4C12A

X-ray crystal structure of staphylococcus aureus mure with udp-murnac- ala-glu-lys and adp
Total Genus 177
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
177
sequence length
493
structure length
492
Chain Sequence
MDASTLFKKVKVKRVLGSLEQQIDDITTDSRTAREGSIFVASVGYTVDSHKFCQNVADQGCKLVVVNKEQSLPANVTQVVVPDTLRVASILAHTLYDYPSHQLVTFGVTGTNGKTSIATMIHLIQRKLQKNSAYLGTNGFQINETKTKGANTTPETVSLTKKIKEAVDAGAESMTLEVSSHGLVLGRLRGVEFDVAIFSNLTQDHLDFHGTMEAYGHASLLFSQLGEDLSKEKYVVLNNDDSFSEYLRTVTPYEVFSYGIDEEAQFMAKNIQESLQGVSFDFVTPFGTYPVKSPYVGKFNISNIMAAMIAVWSKGTSLETIIKAVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNKLIDAVQPFVKQKLIFLVGMAGERDLTKTPEMGRVACRADYVIFTPDNPANDDPKMLTAELAKGATHQNYIEFDDRAEGIKHAIDIAEPGDTVVLASKGREPYQIMPGHIKVPHRDDLIGLEAAYKKFGGGPVD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Specificity Determinants for Lysine Incorporation in Staphylococcus Aureus Peptidoglycan as Revealed by the Structure of a Mure Enzyme Ternary Complex.
pubmed doi rcsb
source organism Staphylococcus aureus
molecule tags Ligase
molecule keywords UDP-N-ACETYLMURAMOYL-L-ALANYL-D-GLUTAMATE--L-LYSINE LIGASE
total genus 177
structure length 492
sequence length 493
ec nomenclature ec 6.3.2.7: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase.
pdb deposition date 2013-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01225 Mur_ligase Mur ligase family, catalytic domain
A PF02875 Mur_ligase_C Mur ligase family, glutamate ligase domain
A PF08245 Mur_ligase_M Mur ligase middle domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1190.10 Alpha Beta 3-Layer(aba) Sandwich UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase Mur-like, catalytic domain 4c12A02
3.40.1390.10 Alpha Beta 3-Layer(aba) Sandwich Udp-n-acetylmuramoylalanyl-d-glutamate--2,6- Diaminopimelate Ligase; Chain: A, domain 1 MurE/MurF, N-terminal domain 4c12A01
3.90.190.20 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Mur ligase, C-terminal domain 4c12A03
