4C3HL

Structure of 14-subunit rna polymerase i at 3.27 a resolution, crystal form c2-93
Total Genus 2
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
2
sequence length
45
structure length
45
Chain Sequence
TLKYICAECSSKLSLSRTDAVRCKDCGHRILLKARTKRLVQFEAR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA190
publication title Crystal Structure of the 14-Subunit RNA Polymerase I
pubmed doi rcsb
molecule tags Transcription
total genus 2
structure length 45
sequence length 45
ec nomenclature
pdb deposition date 2013-08-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
L PF03604 DNA_RNApol_7kD DNA directed RNA polymerase, 7 kDa subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.20.28.30 Mainly Beta Single Sheet Rubrerythrin, domain 2 RNA polymerase ii, chain L 4c3hL00
2WB1P 5C4JL 3S17L 2JA6L 4A3EL 3S2HL 5IYCL 2B63L 2NVTL 3S1RL 2R92L 3GTLL 1TWGL 3GTJL 4AYBP 4Y7NL 2E2JL 4A3CL 1Y1VL 2PMZP 3S14L 3PO3L 4BY1L 3GTQL 4A3ML 3K7AL 1WCML 5M5XL 2E2IL 2NVYL 2VUML 2YU9L 5FLML 5IYDL 4A3DL 3M3YL 3H0GL 1Y1WL 3CQZL 3S1ML 3RZDL 4BBSL 2NVXL 5C44L 2JA5L 3GTPL 3S1QL 1R9TL 3HOYL 2JA8L 3HOUL 3GTML 2WAQP 1K83L 4QIWP 5C3EL 3H3VM 4A3LL 3HOZL 1TWCL 3S16L 5IP9L 1TWFL 3I4NL 3HOVL 4A3KL 5M5YL 4BY7L 4A3IL 2E2HL 4Y52L 1I50L 5IYBL 1I6HL 3GTOL 4C2M1 4C3JL 5M3ML 1TWHL 3S2DL 4X6AL 5M5WL 4A93L 5FJ8L 4A3BL 4C3IL 1TWAL 3FKIL 3I4ML 4A3FL 3GTGL 4A3JL 3RZOL 3HKZP 2JA7L 3PO2L 2R7ZL 3S1NL 3HOWL 1SFOL 4C3HL 3M4OL 2R93L 3GTKL 2Y0SP 4A3GL 1I3QL 4BBRL 3S15L 5C4XL 4BXXL 5IP7L 3HOXL 2NVQL 5M3FL
chains in the Genus database with same CATH superfamily
3RZTA 2WB1P 3S17L 4A3EL 2PVXA 2A68D 3MPSA 3S1RL 3GTLL 1LKMA 3S14L 3GTQL 3KYVA 4A3ML 1FHMA 3ZG6A 3K7AL 2Z3QB 1LTLA 5AN9H 5FLML 2M4YA 4JAEA 3S1ML 1IW7D 2XJSA 2JA5L 3GTPL 3KYYA 1R9TL 1T9QA 5MFPA 3A44A 1ODHA 1BE7A 1BFYA 2ZIXA 3S16L 1CAAA 1YUXA 3I4NL 1PFUA 1SMUA 3J7Y1 5M5YL 1C09A 3P2AA 4A3IL 2E2HL 5IYBL 1I6HL 2AUSB 5FJ8L 7RXNA 1TWAL 4B8CD 3I4ML 1PFYA 1QCVA 3GTGL 1NNQA 2HR5A 1BQ8A 2NYDA 1IRNA 1YK4A 3LWOB 3PO2L 2R7ZL 2Z3RB 2PSMC 3S1NL 1YK5A 3LPEB 2J9UB 5DM61 4A3GL 1TWGL 1DX8A 2MS3A 3KYWA 