4CNGA

Crystal structure of sulfolobus acidocaldarius trmj in complex with s-adenosyl-l-homocysteine
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
Knots found
sequence length
156
structure length
156
Chain Sequence
MTIRLVIVEPEGAYNLGFIARLVKNFLIDEFYVVNPKADINEAIKFSAKGSEVIEKMMKITNNFDDAIRDVDLKIATSSIADIKGDLLRKSIRPIDLERLIKDKKVAFIFGRESVGLTREEIAKSDFLLFIPANPEYPVLNLSHAVGIVLYELWRN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
pubmed doi rcsb
molecule tags Transferase
source organism Sulfolobus acidocaldarius
molecule keywords SPOU RRNA METHYLASE
total genus 51
structure length 156
sequence length 156
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.200: tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase.
pdb deposition date 2014-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4cngA00
3KW2A 4YQ9A 4MCDA 4YVIA 4MCCA 1V6ZA 4YQ3A 4XBOA 4YVHA 1VH0A 2QMMA 3QUVA 4YPWA 4YPXA 4YQCA 5CO4A 4YPYA 4YQ2A 2CX8A 4YQ1A 1GZ0A 3ONPA 1J85A 4JALA 4E8BA 4MCBA 5GMCA 4YQ7A 4CNEA 4YQNA 2QWVA 4YQDA 1ZJRA 4YQLA 1O6DA 2V3KA 4YQ8A 5GMBA 1NXZA 1MXIA 2V3JA 4KDZA 5FAIA 4YQPA 2I6DA 3NK7A 4RG1A 1X7PA 4YQKA 2HA8A 3GYQA 4YQOA 3OINA 4YQ0A 4YQTA 2YY8A 2EGVA 3DCMX 3BBEA 4YQQA 2Z0YA 4YQIA 3ILKA 4YQJA 3AXZA 4YQAA 1UALA 3OIIA 4PZKA 3E5YA 4L69A 1V2XA 1Z85A 1UAJA 3NK6A 4J3CA 1OY5A 1K3RA 4YVJA 3N4KA 4X3LA 3BBHA 1VHKA 4H3YA 1TO0A 4YQBA 4H3ZA 1NS5A 4FAKA 4YQSA 4YPZA 1UAMA 4CNDA 1VHYA 4YVGA 3KTYA 4X3MA 1IPAA 4IG6A 3BBDA 1X7OA 4YQ4A 4CNGA 3KNUA 3O7BA 3L8UA 4CNFA 4KGNA 4YQ5A 4YQ6A 3AI9X 5D9FA 1P9PA 2EGWA 4YVKA 3AIAA 2O3AA 3IEFA 4JAKA 1UAKA 5GM8A 3IC6A 3N4JA 4YQRA 3KY7A 3OIJA 4YQGA
chains in the Genus database with same CATH superfamily
3KW2A 4YQ9A 4MCDA 4YVIA 4MCCA 1V6ZA 4YQ3A 4XBOA 4YVHA 1VH0A 2QMMA 3QUVA 4YPWA 4YPXA 4YQCA 5CO4A 4YPYA 4YQ2A 2CX8A 4YQ1A 1GZ0A 3ONPA 1J85A 4JALA 4E8BA 4MCBA 5GMCA 4YQ7A 4CNEA 4YQNA 2QWVA 4YQDA 1ZJRA 4YQLA 1O6DA 2V3KA 4YQ8A 5GMBA 1NXZA 1MXIA 2V3JA 4KDZA 5FAIA 4YQPA 2I6DA 3NK7A 4RG1A 1X7PA 4YQKA 2HA8A 3GYQA 4YQOA 3OINA 4YQ0A 4YQTA 4JWHA 2YY8A 2EGVA 3DCMX 3BBEA 4YQQA 2Z0YA 4YQIA 3ILKA 4YQJA 3AXZA 4YQAA 1UALA 3OIIA 4PZKA 3E5YA 4L69A 4JWFA 1V2XA 1Z85A 1UAJA 4JWGA 3NK6A 4J3CA 1OY5A 1K3RA 4YVJA 3N4KA 4JWJA 4X3LA 3BBHA 1VHKA 4H3YA 1TO0A 4YQBA 4H3ZA 1NS5A 4FAKA 4YQSA 4YPZA 1UAMA 4CNDA 1VHYA 4YVGA 3KTYA 4X3MA 1IPAA 4IG6A 3BBDA 1X7OA 4YQ4A 4CNGA 3KNUA 3O7BA 3L8UA 4CNFA 4KGNA 4YQ5A 4YQ6A 3AI9X 5D9FA 1P9PA 2EGWA 4YVKA 3AIAA 2O3AA 3IEFA 4JAKA 1UAKA 4FMWA 5GM8A 3IC6A 3N4JA 4YQRA 3KY7A 3OIJA 4YQGA
