4C1YB

Crystal structure of fucose binding lectin from aspergillus fumigatus (afl) in complex with b-methylfucoside
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
314
structure length
314
Chain Sequence
STPGAQQVLFRTGIAAVNSTNHLRVYFQDVYGSIRESLYEGSWANGTEKNVIGNAKLGSPVAATSKELKHIRVYTLTEGNTLQEFAYDSGTGWYNGGLGGAKFQVAPYSCIAAVFLAGTDALQLRIYAQKPDNTIQEYMWNGDGWKEGTNLGGALPGTGIGATSFRYTDYNGPSIRIWFQTDDLKLVQRAYDPHKGWYPDLVTIFDRAPPRTAIAATSFGAGNSSIYMRIYFVNSDNTIWQVCWDHGKGYHDKGTITPVIQGSEVAIISWGSFANNGPDLRLYFQNGTYISAVSEWVWNRAHGSQLGRSALPPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into Aspergillus Fumigatus Lectin Specificity: Afl Binding Sites are Functionally Non-Equivalent.
pubmed doi rcsb
molecule keywords FUCOSE-SPECIFIC LECTIN FLEA
molecule tags Sugar binding protein
source organism Aspergillus fumigatus
total genus 72
structure length 314
sequence length 314
chains with identical sequence C, D
ec nomenclature
pdb deposition date 2013-08-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF07938 Fungal_lectin Fungal fucose-specific lectin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.70 Mainly Beta 6 Propeller Neuraminidase Fucose-specific lectin 4c1yB00
4C1YB 4D52A 1IUCA 4CSDA 4UOUA 4D52C 4AHAA 4AGIA 5EO7A 5H47A 4AH4A 4D52B 5EO8A 4C1YA 4D4UA 1OFZA 4AGTA 1IUBA
chains in the Genus database with same CATH superfamily
3SALA 3K39A 4L7DA 1W0OA 1NCBN 4MWYA 1NCAN 2WOZA 4J9TA 4K1JA 5EO7A 4NCSA 1E8UA 3FVZA 4FP3A 1X2JA 3K3AA 4B7MA 4FVKA 1B9TA 1IVEA 4YW3A 1Z50A 1Z4WA 1B9VA 1NN2A 4IQKA 4UOUA 2P4OA 4I00A 3UC1A 1MS5A 1RWLA 5FNRA 2YDTA 3ZGCA 4DGRA 1N1YA 1MR5A 4M3MA 5FNSA 4CPLA 1IVBA 3TI6A 2YA6A 1NMAN 2W20A 4HHQA 4NC5A 1V0EA 1NNCA 4ZGCA 1W8NA 4L7CA 3K38A 1VCUA 4FPGA 1USXA 2ZB6A 1S18A 2IASA 2IAOA 4H52A 4GZSA 4GZOA 1Z4YA 1V3BA 3O4PA 1QBIA 1MWEA 5HUGA 1N6DA 3B7EA 4FPOB 4DG6A 3K37A 4HZWA 3TI4A 1V04A 1MZ6A 3GVJA 2IAUA 1EUSA 2IAPA 2F28A 3Q6PA 2VVZA 4XYXA 4YW5A 4AGTA 4MZAA 1MS8A 2VK7A 3WW9A 1MZ5A 3O9JA 1E8TA 1W20A 3TIBA 2YA5A 4WEGA 1L7FA 2HT5A 4ZLRA 2BZDA 2F12A 1WP5A 4XJUA 4HW6A 1SLIA 3SOVA 1NSDA 2HTQA 4G3NA 1F8DA 4CPZA 4MWWA 4QNPA 2F10A 1H6LA 1W0PA 3V65B 2XCYA 5HUKA 3LI5A 3T1EA 3DR2A 4MX0A 2GVXA 3ZGDA 3HLHA 2HTUA 1SO7A 4D52A 1KITA 4XIKA 1DILA 