5C4JL 4AHWA 5EIOC 5IYCL 2B63L 3PIP1 1RDGA 3PL5A 2E2JL 4A3CL 3H9CA 2PPTA 3PO3L 2CKAA 5RXNA 2V0EA 1IU6A 5M5XL 2NVYL 2VUML 1T9OA 5IYDL 3M3YL 1Y1WL 1R0GA 3P8BA 3RZDL 1H7VA 3S1QL 1LKPA 2WAQP 4AHYA 1K83L 2ERJA 4A3LL 2M6OA 3HOZL 2JI3A 4XXBB 3RZ6A 2O5JD 1TWCL 5IP9L 5EINC 3J7Z1 2BE5D 4Y52L 3RYGA 3GTOL 5M3ML 3LWQB 3MQKB 5M5WL 4V196 2DSXA 4A3BL 2APOB 3PKIA 2RFKB 4A3FL 4AI2A 4A3JL 2AQCA 3RZOL 3HKZP 1OWCA 5GAGc 2JA7L 2JI2A 3PWFA 5JVG1 1RYTA 3HOWL 3LNLA 2AYJA 2K2DA 4U671 1QYBA 5GADc 2C6BA 3S15L 3KYUA 3PIO1 5C4XL 4G6BA 1IROA 1B13A 2CKCA 5IP7L 1SMMA 1LKOA 4JAGA 2A6HD 2JA6L 3B08B 5H1Sc 3S2HL 1B2OA 3LWVB 2NVTL 1PFWA 3H97A 2R92L 3QVDA 5AI2A 4Y7NL 4TVMA 4JAFA 1VZGA 3WWNB 2E2IL 5AI3A 2YU9L 3H0GL 2XJPA 3PZAA 1S2ZA 4XGHA 2M4VA 4WFN1 2NVXL 5C44L 2M6PA 4AI0A 4ZN3B 1RWDA 3HJWB 4QIWP 5C3EL 2H12A 2C6AA 2QL0A 3LWPB 3B0AB 2KN9A 8RXNA 5K2ME 5MF6A 5DM71 1BQ9A 4AR3A 4AI3A 1R0HA 4ME3A 2V3BB 1R0FA 1JYBA 4C2M1 2LCQA 1TWHL 3WWLA 4X6AL 1PFVA 4A93L 5GAHc 4RXNA 3FKIL 2HVYC 1PZXA 2V0FA 4TPUA 4POGA 1QQTA 4AR6A 4UY81 1YUZA 2L0ZA 2CR8A 1S30A 1B71A 4LHLA 2XJUA 1S24A 1IU5A 5MLC3 4YWLA 2A69D 1SFOL 5MGNA 3JR7A 4C3HL 3M4OL 1P7PA 4AHZA 2Y0SP 1I3QL 4BBRL 3HJYB 1RDVA 5GAEc 4BXXL 3VPBE 4AHXA 2PVEA 3PKJA 3H99A 1E8JA 2PYAA 5M3FL 1Z92B 1VCXA 3SS2A 4AR4A 3GTJL 4AYBP 1OWBA 2A6ED 1Y1VL 2PMZP 2XJQA 1VZIA 4BY1L 1B2JA 2VL6A 2RDVA 1WCML 1BRFA 1SMWA 2GMGA 2KKDA 4A3DL 2XJTA 3CQZL 5JVH1 4BBSL 1CADA 1NXEA 3HOYL 1RYQA 4JADA 1RB9A 5IY0A 2JI1A 2JA8L 3HOUL 3GTML 3H3VM 4LHNA 1F4LA 1DVBA 3NFPI 4AR5A 3KYXA 1TWFL 3FDJA 3HOVL 2EY4E 3LWRB 4A3KL 1FHHA 3MSUA 4BY7L 4YWMA 1I50L 2B5ID 2ERSA 4C3JL 3S2DL 1NXGA 1VZHA 4K9FA 1WJVA 3HAXC 4C3IL 3H9BA 2XJRA 3K35A 4ZN1B 5MFZA 3QQCE 1YV1A 4GS7D 4POFA 2XJVA 6RXNA 4E6YA 3IU3I 2R93L 1R0IA 3GTKL 1ZRPA 1T9PA 1R0JA 3HOXL 2NVQL 4AI1A
chains in the Genus database with same CATH topology