4C12A 5A5EA 2VTDA 4CVMA 2IU9A 1E8CA 3PMOA 2JFHA 1W78A 1J6UA 1GG4A 2JFFA 3N2AA 2IUAA 4IHGA 1UAGA 4HV4A 2AM2A 5A5FA 4IHFA 2AM1A 3QCZA 4ZIYA 1FGSA 4C13A 1GQYA 2GCAA 4BUCA 4BUBA 4IHHA 2F00A 3EH0A 4E79A 1P31A 3MVNA 1O5ZA 2WJPA 1W7KA 3EAGA 2VTEA 3ZL8A 3HN7A 3ZM5A 2VORA 2GCBA 2X5OA 2XJAA 2Y68A 3LK7A 3PYZA 1E0DA 2Y1OA 4CVKA 3ZM6A 2GC6A 2UAGA 1EEHA 1JBWA 2IU8A 1P3DA 1JBVA 2XPCA 2VOSA 2WTZA 4QF5A 3UAGA 2JFGA 1GQQA 2UUPA 2UUOA 3NRSA 4UAGA 4CVLA 2GC5A 2Y67A 4QDIA 4E75A 2Y66A
chains in the Genus database with same CATH superfamily
1XXPA 4S1IB 2H04A 3CQDA 4Y14A 4B04A 2B4PA 1BX4A 4N08A 2B3OA 2HC2A 2BGDA 5BZXA 3UQDA 4EUMA 3NL3A 1ZCKA 2CM2A 1MKPA 1U25A 1TZ3A 4DU5A 1M3GA 1VI9A 3QKPA 5K9WA 1VHRA 4E79A 3EAXA 1O5ZA 3OTXA 1ESJA 3MMJA 5LXQB 1KNXA 3EB1A 3L31A 2HC1A 3BLUA 4NWGA 2I5BA 5BUGA 1GWZA 3F9AA 5KA0A 1EKQA 2AZRA 4NWFA 5M43A 5BX1A 3DRWA 5IBMA 1OHDA 3RSGA 1ZZWA 1YPTA 4UAGA 3V0HA 1KYHA 1EENA 3EMUA 3O4UA 4QUNA 1RKDA 3Q92A 4GM6A 4K93A 2OUDA 2IMGA 1Q6JA 1P15A 1T49A 2J16A 3QCIA 3QCDA 1RFUA 5EYNA 3RU2A 2AJRA 4N09A 4ICZA 1G7FA 4XDAA 1LARA 1ONYA 2M3VA 3EAGA 3RTAA 3RQXA 2QDPA 4GS0A 2B4UA 5KABA 2VORA 3SMEA 5EHRA 3VAQA 1E0DA 2A9YA 2Y1OA 4XF7A 4R0TA 2BGEA 5KACA 3MOWA 1C83A 4AZ1A 3I7ZA 1YTNA 1PTTA 4I8NA 3B1NA 1PTUA 4KAHA 4E8ZA 3UQEA 1ONZA 1XBOA 3RQ5A 3RTGA 2CM7A 2AA0A 2H4KA 2NT7A 4DGPA 3WSFA 1PTYA 3W4SA 2R3EA 2HW1A 4X8FA 3OLRA 4WJMA 4HV4A 2QBSA 1V19A 4O1LA 3WSEA 1NNYA 2AM1A 1U24A 3ZV2A 5BYCA 2NZ6A 4ZIYA 1OEVA 3F9BA 2QCJA 2Q47A 4LCAA 1Q1MA 1JLNA 3ZL8A 4NNDA 3F41A 1RXDA 3EZZA 1PA9A 2E0TA 4HJQA 4ZRTA 3RTCA 2BV5A 5KA7A 2BZLA 1JBVA 4QF5A 3RPHA 2CNFA 4WOHA 2UUPA 3RQ6A 2FJNA 2GC5A 5KA8A 3HYOA 5A5EA 4CVMA 3QCGA 5B6AA 3S4EA 4Y2EA 1NO6A 4IWGA 1AAXA 3QCJA 5CGEA 2I3UA 1PXHA 1NWLA 5AWXA 3B3LA 3RRBA 2B49A 1GQTA 2VEUA 3HJ6A 3ZMPA 2H02A 1NWEA 4K8CA 3U96A 1C85A 2GC6A 4QAPA 3AWGA 1LYVA 5K22A 3NL6A 5K25A 2G6ZA 2A3KA 4PVVA 5BYEA 3BLTA 4WU2A 4S0GA 3B1RA 3CM3A 1U26A 3B1OA 1FPRA 2HLZA 3ZS7A 5KADA 2VARA 3I3YA 3RTBA 3SR9A 1J6UA 1WRMA 2H03A 5K23A 2JGVA 2QCVA 4KYRA 2GWOA 2I42A 5CGAA 1VK4A 2F6VA 2QBRA 1L8KA 3IN1A 4QBWA 1YWFA 2ABSA 2JJDA 3MBHA 5K9VA 3LOOA 4RI4A 2RF6A 2DDOA 3BRHA 4E3AA 2DDMA 2CM3A 4EBUA 2QDMA 1OEOX 1XXVA 1YTSA 3RM5A 2CNGA 2FYWA 1YFOA 2I6PA 2F46A 4DGXA 4C12A 3K5WA 2I3RA 2FJMA 2WGPA 3V0IA 2B4OA 5KA9A 2NV5A 1UAGA 3S3FA 5A5FA 1BZJA 4GRYA 4LC4A 2FV7A 4UBEA 4RH5A 5C41A 3H49A 3RY7A 4IHHA 