3A71A 4HZVA 2F24A 2VSMA 1K32A 3G4HA 3S94A 3TIAA 5GX5A 5D9BA 1NPEA 4YZ4A 4K1HA 4L7BA 4GDJA 4Q6KA 4UF7A 2F13A 2GHSA 5D9CA 4CSDA 2QWEA 2HQSA 1NMCA 1N6FA 4XIOA 3H72A 4XHXA 4FZHA 2F29A 2HTRA 1C9UA 3SLIA 4R40A 1V0FA 2VSKA 4MJVA 1IVCA 5JYYA 3BYCA 1NSCA 4GNBA 5HX0A 4M4NA 5B2CA 1WCSA 3WN7A 4WA4A 3SANA 2HTYA 1A14N 1SNTA 4XMAA 1Q7FA 4FOYA 1W21A 2C4AA 4QN6A 3PJQA 4GN8A 2GVWA 1MS4A 4IMBA 4FPHA 1A4GA 4KS5A 5GX2A 2FPCA 3L6VA 7NN9A 4M4VA 4ZY3A 2VPJA 1QLGA 4GZQA 4MZEA 3KGGA 4AH4A 2VWDA 1NNBA 1BJIA 4CPYA 4K1IA 4GDIA 2ZWAA 2F26A 2RKCA 2W5NA 2W8BA 2YDPA 1IVGA 2W5OA 3ALXA 2VW2A 4XJAA 3S2KA 2SIMA 4FJ6A 2IAVA 4D52C 4FPLA 1CRUA 1F8CA 4O5SA 1L7HA 2IVZA 3NSSA 4H53A 1Z4ZA 2FPBA 1WCQA 3TICA 2HU0A 3ADEA 1MS0A 4MWLA 1U6DX 4K3YA 4QN7A 3II7A 3Q6TA 3G4EA 1EUTA 4B7RA 4GJTA 4MWVA 2FHRA 2VK5A 1CQ1A 3NN9A 2HTVA 1OFZA 3S8VA 3TC9A 3V1SA 4YW1A 3WWAA 4KS1A 5NN9A 2DSOA 4JMLA 1ZI0A 1CRZA 1Z4XA 2QWHA 3VNGA 3SOQA 4GNAA 3S8ZA 3HLIA 2QWDA 4HZXA 3SREA 3I1CA 5FNUA 4XJRA 5H47A 4M4UA 2A75A 4B7QA 4D4UA 2QWGA 2DG1A 2AEPA 2XZKA 2F11A 1NMBN 5FNQA 2OJHA 3AMRA 4C1YB 3GVLA 3VNHA 2AH2A 4FPCA 4XMBA 1INYA 4GZPA 2GVVA 3JU4A 4CHBA 4FP2A 3DASA 2QWKA 3SOBB 1SLLA 4PWZA 2POOA 2FLUX 5B2DA 2HTWA 1V0ZA 4X4AA 1N1SA 2GVUA 4AHAA 1MS9A 1RWIA 1F8BA 1INXA 1XOEA 3CKZA 5FWWA 1IVFA 4XJQA 4CPOA 3CYEA 1XOGA 4MWXA 1INFA 4CPMA 1MS1A 4QN3A 4QN5A 4X6KA 5FNTA 1INVA 3TI5A 1N6EA 2VW1A 4MWQA 4IFNX 3A72A 2VK6A 4HZZA 6NN9A 4X47A 2XZJA 5M1ZA 5GX3A 3GVKA 1IUBA 2B8HA 2IAWA 4XHBA 4YY8A 3E5ZA 4XJ9A 2FP8A 3B69A 4KS4A 3A9GA 1E1AA 4YZ1A 2SLIA 2QWBA 1V3DA 2H2NA 4XOGA 2C4LA 4HHOA 1IJQA 3INBA 3D12A 3SRGA 3A9HA 5EX7A 5F9TA 2HT7A 2VAQA 5HUNA 1N1TA 1VCJA 4YZ2A 5GX1A 4N1BA 3H6JA 5EO8A 4GZWA 3P5BL 1V3EA 4IFLX 4MJUA 2QWIA 1S0IA 2ISMA 2BF6A 3OPZA 4QN4A 4HZYA 3W09A 4XILA 4YZ5A 3CL2A 2G8SA 2F27A 2HU4A 1C5KA 3BEQA 4YW2A 1MS3A 1NSBA 5F72C 2XZIA 4KS2A 1F8EA 4FQ4A 2W38A 2ZW9A 4CPNA 4FPYA 5D9DA 3IAXA 1INGA 4FPJA 4IYGA 4ASCA 4GZTA 2YA8A 4D8SA 4IN4A 2DYHA 4JF7A 3H73A 4XMIA 4MC7A 1ZGKA 4GEZA 1EUUA 2ZB5A 4FPFA 4YW4A 1E8VA 4MWJA 4YZ3A 1S1DA 1PJXA 1B9SA 2QWCA 1V3CA 1INHA 2CMLA 4NN9A 5HUMA 4FOQA 4GN7A 4XE9A 2VW0A 3V64C 4WEFA 3O9KA 1IVDA 4SLIA 4FOWA 4BBWA 4WA3A 1L7GA 3Q6KA 3U0SA 4AGIA 4D52B 2XN4A 4MWRA 3LI3A 3K36A 3ALWA 4B7JA 1NNAA 4Q1UA 3WDZA 4K1KA 