2WB1P 5C4JL 3S17L 2JA6L 4A3EL 3S2HL 5IYCL 2B63L 2NVTL 3S1RL 2R92L 3GTLL 1TWGL 3GTJL 4AYBP 4Y7NL 2E2JL 4A3CL 1Y1VL 2PMZP 3S14L 3PO3L 4BY1L 3GTQL 4A3ML 3K7AL 1WCML 5M5XL 2E2IL 2NVYL 2VUML 2YU9L 5FLML 5IYDL 4A3DL 3M3YL 3H0GL 1Y1WL 3CQZL 3S1ML 3RZDL 4BBSL 2NVXL 5C44L 2JA5L 3GTPL 3S1QL 1R9TL 3HOYL 2JA8L 3HOUL 3GTML 2WAQP 1K83L 4QIWP 5C3EL 3H3VM 4A3LL 3HOZL 1TWCL 3S16L 5IP9L 1TWFL 3I4NL 3HOVL 4A3KL 5M5YL 4BY7L 4A3IL 2E2HL 4Y52L 1I50L 5IYBL 1I6HL 3GTOL 4C2M1 4C3JL 5M3ML 1TWHL 3S2DL 4X6AL 5M5WL 4A93L 5FJ8L 4A3BL 4C3IL 1TWAL 3FKIL 3I4ML 4A3FL 3GTGL 4A3JL 3RZOL 3HKZP 2JA7L 3PO2L 2R7ZL 3S1NL 3HOWL 1SFOL 4C3HL 3M4OL 2R93L 3GTKL 2Y0SP 4A3GL 1I3QL 4BBRL 3S15L 5C4XL 4BXXL 5IP7L 3HOXL 2NVQL 5M3FL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WB1 P;  5C4J L;  3S17 L;  2JA6 L;  4A3E L;  3S2H L;  5IYC L;  2B63 L;  2NVT L;  3S1R L;  2R92 L;  3GTL L;  1TWG L;  3GTJ L;  4AYB P;  4Y7N L;  2E2J L;  4A3C L;  1Y1V L;  2PMZ P;  3S14 L;  3PO3 L;  4BY1 L;  3GTQ L;  4A3M L;  3K7A L;  1WCM L;  5M5X L;  2E2I L;  2NVY L;  2VUM L;  2YU9 L;  5FLM L;  5IYD L;  4A3D L;  3M3Y L;  3H0G L;  1Y1W L;  3CQZ L;  3S1M L;  3RZD L;  4BBS L;  2NVX L;  5C44 L;  2JA5 L;  3GTP L;  3S1Q L;  1R9T L;  3HOY L;  2JA8 L;  3HOU L;  3GTM L;  2WAQ P;  1K83 L;  4QIW P;  5C3E L;  3H3V M;  4A3L L;  3HOZ L;  1TWC L;  3S16 L;  5IP9 L;  1TWF L;  3I4N L;  3HOV L;  4A3K L;  5M5Y L;  4BY7 L;  4A3I L;  2E2H L;  4Y52 L;  1I50 L;  5IYB L;  1I6H L;  3GTO L;  4C2M 1;  4C3J L;  5M3M L;  1TWH L;  3S2D L;  4X6A L;  5M5W L;  4A93 L;  5FJ8 L;  4A3B L;  4C3I L;  1TWA L;  3FKI L;  3I4M L;  4A3F L;  3GTG L;  4A3J L;  3RZO L;  3HKZ P;  2JA7 L;  3PO2 L;  2R7Z L;  3S1N L;  3HOW L;  1SFO L;  4C3H L;  3M4O L;  2R93 L;  3GTK L;  2Y0S P;  4A3G L;  1I3Q L;  4BBR L;  3S15 L;  5C4X L;  4BXX L;  5IP7 L;  3HOX L;  2NVQ L;  5M3F L; 
#chains in the Genus database with same CATH topology
 3RZT A;  2WB1 P;  3S17 L;  4A3E L;  2PVX A;  2A68 D;  3MPS A;  3S1R L;  3GTL L;  1LKM A;  3S14 L;  3GTQ L;  3KYV A;  4A3M L;  1FHM A;  3ZG6 A;  3K7A L;  2Z3Q B;  1LTL A;  5AN9 H;  5FLM L;  2M4Y A;  4JAE A;  3S1M L;  1IW7 D;  2XJS A;  2JA5 L;  3GTP L;  3KYY A;  1R9T L;  1T9Q A;  5MFP A;  3A44 A;  1ODH A;  1BE7 A;  1BFY A;  2ZIX A;  3S16 L;  1CAA A;  1YUX A;  3I4N L;  1PFU A;  1SMU A;  3J7Y 1;  5M5Y L;  1C09 A;  3P2A A;  4A3I L;  2E2H L;  5IYB L;  