1JXHA 2F00A 1T48A 1XRIA 3MBJA 1OEUA 4S1MA 2F70A 4Z6BA 1LHRA 2CMCA 3LHXA 4GE6A 1LIOA 1LIIA 3LJSA 4ZI4A 1V1AA 3PYZA 3EEQA 3GBUA 3A5KA 2C7SA 2ABQA 3UAGA 1G1GA 1RK2A 2UUOA 4QDIA 2F6FA 3FHYA 3RT7A 1G4US 1GFYA 3K9EA 1RFTA 4LBGA 1G4WR 3RT9A 1RFVA 1PYNA 2R3BA 3GO6A 2I6MA 3WSGA 1YGRA 3EU0A 3KEUA 2PBNA 3RPZA 3CWEA 1RKSA 5IBSA 1QZ0A 2I4EA 5TRWA 3QCNA 3RRJA 2AWDA 2VEVA 3UMOA 2I6JA 2DCNA 4C5NA 4D3QA 3PZSA 2I1YA 1YZ4A 3UQ9A 4E84A 3BM8A 1P3DA 2VOSA 4U7XA 4NYHA 5HDEA 1T4JA 4GFUA 1LIJA 1NMOA 2HB1A 3IQ0A 2AFBA 2CMAA 3AWEA 4JMKA 1FPZA 4RKKA 2I6OA 3BF5A 1OEMX 3WSIA 1C84A 3ZM3A 1FGSA 4HJPA 4B8RA 1ECVA 2VEWA 2WJPA 1D5RA 2VTEA 5C3ZA 4K9CA 4EOHA 3NBWA 3B1QA 3QCFA 1PTVA 3ZM6A 2RBCA 3KTNA 4KALA 1SUGA 2XPCA 2WTZA 3Q1YA 3D44A 3NRSA 4E8YA 4BPCA 2HXPA 2H4GA 4WTYA 3V0GA 2ESBA 4XF6A 2IU9A 5F0ZA 1V1BA 4ERCA 5KAAA 2F02A 3RZ2A 4JMJA 4QBEA 2QBQA 3ZMQA 3D1QA 3NM3A 1V3AA 1YGJA 1JF7A 4BUCA 4E69A 2F6TA 2B4SA 4QUMA 4HRFA 1P31A 2CMBA 4RHGA 3QCMA 2I6BA 5BYDA 4KYQA 1QXKA 3NMEA 4R30A 2J17A 1I9TA 3ZM2A 1ZCLA 1EEHA 4KADA 3QA2A 1C3QA 1FQ1A 1G1HA 4PVGA 3RSFA 3V0JA 3IBQA 3RRFA 4E75A 3RGOA 2I6AA 4GE5A 3RREA 2PT0A 2F6WA 2JFHA 4JBCA 4IHGA 3DZVA 1EKKA 2CNIA 1DGMA 4C13A 3S3HA 1J4XA 2F71A 3H74A 2OZ5A 4RI5A 2Y2FA 4ZN5A 5C3YA 3HICA 2HNQA 3S3EA 1OHCA 2J16B 1NL9A 1RKAA 2GCBA 2V78A 2YXUA 5KA3A 1KAKA 3V0EA 4JKSA 3V0FA 3WSDA 3HPDA 2ZN7A 3V0DA 3NM1A 2YYBA 2F7KA 2JFGA 5CM5A 2PKMA 2VTDA 4K8TA 2AHSA 3QAIA 4IHFA 2I75A 3O4SA 3RSSA 5EHPA 2HQQA 4C5LA 2C46A 4C5JA 2GJTA 3LKIA 4GRZA 5BZZA 2A8BA 4JJPA 1L2LA 1Q6SA 1C88A 2CNEA 2HCMA 2PA5A 2XTBA 3PS5A 2XJAA 2Y68A 4S1IA 3O3LA 3QCKA 4OHLA 1RPMA 2PKFA 3H2XA 3LJ8A 1EEOA 5K24A 4RH9A 2I4HA 1LHPA 4LBXA 1UA4A 2BIJA 2Y67A 2I6IA 3QCBA 4GWFA 5KA1A 2QEPA 2CNHA 2A9ZA 4KBEA 4JNBA 1ESQA 1GG4A 3MOZA 1NZ7A 2IUAA 3L2BA 2AM2A 3GXHA 3RSQA 1UB0A 2G59A 3BGKA 3KZHA 3AWFA 2ZMMA 4D3RA 5J8RA 1WCHA 5EY7A 3N1CA 3RQ2A 1KO7A 2Q05A 3MVNA 1W7KA 3RQHA 5COJA 2PKKA 3UQ6A 4C5MA 5F11A 4YWRA 1R6HA 2PSZA 2PKNA 3F81A 4OHDA 4C5KA 3B1PA 2B07A 2Y96A 1V1SA 1YGKA 4TVVA 3RS8A 3RO4A 5C40A 4OHHA 3M4UA 1U2XA 1Q6PA 3RTEA 2NLKA 3D42A 5TQIA 2IOJA 3N2AA 2JFFA 3GO7A 3NBVA 4K9IA 2C4EA 3UBOA 2OOQA 3N0AA 1I57A 1XM2A 2P4DA 1YN9A 4QAHA 3QKQA 1GQYA 2GCAA 1YGUA 