1USRA 1POOA 3AMSA 2QE8A 4WA5A 3H71A 1W1XA 1Z4VA 3SILA 5GTQA 1NCCN 4GN9A 2X9MA 3NO0A 4CH9A 1NCDN 5CGJA 4GNCA 4FOVA 3HRPA 4KS3A 4XJZA 5FZNA 3CL0A 4XJ8A 4O5TA 2HT8A 2BATA 4X49A 2Z32A 2JKBA 1IUCA 4HIZA 2IATA 4IFJA 4FPEA 2F0ZA 2IAXA 4FPKA 4C1YA 2F25A 4GZXA 2QWJA 2DG0A 2YA4A 1S0JA 2ZZKA 3TI3A 3KYAA 4B7NA 5FZJA 1DIMA 1V2IA 2IARA 2AEQA 2QWAA 4GB1A 5GX4A 3FW0A 1A4QA 3TI8A 4MWUA 2H2UA 2V91A 2QWFA 2FP9A 2AGSA 1EURA 1SUUA 2YA7A 4A0PA 2BERA 1X2RA 1W8OA 3D11A 1N7DA 1INWA 2IAQA 4XJWA 1N1VA 3LI4A 1CVMA 2SILA 2W8BB
chains in the Genus database with same CATH topology
4C1YB 4D52A 1IUCA 4CSDA 4UOUA 4D52C 4AHAA 4AGIA 5EO7A 5H47A 4AH4A 4D52B 5EO8A 4C1YA 4D4UA 1OFZA 4AGTA 1IUBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C1Y B;  4D52 A;  1IUC A;  4CSD A;  4UOU A;  4D52 C;  4AHA A;  4AGI A;  5EO7 A;  5H47 A;  4AH4 A;  4D52 B;  5EO8 A;  4C1Y A;  4D4U A;  1OFZ A;  4AGT A;  1IUB A; 
#chains in the Genus database with same CATH topology
 3SAL A;  3K39 A;  4L7D A;  1W0O A;  1NCB N;  4MWY A;  1NCA N;  2WOZ A;  4J9T A;  4K1J A;  5EO7 A;  4NCS A;  1E8U A;  3FVZ A;  4FP3 A;  1X2J A;  3K3A A;  4B7M A;  4FVK A;  1B9T A;  1IVE A;  4YW3 A;  1Z50 A;  1Z4W A;  1B9V A;  1NN2 A;  4IQK A;  4UOU A;  2P4O A;  4I00 A;  3UC1 A;  1MS5 A;  1RWL A;  5FNR A;  2YDT A;  3ZGC A;  4DGR A;  1N1Y A;  1MR5 A;  4M3M A;  5FNS A;  4CPL A;  1IVB A;  3TI6 A;  2YA6 A;  1NMA N;  2W20 A;  4HHQ A;  4NC5 A;  1V0E A;  1NNC A;  4ZGC A;  1W8N A;  4L7C A;  3K38 A;  1VCU A;  4FPG A;  1USX A;  2ZB6 A;  1S18 A;  2IAS A;  2IAO A;  4H52 A;  4GZS A;  4GZO A;  1Z4Y A;  1V3B A;  3O4P A;  1QBI A;  1MWE A;  5HUG A;  1N6D A;  3B7E A;  4FPO B;  4DG6 A;  3K37 A;  4HZW A;  3TI4 A;  1V04 A;  1MZ6 A;  3GVJ A;  2IAU A;  1EUS A;  2IAP A;  2F28 A;  3Q6P A;  2VVZ A;  4XYX A;  4YW5 A;  4AGT A;  4MZA A;  1MS8 A;  2VK7 A;  3WW9 A;  1MZ5 A;  3O9J A;  1E8T A;  1W20 A;  3TIB A;  2YA5 A;  4WEG A;  1L7F A;  2HT5 A;  4ZLR A;  2BZD A;  2F12 A;  1WP5 A;  4XJU A;  4HW6 A;  1SLI A;  3SOV A;  1NSD A;  2HTQ A;  4G3N A;  1F8D A;  4CPZ A;  4MWW A;  4QNP A;  2F10 A;  1H6L A;  1W0P A;  3V65 B;  2XCY A;  5HUK A;  3LI5 A;  3T1E A;  3DR2 A;  4MX0 A;  2GVX A;  3ZGD A;  3HLH A;  2HTU A;  1SO7 A;  4D52 A;  1KIT A;  4XIK A;  1DIL