4CDFA

Human dpp1 in complex with (2s,4s)-n-((1s)-1-cyano-2-(4-(4- cyanophenyl)phenyl)ethyl)-4-hydroxy-piperidine-2-carboxamide
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
120
structure length
120
Chain Sequence
DTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVGT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords DIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAIN
total genus 26
structure length 120
sequence length 120
chains with identical sequence D
ec nomenclature ec 3.4.14.1: Dipeptidyl-peptidase I.
pdb deposition date 2013-10-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08773 CathepsinC_exc Cathepsin C exclusion domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.128.80 Mainly Beta Beta Barrel Lipocalin Cathepsin C, exclusion domain 4cdfA00
2DJFA 3PDFA 1JQPA 4OEMA 4CDDA 2DJGA 1K3BA 4CDCA 4CDFA 4OELA 4CDEA
chains in the Genus database with same CATH superfamily
3LHNA 1A2DA 4ML7B 1T68X 1MOYA 4O4UA 2OY7A 3AKNA 4NYQA 1UYOX 5HA1A 1I06A 2RTNB 5B29A 4AZQA 4ZH9A 1PMPA 3IFBA 1LFOA 1U17A 3FMZA 3NBXX 4LZUA 5EZ2A 3WJBA 1EPBA 1MUPA 3WZQA 1EXSA 4EDEA 1KL3A 2AKQA 3ZUOA 2ALLX 1Y9LA 3NQKA 3OBLA 2IZLB 4YFPA 5IRAA 2KW1A 3RDUA 3ZZVA 2OL6O 5LJCA 1JYJA 5B5GA 4GDZA 1GKAA 2OY1O 1ACDA 1QFVA 2BS6A 2QOSC 2RQ0A 2YMSA 2FS7A 2WQ9A 2PI3O 4ORWA 1I04A 2RD7C 1Y52X 4ORUA 4BX6B 1BBPA 1I4UA 2GTLO 1LNMA 4GNYA 1VWOB 2FT9A 4EQAC 3WOVA 5IO7A 4A1YA 1TVQA 4CDFA 2AT5X 4FBVA 2C4IA 2Q2MA 2QM9A 4MVIA 2A5BA 2VFCA 2NP1A 3BX7A 5HAEA 4QNIA 4ON1A 1BLRA 5F2BA 1ERBA 3ZW0B 5FQ8E 4U3QA 4OMXA 4TJZA 3ZWEA 3KQ0A 2IZEB 4KC7A 1HMTA 2YG2A 5IXGA 5BYPA 4ORYA 1OEJA 2RTKA 1BRPA 1LCWA 2HYSA 1Y55X 4GGRA 4O3XB 2FS6A 1DZMA 1SWHA 3FA8A 3PECA 4CPHA 3APUA 4EKVA 4YVBA 2VDFA 3TF6A 4IAWA 4JHQA 4TKHA 3FEKA 3MG5A 3N91A 1ICNA 1NGLA 3AKMA 1RSUB 5AJBA 4UU3A 3OD9A 4GH7A 3S5VA 1VWQB 5FQ6E 1HXZA 3P6GA 3U9PC 4ZGUA 1ZNDA 5EEDA 2F01A 3RE6A 3RY2A 1SRJA 1SLDB 2KD2A 4YH0A 3RBYA 1DZJA 2FKJA 4Y5DA 4AZMA 1GT5A 1PBYA 1N9MA 3HOEA 1ZNEA 3HWGA 1EI5A 3LTWA 4OS0A 4QYNA 4U8UM 1SA8A 2RA6A 3EM0A 2QO5A 5KICA 3SZJA 1B0OA 4ID2A 4HPBA 1LUQA 1TW4A 1QY2A 2GC9A 1SRHA 3G7XA 4ODDA 2E4JA 4BBOA 3E3CA 4A1HA 2OFRX 1BSYA 2RN4A 1CBSA 4Z2OA 4L3RA 2ZAIA 3B2KA 1KGLA 4AZOA 1OPAA 3I0AA 1YWCA 5F1EA 3DTQA 3RKGA 2I5VO 5EDCA 2GTFX 1EUOA 2LFOA 2RTMA 4Z2PA 3NP1A 2FHLA 4NP1A 1X71A 3NQ3A 1PEEA 4HPDA 2C1SA 3FW4A 4L1NA 1N7YA 1A3YA 1HMSA 3PDFA 2IZKA 4LKPA 1AVGI 1YWDA 2Q4NA 3EBKA 4IB9A 4N7DA 1ICMA 2BHVA 2RTAA 4YBUA 3WJDA 