4CNEA

Crystal structure of e.coli trmj in complex with s-adenosyl-l- homocysteine
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
Knots found
sequence length
169
structure length
169
Chain Sequence
DPALRALQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDSQAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVAEAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAWLATQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
pubmed doi rcsb
molecule keywords TRNA (CYTIDINE/URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ
molecule tags Transferase
source organism Escherichia coli
total genus 56
structure length 169
sequence length 169
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.200: tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase.
pdb deposition date 2014-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4cneA01
4YQ0A 3N4KA 4YQRA 1O6DA 3KY7A 3ILKA 5CO4A 3NK6A 3NK7A 4J3CA 4CNDA 1X7PA 4YQKA 4YQIA 4IG6A 3ONPA 4MCBA 4CNFA 4YVKA 4YQPA 1Z85A 3L8UA 4X3MA 4CNEA 1X7OA 4YPWA 4YQOA 4CNGA 4YVGA 1GZ0A 1VH0A 4YQ2A 2CX8A 4YQ7A 1OY5A 4YPYA 4JAKA 4YVIA 4L69A 4YQDA 4YQ9A 4YQLA 1NS5A 2HA8A 4JALA 4YQ8A 2EGVA 4YQ3A 3E5YA 3IEFA 3O7BA 4XBOA 4PZKA 3KNUA 2Z0YA 3KTYA 4YQAA 4RG1A 4YVHA 4E8BA 1P9PA 2I6DA 4KGNA 1VHKA 4KDZA 5D9FA 2EGWA 4FAKA 1MXIA 4YPZA 3OINA 2QMMA 3OIJA 2V3KA 4YQ5A 4YVJA 4YPXA 4MCCA 4X3LA 1NXZA 1UALA 4YQJA 3BBHA 1UAMA 5GM8A 1V6ZA 1TO0A 5FAIA 2YY8A 4YQGA 1ZJRA 4YQSA 3OIIA 4YQ1A 3BBDA 3BBEA 4H3ZA 4YQBA 4MCDA 1UAJA 4YQ6A 3QUVA 4YQNA 3AI9X 4H3YA 3DCMX 3KW2A 3IC6A 5GMCA 1VHYA 1V2XA 3AIAA 4YQQA 1K3RA 3GYQA 4YQ4A 2V3JA 4YQCA 1UAKA 1IPAA 3N4JA 2QWVA 3AXZA 2O3AA 5GMBA 4YQTA 1J85A
chains in the Genus database with same CATH superfamily
4YQ0A 3N4KA 4YQRA 1O6DA 3KY7A 3ILKA 5CO4A 3NK6A 3NK7A 4J3CA 4CNDA 1X7PA 4YQKA 4YQIA 4IG6A 3ONPA 4MCBA 4CNFA 4YVKA 4YQPA 1Z85A 3L8UA 4X3MA 4CNEA 1X7OA 4YPWA 4YQOA 4CNGA 4YVGA 1GZ0A 1VH0A 4YQ2A 2CX8A 4YQ7A 1OY5A 4YPYA 4JAKA 4YVIA 4L69A 4YQDA 4YQ9A 4YQLA 1NS5A 2HA8A 4JALA 4YQ8A 2EGVA 4YQ3A 3E5YA 3IEFA 3O7BA 4XBOA 4PZKA 3KNUA 2Z0YA 3KTYA 4YQAA 4RG1A 4YVHA 4E8BA 1P9PA 2I6DA 4JWFA 4KGNA 1VHKA 4KDZA 5D9FA 4JWHA 2EGWA 4FAKA 1MXIA 4YPZA 3OINA 4JWGA 2QMMA 3OIJA 2V3KA 4YQ5A 4YVJA 4YPXA 4MCCA 4X3LA 1NXZA 4JWJA 1UALA 4YQJA 3BBHA 1UAMA 5GM8A 1V6ZA 1TO0A 5FAIA 2YY8A 4YQGA 1ZJRA 4YQSA 3OIIA 4YQ1A 3BBDA 3BBEA 4H3ZA 4YQBA 4MCDA 1UAJA 4YQ6A 3QUVA 4YQNA 3AI9X 4H3YA 3DCMX 3KW2A 3IC6A 5GMCA 1VHYA 1V2XA 4FMWA 3AIAA 4YQQA 1K3RA 3GYQA 4YQ4A 2V3JA 4YQCA 1UAKA 1IPAA 3N4JA 2QWVA 3AXZA 2O3AA 5GMBA 4YQTA 1J85A
