4CKKA

Apo structure of 55 kda n-terminal domain of e. coli dna gyrase a subunit
Total Genus 165
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
165
sequence length
490
structure length
485
Chain Sequence
b'ALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEIT'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords DNA GYRASE SUBUNIT A
publication title A New Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8 Bound to DNA Gyrase Gives Fresh Insight Into the Mechanism of Inhibition.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Isomerase
total genus 165
structure length 485
sequence length 490
chains with identical sequence B, C, D
ec nomenclature ec 5.99.1.3: Transferred entry: 5.6.2.3.
pdb deposition date 2014-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00521 DNA_topoisoIV DNA gyrase/topoisomerase IV, subunit A
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.268.10 Mainly Alpha Orthogonal Bundle Topoisomerase; domain 3 Topoisomerase, domain 3 4ckkA03
3.90.199.10 Alpha Beta Alpha-Beta Complex Topoisomerase II; domain 5 Topoisomerase II, domain 5 4ckkA01
3QX3A 4J3NA 1AB4A 2XCRB 3FOEA 4TMAA 4ELZA 3LPXA 1ZVUA 1X75A 4CKKA 2XCOA 4Z4QA 3L4KA 4DDQA 4Z3OA 4G0VA 4G0UA 4FM9A 4G0WA 2Y3PA 4Z53A 4ELYA 1BJTA 4CKLA 3NUHA 3L4JA 2XCQA 3FOFA 1BGWA 2RGRA
chains in the Genus database with same CATH superfamily
3QX3A 4J3NA 1AB4A 2XCRB 3FOEA 4TMAA 4ELZA 3LPXA 2QPTA 1ZVUA 1X75A 4CKKA 2XCOA 4Z4QA 3L4KA 4DDQA 4Z3OA 4G0VA 4G0UA 4CIDA 4FM9A 4G0WA 2Y3PA 4Z53A 4ELYA 1BJTA 4CKLA 3NUHA 3L4JA 2XCQA 3FOFA 1BGWA 2RGRA
chains in the Genus database with same CATH topology
3QX3A 4J3NA 1AB4A 2XCRB 3FOEA 4TMAA 4ELZA 3LPXA 1ZVUA 1X75A 4CKKA 2XCOA 4Z4QA 3L4KA 4DDQA 4Z3OA 4G0VA 4G0UA 4FM9A 4G0WA 2Y3PA 4Z53A 4ELYA 1BJTA 4CKLA 3NUHA 3L4JA 2XCQA 3FOFA 1BGWA 2RGRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3QX3 A;  4J3N A;  1AB4 A;  2XCR B;  3FOE A;  4TMA A;  4ELZ A;  3LPX A;  1ZVU A;  1X75 A;  4CKK A;  2XCO A;  4Z4Q A;  3L4K A;  4DDQ A;  4Z3O A;  4G0V A;  4G0U A;  4FM9 A;  4G0W A;  2Y3P A;  4Z53 A;  4ELY A;  1BJT A;  4CKL A;  3NUH A;  3L4J A;  2XCQ A;  3FOF A;  1BGW A;  2RGR A; 
#chains in the Genus database with same CATH topology
 3QX3 A;  4J3N A;  1AB4 A;  2XCR B;  3FOE A;  4TMA A;  4ELZ A;  3LPX A;  2QPT A;  1ZVU A;  1X75 A;  4CKK A;  2XCO A;  4Z4Q A;  3L4K A;  4DDQ A;  4Z3O A;  4G0V A;  4G0U A;  4CID A;  4FM9 A;  4G0W A;  2Y3P A;  4Z53 A;  4ELY A;  1BJT A;  4CKL A;  3NUH A;  3L4J A;  2XCQ A;  3FOF A;  1BGW A;  2RGR A; 
#chains in the Genus database with same CATH homology
 3QX3 A;  4J3N A;  1AB4 A;  2XCR B;  3FOE A;  4TMA A;  4ELZ A;  3LPX A;  1ZVU A;  1X75 A;  4CKK A;  2XCO A;  4Z4Q A;  3L4K A;  4DDQ A;  4Z3O A;  4G0V A;  4G0U A;  4FM9 A;  4G0W A;  2Y3P A;  4Z53 A;  4ELY A;  1BJT A;  4CKL A;  3NUH A;  3L4J A;  2XCQ A;  3FOF A;  1BGW A;  2RGR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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