1TOUA 1IFCA 1GT4A 3ZW1A 1E02A 2R73A 3WJEA 2A2UA 1VWHB 2X8TA 2G78A 1FE3A 1BRQA 3BDRA 1MM9A 2LBAA 4XMCA 1SWEA 1CRBA 2RTJA 1JJUA 2CBSA 3HWFA 4RUNA 1NBXA 1IIUA 2Q2PA 2RTDB 3EW2A 3GAQA 1UZ2X 2ACOA 3B2JA 3P6FA 3ZI8A 3AUMO 3VU1A 1VWKB 1JYDA 1VWFB 4JNJA 4NV7A 4I3BA 3VG2A 3VG5A 3WJFA 1RBPA 1O1UA 1E5PA 4NLJA 3O19A 1B8EA 4FBOA 4IB7A 1UREA 1B4MA 2G7BA 3PQUA 5H9LA 3EMMA 4Z27A 2X46A 5F6BA 5HBSA 3FELA 2RTRB 1GGLA 4TKJA 4AZNA 2HMBA 1N43A 2WSJA 1WBIA 4O3WA 5DG4A 3AEHA 1MX8A 1SLEB 1STRB 4B55A 1DC9A 1W5RA 5HZ5A 1VWDB 2M4LA 3DSZA 4BX6A 4CDDA 1G85A 5CHKA 3OE3A 4WFUA 3P6HA 4GZVA 1SWLA 4AZRA 1CBIA 5LKEA 3ZUIA 1T8VA 4CK4A 2L67A 1K24A 2MWHA 1VYFA 2NNDA 4OS8A 1MEPA 3FW5A 1OPBA 5HCEC 3RSWA 4ARHA 3CMPA 1IW2A 1LPJA 4BX7B 4WFVA 4CPIA 4QGVA 3WVMA 2JU7A 3HWEA 5EEEA 4NYRA 3ZW0A 1FEMA 1OSPO 3ZW1B 4BX5B 4ZCBA 1NC9A 3HPEA 4BVMA 5H9NA 3D4RA 5D48A 2NNEA 4DQ3A 1X8NA 1YWBA 2OVAA 4M6SA 5HA0A 1HXLA 2A2GA 1VWNB 4HPAA 4YCHA 1SRFA 4N7CA 1JJJA 5D8JA 1EW3A 1EPAA 1HY2A 5L8NA 4ORSA 4CSBA 3FR4A 4Y0SA 2GTLM 1SWPA 3FENA 2X4MA 3S60A 2RTIB 2X8SA 2P8GA 4XMGA 3EC5A 4WHIA 4CPEA 1FENA 1LF7A 1QY0A 1SY1A 5FQ7E 5LJBA 5LJGA 2OL8O 1QQSA 5L8OA 3JQOA 1N0SA 1P6PA 5LKFA 3MBTA 2W2BA 4CDCA 4ORXA 5LJKA 4GJSA 3RWXA 1SXXA 3KFHA 4O49A 3CR6A 3X00A 4JO6A 5BVSA 1PBOA 3D95A 1VWGB 2LKKA 1CBRA 4WBKA 1NQMA 1SWCA 2AF5A 2OF8A 3NPOA 1S44A 3BSZE 1SXUA 4GETA 4QGXA 1QABE 1Y53X 4YMYA 2BLGA 1HN2A 2AMMX 4YBPA 1KZWA 2Z4HA 5L8IA 1IJ8A 4ZFXA 3P02A 1SY2A 4GE1A 2HNXA 2L68A 4YDBA 5D45A 3SLJA 3P24A 1N4JA 2POAA 1KL4A 1BM5A 4DCBA 1MDCA 1PTSA 3NX1A 3SOTA 1LCZA 1RXJA 3BS2A 5D4AA 3SLOA 1X89A 5IRWA 2DJGA 1HQPA 1DF8A 1KL5A 5B27A 3STKA 3VPJE 2A3FX 2AT3X 1EALA 2FKGA 2IZDB 2BSZA 1O1VA 2OF9A 1SREA 3B2IA 4GGTA 4NV8A 2OZQA 4IB8A 4ORRA 3HK1A 2WEWA 3K3LA 1EIOA 1VYGA 1CJ5A 1Z24A 2QO4A 3JS1A 1KQWA 2RCQA 5B3MO 4BGFA 3IA8A 3C76X 2DJFA 2CZUA 2G79A 3WXQA 3ZQ3A 4TQ2A 2RTEB 1SWSA 3KFIA 1NP4A 2FHNX 4YCEA 3P6DA 3P6EA 1KOIA 2KT4B 2XSTA 2QMIA 4IMOA 2IZCB 5C0NA 5BVTA 1K3BA 1XCAA 4I9RA 4YFQA 3STMX 4IRWA 4PSQA 4ZHDA 2CBRA 4GNWA 1VWCB 3PP6A 3P6CA 1LICA 4Y0QA 3VE1A 2Z4IA 5F58A 1FJ1E 1LKEA 2UYWA 1YP7A 2AT6X 2X56A 1QWDA 1EQDA 2Y32A 1LIEA 4CDEA 1N9YA 1RLBE 1RXKA 1SWRA 3WYPA 4LKTA 4GGZA 1S2PA 1IKEA 1SLGB 4I3DA 5DPQA 1ADLA 4GK9A 4MIRA 5JR8A 3PEDA 1Y9TA 1L6MA 1DZPA 3D9WA 1A18A 4KCAA 1R0UA 1ZNLA 1OBPA 1GX8A 4UU2A 3ELZA 3WZPA 1SMPI 1SWUA 1HBQA 2X55A 1HBPA 5K68A 1X8PA 4EXZA 3MVFA 1G74A 4BX7A 2A13A 3UAQA 3APWA 1OEKA 2OY5O 1WUBA 2RCTA 1SWGA 4IAXA 1NDJA 3WJGA 4BJ8A 4BX5A 3VG4A 