A;  3A71 A;  4HZV A;  2F24 A;  2VSM A;  1K32 A;  3G4H A;  3S94 A;  3TIA A;  5GX5 A;  5D9B A;  1NPE A;  4YZ4 A;  4K1H A;  4L7B A;  4GDJ A;  4Q6K A;  4UF7 A;  2F13 A;  2GHS A;  5D9C A;  4CSD A;  2QWE A;  2HQS A;  1NMC A;  1N6F A;  4XIO A;  3H72 A;  4XHX A;  4FZH A;  2F29 A;  2HTR A;  1C9U A;  3SLI A;  4R40 A;  1V0F A;  2VSK A;  4MJV A;  1IVC A;  5JYY A;  3BYC A;  1NSC A;  4GNB A;  5HX0 A;  4M4N A;  5B2C A;  1WCS A;  3WN7 A;  4WA4 A;  3SAN A;  2HTY A;  1A14 N;  1SNT A;  4XMA A;  1Q7F A;  4FOY A;  1W21 A;  2C4A A;  4QN6 A;  3PJQ A;  4GN8 A;  2GVW A;  1MS4 A;  4IMB A;  4FPH A;  1A4G A;  4KS5 A;  5GX2 A;  2FPC A;  3L6V A;  7NN9 A;  4M4V A;  4ZY3 A;  2VPJ A;  1QLG A;  4GZQ A;  4MZE A;  3KGG A;  4AH4 A;  2VWD A;  1NNB A;  1BJI A;  4CPY A;  4K1I A;  4GDI A;  2ZWA A;  2F26 A;  2RKC A;  2W5N A;  2W8B A;  2YDP A;  1IVG A;  2W5O A;  3ALX A;  2VW2 A;  4XJA A;  3S2K A;  2SIM A;  4FJ6 A;  2IAV A;  4D52 C;  4FPL A;  1CRU A;  1F8C A;  4O5S A;  1L7H A;  2IVZ A;  3NSS A;  4H53 A;  1Z4Z A;  2FPB A;  1WCQ A;  3TIC A;  2HU0 A;  3ADE A;  1MS0 A;  4MWL A;  1U6D X;  4K3Y A;  4QN7 A;  3II7 A;  3Q6T A;  3G4E A;  1EUT A;  4B7R A;  4GJT A;  4MWV A;  2FHR A;  2VK5 A;  1CQ1 A;  3NN9 A;  2HTV A;  1OFZ A;  3S8V A;  3TC9 A;  3V1S A;  4YW1 A;  3WWA A;  4KS1 A;  5NN9 A;  2DSO A;  4JML A;  1ZI0 A;  1CRZ A;  1Z4X A;  2QWH A;  3VNG A;  3SOQ A;  4GNA A;  3S8Z A;  3HLI A;  2QWD A;  4HZX A;  3SRE A;  3I1C A;  5FNU A;  4XJR A;  5H47 A;  4M4U A;  2A75 A;  4B7Q A;  4D4U A;  2QWG A;  2DG1 A;  2AEP A;  2XZK A;  2F11 A;  1NMB N;  5FNQ A;  2OJH A;  3AMR A;  4C1Y B;  3GVL A;  3VNH A;  2AH2 A;  4FPC A;  4XMB A;  1INY A;  4GZP A;  2GVV A;  3JU4 A;  4CHB A;  4FP2 A;  3DAS A;  2QWK A;  3SOB B;  1SLL A;  4PWZ A;  2POO A;  2FLU X;  5B2D A;  2HTW A;  1V0Z A;  4X4A A;  1N1S A;  2GVU A;  4AHA A;  1MS9 A;  1RWI A;  1F8B A;  1INX A;  1XOE A;  3CKZ A;  5FWW A;  1IVF A;  4XJQ A;  4CPO A;  3CYE A;  1XOG A;  4MWX A;  1INF A;  4CPM A;  1MS1 A;  4QN3 A;  4QN5 A;  4X6K A;  5FNT A;  1INV A;  3TI5 A;  1N6E A;  2VW1 A;  4MWQ A;  4IFN X;  3A72 A;  2VK6 A;  4HZZ A;  6NN9 A;  4X47 A;  2XZJ A;  5M1Z A;  5GX3 A;  3GVK A;  1IUB A;  2B8H A;  2IAW A;  4XHB A;  4YY8 A;  3E5Z A;  4XJ9 A;  2FP8 A;  3B69 A;  