4D2BA

Structure of a ligand free pot family peptide transporter
Total Genus 176
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
176
sequence length
467
structure length
445
Chain Sequence
KTFFGQPLGLSTLFMTEMWERFSYYGMRAILLYYMWFLISTGDLHITRATAASIMAIYASMVYLSGTIGGFVADRIIGARPAVFWGGVLIMLGHIVLALPFGASALFGSIILIIIGTGFLKPNVSTLVGTLYDEHDRRRDAGFSIFVFGINLGAFIAPLIVGAAQEAAGYHVAFSLAAIGMFIGLLVYYFGGKKTLDPHYLRPTDPLAPEEVKPLLVKVSLAVAGFIAIIVVMNLVGWNSLPAYINLLTIVAIAIPVFYFAWMISLRVVSYIPLFIAAVLFWAIEEQGSVVLATFAAERVDSSWFPVSWFQSLNPLFIMLYTPFFAWLWTANQPSSPTKFAVGLMFAGLSFLLMAIPGALYGTSGKVSPLWLVGSWALVILGEMLISPVGLSVTTMMSMWFLSSSVGSALNAQLVTLYNAKSEVAYFSYFGLGSVVLGIVLVFLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
pubmed doi rcsb
molecule keywords DI-OR TRIPEPTIDE\:H+ SYMPORTER
molecule tags Transport protein
source organism Streptococcus thermophilus
total genus 176
structure length 445
sequence length 467
ec nomenclature
pdb deposition date 2014-05-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00854 PTR2 POT family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4d2bA00
3O7PA 4OAAA 2XUTA 1PW4A 4YBQA 4PYPA 4XNJA 2CFPA 4GBYA 4APSA 2V8NA 4ZWBA 4JA3A 4W6VA 4UVMA 4YB9D 4IU8A 5D6KA 5GXBA 1PV6A 4Q65A 5EQGA 4IU9A 4U4WA 4ZW9A 5A2OA 4IKZA 4TPGA 4D2BA 5D59A 4JREA 5D58A 4U4VA 2Y5YA 4XNIA 4IKVA 3WDOA 1PV7A 4GC0A 4LDSA 4U4TA 2CFQA 4GBZA 4IKXA 4ZYRA 4QIQA 5C65A 4OH3A 5A2NA 4ZWCA 4LEPA 4IKYA 4D2CA 3O7QA 4D2DA 4TPHA 5EQHA 4IKWA 5EQIA 4JR9A 4TPJA 4J05A
chains in the Genus database with same CATH superfamily
1Y1VD 2ILKA 1EERA 4W6VA 3QT2C 1VLKA 1BP3A 1YKBA 3BPNA 4NKQC 1M4RA 3LB6A 5IYBD 3WDOA 1PV7A 3D87A 1F45B 2R93D 5FHXA 3HOUD 1IK0A 2B8ZA 3NCBA 2PSMA 5D71A 1Y14A 2JA8D 1CYLA 1M4BA 4YDYI 1EKUA 4GS7A 1Y6ML 4A3CD 3D48P 1M49A 1KF9A 2VUMD 1ALUA 5C44D 5D58A 3DI2A 4ZWCA 4PS4A 1ITLA 3EW3A 4JR9A 1GA3A 1HIJA 3O7PA 4OAAA 4YBQA 2O6IA 4GRWA 1M48A 4ZWBA 3HHRA 1P9MB 4A3KD 2ERJD 1SCFA 1RFBA 1HWGA 3I4ND 4YPGC 3MZGA 3DI3A 4EXPA 3L5XA 3L5WI 5EQGA 1AXIA 4YQXA 1ITMA 1F6FA 2B8XA 1ILKA 3HMXB 4JA3A 5FLMD 1FYHA 2D48A 1PVHB 5D6KA 5GXBA 4DOHA 4IU9A 3QB7A 4TPGA 3SE4B 4BY1D 1GNCA 1PW6A 1CD9A 1Z7CA 2B8UA 1AX8A 4BBSD 4A3JD 4A3LD 2XUTA 4PYPA 