3APXA 4KC8A 1QFTA 2G8CO 1LIBA 2Y3FA 5L3YA 1XKIA 3GE2A 3SZIA 1BWYA 1SLFB 1U18A 1W4TA 3S26A 3RY1A 1CBQA 2A8GA 1JIWI 2FRSA 2UZ2A 3O2YA 5AEOA 4YKOA 2IZBA 3CQRA 3FR5A 5AJCA 5KHPA 2FLJA 4QAEA 1D2UA 2IZHB 1KT7A 1VWEB 2AT0X 3RDMA 1SRIA 2CM9A 1G5WA 1X8OA 1QY1A 4QQ1A 3FYFA 5FENA 4NW4A 5HCCC 2RTLA 3JSQA 3FLLA 2HKDA 3BRNA 1OBUA 2X32A 1JJXA 1I9HA 3CKFA 2QOMA 1MX7A 3CBSA 2A0AA 2LB6A 3V8UA 1A57A 4FBRA 4Y59A 1JMZA 1SY3A 2NNQA 2WQAE 1SWBA 2GJ5A 2OVEA 3HWDA 3VG6A 4C5PA 1BSQA 1LDOA 2IZGB 4MVLA 5H9KA 2LBVA 3NQ9A 4ALOA 4Z2VA 2AT8X 1ZNKA 2HZQA 3MX7A 4GD9A 4JGLA 3UEVA 4IMNA 1LIFA 4GKCA 1E00A 4QRLA 5CSEA 4U9CA 1I05A 3F6ZB 1FDQA 1B56A 4PJ2A 5LJHA 1GM6A 2BS5A 3PH6A 3T6LA 4A60A 1RSTB 2F73A 4Y0RA 1SXWA 4GDAA 1NP1A 1ML7A 2K23A 2W2AA 4ZH6A 1VWMB 3QQ2A 4ZHFA 1VWAB 2RTGB 4DQ4A 1AVEA 1DFVA 1YUPA 4K19A 4YGGA 3KZAA 4YGZA 2FR3A 3CWKA 2Y3EA 5H8TA 1VWJB 4ZHHA 5EPQA 3MM0A 4BQUA 1VWPB 1IFBA 2IZAA 2K62A 3CQNA 3OJYC 4COTA 2CAMA 1HQQA 2AH7X 4HPCA 5B5FA 1Y0GA 3EYCA 1O8VA 2MM3A 4ALBA 4EEJA 4Z28A 2VFBA 1JQPA 1YP6A 1JZUA 3RZYA 4TNNA 1DF3A 2RTPB 1UYNX 3BU1A 3CKGA 2MO5A 4FQBB 1LCVA 4M7MA 1I78A 5B10O 1T0VA 3VE2A 1VWRB 1GX3A 5F6ZA 4IABA 2JOZA 5LJEA 3S5XA 1W6FA 2R56A 2R74A 4QYPA 4YGHA 3VHHA 3H3IA 3KFFA 3FIQA 2RTFB 4U8UN 1NQNA 5AQ6A 5CE4A 4MISA 1X8QA 1EIIA 4CPFA 2BT9A 2HLVA 5FFHA 3UEWA 3T6FA 1ZNHA 2CZTA 2IZJA 3EBWA 4XMFA 5CYBA 5H9AA 4AW8A 1RXHA 1SWDA 4D6AA 4IBAA 4OS3A 2HZRA 4MVKA 5HZQA 2C1QA 2WPUA 2OYBO 3T1DA 1SWJA 4NLIA 2PY1A 1S7DA 2RTOB 1D3SA 4XMEA 4YDAA 3D97A 1KT6A 3D96A 3Q6LA 4O9SA 1SXYA 3EW1A 1VPRA 4U46A 4OKAA 1DV9A 3BY0A 5D47A 1VWLB 2L5PA 2QCBA 4EFGA 2ZAGA 2FGSA 2OVDA 4FGIB 3BX8A 1QG5A 2L9CA 4TKBA 2FR2A 3NADA 1FELA 5HCDC 4I9SA 3FIDA 1GT3A 4AYHA 4BOEA 1MVGA 2DM5A 4O3ZA 4RUUA 5HZ9A 1PM1X 1FTPA 4I95A 3WJCA 2ASNX 3T2WA 1OBQA 2WWPA 3FEPA 4KH8A 2WUTA 3RDOA 2KTDA 1SWKA 1GKAB 1TXLA 3I17A 2ACPX 4OMWA 1STPA 1LIDA 3T2XA 2Q9SA 4ZGFA 1E2TA 3NR3A 3SLTA 1VYOA 4ZR2A 2WEXA 1OEEA 3KVNA 1LELA 4MVEA 4KIIA 5EDBA 4CV7A 1SRGA 4I60A 4R0BA 1ERXA 1KXOA 1AVDA 4BCSA 4HWMA 3C77X 2RTQB 1JV4A 5HZ6A 2IZIA 1KT4A 3U0DA 3QKGA 1YIVA 5B11O 4AZPA 2OFMX 4KT5A 1KT3A 4YFRA 2MHDA 4QZTA 1ZRYA 2LA7A 2XKLA 2OFBA 1HMRA 3HTYA 4MEEA 3KFGA 3UEXA 3WBGA 1GXAA 2FWVA 3RDQA 2O62A 1KFFA 2RTCB 4U8UO 3O22A 3RDSA 4CPHB 4Z6JA 1X8UA 3NX2A 2G5LA 3VGWA 5HTDA 2JW1A 3LV4A 2ANSA 2OVSA 4GRJA 2RTHB 4QZUA 5IO6A 3TGBA 4XMHA 3STNA 3FDCA 3F9DA 4LQZA 1LDQA 3ZW2A 4ZHGA 1RAVA 4TLJA 2AVIA 5LJDA 5HZ8A 1AELA 1H91A 1KT5A 5F7GA 3PPTA 2MJIA 5FAZA 2CM4A 3BU9A 