4DK9A

Crystal structure of mbd4 catalytic domain bound to abasic dna
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
140
structure length
140
Chain Sequence
WTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYPSAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHGIGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNA.
pubmed doi rcsb
molecule keywords 5'-D(*AP*AP*GP*AP*CP*GP*TP*GP*GP*AP*C)-3'
molecule tags Hydrolase/dna
source organism Homo sapiens
total genus 47
structure length 140
sequence length 140
ec nomenclature ec 3.2.2.-:
pdb deposition date 2012-02-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.340.30 Mainly Alpha Orthogonal Bundle Endonuclease III; domain 1 Hypothetical protein; domain 2 4dk9A00
4B21A 5AN4A 1LWVA 1RRQA 3CWTA 1WEGA 1YQRA 5KN9A 1PU6A 1ORNA 1EBMA 1WEIA 1LWWA 4AI4A 2ABKA 3OGDA 1YQMA 4HSBA 1MPGA 2JHNA 4AIAA 1XQPA 1KO9A 1WEFA 2JHJA 1YQKA 4OFAA 4EVVA 4AI5A 3F10A 3FHGA 3I0XA 3D4VA 1KG7A 4EA5A 2NOBA 4EW0A 1NGNA 2OFIA 4B22A 3IH7A 2NOLA 1M3QA 4B24A 2NOIA 2NOEA 1PU8A 3N5NX 4YOQA 1KQJA 4EJYA 4YPRA 2OFKA 1N39A 4YPHA 4OFHA 1NKUA 4E9EA 1P7MA 1KG5A 1MUYA 2I5WA 4E9HA 1P59A 1KG2A 4E9FA 1FN7A 1XQOA 4E9GA 3KNTA 3CVTA 4B23A 2NOFA 1RRSA 3FHFA 1DIZA 3I0WA 1HU0A 2H56A 2YG9A 3KTUA 2NOZA 2YG8A 3CWSA 1ORPA 1YQLA 1LMZA 3CW7A 2NOHA 1KG4A 4UOBA 5CHZA 4EJZA 5KN8A 1N3CA 4EW4A 1KEAA 5DPKA 3CVSA 1MUDA 4DK9A 3F0ZA 1PVSA 4OFEA 1N3AA 3N0UA 1M3HA 2JG6A 1KG6A 4UNFA 4EA4A 2XHIA 1XG7A 4PIIA 3CWUA 3CWAA 1VRLA 1PU7A 1KG3A 3OH9A 3S6IA 3OH6A 3G0QA 3IHOA 1MUNA 1LWYA 3FSPA
chains in the Genus database with same CATH superfamily
4E7IA 4B21A 3OY9A 5AN4A 1LWVA 1U84A 3S3OA 1RRQA 3CWTA 1WEGA 1YQRA 5KN9A 1PU6A 1ORNA 1EBMA 1WEIA 1LWWA 3R2XC 4AI4A 3OYEA 2ABKA 4E7LA 4E7HA 2JPSA 3OGDA 1YQMA 4HSBA 1MPGA 4E7JA 2JHNA 4AIAA 1XQPA 1KO9A 1WEFA 2JHJA 1YQKA 4OFAA 3OYCA 4AI5A 3F10A 4EVVA 3FHGA 3I0XA 3D4VA 1KG7A 3L2WA 4EA5A 2NOBA 4EW0A 1NGNA 3OYHA 4B22A 3IH7A 3OYMA 2OFIA 2NOLA 3OYGA 3L2VA 1M3QA 3LCNA 4B24A 2NOIA 5FROA 2V75A 2NOEA 1PU8A 3N5NX 2W03A 4YOQA 1KQJA 4EJYA 2W04A 4YPRA 2OFKA 1N39A 4YPHA 4OFHA 3OS2A 3OYFA 4BDZA 1NKUA 4E9EA 1P7MA 1KG5A 4BDYA 1MUYA 2I5WA 4E9HA 4BE0A 3OYDA 1P59A 1KG2A 4E9FA 1FN7A 1XQOA 4E9GA 4NZGA 3KNTA 3CVTA 4E7KA 3OYNA 3L2UA 4B23A 3L2RA 4BE2A 3OYLA 2NOFA 1RRSA 3FHFA 1DIZA 3I0WA 1HU0A 3OYIA 5FRNA 2H56A 2YG9A 3OYKA 3KTUA 3OS0A 2NOZA 2YG8A 3CWSA 1ORPA 4IKFA 3S3MA 1YQLA 1LMZA 3CW7A 3OS1A 2NOHA 1KG4A 4UOBA 5CHZA 4EJZA 5KN8A 1N3CA 3S3NA 3OYJA 4EW4A 1KEAA 5DPKA 4BACA 4ZTFA 3CVSA 1MUDA 4DK9A 3F0ZA 3OYBA 4BE1A 1PVSA 3OYAA 4OFEA 1N3AA 3N0UA 1M3HA 2JG6A 3NNQA 4ZTJA 1KG6A 4UNFA 4EA4A 2XHIA 1XG7A 4PIIA 3CWUA 3CWAA 1VRLA 1PU7A 1KG3A 3OH9A 3S6IA 3OH6A 3G0QA 3IHOA 1MUNA 3L2QA 1LWYA 5FRMA 3FSPA 3VW4A
