4D86A

Human parp14 (artd8, bal2) - macro domains 1 and 2 in complex with adenosine-5-diphosphate
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
401
structure length
374
Chain Sequence
KCFSRTVLAPGVVLIVQQGDLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFGFPLGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVFGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNLGFPKNIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARRAN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Recognition of Mono-ADP-Ribosylated ARTD10 Substrates by ARTD8 Macrodomains.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Poly [ADP-ribose] polymerase 14
total genus 137
structure length 374
sequence length 401
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4d86A02
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4d86A01
4J4ZA 4J5QA 5DUSA 1VHUA 4IQYA 1LANA 5FSVA 3KR5A 4JLLA 2LGRA 1BPMA 1LAPA 2DX6A 3KQZA 4R7MA 3EJGA 4JGKA 1GYTA 3KR4A 2L8RA 3GPQA 5HIHA 2EWBA 2BFRA 3EJFA 4R76A 2X47A 1LAMA 3KQXA 1BLLE 2EEEA 3IJ3A 3EWPA 3Q6ZA 4R6TA 4ETKA 4TU0A 4ZX8A 1TY8A 3GPOA 3H8FA 3H8GA 4ZY1A 3SIHA 4GUAA 1ZR3A 5FSXA 3KZWA 3SIIA 3SIGA 3GQOA 4KYBA 4J5RA 3GQEA 1SPVA 3V2BA 3IIFA 3EWQA 3V45A 3SIJA 2FXKA 3GPGA 4K3NA 3JZTA 4ABKA 4ETJA 3ETIA 2J9AA 5FSZA 5AILA 5CBMA 3EKEA 2ACFA 1NJRA 2BFQA 1TXZA 5CB3A 4J5SA 5CMSA 4ABLA 4JCAA 2FAVA 4D86A 3H8EA 1LCPA 3PEIA 4ZY0A 1HJZA 3VFQA 1YD9A 4UMLA 2VRIA 4X2TA 3T8WA 4ZI6A 5CB5A 4ESSA 4K0CA 4JVVA 5FSYA 5HOLA 3IIDA 4ZYQA 3EWRA 4GVWA 4GVVA 4ZY2A 5E3BA 2FG1A 4KSIA 2XD7A 1BPNA 2AFCA 1ZR5A 3Q71A 5FSUA 3EW5A 3JRUA 5D8NA 3EWOA 4ZX9A
chains in the Genus database with same CATH superfamily
4J4ZA 4J5QA 5DUSA 1VHUA 4IQYA 1LANA 5FSVA 3KR5A 4JLLA 2LGRA 1BPMA 2JZFA 1LAPA 2DX6A 3KQZA 4R7MA 3EJGA 4JGKA 2KQVA 1GYTA 3KR4A 2L8RA 2W2GA 3GPQA 5HIHA 2EWBA 2BFRA 3EJFA 4R76A 2X47A 1LAMA 3KQXA 1BLLE 2EEEA 3IJ3A 3EWPA 3Q6ZA 4R6TA 4ETKA 4TU0A 4ZX8A 1TY8A 3GPOA 3H8FA 3H8GA 4ZY1A 3SIHA 4GUAA 1ZR3A 5FSXA 3KZWA 3SIIA 3SIGA 3GQOA 4KYBA 2WCTA 4J5RA 3GQEA 1SPVA 2RNKA 3V2BA 3IIFA 3EWQA 3V45A 3SIJA 2FXKA 3GPGA 4K3NA 3JZTA 4ABKA 4ETJA 3ETIA 2J9AA 5FSZA 5AILA 5CBMA 3EKEA 2ACFA 1NJRA 2BFQA 1TXZA 5CB3A 4J5SA 5CMSA 4ABLA 4JCAA 2FAVA 4D86A 3H8EA 3PEIA 1LCPA 2JZDA 4ZY0A 1HJZA 3VFQA 1YD9A 4UMLA 2VRIA 2JZEA 4X2TA 3T8WA 4ZI6A 5CB5A 4ESSA 4K0CA 4JVVA 5FSYA 5HOLA 3IIDA 4ZYQA 3EWRA 4GVWA 4GVVA 4ZY2A 5E3BA 2FG1A 4KSIA 2XD7A 1BPNA 2AFCA 1ZR5A 3Q71A 5FSUA 3EW5A 3JRUA 5D8NA 3EWOA 4ZX9A