3FA7A 4YKMA 4A8ZA 2JN3A 1DZKA 2JU8A 3F8AA 1SWAA 2X34A 4ZJ0A 1AQBA 3FR2A 2N93A 4DNEA 2JMBA 3WZNA 4GU8A 3SZHA 1ALBA 5HWZA 1VWBB 2A5CA 1VWIB 2WR6A 4LZVA 5BVQA 2GTLN 5K06A 5B2AO 1JMXA 2OFAA 3PK2A 2W2FA 2EU7X 1SWFA 5HTEA 3UEUA 3CBCA 3U03A 1GT1A 1GX9A 4GJVA 4IB6A 4QGWA 4OELA 1IKJA 1BJ7A 1SWNA 2OL7A 2ZSCA 1SWQA 3B2HA 2OY8A 1SY0A 3FA6A 3SAOA 2JGSA 1SWOA 3PQSA 3RE5A 2GH7A 3TGCA 2AL0X 1STSB 1JBHA 1U0XA 4NNSA 2JU3A 2Q39A 5K67A 4Y0PA 3WZOA 3BLGA 1KQXA 2X8FA 3FA9A 4O4OA 5JD2A 3RDXA 1KZXA 3Q34A 1ZNGA 3VG3A 5KIDA 2I5ZO 3B2LA 3TGAA 1AB0A 4ZHCA 4NNTA 1TOWA 2IFBA 3PH5A 4HFOA 4O3YA 1SWTA 4D6BA 5IO5A 3TZSA 4I3CA 3VHMA 1BSOA 4I6SA 4XMDA 5IRUA 4O4XA 3C78X 2X45A 4GUZA 4ES7A 2RTBB 1YWAA 1E06A 3VHIA 3HOLA 2KTSA 2FTBA 2BC3A 3ELXA 3L4RA 4O4SA 4OEMA 3WYQA 2IZFB 1BEBA 1MK5A 2MF6A 2QO6A 3VG7A 1G7NA 4INNA 3APVA 2F09A
chains in the Genus database with same CATH topology
2DJFA 3PDFA 1JQPA 4OEMA 4CDDA 2DJGA 1K3BA 4CDCA 4CDFA 4OELA 4CDEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DJF A;  3PDF A;  1JQP A;  4OEM A;  4CDD A;  2DJG A;  1K3B A;  4CDC A;  4CDF A;  4OEL A;  4CDE A; 
#chains in the Genus database with same CATH topology
 3LHN A;  1A2D A;  4ML7 B;  1T68 X;  1MOY A;  4O4U A;  2OY7 A;  3AKN A;  4NYQ A;  1UYO X;  5HA1 A;  1I06 A;  2RTN B;  5B29 A;  4AZQ A;  4ZH9 A;  1PMP A;  3IFB A;  1LFO A;  1U17 A;  3FMZ A;  3NBX X;  4LZU A;  5EZ2 A;  3WJB A;  1EPB A;  1MUP A;  3WZQ A;  1EXS A;  4EDE A;  1KL3 A;  2AKQ A;  3ZUO A;  2ALL X;  1Y9L A;  3NQK A;  3OBL A;  2IZL B;  4YFP A;  5IRA A;  2KW1 A;  3RDU A;  3ZZV A;  2OL6 O;  5LJC A;  1JYJ A;  5B5G A;  4GDZ A;  1GKA A;  2OY1 O;  1ACD A;  1QFV A;  2BS6 A;  2QOS C;  2RQ0 A;  2YMS A;  2FS7 A;  2WQ9 A;  2PI3 O;  4ORW A;  1I04 A;  2RD7 C;  1Y52 X;  4ORU A;  4BX6 B;  1BBP A;  1I4U A;  2GTL O;  1LNM A;  4GNY A;  1VWO B;  2FT9 A;  4EQA C;  3WOV A;  5IO7 A;  4A1Y A;  1TVQ A;  4CDF A;  2AT5 X;  4FBV A;  2C4I A;  2Q2M A;  2QM9 A;  4MVI A;  2A5B A;  2VFC A;  2NP1 A;  3BX7 A;  5HAE A;  4QNI A;  4ON1 A;  1BLR A;  5F2B A;  1ERB A;  3ZW0 B;  5FQ8 E;  4U3Q A;  4OMX A;  4TJZ A;  3ZWE A;  3KQ0 A;  2IZE B;  4KC7 A;  1HMT A;  2YG2 A;  5IXG A;  5BYP A;  4ORY A;  1OEJ A;  2RTK A;  1BRP A;  1LCW A;  2HYS A;  1Y55 X;  4GGR A;  4O3X B;  2FS6 A;  1DZM A;  1SWH A;  3FA8 A;  3PEC A;  4CPH A;  3APU A;  4EKV A;  4YVB A;  2VDF A;  3TF6 A;  4IAW A;  4JHQ A;  4TKH A;  3FEK A;  3MG5 A;  3N91 A;  1ICN A;  1NGL A;  3AKM A;  1RSU B;  5AJB A;  4UU3 A;  3OD9 A;  