4DGEC

Trimcyp cyclophilin domain from macaca mulatta: h70c mutant, hiv-1 ca(o-loop) complex
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
143
structure length
136
Chain Sequence
PIVVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRTHPPAMGPLPPGQIREPTGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
pubmed doi rcsb
molecule tags Isomerase/viral protein
source organism Macaca mulatta
molecule keywords TRIMCyp
total genus 47
structure length 136
sequence length 143
chains with identical sequence D
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2012-01-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 4dgeC00
2JPRA 4XFYA 4U0EA 1U7KA 5HGNA 1QRJA 4PH2A 2XDEA 2PWMA 4QNBA 2LF4A 2X83A 1M9DC 4B4NA 4PH0A 4J93A 5HGOA 4XFXA 2M8PA 4LQWC 2XGVA 4PH3A 2GOLB 4XRQA 5HGKA 1L6NA 1M9YC 1M9XC 4U0DA 3MGEA 4XROA 2XGYA 4DGEC 4U0AA 4E92A 2XGUA 1M9EC 3P05A 4XFZA 2PXRC 2WLVA 2M8NA 3BP9A 1AK4C 5HGLA 1M9FC 1P7NA 4E91A 2Y4ZA 3H4EA 2EIAA 2M8LA 5HGMA 1EM9A 2KGFA 1E6JP 4U0BA 2WLVB 4WYMA 4INBA 4DGAC 3H47A 5JPAA 1EIAA 4HTWA 2PWOA 2X82A 4NX4C 3NTEA 1AFVA 2V4XA 2X2DD 2GONA 1GWPA 1D1DA 1G03A 4U0FA 1M9CC 4U0CA
chains in the Genus database with same CATH superfamily
2JPRA 4XFYA 4U0EA 1U7KA 5HGNA 1QRJA 4PH2A 2XDEA 2PWMA 4QNBA 2LF4A 2X83A 1M9DC 4B4NA 4PH0A 4J93A 5HGOA 4XFXA 2M8PA 4LQWC 2XGVA 4PH3A 2GOLB 4XRQA 5HGKA 1L6NA 1M9YC 1M9XC 4U0DA 3MGEA 4XROA 2XGYA 4DGEC 4U0AA 4E92A 2XGUA 1M9EC 3P05A 4XFZA 2PXRC 2WLVA 2M8NA 3BP9A 1AK4C 5HGLA 1M9FC 1P7NA 4E91A 2Y4ZA 3H4EA 2EIAA 2M8LA 5HGMA 1EM9A 2KGFA 1E6JP 4U0BA 2WLVB 4WYMA 4INBA 4DGAC 3H47A 5JPAA 1EIAA 4HTWA 2PWOA 2X82A 4NX4C 3NTEA 1AFVA 2V4XA 2X2DD 2GONA 1GWPA 1D1DA 1G03A 4U0FA 1M9CC 4U0CA
chains in the Genus database with same CATH topology
2JPRA 4XFYA 4U0EA 1U7KA 5HGNA 1QRJA 4PH2A 2XDEA 2PWMA 4QNBA 2LF4A 2X83A 1M9DC 4B4NA 4PH0A 4J93A 5HGOA 4XFXA 2M8PA 4LQWC 2XGVA 4PH3A 2GOLB 4XRQA 5HGKA 1L6NA 1M9YC 1M9XC 4U0DA 3MGEA 4XROA 2XGYA 4DGEC 4U0AA 4E92A 2XGUA 1M9EC 3P05A 4XFZA 2PXRC 2WLVA 2M8NA 3BP9A 1AK4C 5HGLA 1M9FC 1P7NA 4E91A 2Y4ZA 3H4EA 2EIAA 2M8LA 5HGMA 1EM9A 2KGFA 1E6JP 4U0BA 2WLVB 4WYMA 4INBA 4DGAC 3H47A 5JPAA 1EIAA 4HTWA 2PWOA 2X82A 4NX4C 3NTEA 1AFVA 2V4XA 2X2DD 2GONA 1GWPA 1D1DA 1G03A 4U0FA 1M9CC 4U0CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JPR A;  4XFY A;  4U0E A;  1U7K A;  5HGN A;  1QRJ A;  4PH2 A;  2XDE A;  2PWM A;  4QNB A;  2LF4 