1I6H L;  2AUS B;  5FJ8 L;  7RXN A;  1TWA L;  4B8C D;  3I4M L;  1PFY A;  1QCV A;  3GTG L;  1NNQ A;  2HR5 A;  1BQ8 A;  2NYD A;  1IRN A;  1YK4 A;  3LWO B;  3PO2 L;  2R7Z L;  2Z3R B;  2PSM C;  3S1N L;  1YK5 A;  3LPE B;  2J9U B;  5DM6 1;  4A3G L;  1TWG L;  1DX8 A;  2MS3 A;  3KYW A;  5C4J L;  4AHW A;  5EIO C;  5IYC L;  2B63 L;  3PIP 1;  1RDG A;  3PL5 A;  2E2J L;  4A3C L;  3H9C A;  2PPT A;  3PO3 L;  2CKA A;  5RXN A;  2V0E A;  1IU6 A;  5M5X L;  2NVY L;  2VUM L;  1T9O A;  5IYD L;  3M3Y L;  1Y1W L;  1R0G A;  3P8B A;  3RZD L;  1H7V A;  3S1Q L;  1LKP A;  2WAQ P;  4AHY A;  1K83 L;  2ERJ A;  4A3L L;  2M6O A;  3HOZ L;  2JI3 A;  4XXB B;  3RZ6 A;  2O5J D;  1TWC L;  5IP9 L;  5EIN C;  3J7Z 1;  2BE5 D;  4Y52 L;  3RYG A;  3GTO L;  5M3M L;  3LWQ B;  3MQK B;  5M5W L;  4V19 6;  2DSX A;  4A3B L;  2APO B;  3PKI A;  2RFK B;  4A3F L;  4AI2 A;  4A3J L;  2AQC A;  3RZO L;  3HKZ P;  1OWC A;  5GAG c;  2JA7 L;  2JI2 A;  3PWF A;  5JVG 1;  1RYT A;  3HOW L;  3LNL A;  2AYJ A;  2K2D A;  4U67 1;  1QYB A;  5GAD c;  2C6B A;  3S15 L;  3KYU A;  3PIO 1;  5C4X L;  4G6B A;  1IRO A;  1B13 A;  2CKC A;  5IP7 L;  1SMM A;  1LKO A;  4JAG A;  2A6H D;  2JA6 L;  3B08 B;  5H1S c;  3S2H L;  1B2O A;  3LWV B;  2NVT L;  1PFW A;  3H97 A;  2R92 L;  3QVD A;  5AI2 A;  4Y7N L;  4TVM A;  4JAF A;  1VZG A;  3WWN B;  2E2I L;  5AI3 A;  2YU9 L;  3H0G L;  2XJP A;  3PZA A;  1S2Z A;  4XGH A;  2M4V A;  4WFN 1;  2NVX L;  5C44 L;  2M6P A;  4AI0 A;  4ZN3 B;  1RWD A;  3HJW B;  4QIW P;  5C3E L;  2H12 A;  2C6A A;  2QL0 A;  3LWP B;  3B0A B;  2KN9 A;  8RXN A;  5K2M E;  5MF6 A;  5DM7 1;  1BQ9 A;  4AR3 A;  4AI3 A;  1R0H A;  4ME3 A;  2V3B B;  1R0F A;  1JYB A;  4C2M 1;  2LCQ A;  1TWH L;  3WWL A;  4X6A L;  1PFV A;  4A93 L;  5GAH c;  4RXN A;  3FKI L;  2HVY C;  1PZX A;  2V0F A;  4TPU A;  4POG A;  1QQT A;  4AR6 A;  4UY8 1;  1YUZ A;  2L0Z A;  2CR8 A;  1S30 A;  1B71 A;  4LHL A;  2XJU A;  1S24 A;  1IU5 A;  5MLC 3;  4YWL A;  2A69 D;  1SFO L;  5MGN A;  3JR7 A;  4C3H L;  3M4O L;  1P7P A;  4AHZ A;  2Y0S P;  1I3Q L;  4BBR L;  3HJY B;  1RDV A;  5GAE c;  4BXX L;  3VPB E;  4AHX A;  2PVE