4GH7 A;  3S5V A;  1VWQ B;  5FQ6 E;  1HXZ A;  3P6G A;  3U9P C;  4ZGU A;  1ZND A;  5EED A;  2F01 A;  3RE6 A;  3RY2 A;  1SRJ A;  1SLD B;  2KD2 A;  4YH0 A;  3RBY A;  1DZJ A;  2FKJ A;  4Y5D A;  4AZM A;  1GT5 A;  1PBY A;  1N9M A;  3HOE A;  1ZNE A;  3HWG A;  1EI5 A;  3LTW A;  4OS0 A;  4QYN A;  4U8U M;  1SA8 A;  2RA6 A;  3EM0 A;  2QO5 A;  5KIC A;  3SZJ A;  1B0O A;  4ID2 A;  4HPB A;  1LUQ A;  1TW4 A;  1QY2 A;  2GC9 A;  1SRH A;  3G7X A;  4ODD A;  2E4J A;  4BBO A;  3E3C A;  4A1H A;  2OFR X;  1BSY A;  2RN4 A;  1CBS A;  4Z2O A;  4L3R A;  2ZAI A;  3B2K A;  1KGL A;  4AZO A;  1OPA A;  3I0A A;  1YWC A;  5F1E A;  3DTQ A;  3RKG A;  2I5V O;  5EDC A;  2GTF X;  1EUO A;  2LFO A;  2RTM A;  4Z2P A;  3NP1 A;  2FHL A;  4NP1 A;  1X71 A;  3NQ3 A;  1PEE A;  4HPD A;  2C1S A;  3FW4 A;  4L1N A;  1N7Y A;  1A3Y A;  1HMS A;  3PDF A;  2IZK A;  4LKP A;  1AVG I;  1YWD A;  2Q4N A;  3EBK A;  4IB9 A;  4N7D A;  1ICM A;  2BHV A;  2RTA A;  4YBU A;  3WJD A;  1TOU A;  1IFC A;  1GT4 A;  3ZW1 A;  1E02 A;  2R73 A;  3WJE A;  2A2U A;  1VWH B;  2X8T A;  2G78 A;  1FE3 A;  1BRQ A;  3BDR A;  1MM9 A;  2LBA A;  4XMC A;  1SWE A;  1CRB A;  2RTJ A;  1JJU A;  2CBS A;  3HWF A;  4RUN A;  1NBX A;  1IIU A;  2Q2P A;  2RTD B;  3EW2 A;  3GAQ A;  1UZ2 X;  2ACO A;  3B2J A;  3P6F A;  3ZI8 A;  3AUM O;  3VU1 A;  1VWK B;  1JYD A;  1VWF B;  4JNJ A;  4NV7 A;  4I3B A;  3VG2 A;  3VG5 A;  3WJF A;  1RBP A;  1O1U A;  1E5P A;  4NLJ A;  3O19 A;  1B8E A;  4FBO A;  4IB7 A;  1URE A;  1B4M A;  2G7B A;  3PQU A;  5H9L A;  3EMM A;  4Z27 A;  2X46 A;  5F6B A;  5HBS A;  3FEL A;  2RTR B;  1GGL A;  4TKJ A;  4AZN A;  2HMB A;  1N43 A;  2WSJ A;  1WBI A;  4O3W A;  5DG4 A;  3AEH A;  1MX8 A;  1SLE B;  1STR B;  4B55 A;  1DC9 A;  1W5R A;  5HZ5 A;  1VWD B;  2M4L A;  3DSZ A;  4BX6 A;  4CDD A;  1G85 A;  5CHK A;  3OE3 A;  4WFU A;  3P6H A;  4GZV A;  1SWL A;  4AZR A;  1CBI A;  5LKE A;  3ZUI A;  1T8V A;  4CK4 A;  2L67 A;  1K24 A;  2MWH A;  1VYF A;  2NND A;  4OS8 A;  1MEP A;  3FW5 A;  1OPB A;  5HCE C;  3RSW A;  4ARH A;  3CMP A;  1IW2 A;  1LPJ A;  4BX7 B;  4WFV A;  4CPI A;  4QGV A;  3WVM A;  2JU7 A;  3HWE A;  5EEE A;  4NYR A;  3ZW0 A;  1FEM A;  1OSP O;  3ZW1 B;  4BX5 B;  4ZCB A;  1NC9 A;  3HPE A;  4BVM A;  5H9N A;  3D4R A;  5D48 A;  2NNE A;  4DQ3 A;  1X8N A;  1YWB A;  2OVA A;  4M6S A;  5HA0 A;  1HXL A;  2A2G A;  1VWN B;  4HPA A;  4YCH A;  1SRF A;  4N7C A;  1JJJ A;  5D8J A;  1EW3 A;  1EPA A;  1HY2 A;  5L8N A;  4ORS A;  4CSB A;  3FR4 A;  4Y0S A;  