1WAXA 3RO1A 2NWHA 4OHIA 3RTDA 4H1OA 3ZM0A 2QHPA 3EWMA 2DDWA 2JG5A 1OESA 2F6ZA 4YR8B 4BJOA 3I80A 4GFVA 3NL5A 3D9CA 1YTWA 2NT2A 3IKHA 1JXIA 3NL2A 4WU3A 2QBPA 2HY3A 4XCKA 1W78A 2VEXA 2PI7A 3B7OA 2HVLA 2P6XA 2NTAA 3ZM1A 4K8PA 2YXTA 2CM8A 1LQFA 4BUBA 2OC3A 4DC3A 4RDDA 2MBCA 3O5XA 3QCEA 1OHEA 3ZM5A 3RQQA 3S3KA 2H4VA 4IKCA 2HNPA 2UAGA 1TZ6A 1C86A 2GP0A 1JBWA 2IU8A 1GC5A 3IH0A 1GQQA 4PYHA 1C87A 5MMZB 4H34A 1YHJA 4IWMA 2Y66A 2F6YA 3A5JA 4E8WA 1WYEA 4JKUA 4OHEA 1TYYA 2CJZA 4D3PA 2QCTA 1Q6TA 3WSHA 2JG1A 3RGQA 2FH7A 3QCZA 4YL5A 2Q5RA 3GXGA 4S1HA 1Q6MA 4MBBA 1OETA 1NMPA 3NC9A 3EH0A 3RS9A 3I36A 4NX8A 2YDUA 3QCCA 4GE2A 4CVKA 1PA1A 3O4TA 3IE7A 1BZCA 3S4OA 3NCAA 3RU3A 3F99A 1Q6NA 2QDCA 2I5XA 1VM7A 1G7GA 1PH0A 1X24A 5GTJA 3VASA 4K8KA 4CVLA 4KANA 5I6VA 2DXPA 1E8CA 3PMOA 4B8SA 4YAAA 3UMPA 3OMHA 2I4GA 2PQ5A 2C49A 3D1OA 2AX3A 1A5YA 4O1GA 2AJPA 2AB8A 2VEYA 1BZHA 5BYFA 5KA2A 3HN7A 1KAVA 1I9SA 3PL2A 4KI9A 3LK7A 2X5OA 3JULA 4EN4A 1ZC0A 4R0SA 3NC2A 2SHPA 5KA4A 1G1FA 3QCLA 2CFVA 3D1HA 3KD6A 3QCHA 3RQ8A 3FHXA 1L8GA 4J51A 1LIKA 1TD2A 2R0BA
chains in the Genus database with same CATH topology
4C12A 5A5EA 2VTDA 4CVMA 2IU9A 1E8CA 3PMOA 2JFHA 1W78A 1J6UA 1GG4A 2JFFA 3N2AA 2IUAA 4IHGA 1UAGA 4HV4A 2AM2A 5A5FA 4IHFA 2AM1A 3QCZA 4ZIYA 1FGSA 4C13A 1GQYA 2GCAA 4BUCA 4BUBA 4IHHA 2F00A 3EH0A 4E79A 1P31A 3MVNA 1O5ZA 2WJPA 1W7KA 3EAGA 2VTEA 3ZL8A 3HN7A 3ZM5A 2VORA 2GCBA 2X5OA 2XJAA 2Y68A 3LK7A 3PYZA 1E0DA 2Y1OA 4CVKA 3ZM6A 2GC6A 2UAGA 1EEHA 1JBWA 2IU8A 1P3DA 1JBVA 2XPCA 2VOSA 2WTZA 4QF5A 3UAGA 2JFGA 1GQQA 2UUPA 2UUOA 3NRSA 4UAGA 4CVLA 2GC5A 2Y67A 4QDIA 4E75A 2Y66A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C12 A;  5A5E A;  2VTD A;  4CVM A;  2IU9 A;  1E8C A;  3PMO A;  2JFH A;  1W78 A;  1J6U A;  1GG4 A;  2JFF A;  3N2A A;  2IUA A;  4IHG A;  1UAG A;  4HV4 A;  2AM2 A;  5A5F A;  4IHF A;  2AM1 A;  3QCZ A;  4ZIY A;  1FGS A;  4C13 A;  1GQY A;  2GCA A;  4BUC A;  4BUB A;  4IHH A;  2F00 A;  3EH0 A;  4E79 A;  1P31 A;  3MVN A;  1O5Z A;  2WJP A;  1W7K A;  3EAG A;  2VTE A;  3ZL8 A;  3HN7 A;  3ZM5 A;  2VOR A;  2GCB A;  2X5O A;  2XJA A;  2Y68 A;  3LK7 A;  3PYZ A;  1E0D A;  2Y1O A;  4CVK A;  3ZM6 A;  2GC6 A;  2UAG A;  1EEH A;  1JBW A;  2IU8 A;  1P3D A;  1JBV A;  2XPC A;  2VOS A;  2WTZ A;  4QF5 A;  3UAG A;  2JFG A;  1GQQ A;  2UUP A;  2UUO A;  3NRS A;  4UAG A;  4CVL A;  2GC5 A;  2Y67 A;  4QDI A;  4E75 A;  2Y66 A; 
