4C2M1

Structure of rna polymerase i at 2.8 a resolution
Total Genus 5
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
5
sequence length
44
structure length
44
Chain Sequence
LKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title RNA Polymerase I Structure and Transcription Regulation.
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4
total genus 5
structure length 44
sequence length 44
chains with identical sequence L
ec nomenclature
pdb deposition date 2013-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
1 PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4c2m100
5M5WL 3RZDL 2VUML 3S1NL 3GTGL 2WB1P 4BY1L 3GTQL 4C3JL 3I4ML 3K7AL 3PO2L 4A3CL 2E2JL 3S1QL 4Y52L 3HOYL 1TWGL 4A3BL 4A93L 5IP7L 1Y1WL 2E2IL 2NVTL 3GTOL 4A3EL 1TWHL 5C44L 3M4OL 2R93L 2R92L 3CQZL 1Y1VL 3GTJL 5M3FL 4A3ML 1K83L 5IYBL 5M5YL 2PMZP 4Y7NL 4A3KL 4A3JL 1SFOL 2R7ZL 3S17L 3M3YL 3S16L 1I50L 5IYDL 5FJ8L 2NVXL 5IP9L 3S1ML 5M5XL 3HOXL 2JA8L 3S2DL 1I6HL 1I3QL 4C3HL 3GTKL 3HOVL 4BBSL 3S1RL 2YU9L 5FLML 3FKIL 2NVYL 1TWFL 3HKZP 1WCML 3HOUL 3GTML 3I4NL 2Y0SP 5IYCL 3RZOL 1TWCL 2WAQP 3S14L 4A3FL 3HOWL 4C3IL 4A3DL 3S2HL 3GTLL 3HOZL 4AYBP 4QIWP 1TWAL 4C2M1 3GTPL 5M3ML 3PO3L 5C3EL 4A3GL 3S15L 4BY7L 3H0GL 2JA7L 2JA6L 4A3LL 2B63L 4A3IL 4BXXL 5C4XL 3H3VM 4BBRL 5C4JL 2JA5L 2NVQL 2E2HL 1R9TL 4X6AL
chains in the Genus database with same CATH superfamily
1R0HA 3RZDL 5GAHc 1IU6A 3K7AL 4A3CL 2E2JL 4JAEA 1QCVA 5AI3A 3PZAA 3J7Y1 1RB9A 3GTOL 3H9CA 1FHMA 3GTJL 3PWFA 2V0EA 2B5ID 3MQKB 2A6HD 4K9FA 3P2AA 5M5YL 2XJPA 1QYBA 3KYUA 2PMZP 4Y7NL 3LNLA 1ODHA 3S17L 3M3YL 1DX8A 5IYDL 3ZG6A 3S1ML 4UY81 1I3QL 1NXGA 4AHWA 1IROA 2V0FA 1R0FA 1S24A 2YU9L 5FLML 2XJVA 3HKZP 2PVEA 3SS2A 5IYCL 2ZIXA 1S2ZA 2JI3A 1JYBA 3S2HL 3RZ6A 8RXNA 4C2M1 1VZIA 1YUXA 1YK4A 2M4VA 3PKIA 1BQ9A 1LKOA 4BY7L 2JA7L 2JA6L 4JADA 4A3IL 5C4XL 3H3VM 2JA5L 2NYDA 1B13A 2NVQL 1BQ8A 2XJRA 2C6AA 5EIOC 5M5WL 4WFN1 1SMMA 3S1NL 3GTGL 4BY1L 3GTQL 2M4YA 4C3JL 1H7VA 4YWLA 3KYXA 3PKJA 1TWGL 4A3BL 5AN9H 2PVXA 4A93L 1YK5A 4AI2A 3A44A 5IP7L 3B08B 5H1Sc 