2GTL M;  1SWP A;  3FEN A;  2X4M A;  3S60 A;  2RTI B;  2X8S A;  2P8G A;  4XMG A;  3EC5 A;  4WHI A;  4CPE A;  1FEN A;  1LF7 A;  1QY0 A;  1SY1 A;  5FQ7 E;  5LJB A;  5LJG A;  2OL8 O;  1QQS A;  5L8O A;  3JQO A;  1N0S A;  1P6P A;  5LKF A;  3MBT A;  2W2B A;  4CDC A;  4ORX A;  5LJK A;  4GJS A;  3RWX A;  1SXX A;  3KFH A;  4O49 A;  3CR6 A;  3X00 A;  4JO6 A;  5BVS A;  1PBO A;  3D95 A;  1VWG B;  2LKK A;  1CBR A;  4WBK A;  1NQM A;  1SWC A;  2AF5 A;  2OF8 A;  3NPO A;  1S44 A;  3BSZ E;  1SXU A;  4GET A;  4QGX A;  1QAB E;  1Y53 X;  4YMY A;  2BLG A;  1HN2 A;  2AMM X;  4YBP A;  1KZW A;  2Z4H A;  5L8I A;  1IJ8 A;  4ZFX A;  3P02 A;  1SY2 A;  4GE1 A;  2HNX A;  2L68 A;  4YDB A;  5D45 A;  3SLJ A;  3P24 A;  1N4J A;  2POA A;  1KL4 A;  1BM5 A;  4DCB A;  1MDC A;  1PTS A;  3NX1 A;  3SOT A;  1LCZ A;  1RXJ A;  3BS2 A;  5D4A A;  3SLO A;  1X89 A;  5IRW A;  2DJG A;  1HQP A;  1DF8 A;  1KL5 A;  5B27 A;  3STK A;  3VPJ E;  2A3F X;  2AT3 X;  1EAL A;  2FKG A;  2IZD B;  2BSZ A;  1O1V A;  2OF9 A;  1SRE A;  3B2I A;  4GGT A;  4NV8 A;  2OZQ A;  4IB8 A;  4ORR A;  3HK1 A;  2WEW A;  3K3L A;  1EIO A;  1VYG A;  1CJ5 A;  1Z24 A;  2QO4 A;  3JS1 A;  1KQW A;  2RCQ A;  5B3M O;  4BGF A;  3IA8 A;  3C76 X;  2DJF A;  2CZU A;  2G79 A;  3WXQ A;  3ZQ3 A;  4TQ2 A;  2RTE B;  1SWS A;  3KFI A;  1NP4 A;  2FHN X;  4YCE A;  3P6D A;  3P6E A;  1KOI A;  2KT4 B;  2XST A;  2QMI A;  4IMO A;  2IZC B;  5C0N A;  5BVT A;  1K3B A;  1XCA A;  4I9R A;  4YFQ A;  3STM X;  4IRW A;  4PSQ A;  4ZHD A;  2CBR A;  4GNW A;  1VWC B;  3PP6 A;  3P6C A;  1LIC A;  4Y0Q A;  3VE1 A;  2Z4I A;  5F58 A;  1FJ1 E;  1LKE A;  2UYW A;  1YP7 A;  2AT6 X;  2X56 A;  1QWD A;  1EQD A;  2Y32 A;  1LIE A;  4CDE A;  1N9Y A;  1RLB E;  1RXK A;  1SWR A;  3WYP A;  4LKT A;  4GGZ A;  1S2P A;  1IKE A;  1SLG B;  4I3D A;  5DPQ A;  1ADL A;  4GK9 A;  4MIR A;  5JR8 A;  3PED A;  1Y9T A;  1L6M A;  1DZP A;  3D9W A;  1A18 A;  4KCA A;  1R0U A;  1ZNL A;  1OBP A;  1GX8 A;  4UU2 A;  3ELZ A;  3WZP A;  1SMP I;  1SWU A;  1HBQ A;  2X55 A;  1HBP A;  5K68 A;  1X8P A;  4EXZ A;  3MVF A;  1G74 A;  4BX7 A;  2A13 A;  3UAQ A;  3APW A;  1OEK A;  2OY5 O;  1WUB A;  2RCT A;  1SWG A;  4IAX A;  1NDJ A;  3WJG A;  4BJ8 A;  4BX5 A;  3VG4 A;  3APX A;  4KC8 A;  1QFT A;  2G8C O;  1LIB A;  2Y3F A;  5L3Y A;  1XKI A;  3GE2 A;  3SZI A;  1BWY A;  1SLF B;  1U18 A;  1W4T A;  3S26 A;  3RY1 A;  1CBQ A;  2A8G A;  1JIW I;  2FRS A;  2UZ2 A;  3O2Y A;  5AEO A;  4YKO A;  2IZB A;  3CQR A;  3FR5 A;  5AJC A;  5KHP