#chains in the Genus database with same CATH topology
 1XXP A;  4S1I B;  2H04 A;  3CQD A;  4Y14 A;  4B04 A;  2B4P A;  1BX4 A;  4N08 A;  2B3O A;  2HC2 A;  2BGD A;  5BZX A;  3UQD A;  4EUM A;  3NL3 A;  1ZCK A;  2CM2 A;  1MKP A;  1U25 A;  1TZ3 A;  4DU5 A;  1M3G A;  1VI9 A;  3QKP A;  5K9W A;  1VHR A;  4E79 A;  3EAX A;  1O5Z A;  3OTX A;  1ESJ A;  3MMJ A;  5LXQ B;  1KNX A;  3EB1 A;  3L31 A;  2HC1 A;  3BLU A;  4NWG A;  2I5B A;  5BUG A;  1GWZ A;  3F9A A;  5KA0 A;  1EKQ A;  2AZR A;  4NWF A;  5M43 A;  5BX1 A;  3DRW A;  5IBM A;  1OHD A;  3RSG A;  1ZZW A;  1YPT A;  4UAG A;  3V0H A;  1KYH A;  1EEN A;  3EMU A;  3O4U A;  4QUN A;  1RKD A;  3Q92 A;  4GM6 A;  4K93 A;  2OUD A;  2IMG A;  1Q6J A;  1P15 A;  1T49 A;  2J16 A;  3QCI A;  3QCD A;  1RFU A;  5EYN A;  3RU2 A;  2AJR A;  4N09 A;  4ICZ A;  1G7F A;  4XDA A;  1LAR A;  1ONY A;  2M3V A;  3EAG A;  3RTA A;  3RQX A;  2QDP A;  4GS0 A;  2B4U A;  5KAB A;  2VOR A;  3SME A;  5EHR A;  3VAQ A;  1E0D A;  2A9Y A;  2Y1O A;  4XF7 A;  4R0T A;  2BGE A;  5KAC A;  3MOW A;  1C83 A;  4AZ1 A;  3I7Z A;  1YTN A;  1PTT A;  4I8N A;  3B1N A;  1PTU A;  4KAH A;  4E8Z A;  3UQE A;  1ONZ A;  1XBO A;  3RQ5 A;  3RTG A;  2CM7 A;  2AA0 A;  2H4K A;  2NT7 A;  4DGP A;  3WSF A;  1PTY A;  3W4S A;  2R3E A;  2HW1 A;  4X8F A;  3OLR A;  4WJM A;  4HV4 A;  2QBS A;  1V19 A;  4O1L A;  3WSE A;  1NNY A;  2AM1 A;  1U24 A;  3ZV2 A;  5BYC A;  2NZ6 A;  4ZIY A;  1OEV A;  3F9B A;  2QCJ A;  2Q47 A;  4LCA A;  1Q1M A;  1JLN A;  3ZL8 A;  4NND A;  3F41 A;  1RXD A;  3EZZ A;  1PA9 A;  2E0T A;  4HJQ A;  4ZRT A;  3RTC A;  2BV5 A;  5KA7 A;  2BZL A;  1JBV A;  4QF5 A;  3RPH A;  2CNF A;  4WOH A;  2UUP A;  3RQ6 A;  2FJN A;  2GC5 A;  5KA8 A;  3HYO A;  5A5E A;  4CVM A;  3QCG A;  5B6A A;  3S4E A;  4Y2E A;  1NO6 A;  4IWG A;  1AAX A;  3QCJ A;  5CGE A;  2I3U A;  1PXH A;  1NWL A;  5AWX A;  3B3L A;  3RRB A;  2B49 A;  1GQT A;  2VEU A;  3HJ6 A;  3ZMP A;  2H02 A;  1NWE A;  4K8C A;  3U96 A;  1C85 A;  2GC6 A;  4QAP A;  3AWG A;  1LYV A;  