chains in the Genus database with same CATH topology
3KW2A 4YQ9A 4MCDA 4YVIA 4MCCA 1V6ZA 4YQ3A 4XBOA 4YVHA 1VH0A 2QMMA 3QUVA 4YPWA 4YPXA 4YQCA 5CO4A 4YPYA 4YQ2A 2CX8A 4YQ1A 1GZ0A 3ONPA 1J85A 4JALA 4E8BA 4MCBA 5GMCA 4YQ7A 4CNEA 4YQNA 2QWVA 4YQDA 1ZJRA 4YQLA 1O6DA 2V3KA 4YQ8A 5GMBA 1NXZA 1MXIA 2V3JA 4KDZA 5FAIA 4YQPA 2I6DA 3NK7A 4RG1A 1X7PA 4YQKA 2HA8A 3GYQA 4YQOA 3OINA 4YQ0A 4YQTA 4JWHA 2YY8A 2EGVA 3DCMX 3BBEA 4YQQA 2Z0YA 4YQIA 3ILKA 4YQJA 3AXZA 4YQAA 1UALA 3OIIA 4PZKA 3E5YA 4L69A 4JWFA 1V2XA 1Z85A 1UAJA 4JWGA 3NK6A 4J3CA 1OY5A 1K3RA 4YVJA 3N4KA 4JWJA 4X3LA 3BBHA 1VHKA 4H3YA 1TO0A 4YQBA 4H3ZA 1NS5A 4FAKA 4YQSA 4YPZA 1UAMA 4CNDA 1VHYA 4YVGA 3KTYA 4X3MA 1IPAA 4IG6A 3BBDA 1X7OA 4YQ4A 4CNGA 3KNUA 3O7BA 3L8UA 4CNFA 4KGNA 4YQ5A 4YQ6A 3AI9X 5D9FA 1P9PA 2EGWA 4YVKA 3AIAA 2O3AA 3IEFA 4JAKA 1UAKA 4FMWA 5GM8A 3IC6A 3N4JA 4YQRA 3KY7A 3OIJA 4YQGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KW2 A;  4YQ9 A;  4MCD A;  4YVI A;  4MCC A;  1V6Z A;  4YQ3 A;  4XBO A;  4YVH A;  1VH0 A;  2QMM A;  3QUV A;  4YPW A;  4YPX A;  4YQC A;  5CO4 A;  4YPY A;  4YQ2 A;  2CX8 A;  4YQ1 A;  1GZ0 A;  3ONP A;  1J85 A;  4JAL A;  4E8B A;  4MCB A;  5GMC A;  4YQ7 A;  4CNE A;  4YQN A;  2QWV A;  4YQD A;  1ZJR A;  4YQL A;  1O6D A;  2V3K A;  4YQ8 A;  5GMB A;  1NXZ A;  1MXI A;  2V3J A;  4KDZ A;  5FAI A;  4YQP A;  2I6D A;  3NK7 A;  4RG1 A;  1X7P A;  4YQK A;  2HA8 A;  3GYQ A;  4YQO A;  3OIN A;  4YQ0 A;  4YQT A;  2YY8 A;  2EGV A;  3DCM X;  3BBE A;  4YQQ A;  2Z0Y A;  4YQI A;  3ILK A;  4YQJ A;  3AXZ A;  4YQA A;  1UAL A;  3OII A;  4PZK A;  3E5Y A;  4L69 A;  1V2X A;  1Z85 A;  1UAJ A;  3NK6 A;  4J3C A;  1OY5 A;  1K3R A;  4YVJ A;  3N4K A;  4X3L A;  3BBH A;  1VHK A;  4H3Y A;  1TO0 A;  4YQB A;  4H3Z A;  1NS5 A;  4FAK A;  4YQS A;  4YPZ A;  1UAM A;  4CND A;  1VHY A;  4YVG A;  3KTY A;  4X3M A;  1IPA A;  4IG6 A;  3BBD A;  1X7O A;  4YQ4 A;  4CNG A;  3KNU A;  3O7B A;  3L8U A;  4CNF A;  4KGN A;  4YQ5 A;  4YQ6 A;  3AI9 X;  5D9F A;  1P9P A;  2EGW A;  4YVK A;  3AIA A;  2O3A A;  3IEF A;  4JAK A;  1UAK A;  5GM8 A;  3IC6 A;  3N4J A;  4YQR A;  3KY7 A;  3OIJ A;  4YQG A; 
#chains in the Genus database with same CATH topology