A;  2X83 A;  1M9D C;  4B4N A;  4PH0 A;  4J93 A;  5HGO A;  4XFX A;  2M8P A;  4LQW C;  2XGV A;  4PH3 A;  2GOL B;  4XRQ A;  5HGK A;  1L6N A;  1M9Y C;  1M9X C;  4U0D A;  3MGE A;  4XRO A;  2XGY A;  4DGE C;  4U0A A;  4E92 A;  2XGU A;  1M9E C;  3P05 A;  4XFZ A;  2PXR C;  2WLV A;  2M8N A;  3BP9 A;  1AK4 C;  5HGL A;  1M9F C;  1P7N A;  4E91 A;  2Y4Z A;  3H4E A;  2EIA A;  2M8L A;  5HGM A;  1EM9 A;  2KGF A;  1E6J P;  4U0B A;  2WLV B;  4WYM A;  4INB A;  4DGA C;  3H47 A;  5JPA A;  1EIA A;  4HTW A;  2PWO A;  2X82 A;  4NX4 C;  3NTE A;  1AFV A;  2V4X A;  2X2D D;  2GON A;  1GWP A;  1D1D A;  1G03 A;  4U0F A;  1M9C C;  4U0C A; 
#chains in the Genus database with same CATH topology
 2JPR A;  4XFY A;  4U0E A;  1U7K A;  5HGN A;  1QRJ A;  4PH2 A;  2XDE A;  2PWM A;  4QNB A;  2LF4 A;  2X83 A;  1M9D C;  4B4N A;  4PH0 A;  4J93 A;  5HGO A;  4XFX A;  2M8P A;  4LQW C;  2XGV A;  4PH3 A;  2GOL B;  4XRQ A;  5HGK A;  1L6N A;  1M9Y C;  1M9X C;  4U0D A;  3MGE A;  4XRO A;  2XGY A;  4DGE C;  4U0A A;  4E92 A;  2XGU A;  1M9E C;  3P05 A;  4XFZ A;  2PXR C;  2WLV A;  2M8N A;  3BP9 A;  1AK4 C;  5HGL A;  1M9F C;  1P7N A;  4E91 A;  2Y4Z A;  3H4E A;  2EIA A;  2M8L A;  5HGM A;  1EM9 A;  2KGF A;  1E6J P;  4U0B A;  2WLV B;  4WYM A;  4INB A;  4DGA C;  3H47 A;  5JPA A;  1EIA A;  4HTW A;  2PWO A;  2X82 A;  4NX4 C;  3NTE A;  1AFV A;  2V4X A;  2X2D D;  2GON A;  1GWP A;  1D1D A;  1G03 A;  4U0F A;  1M9C C;  4U0C A; 
#chains in the Genus database with same CATH homology
 2JPR A;  4XFY A;  4U0E A;  1U7K A;  5HGN A;  1QRJ A;  4PH2 A;  2XDE A;  2PWM A;  4QNB A;  2LF4 A;  2X83 A;  1M9D C;  4B4N A;  4PH0 A;  4J93 A;  5HGO A;  4XFX A;  2M8P A;  4LQW C;  2XGV A;  4PH3 A;  2GOL B;  4XRQ A;  5HGK A;  1L6N A;  1M9Y C;  1M9X C;  4U0D A;  3MGE A;  4XRO A;  2XGY A;  4DGE C;  4U0A A;  4E92 A;  2XGU A;  1M9E C;  3P05 A;  4XFZ A;  2PXR C;  2WLV A;  2M8N A;  3BP9 A;  1AK4 C;  5HGL A;  1M9F C;  1P7N A;  4E91 A;  2Y4Z A;  3H4E A;  2EIA A;  2M8L A;  5HGM A;  1EM9 A;  2KGF A;  1E6J P;  4U0B A;  2WLV B;  4WYM A;  4INB A;  4DGA C;  3H47 A;  5JPA A;  1EIA A;  4HTW A;  2PWO A;  2X82 A;  4NX4 C;  3NTE A;  1AFV A;  2V4X A;  2X2D D;  2GON A;  1GWP A;  1D1D A;  1G03 A;  4U0F A;  1M9C C;  4U0C A; 
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similar chains in the pdb database (?% sequence similarity)

 
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