5K22 A;  3NL6 A;  5K25 A;  2G6Z A;  2A3K A;  4PVV A;  5BYE A;  3BLT A;  4WU2 A;  4S0G A;  3B1R A;  3CM3 A;  1U26 A;  3B1O A;  1FPR A;  2HLZ A;  3ZS7 A;  5KAD A;  2VAR A;  3I3Y A;  3RTB A;  3SR9 A;  1J6U A;  1WRM A;  2H03 A;  5K23 A;  2JGV A;  2QCV A;  4KYR A;  2GWO A;  2I42 A;  5CGA A;  1VK4 A;  2F6V A;  2QBR A;  1L8K A;  3IN1 A;  4QBW A;  1YWF A;  2ABS A;  2JJD A;  3MBH A;  5K9V A;  3LOO A;  4RI4 A;  2RF6 A;  2DDO A;  3BRH A;  4E3A A;  2DDM A;  2CM3 A;  4EBU A;  2QDM A;  1OEO X;  1XXV A;  1YTS A;  3RM5 A;  2CNG A;  2FYW A;  1YFO A;  2I6P A;  2F46 A;  4DGX A;  4C12 A;  3K5W A;  2I3R A;  2FJM A;  2WGP A;  3V0I A;  2B4O A;  5KA9 A;  2NV5 A;  1UAG A;  3S3F A;  5A5F A;  1BZJ A;  4GRY A;  4LC4 A;  2FV7 A;  4UBE A;  4RH5 A;  5C41 A;  3H49 A;  3RY7 A;  4IHH A;  1JXH A;  2F00 A;  1T48 A;  1XRI A;  3MBJ A;  1OEU A;  4S1M A;  2F70 A;  4Z6B A;  1LHR A;  2CMC A;  3LHX A;  4GE6 A;  1LIO A;  1LII A;  3LJS A;  4ZI4 A;  1V1A A;  3PYZ A;  3EEQ A;  3GBU A;  3A5K A;  2C7S A;  2ABQ A;  3UAG A;  1G1G A;  1RK2 A;  2UUO A;  4QDI A;  2F6F A;  3FHY A;  3RT7 A;  1G4U S;  1GFY A;  3K9E A;  1RFT A;  4LBG A;  1G4W R;  3RT9 A;  1RFV A;  1PYN A;  2R3B A;  3GO6 A;  2I6M A;  3WSG A;  1YGR A;  3EU0 A;  3KEU A;  2PBN A;  3RPZ A;  3CWE A;  1RKS A;  5IBS A;  1QZ0 A;  2I4E A;  5TRW A;  3QCN A;  3RRJ A;  2AWD A;  2VEV A;  3UMO A;  2I6J A;  2DCN A;  4C5N A;  4D3Q A;  3PZS A;  2I1Y A;  1YZ4 A;  3UQ9 A;  4E84 A;  3BM8 A;  1P3D A;  2VOS A;  4U7X A;  4NYH A;  5HDE A;  1T4J A;  4GFU A;  1LIJ A;  1NMO A;  2HB1 A;  3IQ0 A;  2AFB A;  2CMA A;  3AWE A;  4JMK A;  1FPZ A;  4RKK A;  2I6O A;  3BF5 A;  1OEM X;  3WSI A;  1C84 A;  3ZM3 A;  1FGS A;  4HJP A;  4B8R A;  1ECV A;  2VEW A;  2WJP A;  1D5R A;  2VTE A;  5C3Z A;  4K9C A;  4EOH A;  3NBW A;  3B1Q A;  3QCF A;  1PTV A;  3ZM6 A;  2RBC A;  3KTN A;  4KAL A;  1SUG A;  2XPC A;  2WTZ A;  3Q1Y A;  3D44 A;  3NRS A;  4E8Y A;  4BPC A;  2HXP A;  2H4G A;  4WTY A;  3V0G A;  2ESB A;  4XF6 A;  2IU9 A;  5F0Z A;  1V1B A;  4ERC A;  5KAA A;  2F02 A;  3RZ2 A;  4JMJ A;  4QBE A;  2QBQ A;  3ZMQ A;  3D1Q A;  3NM3 A;  1V3A A;  1YGJ A;  1JF7 A;  4BUC A;  4E69 A;  2F6T A;  2B4S A;  4QUM A;  4HRF A;  1P31 