chains in the Genus database with same CATH topology
4J4ZA 4J5QA 5DUSA 1VHUA 4IQYA 1LANA 5FSVA 3KR5A 4JLLA 2LGRA 1BPMA 1LAPA 2DX6A 3KQZA 4R7MA 3EJGA 4JGKA 1GYTA 3KR4A 2L8RA 3GPQA 5HIHA 2EWBA 2BFRA 3EJFA 4R76A 2X47A 1LAMA 3KQXA 1BLLE 2EEEA 3IJ3A 3EWPA 3Q6ZA 4R6TA 4ETKA 4TU0A 4ZX8A 1TY8A 3GPOA 3H8FA 3H8GA 4ZY1A 3SIHA 4GUAA 1ZR3A 5FSXA 3KZWA 3SIIA 3SIGA 3GQOA 4KYBA 4J5RA 3GQEA 1SPVA 3V2BA 3IIFA 3EWQA 3V45A 3SIJA 2FXKA 3GPGA 4K3NA 3JZTA 4ABKA 4ETJA 3ETIA 2J9AA 5FSZA 5AILA 5CBMA 3EKEA 2ACFA 1NJRA 2BFQA 1TXZA 5CB3A 4J5SA 5CMSA 4ABLA 4JCAA 2FAVA 4D86A 3H8EA 1LCPA 3PEIA 4ZY0A 1HJZA 3VFQA 1YD9A 4UMLA 2VRIA 4X2TA 3T8WA 4ZI6A 5CB5A 4ESSA 4K0CA 4JVVA 5FSYA 5HOLA 3IIDA 4ZYQA 3EWRA 4GVWA 4GVVA 4ZY2A 5E3BA 2FG1A 4KSIA 2XD7A 1BPNA 2AFCA 1ZR5A 3Q71A 5FSUA 3EW5A 3JRUA 5D8NA 3EWOA 4ZX9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J4Z A;  4J5Q A;  5DUS A;  1VHU A;  4IQY A;  1LAN A;  5FSV A;  3KR5 A;  4JLL A;  2LGR A;  1BPM A;  1LAP A;  2DX6 A;  3KQZ A;  4R7M A;  3EJG A;  4JGK A;  1GYT A;  3KR4 A;  2L8R A;  3GPQ A;  5HIH A;  2EWB A;  2BFR A;  3EJF A;  4R76 A;  2X47 A;  1LAM A;  3KQX A;  1BLL E;  2EEE A;  3IJ3 A;  3EWP A;  3Q6Z A;  4R6T A;  4ETK A;  4TU0 A;  4ZX8 A;  1TY8 A;  3GPO A;  3H8F A;  3H8G A;  4ZY1 A;  3SIH A;  4GUA A;  1ZR3 A;  5FSX A;  3KZW A;  3SII A;  3SIG A;  3GQO A;  4KYB A;  4J5R A;  3GQE A;  1SPV A;  3V2B A;  3IIF A;  3EWQ A;  3V45 A;  3SIJ A;  2FXK A;  3GPG A;  4K3N A;  3JZT A;  4ABK A;  4ETJ A;  3ETI A;  2J9A A;  5FSZ A;  5AIL A;  5CBM A;  3EKE A;  2ACF A;  1NJR A;  2BFQ A;  1TXZ A;  5CB3 A;  4J5S A;  5CMS A;  4ABL A;  4JCA A;  2FAV A;  4D86 A;  3H8E A;  1LCP A;  3PEI A;  4ZY0 A;  1HJZ A;  3VFQ A;  1YD9 A;  4UML A;  2VRI A;  4X2T A;  3T8W A;  4ZI6 A;  5CB5 A;  4ESS A;  4K0C A;  4JVV A;  5FSY A;  5HOL A;  3IID A;  4ZYQ A;  3EWR A;  4GVW A;  4GVV A;  4ZY2 A;  5E3B A;  2FG1 A;  4KSI A;  2XD7 A;  1BPN A;  2AFC A;  1ZR5 A;  3Q71 A;  5FSU A;  3EW5 A;  3JRU A;  5D8N A;  3EWO A;  4ZX9 A; 
#chains in the Genus database with same CATH topology