4KS4 A;  3A9G A;  1E1A A;  4YZ1 A;  2SLI A;  2QWB A;  1V3D A;  2H2N A;  4XOG A;  2C4L A;  4HHO A;  1IJQ A;  3INB A;  3D12 A;  3SRG A;  3A9H A;  5EX7 A;  5F9T A;  2HT7 A;  2VAQ A;  5HUN A;  1N1T A;  1VCJ A;  4YZ2 A;  5GX1 A;  4N1B A;  3H6J A;  5EO8 A;  4GZW A;  3P5B L;  1V3E A;  4IFL X;  4MJU A;  2QWI A;  1S0I A;  2ISM A;  2BF6 A;  3OPZ A;  4QN4 A;  4HZY A;  3W09 A;  4XIL A;  4YZ5 A;  3CL2 A;  2G8S A;  2F27 A;  2HU4 A;  1C5K A;  3BEQ A;  4YW2 A;  1MS3 A;  1NSB A;  5F72 C;  2XZI A;  4KS2 A;  1F8E A;  4FQ4 A;  2W38 A;  2ZW9 A;  4CPN A;  4FPY A;  5D9D A;  3IAX A;  1ING A;  4FPJ A;  4IYG A;  4ASC A;  4GZT A;  2YA8 A;  4D8S A;  4IN4 A;  2DYH A;  4JF7 A;  3H73 A;  4XMI A;  4MC7 A;  1ZGK A;  4GEZ A;  1EUU A;  2ZB5 A;  4FPF A;  4YW4 A;  1E8V A;  4MWJ A;  4YZ3 A;  1S1D A;  1PJX A;  1B9S A;  2QWC A;  1V3C A;  1INH A;  2CML A;  4NN9 A;  5HUM A;  4FOQ A;  4GN7 A;  4XE9 A;  2VW0 A;  3V64 C;  4WEF A;  3O9K A;  1IVD A;  4SLI A;  4FOW A;  4BBW A;  4WA3 A;  1L7G A;  3Q6K A;  3U0S A;  4AGI A;  4D52 B;  2XN4 A;  4MWR A;  3LI3 A;  3K36 A;  3ALW A;  4B7J A;  1NNA A;  4Q1U A;  3WDZ A;  4K1K A;  1USR A;  1POO A;  3AMS A;  2QE8 A;  4WA5 A;  3H71 A;  1W1X A;  1Z4V A;  3SIL A;  5GTQ A;  1NCC N;  4GN9 A;  2X9M A;  3NO0 A;  4CH9 A;  1NCD N;  5CGJ A;  4GNC A;  4FOV A;  3HRP A;  4KS3 A;  4XJZ A;  5FZN A;  3CL0 A;  4XJ8 A;  4O5T A;  2HT8 A;  2BAT A;  4X49 A;  2Z32 A;  2JKB A;  1IUC A;  4HIZ A;  2IAT A;  4IFJ A;  4FPE A;  2F0Z A;  2IAX A;  4FPK A;  4C1Y A;  2F25 A;  4GZX A;  2QWJ A;  2DG0 A;  2YA4 A;  1S0J A;  2ZZK A;  3TI3 A;  3KYA A;  4B7N A;  5FZJ A;  1DIM A;  1V2I A;  2IAR A;  2AEQ A;  2QWA A;  4GB1 A;  5GX4 A;  3FW0 A;  1A4Q A;  3TI8 A;  4MWU A;  2H2U A;  2V91 A;  2QWF A;  2FP9 A;  2AGS A;  1EUR A;  1SUU A;  2YA7 A;  4A0P A;  2BER A;  1X2R A;  1W8O A;  3D11 A;  1N7D A;  1INW A;  2IAQ A;  4XJW A;  1N1V A;  3LI4 A;  1CVM A;  2SIL A;  2W8B B; 
#chains in the Genus database with same CATH homology
 4C1Y B;  4D52 A;  1IUC A;  4CSD A;  4UOU A;  4D52 C;  4AHA A;  4AGI A;  5EO7 A;  5H47 A;  4AH4 A;  4D52 B;  5EO8 A;  4C1Y A;  4D4U A;  1OFZ A;  4AGT A;  1IUB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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