A;  2FLJ A;  4QAE A;  1D2U A;  2IZH B;  1KT7 A;  1VWE B;  2AT0 X;  3RDM A;  1SRI A;  2CM9 A;  1G5W A;  1X8O A;  1QY1 A;  4QQ1 A;  3FYF A;  5FEN A;  4NW4 A;  5HCC C;  2RTL A;  3JSQ A;  3FLL A;  2HKD A;  3BRN A;  1OBU A;  2X32 A;  1JJX A;  1I9H A;  3CKF A;  2QOM A;  1MX7 A;  3CBS A;  2A0A A;  2LB6 A;  3V8U A;  1A57 A;  4FBR A;  4Y59 A;  1JMZ A;  1SY3 A;  2NNQ A;  2WQA E;  1SWB A;  2GJ5 A;  2OVE A;  3HWD A;  3VG6 A;  4C5P A;  1BSQ A;  1LDO A;  2IZG B;  4MVL A;  5H9K A;  2LBV A;  3NQ9 A;  4ALO A;  4Z2V A;  2AT8 X;  1ZNK A;  2HZQ A;  3MX7 A;  4GD9 A;  4JGL A;  3UEV A;  4IMN A;  1LIF A;  4GKC A;  1E00 A;  4QRL A;  5CSE A;  4U9C A;  1I05 A;  3F6Z B;  1FDQ A;  1B56 A;  4PJ2 A;  5LJH A;  1GM6 A;  2BS5 A;  3PH6 A;  3T6L A;  4A60 A;  1RST B;  2F73 A;  4Y0R A;  1SXW A;  4GDA A;  1NP1 A;  1ML7 A;  2K23 A;  2W2A A;  4ZH6 A;  1VWM B;  3QQ2 A;  4ZHF A;  1VWA B;  2RTG B;  4DQ4 A;  1AVE A;  1DFV A;  1YUP A;  4K19 A;  4YGG A;  3KZA A;  4YGZ A;  2FR3 A;  3CWK A;  2Y3E A;  5H8T A;  1VWJ B;  4ZHH A;  5EPQ A;  3MM0 A;  4BQU A;  1VWP B;  1IFB A;  2IZA A;  2K62 A;  3CQN A;  3OJY C;  4COT A;  2CAM A;  1HQQ A;  2AH7 X;  4HPC A;  5B5F A;  1Y0G A;  3EYC A;  1O8V A;  2MM3 A;  4ALB A;  4EEJ A;  4Z28 A;  2VFB A;  1JQP A;  1YP6 A;  1JZU A;  3RZY A;  4TNN A;  1DF3 A;  2RTP B;  1UYN X;  3BU1 A;  3CKG A;  2MO5 A;  4FQB B;  1LCV A;  4M7M A;  1I78 A;  5B10 O;  1T0V A;  3VE2 A;  1VWR B;  1GX3 A;  5F6Z A;  4IAB A;  2JOZ A;  5LJE A;  3S5X A;  1W6F A;  2R56 A;  2R74 A;  4QYP A;  4YGH A;  3VHH A;  3H3I A;  3KFF A;  3FIQ A;  2RTF B;  4U8U N;  1NQN A;  5AQ6 A;  5CE4 A;  4MIS A;  1X8Q A;  1EII A;  4CPF A;  2BT9 A;  2HLV A;  5FFH A;  3UEW A;  3T6F A;  1ZNH A;  2CZT A;  2IZJ A;  3EBW A;  4XMF A;  5CYB A;  5H9A A;  4AW8 A;  1RXH A;  1SWD A;  4D6A A;  4IBA A;  4OS3 A;  2HZR A;  4MVK A;  5HZQ A;  2C1Q A;  2WPU A;  2OYB O;  3T1D A;  1SWJ A;  4NLI A;  2PY1 A;  1S7D A;  2RTO B;  1D3S A;  4XME A;  4YDA A;  3D97 A;  1KT6 A;  3D96 A;  3Q6L A;  4O9S A;  1SXY A;  3EW1 A;  1VPR A;  4U46 A;  4OKA A;  1DV9 A;  3BY0 A;  5D47 A;  1VWL B;  2L5P A;  2QCB A;  4EFG A;  2ZAG A;  2FGS A;  2OVD A;  4FGI B;  3BX8 A;  1QG5 A;  2L9C A;  4TKB A;  2FR2 A;  3NAD A;  1FEL A;  5HCD C;  4I9S A;  3FID A;  1GT3 A;  4AYH A;  4BOE A;  1MVG A;  2DM5 A;  4O3Z A;  4RUU A;  5HZ9 A;  1PM1 X;  1FTP A;  4I95 A;  3WJC A;  2ASN X;  3T2W A;  1OBQ A;  2WWP A;  3FEP A;  4KH8 A;  2WUT A;  3RDO A;  2KTD A;  1SWK A;  1GKA B;  1TXL A;  