A;  2CMB A;  4RHG A;  3QCM A;  2I6B A;  5BYD A;  4KYQ A;  1QXK A;  3NME A;  4R30 A;  2J17 A;  1I9T A;  3ZM2 A;  1ZCL A;  1EEH A;  4KAD A;  3QA2 A;  1C3Q A;  1FQ1 A;  1G1H A;  4PVG A;  3RSF A;  3V0J A;  3IBQ A;  3RRF A;  4E75 A;  3RGO A;  2I6A A;  4GE5 A;  3RRE A;  2PT0 A;  2F6W A;  2JFH A;  4JBC A;  4IHG A;  3DZV A;  1EKK A;  2CNI A;  1DGM A;  4C13 A;  3S3H A;  1J4X A;  2F71 A;  3H74 A;  2OZ5 A;  4RI5 A;  2Y2F A;  4ZN5 A;  5C3Y A;  3HIC A;  2HNQ A;  3S3E A;  1OHC A;  2J16 B;  1NL9 A;  1RKA A;  2GCB A;  2V78 A;  2YXU A;  5KA3 A;  1KAK A;  3V0E A;  4JKS A;  3V0F A;  3WSD A;  3HPD A;  2ZN7 A;  3V0D A;  3NM1 A;  2YYB A;  2F7K A;  2JFG A;  5CM5 A;  2PKM A;  2VTD A;  4K8T A;  2AHS A;  3QAI A;  4IHF A;  2I75 A;  3O4S A;  3RSS A;  5EHP A;  2HQQ A;  4C5L A;  2C46 A;  4C5J A;  2GJT A;  3LKI A;  4GRZ A;  5BZZ A;  2A8B A;  4JJP A;  1L2L A;  1Q6S A;  1C88 A;  2CNE A;  2HCM A;  2PA5 A;  2XTB A;  3PS5 A;  2XJA A;  2Y68 A;  4S1I A;  3O3L A;  3QCK A;  4OHL A;  1RPM A;  2PKF A;  3H2X A;  3LJ8 A;  1EEO A;  5K24 A;  4RH9 A;  2I4H A;  1LHP A;  4LBX A;  1UA4 A;  2BIJ A;  2Y67 A;  2I6I A;  3QCB A;  4GWF A;  5KA1 A;  2QEP A;  2CNH A;  2A9Z A;  4KBE A;  4JNB A;  1ESQ A;  1GG4 A;  3MOZ A;  1NZ7 A;  2IUA A;  3L2B A;  2AM2 A;  3GXH A;  3RSQ A;  1UB0 A;  2G59 A;  3BGK A;  3KZH A;  3AWF A;  2ZMM A;  4D3R A;  5J8R A;  1WCH A;  5EY7 A;  3N1C A;  3RQ2 A;  1KO7 A;  2Q05 A;  3MVN A;  1W7K A;  3RQH A;  5COJ A;  2PKK A;  3UQ6 A;  4C5M A;  5F11 A;  4YWR A;  1R6H A;  2PSZ A;  2PKN A;  3F81 A;  4OHD A;  4C5K A;  3B1P A;  2B07 A;  2Y96 A;  1V1S A;  1YGK A;  4TVV A;  3RS8 A;  3RO4 A;  5C40 A;  4OHH A;  3M4U A;  1U2X A;  1Q6P A;  3RTE A;  2NLK A;  3D42 A;  5TQI A;  2IOJ A;  3N2A A;  2JFF A;  3GO7 A;  3NBV A;  4K9I A;  2C4E A;  3UBO A;  2OOQ A;  3N0A A;  1I57 A;  1XM2 A;  2P4D A;  1YN9 A;  4QAH A;  3QKQ A;  1GQY A;  2GCA A;  1YGU A;  1WAX A;  3RO1 A;  2NWH A;  4OHI A;  3RTD A;  4H1O A;  3ZM0 A;  2QHP A;  3EWM A;  2DDW A;  2JG5 A;  1OES A;  2F6Z A;  4YR8 B;  4BJO A;  3I80 A;  4GFV A;  3NL5 A;  3D9C A;  1YTW A;  2NT2 A;  3IKH A;  1JXI A;  3NL2 A;  4WU3 A;  2QBP A;  2HY3 A;  4XCK A;  1W78 A;  2VEX A;  2PI7 A;  3B7O A;  