A;  3PKJ A;  3H99 A;  1E8J A;  2PYA A;  5M3F L;  1Z92 B;  1VCX A;  3SS2 A;  4AR4 A;  3GTJ L;  4AYB P;  1OWB A;  2A6E D;  1Y1V L;  2PMZ P;  2XJQ A;  1VZI A;  4BY1 L;  1B2J A;  2VL6 A;  2RDV A;  1WCM L;  1BRF A;  1SMW A;  2GMG A;  2KKD A;  4A3D L;  2XJT A;  3CQZ L;  5JVH 1;  4BBS L;  1CAD A;  1NXE A;  3HOY L;  1RYQ A;  4JAD A;  1RB9 A;  5IY0 A;  2JI1 A;  2JA8 L;  3HOU L;  3GTM L;  3H3V M;  4LHN A;  1F4L A;  1DVB A;  3NFP I;  4AR5 A;  3KYX A;  1TWF L;  3FDJ A;  3HOV L;  2EY4 E;  3LWR B;  4A3K L;  1FHH A;  3MSU A;  4BY7 L;  4YWM A;  1I50 L;  2B5I D;  2ERS A;  4C3J L;  3S2D L;  1NXG A;  1VZH A;  4K9F A;  1WJV A;  3HAX C;  4C3I L;  3H9B A;  2XJR A;  3K35 A;  4ZN1 B;  5MFZ A;  3QQC E;  1YV1 A;  4GS7 D;  4POF A;  2XJV A;  6RXN A;  4E6Y A;  3IU3 I;  2R93 L;  1R0I A;  3GTK L;  1ZRP A;  1T9P A;  1R0J A;  3HOX L;  2NVQ L;  4AI1 A; 
#chains in the Genus database with same CATH homology
 2WB1 P;  5C4J L;  3S17 L;  2JA6 L;  4A3E L;  3S2H L;  5IYC L;  2B63 L;  2NVT L;  3S1R L;  2R92 L;  3GTL L;  1TWG L;  3GTJ L;  4AYB P;  4Y7N L;  2E2J L;  4A3C L;  1Y1V L;  2PMZ P;  3S14 L;  3PO3 L;  4BY1 L;  3GTQ L;  4A3M L;  3K7A L;  1WCM L;  5M5X L;  2E2I L;  2NVY L;  2VUM L;  2YU9 L;  5FLM L;  5IYD L;  4A3D L;  3M3Y L;  3H0G L;  1Y1W L;  3CQZ L;  3S1M L;  3RZD L;  4BBS L;  2NVX L;  5C44 L;  2JA5 L;  3GTP L;  3S1Q L;  1R9T L;  3HOY L;  2JA8 L;  3HOU L;  3GTM L;  2WAQ P;  1K83 L;  4QIW P;  5C3E L;  3H3V M;  4A3L L;  3HOZ L;  1TWC L;  3S16 L;  5IP9 L;  1TWF L;  3I4N L;  3HOV L;  4A3K L;  5M5Y L;  4BY7 L;  4A3I L;  2E2H L;  4Y52 L;  1I50 L;  5IYB L;  1I6H L;  3GTO L;  4C2M 1;  4C3J L;  5M3M L;  1TWH L;  3S2D L;  4X6A L;  5M5W L;  4A93 L;  5FJ8 L;  4A3B L;  4C3I L;  1TWA L;  3FKI L;  3I4M L;  4A3F L;  3GTG L;  4A3J L;  3RZO L;  3HKZ P;  2JA7 L;  3PO2 L;  2R7Z L;  3S1N L;  3HOW L;  1SFO L;  4C3H L;  3M4O L;  2R93 L;  3GTK L;  2Y0S P;  4A3G L;  1I3Q L;  4BBR L;  3S15 L;  5C4X L;  4BXX L;  5IP7 L;  3HOX L;  2NVQ L;  5M3F L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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