4UVMA 4YB9D 4IU8A 1Y1WD 2INTA 1A7MA 2LAGA 5IP9D 4IKZA 3UX9A 4D2BA 1D9CA 4JREA 3D85C 4U4VA 5LQBA 4A3MD 1PY2A 3OQ3A 4GC0A 2O26A 1EVSA 2B90A 3QAZA 3BPLA 1EMRA 3SE3B 3HOWD 4A93D 4A3ID 3N0PA 1CN4C 4APSA 1IL6A 4NEMA 5TS9A 1I1RB 2B63D 4O6KA 5D70A 4LDSA 1LKIA 3NCCA 4QIQA 4CNIC 5A2NA 5IP7D 3H0GD 3TGXB 2L3YA 3G6DA 3BESL 1IRLA 2JA6D 2H24A 4A3BD 1IJZA 5D28B 5D59A 3S9DA 2B5IA 2CYKA 4DKDA 2Q14A 5C3ED 1RW5A 4EXNA 5FUCA 5EQHA 3HOVD 4IKWA 4TPJA 4NEJA 1INRA 4NN5A 2XQBA 1HWHA 3QWRB 2O27A 5A2OA 2Y5YA 1Y6NL 4LEPA 4IKYA 4D2CA 1ITFA 5D22A 1IARA 4FA8E 5EQIA 3LB6B 1HUWA 3IRHA 1PW4A 4NN6A 3NPZA 4A3FD 2IL6A 1Y6KL 1JLIA 2Z3QA 3B5KA 1A22A 1J7VL 4IKXA 1RCBA 4J4LC 4D2DA 1HGUA 1B5LA 2C35A 2Q7NB 3INKC 3PO2D 1NBPA 5IYCD 5C7XA 2Z3RA 2JA5D 1LK3A 1M47A 1HZIA 4IKVA 4DKFA 2OQPA 1ITIA 3O7QA 4J05A 1BBNA 4LRLA 3Q1SI 3UF2A 3PIVA 1PGRA 3BPOA 1M4CA 5KNHI 4BXXD 1AU1A 3HOYD 5IYDD 4XNIA 4ZYRA 1QVNA 4OH3A 2Q98A 4I77Z 4A3ED 3NCEA 4DKEA 1CNT1 4BBRD 4GBYA 1BGDA 3OG4A 3VA2A 4A3DD 1HIKA 4X51A 2LMSA 1Z92A 2E9WC 4U4TA 2JA7D 1M4AA 4TPHA 1BGCA 5C4XD 4BY7D 1FG9A 4Z5RD 1EXZA 1N1FA 2D9QA 1ETEA 2B8YA 2CFPA 3DLQI 3NCFA 1RHGA 4WRLB 4O9HA 4ZW9A 2L3OA 5E4EA 1V7MV 3N06A 3PIWA 4GBZA 5C65A 4ZF7A 4NI7A 3WCYI 1BGEA 2R92D 3H3VE 3G9VB 3OG6A 4YUEC 2V8NA 4DKCA 3UEZE 3PO3D 4NN7A 1BCNA 4U4WA 2GMFA 1LQSL 3EJJA 4MHLA 2R7ZD 3I4MD 3HOZD 2HYMB 2KZ1A 3HOXD 3HHCA 4RS1A 4ZS7A 4A3GD 4XNJA 1WU3I 4NI9A 1WCMD 3AYHA 1CSGA 3QB1A 1BUYA 1PV6A 4Q65A 5L6YC 1HULA 2B91A 1D9GA 3FKID 3DUHC 2CFQA 1V7NV 5D72A 3UF5A 3DGCL
chains in the Genus database with same CATH topology
3O7PA 4OAAA 2XUTA 1PW4A 4YBQA 4PYPA 4XNJA 2CFPA 4GBYA 4APSA 2V8NA 4ZWBA 4JA3A 4W6VA 4UVMA 4YB9D 4IU8A 5D6KA 5GXBA 1PV6A 4Q65A 5EQGA 4IU9A 4U4WA 4ZW9A 5A2OA 4IKZA 4TPGA 4D2BA 5D59A 4JREA 5D58A 4U4VA 2Y5YA 4XNIA 4IKVA 3WDOA 1PV7A 4GC0A 4LDSA 4U4TA 2CFQA 4GBZA 4IKXA 4ZYRA 4QIQA 5C65A 4OH3A 5A2NA 4ZWCA 4LEPA 4IKYA 4D2CA 3O7QA 4D2DA 4TPHA 5EQHA 4IKWA 5EQIA 4JR9A 4TPJA 4J05A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3O7P A;  4OAA A;  2XUT A;  1PW4 A;  4YBQ A;  4PYP A;  4XNJ A;  2CFP A;  4GBY A;  4APS A;  2V8N A;  4ZWB A;  4JA3 A;  4W6V A;  4UVM A;  4YB9 D;  4IU8 A;  5D6K A;  5GXB A;  1PV6 A;  4Q65 A;  