 4J4Z A;  4J5Q A;  5DUS A;  1VHU A;  4IQY A;  1LAN A;  5FSV A;  3KR5 A;  4JLL A;  2LGR A;  1BPM A;  2JZF A;  1LAP A;  2DX6 A;  3KQZ A;  4R7M A;  3EJG A;  4JGK A;  2KQV A;  1GYT A;  3KR4 A;  2L8R A;  2W2G A;  3GPQ A;  5HIH A;  2EWB A;  2BFR A;  3EJF A;  4R76 A;  2X47 A;  1LAM A;  3KQX A;  1BLL E;  2EEE A;  3IJ3 A;  3EWP A;  3Q6Z A;  4R6T A;  4ETK A;  4TU0 A;  4ZX8 A;  1TY8 A;  3GPO A;  3H8F A;  3H8G A;  4ZY1 A;  3SIH A;  4GUA A;  1ZR3 A;  5FSX A;  3KZW A;  3SII A;  3SIG A;  3GQO A;  4KYB A;  2WCT A;  4J5R A;  3GQE A;  1SPV A;  2RNK A;  3V2B A;  3IIF A;  3EWQ A;  3V45 A;  3SIJ A;  2FXK A;  3GPG A;  4K3N A;  3JZT A;  4ABK A;  4ETJ A;  3ETI A;  2J9A A;  5FSZ A;  5AIL A;  5CBM A;  3EKE A;  2ACF A;  1NJR A;  2BFQ A;  1TXZ A;  5CB3 A;  4J5S A;  5CMS A;  4ABL A;  4JCA A;  2FAV A;  4D86 A;  3H8E A;  3PEI A;  1LCP A;  2JZD A;  4ZY0 A;  1HJZ A;  3VFQ A;  1YD9 A;  4UML A;  2VRI A;  2JZE A;  4X2T A;  3T8W A;  4ZI6 A;  5CB5 A;  4ESS A;  4K0C A;  4JVV A;  5FSY A;  5HOL A;  3IID A;  4ZYQ A;  3EWR A;  4GVW A;  4GVV A;  4ZY2 A;  5E3B A;  2FG1 A;  4KSI A;  2XD7 A;  1BPN A;  2AFC A;  1ZR5 A;  3Q71 A;  5FSU A;  3EW5 A;  3JRU A;  5D8N A;  3EWO A;  4ZX9 A; 
#chains in the Genus database with same CATH homology
 4J4Z A;  4J5Q A;  5DUS A;  1VHU A;  4IQY A;  1LAN A;  5FSV A;  3KR5 A;  4JLL A;  2LGR A;  1BPM A;  1LAP A;  2DX6 A;  3KQZ A;  4R7M A;  3EJG A;  4JGK A;  1GYT A;  3KR4 A;  2L8R A;  3GPQ A;  5HIH A;  2EWB A;  2BFR A;  3EJF A;  4R76 A;  2X47 A;  1LAM A;  3KQX A;  1BLL E;  2EEE A;  3IJ3 A;  3EWP A;  3Q6Z A;  4R6T A;  4ETK A;  4TU0 A;  4ZX8 A;  1TY8 A;  3GPO A;  3H8F A;  3H8G A;  4ZY1 A;  3SIH A;  4GUA A;  1ZR3 A;  5FSX A;  3KZW A;  3SII A;  3SIG A;  3GQO A;  4KYB A;  4J5R A;  3GQE A;  1SPV A;  3V2B A;  3IIF A;  3EWQ A;  3V45 A;  3SIJ A;  2FXK A;  3GPG A;  4K3N A;  3JZT A;  4ABK A;  4ETJ A;  3ETI A;  2J9A A;  5FSZ A;  5AIL A;  5CBM A;  3EKE A;  2ACF A;  1NJR A;  2BFQ A;  1TXZ A;  5CB3 A;  4J5S A;  5CMS A;  4ABL A;  4JCA A;  2FAV A;  4D86 A;  3H8E A;  1LCP A;  3PEI A;  4ZY0 A;  1HJZ A;  3VFQ A;  1YD9 A;  4UML A;  2VRI A;  4X2T A;  3T8W A;  4ZI6 A;  5CB5 A;  4ESS A;  4K0C A;  4JVV A;  5FSY A;  5HOL A;  3IID A;  4ZYQ A;  3EWR A;  4GVW A;  4GVV A;  4ZY2 A;  5E3B A;  2FG1 A;  4KSI A;  2XD7 A;  1BPN A;  2AFC A;  1ZR5 A;  3Q71 A;  5FSU A;  3EW5 A;  3JRU A;  5D8N A;  3EWO A;  4ZX9 A; 
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