chains in the Genus database with same CATH topology
4YQ0A 3N4KA 4YQRA 1O6DA 3KY7A 3ILKA 5CO4A 3NK6A 3NK7A 4J3CA 4CNDA 1X7PA 4YQKA 4YQIA 4IG6A 3ONPA 4MCBA 4CNFA 4YVKA 4YQPA 1Z85A 3L8UA 4X3MA 4CNEA 1X7OA 4YPWA 4YQOA 4CNGA 4YVGA 1GZ0A 1VH0A 4YQ2A 2CX8A 4YQ7A 1OY5A 4YPYA 4JAKA 4YVIA 4L69A 4YQDA 4YQ9A 4YQLA 1NS5A 2HA8A 4JALA 4YQ8A 2EGVA 4YQ3A 3E5YA 3IEFA 3O7BA 4XBOA 4PZKA 3KNUA 2Z0YA 3KTYA 4YQAA 4RG1A 4YVHA 4E8BA 1P9PA 2I6DA 4JWFA 4KGNA 1VHKA 4KDZA 5D9FA 4JWHA 2EGWA 4FAKA 1MXIA 4YPZA 3OINA 4JWGA 2QMMA 3OIJA 2V3KA 4YQ5A 4YVJA 4YPXA 4MCCA 4X3LA 1NXZA 4JWJA 1UALA 4YQJA 3BBHA 1UAMA 5GM8A 1V6ZA 1TO0A 5FAIA 2YY8A 4YQGA 1ZJRA 4YQSA 3OIIA 4YQ1A 3BBDA 3BBEA 4H3ZA 4YQBA 4MCDA 1UAJA 4YQ6A 3QUVA 4YQNA 3AI9X 4H3YA 3DCMX 3KW2A 3IC6A 5GMCA 1VHYA 1V2XA 4FMWA 3AIAA 4YQQA 1K3RA 3GYQA 4YQ4A 2V3JA 4YQCA 1UAKA 1IPAA 3N4JA 2QWVA 3AXZA 2O3AA 5GMBA 4YQTA 1J85A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQ0 A;  3N4K A;  4YQR A;  1O6D A;  3KY7 A;  3ILK A;  5CO4 A;  3NK6 A;  3NK7 A;  4J3C A;  4CND A;  1X7P A;  4YQK A;  4YQI A;  4IG6 A;  3ONP A;  4MCB A;  4CNF A;  4YVK A;  4YQP A;  1Z85 A;  3L8U A;  4X3M A;  4CNE A;  1X7O A;  4YPW A;  4YQO A;  4CNG A;  4YVG A;  1GZ0 A;  1VH0 A;  4YQ2 A;  2CX8 A;  4YQ7 A;  1OY5 A;  4YPY A;  4JAK A;  4YVI A;  4L69 A;  4YQD A;  4YQ9 A;  4YQL A;  1NS5 A;  2HA8 A;  4JAL A;  4YQ8 A;  2EGV A;  4YQ3 A;  3E5Y A;  3IEF A;  3O7B A;  4XBO A;  4PZK A;  3KNU A;  2Z0Y A;  3KTY A;  4YQA A;  4RG1 A;  4YVH A;  4E8B A;  1P9P A;  2I6D A;  4KGN A;  1VHK A;  4KDZ A;  5D9F A;  2EGW A;  4FAK A;  1MXI A;  4YPZ A;  3OIN A;  2QMM A;  3OIJ A;  2V3K A;  4YQ5 A;  4YVJ A;  4YPX A;  4MCC A;  4X3L A;  1NXZ A;  1UAL A;  4YQJ A;  3BBH A;  1UAM A;  5GM8 A;  1V6Z A;  1TO0 A;  5FAI A;  2YY8 A;  4YQG A;  1ZJR A;  4YQS A;  3OII A;  4YQ1 A;  3BBD A;  3BBE A;  4H3Z A;  4YQB A;  4MCD A;  1UAJ A;  4YQ6 A;  3QUV A;  4YQN A;  3AI9 X;  4H3Y A;  3DCM X;  3KW2 A;  3IC6 A;  5GMC A;  1VHY A;  1V2X A;  3AIA A;  4YQQ A;  1K3R A;  3GYQ A;  4YQ4 A;  2V3J A;  4YQC A;  1UAK A;  1IPA A;  3N4J A;  2QWV A;  3AXZ A;  2O3A A;  5GMB A;  4YQT A;  1J85 A; 
#chains in the Genus database with same CATH topology