5EQG A;  4IU9 A;  4U4W A;  4ZW9 A;  5A2O A;  4IKZ A;  4TPG A;  4D2B A;  5D59 A;  4JRE A;  5D58 A;  4U4V A;  2Y5Y A;  4XNI A;  4IKV A;  3WDO A;  1PV7 A;  4GC0 A;  4LDS A;  4U4T A;  2CFQ A;  4GBZ A;  4IKX A;  4ZYR A;  4QIQ A;  5C65 A;  4OH3 A;  5A2N A;  4ZWC A;  4LEP A;  4IKY A;  4D2C A;  3O7Q A;  4D2D A;  4TPH A;  5EQH A;  4IKW A;  5EQI A;  4JR9 A;  4TPJ A;  4J05 A; 
#chains in the Genus database with same CATH topology
 1Y1V D;  2ILK A;  1EER A;  4W6V A;  3QT2 C;  1VLK A;  1BP3 A;  1YKB A;  3BPN A;  4NKQ C;  1M4R A;  3LB6 A;  5IYB D;  3WDO A;  1PV7 A;  3D87 A;  1F45 B;  2R93 D;  5FHX A;  3HOU D;  1IK0 A;  2B8Z A;  3NCB A;  2PSM A;  5D71 A;  1Y14 A;  2JA8 D;  1CYL A;  1M4B A;  4YDY I;  1EKU A;  4GS7 A;  1Y6M L;  4A3C D;  3D48 P;  1M49 A;  1KF9 A;  2VUM D;  1ALU A;  5C44 D;  5D58 A;  3DI2 A;  4ZWC A;  4PS4 A;  1ITL A;  3EW3 A;  4JR9 A;  1GA3 A;  1HIJ A;  3O7P A;  4OAA A;  4YBQ A;  2O6I A;  4GRW A;  1M48 A;  4ZWB A;  3HHR A;  1P9M B;  4A3K D;  2ERJ D;  1SCF A;  1RFB A;  1HWG A;  3I4N D;  4YPG C;  3MZG A;  3DI3 A;  4EXP A;  3L5X A;  3L5W I;  5EQG A;  1AXI A;  4YQX A;  1ITM A;  1F6F A;  2B8X A;  1ILK A;  3HMX B;  4JA3 A;  5FLM D;  1FYH A;  2D48 A;  1PVH B;  5D6K A;  5GXB A;  4DOH A;  4IU9 A;  3QB7 A;  4TPG A;  3SE4 B;  4BY1 D;  1GNC A;  1PW6 A;  1CD9 A;  1Z7C A;  2B8U A;  1AX8 A;  4BBS D;  4A3J D;  4A3L D;  2XUT A;  4PYP A;  4UVM A;  4YB9 D;  4IU8 A;  1Y1W D;  2INT A;  1A7M A;  2LAG A;  5IP9 D;  4IKZ A;  3UX9 A;  4D2B A;  1D9C A;  4JRE A;  3D85 C;  4U4V A;  5LQB A;  4A3M D;  1PY2 A;  3OQ3 A;  4GC0 A;  2O26 A;  1EVS A;  2B90 A;  3QAZ A;  3BPL A;  1EMR A;  3SE3 B;  3HOW D;  4A93 D;  4A3I D;  3N0P A;  1CN4 C;  4APS A;  1IL6 A;  4NEM A;  5TS9 A;  1I1R B;  2B63 D;  4O6K A;  5D70 A;  4LDS A;  1LKI A;  3NCC A;  4QIQ A;  4CNI C;  5A2N A;  5IP7 D;  3H0G D;  3TGX B;  2L3Y A;  3G6D A;  3BES L;  1IRL A;  2JA6 D;  2H24 A;  4A3B D;  1IJZ A;  5D28 B;  5D59 A;  3S9D A;  2B5I A;  2CYK A;  4DKD A;  2Q14 A;  5C3E D;  1RW5 A;  4EXN A;  5FUC A;  5EQH A;  3HOV D;  4IKW A;  4TPJ A;  4NEJ A;  1INR A;  4NN5 A;  2XQB A;  1HWH A;  3QWR B;  2O27 A;  5A2O A;  2Y5Y A;  1Y6N L;  4LEP A;  4IKY A;  4D2C A;  1ITF A;  