2NVTL 2HR5A 1P7PA 4B8CD 4A3EL 4U671 1SMUA 2GMGA 2R92L 2J9UB 1PZXA 2CKCA 2XJUA 2EY4E 4AR6A 1RYTA 2RDVA 2L0ZA 3K35A 4XXBB 4A3KL 4A3JL 1SFOL 2R7ZL 3FDJA 1VZHA 4AI3A 3S16L 1OWCA 4AHXA 4ZN1B 5M5XL 3VPBE 1PFYA 1RDGA 1E8JA 3HOVL 4C3HL 4E6YA 3GTKL 3S1RL 1OWBA 2NVYL 1R0JA 1TWFL 3B0AB 3RZTA 2K2DA 1SMWA 3LWPB 1BFYA 3PIO1 5AI2A 1VCXA 2O5JD 5GAGc 3S14L 5MF6A 2KN9A 3HOZL 4QIWP 3QQCE 3PO3L 4POGA 5C3EL 2M6OA 3S15L 3NFPI 4AR4A 4JAFA 2XJSA 3HJWB 2B63L 4BXXL 6RXNA 4BBRL 5C4JL 5MFZA 3H97A 1WJVA 2E2HL 4JAGA 2APOB 2CKAA 2C6BA 2PPTA 3J7Z1 2WB1P 2CR8A 2KKDA 3I4ML 2ERSA 5MFPA 3PO2L 3S1QL 4Y52L 1F4LA 3RYGA 1VZGA 4AHZA 1CADA 5DM61 1T9QA 1YUZA 5MLC3 2A68D 2DSXA 1RYQA 4TVMA 1TWHL 3M4OL 2R93L 4V196 3CQZL 4A3ML 2V3BB 5EINC 2MS3A 1K83L 1IRNA 1T9OA 3WWLA 4AR5A 3HAXC 3LPEB 1BRFA 5DM71 7RXNA 2PSMC 5K2ME 1R0GA 4YWMA 3PIP1 1RDVA 5MGNA 1CAAA 3QVDA 1BE7A 3HOXL 1LTLA 1PFWA 4BBSL 1C09A 3GTML 2Y0SP 4XGHA 3RZOL 3H99A 2VL6A 2PYAA 3H9BA 4C3IL 4LHNA 1QQTA 3GTLL 3GTPL 4RXNA 4A3GL 3LWOB 4GS7D 3LWQB 3IU3I 1B2JA 1LKMA 3MPSA 2AYJA 2RFKB 2JI2A 1R9TL 3KYVA 2VUML 5IY0A 2A6ED 2XJTA 3WWNB 3JR7A 3LWRB 4POFA 3HOYL 5JVG1 4LHLA 1Y1WL 2E2IL 3MSUA 2Z3QB 5RXNA 3HJYB 5C44L 1Y1VL 5GADc 5M3FL 2XJQA 2HVYC 4AI0A 4AI1A 5IYBL 1RWDA 2QL0A 1Z92B 3KYWA 1FHHA 2AQCA 1I50L 3KYYA 1IU5A 5FJ8L 3LWVB 2NVXL 1NXEA 5IP9L 2JA8L 4AR3A 3S2DL 1I6HL 5JVH1 2ERJA 1DVBA 1R0IA 3FKIL 3PL5A 1WCML 3HOUL 5GAEc 3I4NL 1B71A 1NNQA 1TWCL 2WAQP 2AUSB 2A69D 4A3FL 1PFUA 2H12A 3HOWL 4A3DL 4AHYA 4ME3A 2Z3RB 4AYBP 1TWAL 1YV1A 5M3ML 1PFVA 2M6PA 1T9PA 1B2OA 2BE5D 3H0GL 4A3LL 1IW7D 1LKPA 4G6BA 3P8BA 1ZRPA 2JI1A 2LCQA 4TPUA 1S30A 4ZN3B 4X6AL
chains in the Genus database with same CATH topology
5M5WL 3RZDL 2VUML 3S1NL 3GTGL 2WB1P 4BY1L 3GTQL 4C3JL 3I4ML 3K7AL 3PO2L 4A3CL 2E2JL 3S1QL 4Y52L 3HOYL 1TWGL 4A3BL 4A93L 5IP7L 1Y1WL 2E2IL 2NVTL 3GTOL 4A3EL 1TWHL 5C44L 3M4OL 2R93L 2R92L 3CQZL 1Y1VL 3GTJL 5M3FL 4A3ML 1K83L 5IYBL 5M5YL 2PMZP 4Y7NL 4A3KL 4A3JL 1SFOL 2R7ZL 3S17L 3M3YL 3S16L 1I50L 5IYDL 5FJ8L 2NVXL 5IP9L 3S1ML 5M5XL 3HOXL 2JA8L 3S2DL 1I6HL 1I3QL 4C3HL 3GTKL 