 Alpha Beta Alpha-Beta Complex DNA primase, PRIM domain DNA primase, PRIM domain 4bpwA00
4LIKA 4MHQA 2FAOA 4MM2A 4BPUA 4LILA 4BPXA 1ZT2A 4RR2A 4LIMA 2FARA 2FAQA 5EXRA 4BPWA
chains in the Genus database with same CATH superfamily
4LIKA 4MHQA 2FAOA 4MM2A 4BPUA 2ATZA 4LILA 4BPXA 1ZT2A 4RR2A 4LIMA 1V34A 4BPWA 2FARA 2FAQA 5EXRA 1G71A 1V33A
chains in the Genus database with same CATH topology
4LIKA 4MHQA 2FAOA 4MM2A 4BPUA 4LILA 4BPXA 1ZT2A 4RR2A 4LIMA 1V34A 4BPWA 2FARA 2FAQA 5EXRA 1G71A 1V33A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LIK A;  4MHQ A;  2FAO A;  4MM2 A;  4BPU A;  4LIL A;  4BPX A;  1ZT2 A;  4RR2 A;  4LIM A;  2FAR A;  2FAQ A;  5EXR A;  4BPW A; 
#chains in the Genus database with same CATH topology
 4LIK A;  4MHQ A;  2FAO A;  4MM2 A;  4BPU A;  2ATZ A;  4LIL A;  4BPX A;  1ZT2 A;  4RR2 A;  4LIM A;  1V34 A;  4BPW A;  2FAR A;  2FAQ A;  5EXR A;  1G71 A;  1V33 A; 
#chains in the Genus database with same CATH homology
 4LIK A;  4MHQ A;  2FAO A;  4MM2 A;  4BPU A;  4LIL A;  4BPX A;  1ZT2 A;  4RR2 A;  4LIM A;  1V34 A;  4BPW A;  2FAR A;  2FAQ A;  5EXR A;  1G71 A;  1V33 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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