5D22 A;  1IAR A;  4FA8 E;  5EQI A;  3LB6 B;  1HUW A;  3IRH A;  1PW4 A;  4NN6 A;  3NPZ A;  4A3F D;  2IL6 A;  1Y6K L;  1JLI A;  2Z3Q A;  3B5K A;  1A22 A;  1J7V L;  4IKX A;  1RCB A;  4J4L C;  4D2D A;  1HGU A;  1B5L A;  2C35 A;  2Q7N B;  3INK C;  3PO2 D;  1NBP A;  5IYC D;  5C7X A;  2Z3R A;  2JA5 D;  1LK3 A;  1M47 A;  1HZI A;  4IKV A;  4DKF A;  2OQP A;  1ITI A;  3O7Q A;  4J05 A;  1BBN A;  4LRL A;  3Q1S I;  3UF2 A;  3PIV A;  1PGR A;  3BPO A;  1M4C A;  5KNH I;  4BXX D;  1AU1 A;  3HOY D;  5IYD D;  4XNI A;  4ZYR A;  1QVN A;  4OH3 A;  2Q98 A;  4I77 Z;  4A3E D;  3NCE A;  4DKE A;  1CNT 1;  4BBR D;  4GBY A;  1BGD A;  3OG4 A;  3VA2 A;  4A3D D;  1HIK A;  4X51 A;  2LMS A;  1Z92 A;  2E9W C;  4U4T A;  2JA7 D;  1M4A A;  4TPH A;  1BGC A;  5C4X D;  4BY7 D;  1FG9 A;  4Z5R D;  1EXZ A;  1N1F A;  2D9Q A;  1ETE A;  2B8Y A;  2CFP A;  3DLQ I;  3NCF A;  1RHG A;  4WRL B;  4O9H A;  4ZW9 A;  2L3O A;  5E4E A;  1V7M V;  3N06 A;  3PIW A;  4GBZ A;  5C65 A;  4ZF7 A;  4NI7 A;  3WCY I;  1BGE A;  2R92 D;  3H3V E;  3G9V B;  3OG6 A;  4YUE C;  2V8N A;  4DKC A;  3UEZ E;  3PO3 D;  4NN7 A;  1BCN A;  4U4W A;  2GMF A;  1LQS L;  3EJJ A;  4MHL A;  2R7Z D;  3I4M D;  3HOZ D;  2HYM B;  2KZ1 A;  3HOX D;  3HHC A;  4RS1 A;  4ZS7 A;  4A3G D;  4XNJ A;  1WU3 I;  4NI9 A;  1WCM D;  3AYH A;  1CSG A;  3QB1 A;  1BUY A;  1PV6 A;  4Q65 A;  5L6Y C;  1HUL A;  2B91 A;  1D9G A;  3FKI D;  3DUH C;  2CFQ A;  1V7N V;  5D72 A;  3UF5 A;  3DGC L; 
#chains in the Genus database with same CATH homology
 3O7P A;  4OAA A;  2XUT A;  1PW4 A;  4YBQ A;  4PYP A;  4XNJ A;  2CFP A;  4GBY A;  4APS A;  2V8N A;  4ZWB A;  4JA3 A;  4W6V A;  4UVM A;  4YB9 D;  4IU8 A;  5D6K A;  5GXB A;  1PV6 A;  4Q65 A;  5EQG A;  4IU9 A;  4U4W A;  4ZW9 A;  5A2O A;  4IKZ A;  4TPG A;  4D2B A;  5D59 A;  4JRE A;  5D58 A;  4U4V A;  2Y5Y A;  4XNI A;  4IKV A;  3WDO A;  1PV7 A;  4GC0 A;  4LDS A;  4U4T A;  2CFQ A;  4GBZ A;  4IKX A;  4ZYR A;  4QIQ A;  5C65 A;  4OH3 A;  5A2N A;  4ZWC A;  4LEP A;  4IKY A;  4D2C A;  3O7Q A;  4D2D A;  4TPH A;  5EQH A;  4IKW A;  5EQI A;  4JR9 A;  4TPJ A;  4J05 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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