4DNKA

Crystal structure of a tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (ywhab) from homo sapiens at 2.20 a resolution.
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
232
structure length
232
Chain Sequence
TMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide (YWHAQ) from Homo sapiens at 2.20 A resolution
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 protein beta/alpha
total genus 94
structure length 232
sequence length 232
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-02-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 4dnkA00
4IHLA 3M50A 3UALA 1YZ5A 3CU8A 3IQUA 3P1QA 1O9EA 4WRQA 4N7YA 4DHTA 5LHOA 3P1PA 4HKCA 4E2EA 2BR9A 4GNTA 1O9CA 4DHSA 1O9FA 5EWZA 5BTVA 4N7GA 1A38A 5IQPA 1YWTA 3AXYC 4FR3A 4F7RA 2WH0A 2NPMA 4N84A 3M51A 3P1NA 4ZQ0A 2C1NA 3NKXA 3SMMA 5BY9A 4DHUA 2O02A 4Y5IA 3O8IA 3UX0A 3IQVA 3RDHA 3P1OA 4QLIA 3SMNA 4Y32A 3SP5A 3U9XA 1QJAA 2BQ0A 2O8PA 2O98A 4DHOA 4DHRA 5D3EA 5EXAA 5LVZA 1A4OA 3UBWA 4FJ3A 2B05A 4DHNA 4DAUA 2V7DA 4JDDA 3P1RA 4DATA 4JC3A 4DX0A 5LU2A 4Y3BA 4DHPA 5J31A 2C63A 3EFZA 4J6SA 3E6YA 5LX2A 3LW1A 4DHQA 2C74A 2C23A 2BTPA 3SMKA 4ZDRA 4O46A 3T0LA 1IB1A 5LU1A 3MHRA 5HF3A 3UZDA 3SMOA 1A37A 1QJBA 3SMLA 5D2DA 3IQJA 5F74A 3SPRA 4IEAA 4DNKA 5D3FA 4FL5A 4DHMA 4BG6A 2C1JA 3T0MA 3P1SA 1O9DA
chains in the Genus database with same CATH superfamily
4IHLA 3M50A 3UALA 1YZ5A 3CU8A 3IQUA 3P1QA 1O9EA 4QX0A 4WRQA 4N7YA 4DHTA 5LHOA 3P1PA 4QX2A 4HKCA 4E2EA 2BR9A 4GNTA 1O9CA 4DHSA 1O9FA 5EWZA 5BTVA 4N7GA 1A38A 5IQPA 2C9KA 1YWTA 3AXYC 1CIYA 4W8JA 4FR3A 4F7RA 2WH0A 1URJA 2NPMA 4N84A 3M51A 3EB7A 3P1NA 4ZQ0A 2C1NA 3NKXA 3SMMA 5BY9A 4DHUA 2O02A 4Y5IA 1JI6A 3O8IA 3UX0A 3IQVA 4QX1A 3RDHA 3P1OA 1W99A 1S2XA 4QLIA 3SMNA 4Y32A 3SP5A 3X0UA 3U9XA 1QJAA 1I5PA 2BQ0A 2O8PA 2O98A 4DHOA 4DHRA 5D3EA 5EXAA 5LVZA 1A4OA 3UBWA 4FJ3A 2B05A 4DHNA 3I4RA 4DAUA 2V7DA 4JDDA 3P1RA 4ARXA 4DATA 4JC3A 4DX0A 5LU2A 1DLCA 4Y3BA 4DHPA 5J31A 2C63A 3EFZA 4J6SA 3CQGA 4QX3A 3E6YA 5LX2A 3LW1A 4DHQA 2C74A 2C23A 2BTPA 3SMKA 4ZDRA 4O46A 3T0LA 1IB1A 5LU1A 3MHRA 5HF3A 3UZDA 3SMOA 1A37A 1QJBA 3CQCA 3SMLA 3ZHEB 5D2DA 4ARYA 3IQJA 5F74A 3SPRA 4IEAA 4DNKA 4MOAA 4D8MA 5D3FA 4FL5A 4DHMA 4BG6A 2C1JA 3T0MA 3P1SA 1O9DA