chains in the Genus database with same CATH topology
4B21A 5AN4A 1LWVA 1RRQA 3CWTA 1WEGA 1YQRA 5KN9A 1PU6A 1ORNA 1EBMA 1WEIA 1LWWA 4AI4A 2ABKA 3OGDA 1YQMA 4HSBA 1MPGA 2JHNA 4AIAA 1XQPA 1KO9A 1WEFA 2JHJA 1YQKA 4OFAA 4EVVA 4AI5A 3F10A 3FHGA 3I0XA 3D4VA 1KG7A 4EA5A 2NOBA 4EW0A 1NGNA 2OFIA 4B22A 3IH7A 2NOLA 1M3QA 4B24A 2NOIA 2NOEA 1PU8A 3N5NX 4YOQA 1KQJA 4EJYA 4YPRA 2OFKA 1N39A 4YPHA 4OFHA 1NKUA 4E9EA 1P7MA 1KG5A 1MUYA 2I5WA 4E9HA 1P59A 1KG2A 4E9FA 1FN7A 1XQOA 4E9GA 3KNTA 3CVTA 4B23A 2NOFA 1RRSA 3FHFA 1DIZA 3I0WA 1HU0A 2H56A 2YG9A 3KTUA 2NOZA 2YG8A 3CWSA 1ORPA 1YQLA 1LMZA 3CW7A 2NOHA 1KG4A 4UOBA 5CHZA 4EJZA 5KN8A 1N3CA 4EW4A 1KEAA 5DPKA 3CVSA 1MUDA 4DK9A 3F0ZA 1PVSA 4OFEA 1N3AA 3N0UA 1M3HA 2JG6A 1KG6A 4UNFA 4EA4A 2XHIA 1XG7A 4PIIA 3CWUA 3CWAA 1VRLA 1PU7A 1KG3A 3OH9A 3S6IA 3OH6A 3G0QA 3IHOA 1MUNA 1LWYA 3FSPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4B21 A;  5AN4 A;  1LWV A;  1RRQ A;  3CWT A;  1WEG A;  1YQR A;  5KN9 A;  1PU6 A;  1ORN A;  1EBM A;  1WEI A;  1LWW A;  4AI4 A;  2ABK A;  3OGD A;  1YQM A;  4HSB A;  1MPG A;  2JHN A;  4AIA A;  1XQP A;  1KO9 A;  1WEF A;  2JHJ A;  1YQK A;  4OFA A;  4EVV A;  4AI5 A;  3F10 A;  3FHG A;  3I0X A;  3D4V A;  1KG7 A;  4EA5 A;  2NOB A;  4EW0 A;  1NGN A;  2OFI A;  4B22 A;  3IH7 A;  2NOL A;  1M3Q A;  4B24 A;  2NOI A;  2NOE A;  1PU8 A;  3N5N X;  4YOQ A;  1KQJ A;  4EJY A;  4YPR A;  2OFK A;  1N39 A;  4YPH A;  4OFH A;  1NKU A;  4E9E A;  1P7M A;  1KG5 A;  1MUY A;  2I5W A;  4E9H A;  1P59 A;  1KG2 A;  4E9F A;  1FN7 A;  1XQO A;  4E9G A;  3KNT A;  3CVT A;  4B23 A;  2NOF A;  1RRS A;  3FHF A;  1DIZ A;  3I0W A;  1HU0 A;  2H56 A;  2YG9 A;  3KTU A;  2NOZ A;  2YG8 A;  3CWS A;  1ORP A;  1YQL A;  1LMZ A;  3CW7 A;  2NOH A;  1KG4 A;  4UOB A;  5CHZ A;  4EJZ A;  5KN8 A;  1N3C A;  4EW4 A;  1KEA A;  5DPK A;  3CVS A;  1MUD A;  4DK9 A;  3F0Z A;  1PVS A;  4OFE A;  1N3A A;  3N0U A;  1M3H A;  2JG6 A;  1KG6 A;  4UNF A;  4EA4 A;  2XHI A;  1XG7 A;  4PII A;  3CWU A;  3CWA A;  1VRL A;  1PU7 A;  1KG3 A;  3OH9 A;  3S6I A;  3OH6 A;  3G0Q A;  3IHO A;  1MUN A;  1LWY A;  3FSP A; 
#chains in the Genus database with same CATH topology
