4D52A

Crystal structure of fucose binding lectin from aspergillus fumigatus (afl) in complex with l-galactopyranose.
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
314
structure length
314
Chain Sequence
STPGAQQVLFRTGIAAVNSTNHLRVYFQDVYGSIRESLYEGSWANGTEKNVIGNAKLGSPVAATSKELKHIRVYTLTEGNTLQEFAYDSGTGWYNGGLGGAKFQVAPYSCIAAVFLAGTDALQLRIYAQKPDNTIQEYMWNGDGWKEGTNLGGALPGTGIGATSFRYTDYNGPSIRIWFQTDDLKLVQRAYDPHKGWYPDLVTIFDRAPPRTAIAATSFGAGNSSIYMRIYFVNSDNTIWQVCWDHGKGYHDKGTITPVIQGSEVAIISWGSFANNGPDLRLYFQNGTYISAVSEWVWNRAHGSQLGRSALPPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into Aspergillus Fumigatus Lectin Specificity: Afl Binding Sites are Functionally Non-Equivalent.
pubmed doi rcsb
molecule keywords FUCOSE-SPECIFIC LECTIN FLEA
molecule tags Sugar binding protein
source organism Aspergillus fumigatus
total genus 79
structure length 314
sequence length 314
ec nomenclature
pdb deposition date 2014-11-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07938 Fungal_lectin Fungal fucose-specific lectin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.70 Mainly Beta 6 Propeller Neuraminidase Fucose-specific lectin 4d52A00
4C1YA 5H47A 4AH4A 4D52A 5EO8A 4AHAA 1OFZA 5EO7A 4D4UA 4UOUA 1IUCA 4AGTA 4C1YB 4D52B 4D52C 1IUBA 4AGIA 4CSDA
chains in the Genus database with same CATH superfamily
4FPLA 5FZNA 4IN4A 1Z4XA 5D9BA 3ALXA 1RWLA 4GZSA 3JU4A 1MS1A 2VSMA 2GVVA 1N6DA 3FW0A 1W8OA 2QWFA 4CPMA 3B7EA 4FPCA 2VK6A 2IATA 4XJRA 4CSDA 1V0FA 2HTRA 3KGGA 4FPGA 1SO7A 1WCSA 4AGTA 1EUUA 2ZWAA 3V64C 1IVBA 4FZHA 3LI5A 5GX5A 1IJQA 4YZ3A 3WN7A 2GVXA 3S8ZA 1F8EA 2F13A 4MWQA 3U0SA 4AH4A 4HZZA 1NSDA 2QWCA 4WA4A 1PJXA 1WCQA 6NN9A 4IYGA 1NN2A 1KITA 2W20A 2FP9A 7NN9A 1BJIA 1F8BA 1NNAA 3IAXA 1NMAN 4FP2A 2SLIA 1B9SA 5D9CA 4O5TA 4XILA 1F8DA 4XJ9A 1INXA 4MC7A 1QLGA 3WDZA 2DSOA 4GN8A 4QN6A 2BERA 1B9VA 4XJUA 3K37A 3BEQA 4GNCA 2C4LA 4XJZA 4GB1A 4XJQA 1V0EA 1ZI0A 2AGSA 4FPHA 3W09A 1L7FA 1N1TA 3NN9A 5FNRA 3GVKA 1V3BA 2IASA 1Q7FA 1X2JA 2IAOA 2VAQA 2XZJA 1S0JA 3A71A 1F8CA 2OJHA 3AMRA 4R40A 1MZ6A 5GX1A 3UC1A 2YA8A 4YW4A 3SALA 3ZGDA 1MR5A 4MJVA 4NN9A 4CPOA 4ZLRA 2F11A 1INHA 3TI5A 1Z4WA 1N6FA 1U6DX 4YW5A 1ZGKA 1NCDN 4XMAA 3V65B 2VW1A 3WW9A 2AEQA 4XJ8A 4IFNX 2VSKA 