chains in the Genus database with same CATH topology
4IHLA 3M50A 3UALA 1YZ5A 3CU8A 3IQUA 3P1QA 1O9EA 4WRQA 4N7YA 4DHTA 5LHOA 3P1PA 4HKCA 4E2EA 2BR9A 4GNTA 1O9CA 4DHSA 1O9FA 5EWZA 5BTVA 4N7GA 1A38A 5IQPA 1YWTA 3AXYC 4FR3A 4F7RA 2WH0A 2NPMA 4N84A 3M51A 3P1NA 4ZQ0A 2C1NA 3NKXA 3SMMA 5BY9A 4DHUA 2O02A 4Y5IA 3O8IA 3UX0A 3IQVA 3RDHA 3P1OA 4QLIA 3SMNA 4Y32A 3SP5A 3U9XA 1QJAA 2BQ0A 2O8PA 2O98A 4DHOA 4DHRA 5D3EA 5EXAA 5LVZA 1A4OA 3UBWA 4FJ3A 2B05A 4DHNA 4DAUA 2V7DA 4JDDA 3P1RA 4DATA 4JC3A 4DX0A 5LU2A 4Y3BA 4DHPA 5J31A 2C63A 3EFZA 4J6SA 3E6YA 5LX2A 3LW1A 4DHQA 2C74A 2C23A 2BTPA 3SMKA 4ZDRA 4O46A 3T0LA 1IB1A 5LU1A 3MHRA 5HF3A 3UZDA 3SMOA 1A37A 1QJBA 3SMLA 5D2DA 3IQJA 5F74A 3SPRA 4IEAA 4DNKA 5D3FA 4FL5A 4DHMA 4BG6A 2C1JA 3T0MA 3P1SA 1O9DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IHL A;  3M50 A;  3UAL A;  1YZ5 A;  3CU8 A;  3IQU A;  3P1Q A;  1O9E A;  4WRQ A;  4N7Y A;  4DHT A;  5LHO A;  3P1P A;  4HKC A;  4E2E A;  2BR9 A;  4GNT A;  1O9C A;  4DHS A;  1O9F A;  5EWZ A;  5BTV A;  4N7G A;  1A38 A;  5IQP A;  1YWT A;  3AXY C;  4FR3 A;  4F7R A;  2WH0 A;  2NPM A;  4N84 A;  3M51 A;  3P1N A;  4ZQ0 A;  2C1N A;  3NKX A;  3SMM A;  5BY9 A;  4DHU A;  2O02 A;  4Y5I A;  3O8I A;  3UX0 A;  3IQV A;  3RDH A;  3P1O A;  4QLI A;  3SMN A;  4Y32 A;  3SP5 A;  3U9X A;  1QJA A;  2BQ0 A;  2O8P A;  2O98 A;  4DHO A;  4DHR A;  5D3E A;  5EXA A;  5LVZ A;  1A4O A;  3UBW A;  4FJ3 A;  2B05 A;  4DHN A;  4DAU A;  2V7D A;  4JDD A;  3P1R A;  4DAT A;  4JC3 A;  4DX0 A;  5LU2 A;  4Y3B A;  4DHP A;  5J31 A;  2C63 A;  3EFZ A;  4J6S A;  3E6Y A;  5LX2 A;  3LW1 A;  4DHQ A;  2C74 A;  2C23 A;  2BTP A;  3SMK A;  4ZDR A;  4O46 A;  3T0L A;  1IB1 A;  5LU1 A;  3MHR A;  5HF3 A;  3UZD A;  3SMO A;  1A37 A;  1QJB A;  3SML A;  5D2D A;  3IQJ A;  5F74 A;  3SPR A;  4IEA A;  4DNK A;  5D3F A;  4FL5 A;  4DHM A;  4BG6 A;  2C1J A;  3T0M A;  3P1S A;  1O9D A; 
#chains in the Genus database with same CATH topology