3I17 A;  2ACP X;  4OMW A;  1STP A;  1LID A;  3T2X A;  2Q9S A;  4ZGF A;  1E2T A;  3NR3 A;  3SLT A;  1VYO A;  4ZR2 A;  2WEX A;  1OEE A;  3KVN A;  1LEL A;  4MVE A;  4KII A;  5EDB A;  4CV7 A;  1SRG A;  4I60 A;  4R0B A;  1ERX A;  1KXO A;  1AVD A;  4BCS A;  4HWM A;  3C77 X;  2RTQ B;  1JV4 A;  5HZ6 A;  2IZI A;  1KT4 A;  3U0D A;  3QKG A;  1YIV A;  5B11 O;  4AZP A;  2OFM X;  4KT5 A;  1KT3 A;  4YFR A;  2MHD A;  4QZT A;  1ZRY A;  2LA7 A;  2XKL A;  2OFB A;  1HMR A;  3HTY A;  4MEE A;  3KFG A;  3UEX A;  3WBG A;  1GXA A;  2FWV A;  3RDQ A;  2O62 A;  1KFF A;  2RTC B;  4U8U O;  3O22 A;  3RDS A;  4CPH B;  4Z6J A;  1X8U A;  3NX2 A;  2G5L A;  3VGW A;  5HTD A;  2JW1 A;  3LV4 A;  2ANS A;  2OVS A;  4GRJ A;  2RTH B;  4QZU A;  5IO6 A;  3TGB A;  4XMH A;  3STN A;  3FDC A;  3F9D A;  4LQZ A;  1LDQ A;  3ZW2 A;  4ZHG A;  1RAV A;  4TLJ A;  2AVI A;  5LJD A;  5HZ8 A;  1AEL A;  1H91 A;  1KT5 A;  5F7G A;  3PPT A;  2MJI A;  5FAZ A;  2CM4 A;  3BU9 A;  3FA7 A;  4YKM A;  4A8Z A;  2JN3 A;  1DZK A;  2JU8 A;  3F8A A;  1SWA A;  2X34 A;  4ZJ0 A;  1AQB A;  3FR2 A;  2N93 A;  4DNE A;  2JMB A;  3WZN A;  4GU8 A;  3SZH A;  1ALB A;  5HWZ A;  1VWB B;  2A5C A;  1VWI B;  2WR6 A;  4LZV A;  5BVQ A;  2GTL N;  5K06 A;  5B2A O;  1JMX A;  2OFA A;  3PK2 A;  2W2F A;  2EU7 X;  1SWF A;  5HTE A;  3UEU A;  3CBC A;  3U03 A;  1GT1 A;  1GX9 A;  4GJV A;  4IB6 A;  4QGW A;  4OEL A;  1IKJ A;  1BJ7 A;  1SWN A;  2OL7 A;  2ZSC A;  1SWQ A;  3B2H A;  2OY8 A;  1SY0 A;  3FA6 A;  3SAO A;  2JGS A;  1SWO A;  3PQS A;  3RE5 A;  2GH7 A;  3TGC A;  2AL0 X;  1STS B;  1JBH A;  1U0X A;  4NNS A;  2JU3 A;  2Q39 A;  5K67 A;  4Y0P A;  3WZO A;  3BLG A;  1KQX A;  2X8F A;  3FA9 A;  4O4O A;  5JD2 A;  3RDX A;  1KZX A;  3Q34 A;  1ZNG A;  3VG3 A;  5KID A;  2I5Z O;  3B2L A;  3TGA A;  1AB0 A;  4ZHC A;  4NNT A;  1TOW A;  2IFB A;  3PH5 A;  4HFO A;  4O3Y A;  1SWT A;  4D6B A;  5IO5 A;  3TZS A;  4I3C A;  3VHM A;  1BSO A;  4I6S A;  4XMD A;  5IRU A;  4O4X A;  3C78 X;  2X45 A;  4GUZ A;  4ES7 A;  2RTB B;  1YWA A;  1E06 A;  3VHI A;  3HOL A;  2KTS A;  2FTB A;  2BC3 A;  3ELX A;  3L4R A;  4O4S A;  4OEM A;  3WYQ A;  2IZF B;  1BEB A;  1MK5 A;  2MF6 A;  2QO6 A;  3VG7 A;  1G7N A;  4INN A;  3APV A;  2F09 A; 
#chains in the Genus database with same CATH homology
 2DJF A;  3PDF A;  1JQP A;  4OEM A;  4CDD A;  2DJG A;  1K3B A;  4CDC A;  4CDF A;  4OEL A;  4CDE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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