3HOVL 4BBSL 3S1RL 2YU9L 5FLML 3FKIL 2NVYL 1TWFL 3HKZP 1WCML 3HOUL 3GTML 3I4NL 2Y0SP 5IYCL 3RZOL 1TWCL 2WAQP 3S14L 4A3FL 3HOWL 4C3IL 4A3DL 3S2HL 3GTLL 3HOZL 4AYBP 4QIWP 1TWAL 4C2M1 3GTPL 5M3ML 3PO3L 5C3EL 4A3GL 3S15L 4BY7L 3H0GL 2JA7L 2JA6L 4A3LL 2B63L 4A3IL 4BXXL 5C4XL 3H3VM 4BBRL 5C4JL 2JA5L 2NVQL 2E2HL 1R9TL 4X6AL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5M5W L;  3RZD L;  2VUM L;  3S1N L;  3GTG L;  2WB1 P;  4BY1 L;  3GTQ L;  4C3J L;  3I4M L;  3K7A L;  3PO2 L;  4A3C L;  2E2J L;  3S1Q L;  4Y52 L;  3HOY L;  1TWG L;  4A3B L;  4A93 L;  5IP7 L;  1Y1W L;  2E2I L;  2NVT L;  3GTO L;  4A3E L;  1TWH L;  5C44 L;  3M4O L;  2R93 L;  2R92 L;  3CQZ L;  1Y1V L;  3GTJ L;  5M3F L;  4A3M L;  1K83 L;  5IYB L;  5M5Y L;  2PMZ P;  4Y7N L;  4A3K L;  4A3J L;  1SFO L;  2R7Z L;  3S17 L;  3M3Y L;  3S16 L;  1I50 L;  5IYD L;  5FJ8 L;  2NVX L;  5IP9 L;  3S1M L;  5M5X L;  3HOX L;  2JA8 L;  3S2D L;  1I6H L;  1I3Q L;  4C3H L;  3GTK L;  3HOV L;  4BBS L;  3S1R L;  2YU9 L;  5FLM L;  3FKI L;  2NVY L;  1TWF L;  3HKZ P;  1WCM L;  3HOU L;  3GTM L;  3I4N L;  2Y0S P;  5IYC L;  3RZO L;  1TWC L;  2WAQ P;  3S14 L;  4A3F L;  3HOW L;  4C3I L;  4A3D L;  3S2H L;  3GTL L;  3HOZ L;  4AYB P;  4QIW P;  1TWA L;  4C2M 1;  3GTP L;  5M3M L;  3PO3 L;  5C3E L;  4A3G L;  3S15 L;  4BY7 L;  3H0G L;  2JA7 L;  2JA6 L;  4A3L L;  2B63 L;  4A3I L;  4BXX L;  5C4X L;  3H3V M;  4BBR L;  5C4J L;  2JA5 L;  2NVQ L;  2E2H L;  1R9T L;  4X6A L; 
#chains in the Genus database with same CATH topology
 1R0H A;  3RZD L;  5GAH c;  1IU6 A;  3K7A L;  4A3C L;  2E2J L;  4JAE A;  1QCV A;  5AI3 A;  3PZA A;  3J7Y 1;  1RB9 A;  3GTO L;  3H9C A;  1FHM A;  3GTJ L;  3PWF A;  2V0E A;  2B5I D;  3MQK B;  2A6H D;  4K9F A;  3P2A A;  5M5Y L;  2XJP A;  1QYB A;  3KYU A;  2PMZ P;  4Y7N L;  3LNL A;  1ODH A;  3S17 L;  3M3Y L;  1DX8 A;  5IYD L;  3ZG6 A;  3S1M L;  4UY8 1;  1I3Q L;  1NXG A;  4AHW A;  1IRO A;  2V0F A;  1R0F A;  1S24 A;  2YU9 L;  5FLM L;  2XJV A;  3HKZ P;  2PVE A;  3SS2 A;  5IYC L;  2ZIX A;  1S2Z A;  2JI3 A;  1JYB A;  3S2H L;  3RZ6 