2HVL A;  2P6X A;  2NTA A;  3ZM1 A;  4K8P A;  2YXT A;  2CM8 A;  1LQF A;  4BUB A;  2OC3 A;  4DC3 A;  4RDD A;  2MBC A;  3O5X A;  3QCE A;  1OHE A;  3ZM5 A;  3RQQ A;  3S3K A;  2H4V A;  4IKC A;  2HNP A;  2UAG A;  1TZ6 A;  1C86 A;  2GP0 A;  1JBW A;  2IU8 A;  1GC5 A;  3IH0 A;  1GQQ A;  4PYH A;  1C87 A;  5MMZ B;  4H34 A;  1YHJ A;  4IWM A;  2Y66 A;  2F6Y A;  3A5J A;  4E8W A;  1WYE A;  4JKU A;  4OHE A;  1TYY A;  2CJZ A;  4D3P A;  2QCT A;  1Q6T A;  3WSH A;  2JG1 A;  3RGQ A;  2FH7 A;  3QCZ A;  4YL5 A;  2Q5R A;  3GXG A;  4S1H A;  1Q6M A;  4MBB A;  1OET A;  1NMP A;  3NC9 A;  3EH0 A;  3RS9 A;  3I36 A;  4NX8 A;  2YDU A;  3QCC A;  4GE2 A;  4CVK A;  1PA1 A;  3O4T A;  3IE7 A;  1BZC A;  3S4O A;  3NCA A;  3RU3 A;  3F99 A;  1Q6N A;  2QDC A;  2I5X A;  1VM7 A;  1G7G A;  1PH0 A;  1X24 A;  5GTJ A;  3VAS A;  4K8K A;  4CVL A;  4KAN A;  5I6V A;  2DXP A;  1E8C A;  3PMO A;  4B8S A;  4YAA A;  3UMP A;  3OMH A;  2I4G A;  2PQ5 A;  2C49 A;  3D1O A;  2AX3 A;  1A5Y A;  4O1G A;  2AJP A;  2AB8 A;  2VEY A;  1BZH A;  5BYF A;  5KA2 A;  3HN7 A;  1KAV A;  1I9S A;  3PL2 A;  4KI9 A;  3LK7 A;  2X5O A;  3JUL A;  4EN4 A;  1ZC0 A;  4R0S A;  3NC2 A;  2SHP A;  5KA4 A;  1G1F A;  3QCL A;  2CFV A;  3D1H A;  3KD6 A;  3QCH A;  3RQ8 A;  3FHX A;  1L8G A;  4J51 A;  1LIK A;  1TD2 A;  2R0B A; 
#chains in the Genus database with same CATH homology
 4C12 A;  5A5E A;  2VTD A;  4CVM A;  2IU9 A;  1E8C A;  3PMO A;  2JFH A;  1W78 A;  1J6U A;  1GG4 A;  2JFF A;  3N2A A;  2IUA A;  4IHG A;  1UAG A;  4HV4 A;  2AM2 A;  5A5F A;  4IHF A;  2AM1 A;  3QCZ A;  4ZIY A;  1FGS A;  4C13 A;  1GQY A;  2GCA A;  4BUC A;  4BUB A;  4IHH A;  2F00 A;  3EH0 A;  4E79 A;  1P31 A;  3MVN A;  1O5Z A;  2WJP A;  1W7K A;  3EAG A;  2VTE A;  3ZL8 A;  3HN7 A;  3ZM5 A;  2VOR A;  2GCB A;  2X5O A;  2XJA A;  2Y68 A;  3LK7 A;  3PYZ A;  1E0D A;  2Y1O A;  4CVK A;  3ZM6 A;  2GC6 A;  2UAG A;  1EEH A;  1JBW A;  2IU8 A;  1P3D A;  1JBV A;  2XPC A;  2VOS A;  2WTZ A;  4QF5 A;  3UAG A;  2JFG A;  1GQQ A;  2UUP A;  2UUO A;  3NRS A;  4UAG A;  4CVL A;  2GC5 A;  2Y67 A;  4QDI A;  4E75 A;  2Y66 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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