3HLHA 4M4NA 1Z4ZA 4D52C 2V91A 4MWUA 4K1IA 1NSBA 2HTVA 4GJTA 4B7RA 2XZIA 4CPYA 3K38A 2A75A 2AH2A 4XHBA 3A9GA 2XCYA 1EUSA 3INBA 4GN9A 3TI8A 3S94A 1CRUA 3I1CA 2IAVA 2IAUA 2B8HA 5H47A 3TIAA 4J9TA 4GEZA 1A4QA 1V3EA 5D9DA 4WA5A 2W5OA 1EUTA 1NMBN 4KS4A 2VK7A 1W21A 4DG6A 1W0OA 1W20A 3VNGA 4D8SA 3BYCA 1MS0A 1CQ1A 4GZTA 4GZWA 4YZ4A 1N7DA 1VCUA 1WP5A 1XOGA 1N1YA 4WEGA 4YW2A 3TI4A 1MS8A 3H6JA 1DILA 4YZ1A 3A9HA 4UF7A 2Z32A 3TC9A 1DIMA 1USRA 4KS2A 2BATA 4IFJA 2F29A 3ZGCA 3H73A 3PJQA 4GZPA 2RKCA 2FHRA 4M3MA 4BBWA 2F26A 3O4PA 4FOVA 1W8NA 2GVUA 2IAWA 4CHBA 4I00A 2HT8A 3LI3A 5EO8A 3HLIA 2VPJA 3A72A 2VK5A 2DG0A 3AMSA 2HU4A 4CPLA 1W0PA 4CPZA 2QWIA 4JMLA 4HZVA 5GX3A 2YDPA 3DR2A 2HTQA 4KS3A 3ADEA 4ASCA 1IVDA 2SIMA 4FPYA 4ZGCA 2QWBA 3K36A 4FOWA 4YW1A 1IUCA 4MWYA 2F28A 4K3YA 1USXA 3S8VA 1V0ZA 1XOEA 4MX0A 4AHAA 4L7BA 1X2RA 1SLLA 3K3AA 2QWHA 5HUKA 3Q6PA 4GDIA 4X49A 3L6VA 4HZXA 4MWRA 4FVKA 1QBIA 2JKBA 4WEFA 1INWA 2HTYA 2HT5A 5F72C 4MWXA 2ZB6A 1C5KA 2ZW9A 2HTUA 3SRGA 1NMCA 4MZAA 4GZQA 1Z50A 2QWEA 4C1YA 2FP8A 1NCAN 3SOQA 1L7GA 1E8TA 3SILA 5M1ZA 1RWIA 2ISMA 3KYAA 3Q6TA 1IVCA 1W1XA 3TIBA 1Z4YA 2FPCA 2F24A 2QWJA 1MZ5A 3D12A 4O5SA 4YZ5A 4XIKA 5B2DA 4B7QA 2XN4A 4X6KA 5CGJA 3G4EA 3P5BL 4K1HA 4FP3A 4D52A 2QE8A 2W8BA 1S0IA 3B69A 3D11A 4MWVA 2IVZA 4QN7A 5GX4A 2X9MA 4MWJA 4XYXA 2VWDA 4L7DA 1A14N 2VVZA 5HUNA 5F9TA 4KS5A 2SILA 1POOA 3CL0A 2IARA 3SLIA 3T1EA 3E5ZA 3S2KA 4B7MA 4WA3A 4FOQA 2IAQA 3O9KA 1C9UA 4GN7A 4X4AA 2DG1A 1EURA 3H72A 4CH9A 1H6LA 4MWWA 1MS4A 2F10A 4GNBA 1V3CA 4FQ4A 4HW6A 4K1JA 4N1BA 3WWAA 4YY8A 2H2NA 3FVZA 5JYYA 4YW3A 2IAXA 4ZY3A 2QWDA 4X47A 4HIZA 1NNBA 1IVEA 5FNTA 3GVJA 1A4GA 3GVLA 3VNHA 1NCCN 2BF6A 1SNTA 1VCJA 1E1AA 2ZB5A 1OFZA 1N1SA 4FPEA 2YA6A 1S1DA 2P4OA 4C1YB 1INVA 5EX7A 2F0ZA 2CMLA 3SREA 4AGIA 1MWEA 2ZZKA 2GVWA 1NPEA 3K39A 3TICA 4HHOA 4M4VA 1IVGA 4NCSA 4HZYA 5NN9A 3TI3A 2FPBA 5GX2A 1MS5A 2F12A 4MZEA 4QNPA 3NSSA 2VW2A 4XJWA 4YZ2A 4H52A 4D52B 2W8BB 4G3NA 4K1KA 2W38A 4JF7A 1E8UA 1INYA 3TI6A 1IVFA 2YDTA 4MJUA 1N6EA 4XOGA 4FPOB 4Q6KA 1V3DA 4QN4A 4FJ6A 4CPNA 3OPZA 1S18A 4L7CA 4XJAA 4IFLX 4SLIA 3O9JA 1V2IA 4XMBA 4XIOA 1NSCA 2W5NA 2BZDA 5HUGA 4XMIA 2G8SA 4MWLA 2QWGA 2HT7A 4QN5A 4M4UA 1MS9A 2YA7A 4FPFA 5HUMA 4QN3A 4NC5A 5FWWA 4GNAA 1INGA 1SUUA 