A;  8RXN A;  4C2M 1;  1VZI A;  1YUX A;  1YK4 A;  2M4V A;  3PKI A;  1BQ9 A;  1LKO A;  4BY7 L;  2JA7 L;  2JA6 L;  4JAD A;  4A3I L;  5C4X L;  3H3V M;  2JA5 L;  2NYD A;  1B13 A;  2NVQ L;  1BQ8 A;  2XJR A;  2C6A A;  5EIO C;  5M5W L;  4WFN 1;  1SMM A;  3S1N L;  3GTG L;  4BY1 L;  3GTQ L;  2M4Y A;  4C3J L;  1H7V A;  4YWL A;  3KYX A;  3PKJ A;  1TWG L;  4A3B L;  5AN9 H;  2PVX A;  4A93 L;  1YK5 A;  4AI2 A;  3A44 A;  5IP7 L;  3B08 B;  5H1S c;  2NVT L;  2HR5 A;  1P7P A;  4B8C D;  4A3E L;  4U67 1;  1SMU A;  2GMG A;  2R92 L;  2J9U B;  1PZX A;  2CKC A;  2XJU A;  2EY4 E;  4AR6 A;  1RYT A;  2RDV A;  2L0Z A;  3K35 A;  4XXB B;  4A3K L;  4A3J L;  1SFO L;  2R7Z L;  3FDJ A;  1VZH A;  4AI3 A;  3S16 L;  1OWC A;  4AHX A;  4ZN1 B;  5M5X L;  3VPB E;  1PFY A;  1RDG A;  1E8J A;  3HOV L;  4C3H L;  4E6Y A;  3GTK L;  3S1R L;  1OWB A;  2NVY L;  1R0J A;  1TWF L;  3B0A B;  3RZT A;  2K2D A;  1SMW A;  3LWP B;  1BFY A;  3PIO 1;  5AI2 A;  1VCX A;  2O5J D;  5GAG c;  3S14 L;  5MF6 A;  2KN9 A;  3HOZ L;  4QIW P;  3QQC E;  3PO3 L;  4POG A;  5C3E L;  2M6O A;  3S15 L;  3NFP I;  4AR4 A;  4JAF A;  2XJS A;  3HJW B;  2B63 L;  4BXX L;  6RXN A;  4BBR L;  5C4J L;  5MFZ A;  3H97 A;  1WJV A;  2E2H L;  4JAG A;  2APO B;  2CKA A;  2C6B A;  2PPT A;  3J7Z 1;  2WB1 P;  2CR8 A;  2KKD A;  3I4M L;  2ERS A;  5MFP A;  3PO2 L;  3S1Q L;  4Y52 L;  1F4L A;  3RYG A;  1VZG A;  4AHZ A;  1CAD A;  5DM6 1;  1T9Q A;  1YUZ A;  5MLC 3;  2A68 D;  2DSX A;  1RYQ A;  4TVM A;  1TWH L;  3M4O L;  2R93 L;  4V19 6;  3CQZ L;  4A3M L;  2V3B B;  5EIN C;  2MS3 A;  1K83 L;  1IRN A;  1T9O A;  3WWL A;  4AR5 A;  3HAX C;  3LPE B;  1BRF A;  5DM7 1;  7RXN A;  2PSM C;  5K2M E;  1R0G A;  4YWM A;  3PIP 1;  1RDV A;  5MGN A;  1CAA A;  3QVD A;  1BE7 A;  3HOX L;  1LTL A;  1PFW A;  4BBS L;  1C09 A;  3GTM L;  2Y0S P;  4XGH A;  3RZO L;  3H99 A;  2VL6 A;  2PYA A;  3H9B A;  4C3I L;  4LHN A;  1QQT A;  3GTL L;  3GTP L;  4RXN A;  4A3G L;  3LWO B;  4GS7 D;  3LWQ B;  3IU3 I;  1B2J A;  1LKM A;  3MPS A;  2AYJ A;  2RFK B;  2JI2 A;  1R9T L;  3KYV A;  2VUM L;  5IY0 A;  