The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
119
|
sequence length |
399
|
structure length |
399
|
Chain Sequence |
GAMALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSISLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNRIAREWTQKYAMGGSAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLHKKYSYIRKTRPDGNSFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQGFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDRGEGGTTNPHIFPEGSEPKVYLLYRPGHYDILYK
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
publication title |
OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function.
pubmed doi rcsb |
molecule tags |
Hydrolase/ligase
|
source organism |
Homo sapiens
|
molecule keywords |
Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase O
|
total genus |
119
|
structure length |
399
|
sequence length |
399
|
chains with identical sequence |
B, C
|
ec nomenclature |
ec
2.3.2.23: E2 ubiquitin-conjugating enzyme. |
pdb deposition date | 2012-01-18 |
chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
---|---|---|---|
A | PF00179 | UQ_con | Ubiquitin-conjugating enzyme |
A | PF10275 | Peptidase_C65 | Peptidase C65 Otubain |
cath code
| Class | Architecture | Topology | Homology | Domain |
---|---|---|---|---|---|
Mainly Alpha | Up-down Bundle | 3 helical TM bundles of succinate and fumarate reductases | 3 helical TM bundles of succinate and fumarate reductases | ||
Alpha Beta | Roll | Ubiquitin Conjugating Enzyme | Ubiquitin Conjugating Enzyme | ||
Alpha Beta | 2-Layer Sandwich | Phosphorylase Kinase; domain 1 | Phosphorylase Kinase; domain 1 |