5FNUA 4FPKA 2YA4A 4D4UA 1CVMA 2HTWA 2QWKA 4DGRA 2WOZA 2H2UA 1V04A 3HRPA 3Q6KA 4KS1A 4H53A 2XZKA 3G4HA 3ALWA 4Q1UA 4FOYA 1B9TA 2AEPA 2FLUX 1IUBA 2YA5A 4B7JA 5FNSA 3CKZA 5EO7A 2DYHA 2F27A 4GDJA 3NO0A 4PWZA 4IMBA 4B7NA 4HHQA 3SOVA 3SANA 4HZWA 2F25A 3II7A 2GHSA 1K32A 1E8VA 5FNQA 3V1SA 4IQKA 4XHXA 2HQSA 4GZXA 4UOUA 3CYEA 1NNCA 2QWAA 3CL2A 4XE9A 1SLIA 1Z4VA 1N1VA 5FZJA 1NCBN 5B2CA 1L7HA 2POOA 4FPJA 5GTQA 2VW0A 2C4AA 3SOBB 2HU0A 1MS3A 3DASA 4GZOA 1CRZA 3H71A 5HX0A 4A0PA 3LI4A 2IAPA 1INFA
chains in the Genus database with same CATH topology
4C1YA 5H47A 4AH4A 4D52A 5EO8A 4AHAA 1OFZA 5EO7A 4D4UA 4UOUA 1IUCA 4AGTA 4C1YB 4D52B 4D52C 1IUBA 4AGIA 4CSDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C1Y A;  5H47 A;  4AH4 A;  4D52 A;  5EO8 A;  4AHA A;  1OFZ A;  5EO7 A;  4D4U A;  4UOU A;  1IUC A;  4AGT A;  4C1Y B;  4D52 B;  4D52 C;  1IUB A;  4AGI A;  4CSD A; 
#chains in the Genus database with same CATH topology
 4FPL A;  5FZN A;  4IN4 A;  1Z4X A;  5D9B A;  3ALX A;  1RWL A;  4GZS A;  3JU4 A;  1MS1 A;  2VSM A;  2GVV A;  1N6D A;  3FW0 A;  1W8O A;  2QWF A;  4CPM A;  3B7E A;  4FPC A;  2VK6 A;  2IAT A;  4XJR A;  4CSD A;  1V0F A;  2HTR A;  3KGG A;  4FPG A;  1SO7 A;  1WCS A;  4AGT A;  1EUU A;  2ZWA A;  3V64 C;  1IVB A;  4FZH A;  3LI5 A;  5GX5 A;  1IJQ A;  4YZ3 A;  3WN7 A;  2GVX A;  3S8Z A;  1F8E A;  2F13 A;  4MWQ A;  3U0S A;  4AH4 A;  4HZZ A;  1NSD A;  2QWC A;  4WA4 A;  1PJX A;  1WCQ A;  6NN9 A;  4IYG A;  1NN2 A;  1KIT A;  2W20 A;  2FP9 A;  7NN9 A;  1BJI A;  1F8B A;  1NNA A;  3IAX A;  1NMA N;  4FP2 A;  2SLI A;  1B9S A;  5D9C A;  4O5T A;  4XIL A;  1F8D A;  4XJ9 A;  1INX A;  4MC7 A;  1QLG A;  3WDZ A;  2DSO A;  4GN8 A;  4QN6 A;  2BER A;  1B9V A;  4XJU A;  3K37 A;  3BEQ A;  4GNC A;  2C4L A;  4XJZ A;  4GB1 A;  4XJQ A;  1V0E A;  1ZI0 A;  2AGS A;  4FPH A;  3W09 A;  1L7F A;  1N1T A;  3NN9 A;  5FNR A;  3GVK A;  1V3B A;  2IAS A;  1Q7F A;  1X2J A;  2IAO A;  2VAQ A;  2XZJ A;  1S0J A;  3A71 A;  1F8C A;  2OJH A;  3AMR A;  4R40 A;  1MZ6 A;  5GX1 A;  3UC1 A;  2YA8 A;  4YW4 A;  3SAL A;  3ZGD A;  1MR5 A;  4MJV A;  4NN9 A;  4CPO A;  4ZLR A;  2F11 A;  1INH A;  3TI5 A;  1Z4W A;  1N6F A;  1U6D X;  4YW5 A;  1ZGK A;  1NCD N;  4XMA A;  3V65 B;  2VW1 A;  3WW9 A;  