2A6E D;  2XJT A;  3WWN B;  3JR7 A;  3LWR B;  4POF A;  3HOY L;  5JVG 1;  4LHL A;  1Y1W L;  2E2I L;  3MSU A;  2Z3Q B;  5RXN A;  3HJY B;  5C44 L;  1Y1V L;  5GAD c;  5M3F L;  2XJQ A;  2HVY C;  4AI0 A;  4AI1 A;  5IYB L;  1RWD A;  2QL0 A;  1Z92 B;  3KYW A;  1FHH A;  2AQC A;  1I50 L;  3KYY A;  1IU5 A;  5FJ8 L;  3LWV B;  2NVX L;  1NXE A;  5IP9 L;  2JA8 L;  4AR3 A;  3S2D L;  1I6H L;  5JVH 1;  2ERJ A;  1DVB A;  1R0I A;  3FKI L;  3PL5 A;  1WCM L;  3HOU L;  5GAE c;  3I4N L;  1B71 A;  1NNQ A;  1TWC L;  2WAQ P;  2AUS B;  2A69 D;  4A3F L;  1PFU A;  2H12 A;  3HOW L;  4A3D L;  4AHY A;  4ME3 A;  2Z3R B;  4AYB P;  1TWA L;  1YV1 A;  5M3M L;  1PFV A;  2M6P A;  1T9P A;  1B2O A;  2BE5 D;  3H0G L;  4A3L L;  1IW7 D;  1LKP A;  4G6B A;  3P8B A;  1ZRP A;  2JI1 A;  2LCQ A;  4TPU A;  1S30 A;  4ZN3 B;  4X6A L; 
#chains in the Genus database with same CATH homology
 5M5W L;  3RZD L;  2VUM L;  3S1N L;  3GTG L;  2WB1 P;  4BY1 L;  3GTQ L;  4C3J L;  3I4M L;  3K7A L;  3PO2 L;  4A3C L;  2E2J L;  3S1Q L;  4Y52 L;  3HOY L;  1TWG L;  4A3B L;  4A93 L;  5IP7 L;  1Y1W L;  2E2I L;  2NVT L;  3GTO L;  4A3E L;  1TWH L;  5C44 L;  3M4O L;  2R93 L;  2R92 L;  3CQZ L;  1Y1V L;  3GTJ L;  5M3F L;  4A3M L;  1K83 L;  5IYB L;  5M5Y L;  2PMZ P;  4Y7N L;  4A3K L;  4A3J L;  1SFO L;  2R7Z L;  3S17 L;  3M3Y L;  3S16 L;  1I50 L;  5IYD L;  5FJ8 L;  2NVX L;  5IP9 L;  3S1M L;  5M5X L;  3HOX L;  2JA8 L;  3S2D L;  1I6H L;  1I3Q L;  4C3H L;  3GTK L;  3HOV L;  4BBS L;  3S1R L;  2YU9 L;  5FLM L;  3FKI L;  2NVY L;  1TWF L;  3HKZ P;  1WCM L;  3HOU L;  3GTM L;  3I4N L;  2Y0S P;  5IYC L;  3RZO L;  1TWC L;  2WAQ P;  3S14 L;  4A3F L;  3HOW L;  4C3I L;  4A3D L;  3S2H L;  3GTL L;  3HOZ L;  4AYB P;  4QIW P;  1TWA L;  4C2M 1;  3GTP L;  5M3M L;  3PO3 L;  5C3E L;  4A3G L;  3S15 L;  4BY7 L;  3H0G L;  2JA7 L;  2JA6 L;  4A3L L;  2B63 L;  4A3I L;  4BXX L;  5C4X L;  3H3V M;  4BBR L;  5C4J L;  2JA5 L;  2NVQ L;  2E2H L;  1R9T L;  4X6A L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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