 3KW2 A;  4YQ9 A;  4MCD A;  4YVI A;  4MCC A;  1V6Z A;  4YQ3 A;  4XBO A;  4YVH A;  1VH0 A;  2QMM A;  3QUV A;  4YPW A;  4YPX A;  4YQC A;  5CO4 A;  4YPY A;  4YQ2 A;  2CX8 A;  4YQ1 A;  1GZ0 A;  3ONP A;  1J85 A;  4JAL A;  4E8B A;  4MCB A;  5GMC A;  4YQ7 A;  4CNE A;  4YQN A;  2QWV A;  4YQD A;  1ZJR A;  4YQL A;  1O6D A;  2V3K A;  4YQ8 A;  5GMB A;  1NXZ A;  1MXI A;  2V3J A;  4KDZ A;  5FAI A;  4YQP A;  2I6D A;  3NK7 A;  4RG1 A;  1X7P A;  4YQK A;  2HA8 A;  3GYQ A;  4YQO A;  3OIN A;  4YQ0 A;  4YQT A;  4JWH A;  2YY8 A;  2EGV A;  3DCM X;  3BBE A;  4YQQ A;  2Z0Y A;  4YQI A;  3ILK A;  4YQJ A;  3AXZ A;  4YQA A;  1UAL A;  3OII A;  4PZK A;  3E5Y A;  4L69 A;  4JWF A;  1V2X A;  1Z85 A;  1UAJ A;  4JWG A;  3NK6 A;  4J3C A;  1OY5 A;  1K3R A;  4YVJ A;  3N4K A;  4JWJ A;  4X3L A;  3BBH A;  1VHK A;  4H3Y A;  1TO0 A;  4YQB A;  4H3Z A;  1NS5 A;  4FAK A;  4YQS A;  4YPZ A;  1UAM A;  4CND A;  1VHY A;  4YVG A;  3KTY A;  4X3M A;  1IPA A;  4IG6 A;  3BBD A;  1X7O A;  4YQ4 A;  4CNG A;  3KNU A;  3O7B A;  3L8U A;  4CNF A;  4KGN A;  4YQ5 A;  4YQ6 A;  3AI9 X;  5D9F A;  1P9P A;  2EGW A;  4YVK A;  3AIA A;  2O3A A;  3IEF A;  4JAK A;  1UAK A;  4FMW A;  5GM8 A;  3IC6 A;  3N4J A;  4YQR A;  3KY7 A;  3OIJ A;  4YQG A; 
#chains in the Genus database with same CATH homology
 3KW2 A;  4YQ9 A;  4MCD A;  4YVI A;  4MCC A;  1V6Z A;  4YQ3 A;  4XBO A;  4YVH A;  1VH0 A;  2QMM A;  3QUV A;  4YPW A;  4YPX A;  4YQC A;  5CO4 A;  4YPY A;  4YQ2 A;  2CX8 A;  4YQ1 A;  1GZ0 A;  3ONP A;  1J85 A;  4JAL A;  4E8B A;  4MCB A;  5GMC A;  4YQ7 A;  4CNE A;  4YQN A;  2QWV A;  4YQD A;  1ZJR A;  4YQL A;  1O6D A;  2V3K A;  4YQ8 A;  5GMB A;  1NXZ A;  1MXI A;  2V3J A;  4KDZ A;  5FAI A;  4YQP A;  2I6D A;  3NK7 A;  4RG1 A;  1X7P A;  4YQK A;  2HA8 A;  3GYQ A;  4YQO A;  3OIN A;  4YQ0 A;  4YQT A;  4JWH A;  2YY8 A;  2EGV A;  3DCM X;  3BBE A;  4YQQ A;  2Z0Y A;  4YQI A;  3ILK A;  4YQJ A;  3AXZ A;  4YQA A;  1UAL A;  3OII A;  4PZK A;  3E5Y A;  4L69 A;  4JWF A;  1V2X A;  1Z85 A;  1UAJ A;  4JWG A;  3NK6 A;  4J3C A;  1OY5 A;  1K3R A;  4YVJ A;  3N4K A;  4JWJ A;  4X3L A;  3BBH A;  1VHK A;  4H3Y A;  1TO0 A;  4YQB A;  4H3Z A;  1NS5 A;  4FAK A;  4YQS A;  4YPZ A;  1UAM A;  4CND A;  1VHY A;  4YVG A;  3KTY A;  4X3M A;  1IPA A;  4IG6 A;  3BBD A;  1X7O A;  4YQ4 A;  4CNG A;  3KNU A;  3O7B A;  3L8U A;  4CNF A;  4KGN A;  4YQ5 A;  4YQ6 A;  3AI9 X;  5D9F A;  1P9P A;  2EGW A;  4YVK A;  3AIA A;  2O3A A;  3IEF A;  4JAK A;  1UAK A;  4FMW A;  5GM8 A;  3IC6 A;  3N4J A;  4YQR A;  3KY7 A;  3OIJ A;  4YQG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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