4CKKA

Apo structure of 55 kda n-terminal domain of e. coli dna gyrase a subunit
Total Genus 165
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
490
structure length
485
Chain Sequence
ALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEIT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A New Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8 Bound to DNA Gyrase Gives Fresh Insight Into the Mechanism of Inhibition.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Isomerase
molecule keywords DNA GYRASE SUBUNIT A
total genus 165
structure length 485
sequence length 490
chains with identical sequence B, C, D
ec nomenclature ec 5.99.1.3: Transferred entry: 5.6.2.3.
pdb deposition date 2014-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00521 DNA_topoisoIV DNA gyrase/topoisomerase IV, subunit A
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.268.10 Mainly Alpha Orthogonal Bundle Topoisomerase; domain 3 Topoisomerase, domain 3 4ckkA03
3.90.199.10 Alpha Beta Alpha-Beta Complex Topoisomerase II; domain 5 Topoisomerase II, domain 5 4ckkA01
4TMAA 3L4KA 3LPXA 1BGWA 3NUHA 3QX3A 1X75A 4CKKA 4Z53A 4J3NA 4CKLA 2Y3PA 4ELYA 1BJTA 2XCRB 4G0UA 4Z4QA 3L4JA 4Z3OA 4G0WA 3FOFA 2XCOA 4DDQA 2XCQA 4FM9A 1ZVUA 4ELZA 1AB4A 3FOEA 4G0VA 2RGRA
chains in the Genus database with same CATH superfamily
4TMAA 3L4KA 3LPXA 1BGWA 3NUHA 3QX3A 1X75A 4CKKA 4Z53A 4J3NA 2QPTA 4CKLA 2Y3PA 4CIDA 4ELYA 1BJTA 2XCRB 4G0UA 4Z4QA 3L4JA 4Z3OA 4G0WA 3FOFA 2XCOA 4DDQA 2XCQA 4FM9A 1ZVUA 4ELZA 1AB4A 3FOEA 4G0VA 2RGRA
chains in the Genus database with same CATH topology
4TMAA 3L4KA 3LPXA 1BGWA 3NUHA 3QX3A 1X75A 4CKKA 4Z53A 4J3NA 4CKLA 2Y3PA 4ELYA 1BJTA 2XCRB 4G0UA 4Z4QA 3L4JA 4Z3OA 4G0WA 3FOFA 2XCOA 4DDQA 2XCQA 4FM9A 1ZVUA 4ELZA 1AB4A 3FOEA 4G0VA 2RGRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TMA A;  3L4K A;  3LPX A;  1BGW A;  3NUH A;  3QX3 A;  1X75 A;  4CKK A;  4Z53 A;  4J3N A;  4CKL A;  2Y3P A;  4ELY A;  1BJT A;  2XCR B;  4G0U A;  4Z4Q A;  3L4J A;  4Z3O A;  4G0W A;  3FOF A;  2XCO A;  4DDQ A;  2XCQ A;  4FM9 A;  1ZVU A;  4ELZ A;  1AB4 A;  3FOE A;  4G0V A;  2RGR A; 
#chains in the Genus database with same CATH topology
 4TMA A;  3L4K A;  3LPX A;  1BGW A;  3NUH A;  3QX3 A;  1X75 A;  4CKK A;  4Z53 A;  4J3N A;  2QPT A;  4CKL A;  2Y3P A;  4CID A;  4ELY A;  1BJT A;  2XCR B;  4G0U A;  4Z4Q A;  3L4J A;  4Z3O A;  4G0W A;  3FOF A;  2XCO A;  4DDQ A;  2XCQ A;  4FM9 A;  1ZVU A;  4ELZ A;  1AB4 A;  3FOE A;  4G0V A;  2RGR A; 
#chains in the Genus database with same CATH homology
 4TMA A;  3L4K A;  3LPX A;  1BGW A;  3NUH A;  3QX3 A;  1X75 A;  4CKK A;  4Z53 A;  4J3N A;  4CKL A;  2Y3P A;  4ELY A;  1BJT A;  2XCR B;  4G0U A;  4Z4Q A;  3L4J A;  4Z3O A;  4G0W A;  3FOF A;  2XCO A;  4DDQ A;  2XCQ A;  4FM9 A;  1ZVU A;  4ELZ A;  1AB4 A;  3FOE A;  4G0V A;  2RGR A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...