 4YQ0 A;  3N4K A;  4YQR A;  1O6D A;  3KY7 A;  3ILK A;  5CO4 A;  3NK6 A;  3NK7 A;  4J3C A;  4CND A;  1X7P A;  4YQK A;  4YQI A;  4IG6 A;  3ONP A;  4MCB A;  4CNF A;  4YVK A;  4YQP A;  1Z85 A;  3L8U A;  4X3M A;  4CNE A;  1X7O A;  4YPW A;  4YQO A;  4CNG A;  4YVG A;  1GZ0 A;  1VH0 A;  4YQ2 A;  2CX8 A;  4YQ7 A;  1OY5 A;  4YPY A;  4JAK A;  4YVI A;  4L69 A;  4YQD A;  4YQ9 A;  4YQL A;  1NS5 A;  2HA8 A;  4JAL A;  4YQ8 A;  2EGV A;  4YQ3 A;  3E5Y A;  3IEF A;  3O7B A;  4XBO A;  4PZK A;  3KNU A;  2Z0Y A;  3KTY A;  4YQA A;  4RG1 A;  4YVH A;  4E8B A;  1P9P A;  2I6D A;  4JWF A;  4KGN A;  1VHK A;  4KDZ A;  5D9F A;  4JWH A;  2EGW A;  4FAK A;  1MXI A;  4YPZ A;  3OIN A;  4JWG A;  2QMM A;  3OIJ A;  2V3K A;  4YQ5 A;  4YVJ A;  4YPX A;  4MCC A;  4X3L A;  1NXZ A;  4JWJ A;  1UAL A;  4YQJ A;  3BBH A;  1UAM A;  5GM8 A;  1V6Z A;  1TO0 A;  5FAI A;  2YY8 A;  4YQG A;  1ZJR A;  4YQS A;  3OII A;  4YQ1 A;  3BBD A;  3BBE A;  4H3Z A;  4YQB A;  4MCD A;  1UAJ A;  4YQ6 A;  3QUV A;  4YQN A;  3AI9 X;  4H3Y A;  3DCM X;  3KW2 A;  3IC6 A;  5GMC A;  1VHY A;  1V2X A;  4FMW A;  3AIA A;  4YQQ A;  1K3R A;  3GYQ A;  4YQ4 A;  2V3J A;  4YQC A;  1UAK A;  1IPA A;  3N4J A;  2QWV A;  3AXZ A;  2O3A A;  5GMB A;  4YQT A;  1J85 A; 
#chains in the Genus database with same CATH homology
 4YQ0 A;  3N4K A;  4YQR A;  1O6D A;  3KY7 A;  3ILK A;  5CO4 A;  3NK6 A;  3NK7 A;  4J3C A;  4CND A;  1X7P A;  4YQK A;  4YQI A;  4IG6 A;  3ONP A;  4MCB A;  4CNF A;  4YVK A;  4YQP A;  1Z85 A;  3L8U A;  4X3M A;  4CNE A;  1X7O A;  4YPW A;  4YQO A;  4CNG A;  4YVG A;  1GZ0 A;  1VH0 A;  4YQ2 A;  2CX8 A;  4YQ7 A;  1OY5 A;  4YPY A;  4JAK A;  4YVI A;  4L69 A;  4YQD A;  4YQ9 A;  4YQL A;  1NS5 A;  2HA8 A;  4JAL A;  4YQ8 A;  2EGV A;  4YQ3 A;  3E5Y A;  3IEF A;  3O7B A;  4XBO A;  4PZK A;  3KNU A;  2Z0Y A;  3KTY A;  4YQA A;  4RG1 A;  4YVH A;  4E8B A;  1P9P A;  2I6D A;  4JWF A;  4KGN A;  1VHK A;  4KDZ A;  5D9F A;  4JWH A;  2EGW A;  4FAK A;  1MXI A;  4YPZ A;  3OIN A;  4JWG A;  2QMM A;  3OIJ A;  2V3K A;  4YQ5 A;  4YVJ A;  4YPX A;  4MCC A;  4X3L A;  1NXZ A;  4JWJ A;  1UAL A;  4YQJ A;  3BBH A;  1UAM A;  5GM8 A;  1V6Z A;  1TO0 A;  5FAI A;  2YY8 A;  4YQG A;  1ZJR A;  4YQS A;  3OII A;  4YQ1 A;  3BBD A;  3BBE A;  4H3Z A;  4YQB A;  4MCD A;  1UAJ A;  4YQ6 A;  3QUV A;  4YQN A;  3AI9 X;  4H3Y A;  3DCM X;  3KW2 A;  3IC6 A;  5GMC A;  1VHY A;  1V2X A;  4FMW A;  3AIA A;  4YQQ A;  1K3R A;  3GYQ A;  4YQ4 A;  2V3J A;  4YQC A;  1UAK A;  1IPA A;  3N4J A;  2QWV A;  3AXZ A;  2O3A A;  5GMB A;  4YQT A;  1J85 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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