 4IHL A;  3M50 A;  3UAL A;  1YZ5 A;  3CU8 A;  3IQU A;  3P1Q A;  1O9E A;  4QX0 A;  4WRQ A;  4N7Y A;  4DHT A;  5LHO A;  3P1P A;  4QX2 A;  4HKC A;  4E2E A;  2BR9 A;  4GNT A;  1O9C A;  4DHS A;  1O9F A;  5EWZ A;  5BTV A;  4N7G A;  1A38 A;  5IQP A;  2C9K A;  1YWT A;  3AXY C;  1CIY A;  4W8J A;  4FR3 A;  4F7R A;  2WH0 A;  1URJ A;  2NPM A;  4N84 A;  3M51 A;  3EB7 A;  3P1N A;  4ZQ0 A;  2C1N A;  3NKX A;  3SMM A;  5BY9 A;  4DHU A;  2O02 A;  4Y5I A;  1JI6 A;  3O8I A;  3UX0 A;  3IQV A;  4QX1 A;  3RDH A;  3P1O A;  1W99 A;  1S2X A;  4QLI A;  3SMN A;  4Y32 A;  3SP5 A;  3X0U A;  3U9X A;  1QJA A;  1I5P A;  2BQ0 A;  2O8P A;  2O98 A;  4DHO A;  4DHR A;  5D3E A;  5EXA A;  5LVZ A;  1A4O A;  3UBW A;  4FJ3 A;  2B05 A;  4DHN A;  3I4R A;  4DAU A;  2V7D A;  4JDD A;  3P1R A;  4ARX A;  4DAT A;  4JC3 A;  4DX0 A;  5LU2 A;  1DLC A;  4Y3B A;  4DHP A;  5J31 A;  2C63 A;  3EFZ A;  4J6S A;  3CQG A;  4QX3 A;  3E6Y A;  5LX2 A;  3LW1 A;  4DHQ A;  2C74 A;  2C23 A;  2BTP A;  3SMK A;  4ZDR A;  4O46 A;  3T0L A;  1IB1 A;  5LU1 A;  3MHR A;  5HF3 A;  3UZD A;  3SMO A;  1A37 A;  1QJB A;  3CQC A;  3SML A;  3ZHE B;  5D2D A;  4ARY A;  3IQJ A;  5F74 A;  3SPR A;  4IEA A;  4DNK A;  4MOA A;  4D8M A;  5D3F A;  4FL5 A;  4DHM A;  4BG6 A;  2C1J A;  3T0M A;  3P1S A;  1O9D A; 
#chains in the Genus database with same CATH homology
 4IHL A;  3M50 A;  3UAL A;  1YZ5 A;  3CU8 A;  3IQU A;  3P1Q A;  1O9E A;  4WRQ A;  4N7Y A;  4DHT A;  5LHO A;  3P1P A;  4HKC A;  4E2E A;  2BR9 A;  4GNT A;  1O9C A;  4DHS A;  1O9F A;  5EWZ A;  5BTV A;  4N7G A;  1A38 A;  5IQP A;  1YWT A;  3AXY C;  4FR3 A;  4F7R A;  2WH0 A;  2NPM A;  4N84 A;  3M51 A;  3P1N A;  4ZQ0 A;  2C1N A;  3NKX A;  3SMM A;  5BY9 A;  4DHU A;  2O02 A;  4Y5I A;  3O8I A;  3UX0 A;  3IQV A;  3RDH A;  3P1O A;  4QLI A;  3SMN A;  4Y32 A;  3SP5 A;  3U9X A;  1QJA A;  2BQ0 A;  2O8P A;  2O98 A;  4DHO A;  4DHR A;  5D3E A;  5EXA A;  5LVZ A;  1A4O A;  3UBW A;  4FJ3 A;  2B05 A;  4DHN A;  4DAU A;  2V7D A;  4JDD A;  3P1R A;  4DAT A;  4JC3 A;  4DX0 A;  5LU2 A;  4Y3B A;  4DHP A;  5J31 A;  2C63 A;  3EFZ A;  4J6S A;  3E6Y A;  5LX2 A;  3LW1 A;  4DHQ A;  2C74 A;  2C23 A;  2BTP A;  3SMK A;  4ZDR A;  4O46 A;  3T0L A;  1IB1 A;  5LU1 A;  3MHR A;  5HF3 A;  3UZD A;  3SMO A;  1A37 A;  1QJB A;  3SML A;  5D2D A;  3IQJ A;  5F74 A;  3SPR A;  4IEA A;  4DNK A;  5D3F A;  4FL5 A;  4DHM A;  4BG6 A;  2C1J A;  3T0M A;  3P1S A;  1O9D A; 
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