2AEQ A;  4XJ8 A;  4IFN X;  2VSK A;  3HLH A;  4M4N A;  1Z4Z A;  4D52 C;  2V91 A;  4MWU A;  4K1I A;  1NSB A;  2HTV A;  4GJT A;  4B7R A;  2XZI A;  4CPY A;  3K38 A;  2A75 A;  2AH2 A;  4XHB A;  3A9G A;  2XCY A;  1EUS A;  3INB A;  4GN9 A;  3TI8 A;  3S94 A;  1CRU A;  3I1C A;  2IAV A;  2IAU A;  2B8H A;  5H47 A;  3TIA A;  4J9T A;  4GEZ A;  1A4Q A;  1V3E A;  5D9D A;  4WA5 A;  2W5O A;  1EUT A;  1NMB N;  4KS4 A;  2VK7 A;  1W21 A;  4DG6 A;  1W0O A;  1W20 A;  3VNG A;  4D8S A;  3BYC A;  1MS0 A;  1CQ1 A;  4GZT A;  4GZW A;  4YZ4 A;  1N7D A;  1VCU A;  1WP5 A;  1XOG A;  1N1Y A;  4WEG A;  4YW2 A;  3TI4 A;  1MS8 A;  3H6J A;  1DIL A;  4YZ1 A;  3A9H A;  4UF7 A;  2Z32 A;  3TC9 A;  1DIM A;  1USR A;  4KS2 A;  2BAT A;  4IFJ A;  2F29 A;  3ZGC A;  3H73 A;  3PJQ A;  4GZP A;  2RKC A;  2FHR A;  4M3M A;  4BBW A;  2F26 A;  3O4P A;  4FOV A;  1W8N A;  2GVU A;  2IAW A;  4CHB A;  4I00 A;  2HT8 A;  3LI3 A;  5EO8 A;  3HLI A;  2VPJ A;  3A72 A;  2VK5 A;  2DG0 A;  3AMS A;  2HU4 A;  4CPL A;  1W0P A;  4CPZ A;  2QWI A;  4JML A;  4HZV A;  5GX3 A;  2YDP A;  3DR2 A;  2HTQ A;  4KS3 A;  3ADE A;  4ASC A;  1IVD A;  2SIM A;  4FPY A;  4ZGC A;  2QWB A;  3K36 A;  4FOW A;  4YW1 A;  1IUC A;  4MWY A;  2F28 A;  4K3Y A;  1USX A;  3S8V A;  1V0Z A;  1XOE A;  4MX0 A;  4AHA A;  4L7B A;  1X2R A;  1SLL A;  3K3A A;  2QWH A;  5HUK A;  3Q6P A;  4GDI A;  4X49 A;  3L6V A;  4HZX A;  4MWR A;  4FVK A;  1QBI A;  2JKB A;  4WEF A;  1INW A;  2HTY A;  2HT5 A;  5F72 C;  4MWX A;  2ZB6 A;  1C5K A;  2ZW9 A;  2HTU A;  3SRG A;  1NMC A;  4MZA A;  4GZQ A;  1Z50 A;  2QWE A;  4C1Y A;  2FP8 A;  1NCA N;  3SOQ A;  1L7G A;  1E8T A;  3SIL A;  5M1Z A;  1RWI A;  2ISM A;  3KYA A;  3Q6T A;  1IVC A;  1W1X A;  3TIB A;  1Z4Y A;  2FPC A;  2F24 A;  2QWJ A;  1MZ5 A;  3D12 A;  4O5S A;  4YZ5 A;  4XIK A;  5B2D A;  4B7Q A;  2XN4 A;  4X6K A;  5CGJ A;  3G4E A;  3P5B L;  4K1H A;  4FP3 A;  4D52 A;  2QE8 A;  2W8B A;  1S0I A;  3B69 A;  3D11 A;  4MWV A;  2IVZ A;  4QN7 A;  5GX4 A;  2X9M A;  4MWJ A;  4XYX A;  2VWD A;  4L7D A;  1A14 N;  2VVZ A;  5HUN A;  5F9T A;  4KS5 A;  2SIL A;  1POO A;  3CL0 A;  2IAR A;  3SLI A;  3T1E A;  3E5Z A;  3S2K A;  4B7M A;  4WA3 A;  4FOQ A;  2IAQ A;  3O9K A;  1C9U A;  4GN7 A;  4X4A A;  2DG1 A;  1EUR A;  3H72 