4DDPA

Crystal structure of beclin 1 evolutionarily conserved domain(ecd)
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
200
structure length
195
Chain Sequence
KSVENQMRYAQTQLDKLVFNATFHIWHSGQFGTINNFRLGRLPSVPVEWNEINAAWGQTVLLLHALANKMGLKFQRYRLVPYGNHSYLESLTDKSKELPLYCSGGLRFFWDNKFDHAMVAFLDCVQQFKEEVEKGTRFCLPYRMDVEKGKIEDTGGSGGSYSIKTQFNSEEQWTKALKFMLTNLKWGLAWVSSQF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein
pubmed doi rcsb
molecule tags Membrane protein
source organism Homo sapiens
molecule keywords Beclin-1
total genus 61
structure length 195
sequence length 200
ec nomenclature
pdb deposition date 2012-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF04111 APG6 Apg6 BARA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.40 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Actin-binding Protein, T-fimbrin; domain 1 4ddpA00
4DDPA 3VP7A
chains in the Genus database with same CATH superfamily
1WJOA 5L0OA 1RT8A 5A38A 2IGPA 2WE6A 1WYMA 2D89A 1SH6A 1MB8A 1WYQA 3VP7A 1WIXA 4LVPA 3KMWB 3KMUB 2L3GA 3FERA 2WDTA 2VZCA 2D86A 1UJOA 3HOPA 2VZIB 3CO1A 1PXYA 5FMUA 2HKPA 2VZDA 2VE7C 2R0OA 2JV9A 2QJZA 2K3SA 1EUVA 4EDNA 2E9KA 1WYPA 2EYNA 2QJXA 5FMTA 5J8EA 4LVRA 1VKAA 1WYOA 1WYNA 1H67A 1TJTA 2EE7A 1WYRA 4B7LA 4Q59A 2VZGB 2YRNA 3REPB 5A4BA 1BHDA 4DDPA 5BVRA 2DK9A 4Q57B 1WYLA 2D87A 2R8UA 1P5SA 2WA6A 2D85A 5A36A 4EDLA 2VE7A 2WA5A 4TXKA 3JALM 2EYIA 1DXXA 2RR8A 3F7PA 3HOCA 5A37A 2HL9A 2EQOA 2WA7A 1BKRA 3JARM 2D88A 1V5KA 2K2RA 3KY9A 4EDMA 2WFNA 3I6XA 1AOAA 1PA7A 3JAKM 1AA2A 4Q58A 4TXIA 1UEGA 3EAYA 3HORA 1WKUA 1SH5A 1QAGA 2HL8A 1P2XA
chains in the Genus database with same CATH topology
2HL9A 2VE7A 2EQOA 3EAYA 3VP7A 5FMTA 2IGPA 4LVPA 5FMUA 4DDPA 1EUVA 2HL8A 2HKPA 2WE6A 2WDTA 4LVRA 2VE7C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DDP A;  3VP7 A; 
#chains in the Genus database with same CATH topology
 1WJO A;  5L0O A;  1RT8 A;  5A38 A;  2IGP A;  2WE6 A;  1WYM A;  2D89 A;  1SH6 A;  1MB8 A;  1WYQ A;  3VP7 A;  1WIX A;  4LVP A;  3KMW B;  3KMU B;  2L3G A;  3FER A;  2WDT A;  2VZC A;  2D86 A;  1UJO A;  3HOP A;  2VZI B;  3CO1 A;  1PXY A;  5FMU A;  2HKP A;  2VZD A;  2VE7 C;  2R0O A;  2JV9 A;  2QJZ A;  2K3S A;  1EUV A;  4EDN A;  2E9K A;  1WYP A;  2EYN A;  2QJX A;  5FMT A;  5J8E A;  4LVR A;  1VKA A;  1WYO A;  1WYN A;  1H67 A;  1TJT A;  2EE7 A;  1WYR A;  4B7L A;  4Q59 A;  2VZG B;  2YRN A;  3REP B;  5A4B A;  1BHD A;  4DDP A;  5BVR A;  2DK9 A;  4Q57 B;  1WYL A;  2D87 A;  2R8U A;  1P5S A;  2WA6 A;  2D85 A;  5A36 A;  4EDL A;  2VE7 A;  2WA5 A;  4TXK A;  3JAL M;  2EYI A;  1DXX A;  2RR8 A;  3F7P A;  3HOC A;  5A37 A;  2HL9 A;  2EQO A;  2WA7 A;  1BKR A;  3JAR M;  2D88 A;  1V5K A;  2K2R A;  3KY9 A;  4EDM A;  2WFN A;  3I6X A;  1AOA A;  1PA7 A;  3JAK M;  1AA2 A;  4Q58 A;  4TXI A;  1UEG A;  3EAY A;  3HOR A;  1WKU A;  1SH5 A;  1QAG A;  2HL8 A;  1P2X A; 
#chains in the Genus database with same CATH homology
 2HL9 A;  2VE7 A;  2EQO A;  3EAY A;  3VP7 A;  5FMT A;  2IGP A;  4LVP A;  5FMU A;  4DDP A;  1EUV A;  2HL8 A;  2HKP A;  2WE6 A;  2WDT A;  4LVR A;  2VE7 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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