 4E7I A;  4B21 A;  3OY9 A;  5AN4 A;  1LWV A;  1U84 A;  3S3O A;  1RRQ A;  3CWT A;  1WEG A;  1YQR A;  5KN9 A;  1PU6 A;  1ORN A;  1EBM A;  1WEI A;  1LWW A;  3R2X C;  4AI4 A;  3OYE A;  2ABK A;  4E7L A;  4E7H A;  2JPS A;  3OGD A;  1YQM A;  4HSB A;  1MPG A;  4E7J A;  2JHN A;  4AIA A;  1XQP A;  1KO9 A;  1WEF A;  2JHJ A;  1YQK A;  4OFA A;  3OYC A;  4AI5 A;  3F10 A;  4EVV A;  3FHG A;  3I0X A;  3D4V A;  1KG7 A;  3L2W A;  4EA5 A;  2NOB A;  4EW0 A;  1NGN A;  3OYH A;  4B22 A;  3IH7 A;  3OYM A;  2OFI A;  2NOL A;  3OYG A;  3L2V A;  1M3Q A;  3LCN A;  4B24 A;  2NOI A;  5FRO A;  2V75 A;  2NOE A;  1PU8 A;  3N5N X;  2W03 A;  4YOQ A;  1KQJ A;  4EJY A;  2W04 A;  4YPR A;  2OFK A;  1N39 A;  4YPH A;  4OFH A;  3OS2 A;  3OYF A;  4BDZ A;  1NKU A;  4E9E A;  1P7M A;  1KG5 A;  4BDY A;  1MUY A;  2I5W A;  4E9H A;  4BE0 A;  3OYD A;  1P59 A;  1KG2 A;  4E9F A;  1FN7 A;  1XQO A;  4E9G A;  4NZG A;  3KNT A;  3CVT A;  4E7K A;  3OYN A;  3L2U A;  4B23 A;  3L2R A;  4BE2 A;  3OYL A;  2NOF A;  1RRS A;  3FHF A;  1DIZ A;  3I0W A;  1HU0 A;  3OYI A;  5FRN A;  2H56 A;  2YG9 A;  3OYK A;  3KTU A;  3OS0 A;  2NOZ A;  2YG8 A;  3CWS A;  1ORP A;  4IKF A;  3S3M A;  1YQL A;  1LMZ A;  3CW7 A;  3OS1 A;  2NOH A;  1KG4 A;  4UOB A;  5CHZ A;  4EJZ A;  5KN8 A;  1N3C A;  3S3N A;  3OYJ A;  4EW4 A;  1KEA A;  5DPK A;  4BAC A;  4ZTF A;  3CVS A;  1MUD A;  4DK9 A;  3F0Z A;  3OYB A;  4BE1 A;  1PVS A;  3OYA A;  4OFE A;  1N3A A;  3N0U A;  1M3H A;  2JG6 A;  3NNQ A;  4ZTJ A;  1KG6 A;  4UNF A;  4EA4 A;  2XHI A;  1XG7 A;  4PII A;  3CWU A;  3CWA A;  1VRL A;  1PU7 A;  1KG3 A;  3OH9 A;  3S6I A;  3OH6 A;  3G0Q A;  3IHO A;  1MUN A;  3L2Q A;  1LWY A;  5FRM A;  3FSP A;  3VW4 A; 
#chains in the Genus database with same CATH homology
 4B21 A;  5AN4 A;  1LWV A;  1RRQ A;  3CWT A;  1WEG A;  1YQR A;  5KN9 A;  1PU6 A;  1ORN A;  1EBM A;  1WEI A;  1LWW A;  4AI4 A;  2ABK A;  3OGD A;  1YQM A;  4HSB A;  1MPG A;  2JHN A;  4AIA A;  1XQP A;  1KO9 A;  1WEF A;  2JHJ A;  1YQK A;  4OFA A;  4EVV A;  4AI5 A;  3F10 A;  3FHG A;  3I0X A;  3D4V A;  1KG7 A;  4EA5 A;  2NOB A;  4EW0 A;  1NGN A;  2OFI A;  4B22 A;  3IH7 A;  2NOL A;  1M3Q A;  4B24 A;  2NOI A;  2NOE A;  1PU8 A;  3N5N X;  4YOQ A;  1KQJ A;  4EJY A;  4YPR A;  2OFK A;  1N39 A;  4YPH A;  4OFH A;  1NKU A;  4E9E A;  1P7M A;  1KG5 A;  1MUY A;  2I5W A;  4E9H A;  1P59 A;  1KG2 A;  4E9F A;  1FN7 A;  1XQO A;  4E9G A;  3KNT A;  3CVT A;  4B23 A;  2NOF A;  1RRS A;  3FHF A;  1DIZ A;  3I0W A;  1HU0 A;  2H56 A;  2YG9 A;  3KTU A;  2NOZ A;  2YG8 A;  3CWS A;  1ORP A;  1YQL A;  1LMZ A;  3CW7 A;  2NOH A;  1KG4 A;  4UOB A;  5CHZ A;  4EJZ A;  5KN8 A;  1N3C A;  4EW4 A;  1KEA A;  5DPK A;  3CVS A;  1MUD A;  4DK9 A;  3F0Z A;  1PVS A;  4OFE A;  1N3A A;  3N0U A;  1M3H A;  2JG6 A;  1KG6 A;  4UNF A;  4EA4 A;  2XHI A;  1XG7 A;  4PII A;  3CWU A;  3CWA A;  1VRL A;  1PU7 A;  1KG3 A;  3OH9 A;  3S6I A;  3OH6 A;  3G0Q A;  3IHO A;  1MUN A;  1LWY A;  3FSP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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