A;  4CH9 A;  1H6L A;  4MWW A;  1MS4 A;  2F10 A;  4GNB A;  1V3C A;  4FQ4 A;  4HW6 A;  4K1J A;  4N1B A;  3WWA A;  4YY8 A;  2H2N A;  3FVZ A;  5JYY A;  4YW3 A;  2IAX A;  4ZY3 A;  2QWD A;  4X47 A;  4HIZ A;  1NNB A;  1IVE A;  5FNT A;  3GVJ A;  1A4G A;  3GVL A;  3VNH A;  1NCC N;  2BF6 A;  1SNT A;  1VCJ A;  1E1A A;  2ZB5 A;  1OFZ A;  1N1S A;  4FPE A;  2YA6 A;  1S1D A;  2P4O A;  4C1Y B;  1INV A;  5EX7 A;  2F0Z A;  2CML A;  3SRE A;  4AGI A;  1MWE A;  2ZZK A;  2GVW A;  1NPE A;  3K39 A;  3TIC A;  4HHO A;  4M4V A;  1IVG A;  4NCS A;  4HZY A;  5NN9 A;  3TI3 A;  2FPB A;  5GX2 A;  1MS5 A;  2F12 A;  4MZE A;  4QNP A;  3NSS A;  2VW2 A;  4XJW A;  4YZ2 A;  4H52 A;  4D52 B;  2W8B B;  4G3N A;  4K1K A;  2W38 A;  4JF7 A;  1E8U A;  1INY A;  3TI6 A;  1IVF A;  2YDT A;  4MJU A;  1N6E A;  4XOG A;  4FPO B;  4Q6K A;  1V3D A;  4QN4 A;  4FJ6 A;  4CPN A;  3OPZ A;  1S18 A;  4L7C A;  4XJA A;  4IFL X;  4SLI A;  3O9J A;  1V2I A;  4XMB A;  4XIO A;  1NSC A;  2W5N A;  2BZD A;  5HUG A;  4XMI A;  2G8S A;  4MWL A;  2QWG A;  2HT7 A;  4QN5 A;  4M4U A;  1MS9 A;  2YA7 A;  4FPF A;  5HUM A;  4QN3 A;  4NC5 A;  5FWW A;  4GNA A;  1ING A;  1SUU A;  5FNU A;  4FPK A;  2YA4 A;  4D4U A;  1CVM A;  2HTW A;  2QWK A;  4DGR A;  2WOZ A;  2H2U A;  1V04 A;  3HRP A;  3Q6K A;  4KS1 A;  4H53 A;  2XZK A;  3G4H A;  3ALW A;  4Q1U A;  4FOY A;  1B9T A;  2AEP A;  2FLU X;  1IUB A;  2YA5 A;  4B7J A;  5FNS A;  3CKZ A;  5EO7 A;  2DYH A;  2F27 A;  4GDJ A;  3NO0 A;  4PWZ A;  4IMB A;  4B7N A;  4HHQ A;  3SOV A;  3SAN A;  4HZW A;  2F25 A;  3II7 A;  2GHS A;  1K32 A;  1E8V A;  5FNQ A;  3V1S A;  4IQK A;  4XHX A;  2HQS A;  4GZX A;  4UOU A;  3CYE A;  1NNC A;  2QWA A;  3CL2 A;  4XE9 A;  1SLI A;  1Z4V A;  1N1V A;  5FZJ A;  1NCB N;  5B2C A;  1L7H A;  2POO A;  4FPJ A;  5GTQ A;  2VW0 A;  2C4A A;  3SOB B;  2HU0 A;  1MS3 A;  3DAS A;  4GZO A;  1CRZ A;  3H71 A;  5HX0 A;  4A0P A;  3LI4 A;  2IAP A;  1INF A; 
#chains in the Genus database with same CATH homology
 4C1Y A;  5H47 A;  4AH4 A;  4D52 A;  5EO8 A;  4AHA A;  1OFZ A;  5EO7 A;  4D4U A;  4UOU A;  1IUC A;  4AGT A;  4C1Y B;  4D52 B;  4D52 C;  1IUB A;  4AGI A;  4CSD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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