4DRKA

Evaluation of synthetic fk506 analogs as ligands for fkbp51 and fkbp52: complex of fkbp51 with {3-[(1r)-3-(3,4-dimethoxyphenyl)-1-({[(2s)-1-(3,3-dimethyl-2-oxopentanoyl)piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
128
structure length
128
Chain Sequence
GAPATVTEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52.
pubmed doi rcsb
molecule tags Isomerase
source organism Homo sapiens
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP5
total genus 34
structure length 128
sequence length 128
chains with identical sequence B
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2012-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00254 FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 4drkA00
2F4EA 1FKGA 3RGCA 1JNTA 1J4HA 4FN2A 4ODOA 4R0XA 1B6CA 3O5IA 4MGVA 3TCZA 1P5QA 3ODKA 1QPLA 5HUAA 2XP8A 2RUCA 4DRJA 3H9RB 1D6OA 3O5OA 4LAVA 5GPGA 3O5KA 3KABA 2FAPA 5HW6A 2LKNA 1PBKA 2Q5AA 3WH0A 1F40A 2KGJA 2MLXA 2IF4A 2D9FA 2MLYA 2KO7A 2XP3A 4ODQA 1FKFA 3IK8A 2OFNA 3KCEA 4FAPA 2RURA 2KI3A 1C9HA 1T11A 2ZR6A 3NRKA 4DRPA 2RUQA 3IKDA 2DG9A 2PBCA 4GIVA 4QT3A 4TX0A 4LAWA 4BF8A 5HWCA 3UQBA 3O5PA 3PRDA 4NNRA 3KAFA 4MSPA 2JZVA 4G50A 5DITA 2KR7A 3TDBA 4JFMA 1FKSA 3KAHA 3UQAA 4ODKA 3JYJA 3UI6A 5DIUA 3O5JA 1FKHA 1ROUA 5B8IC 4DRIA 4ODNA 2K8IA 4DZ2A 1A7XA 2FKEA 4QIBA 1FKTA 2M1IA 5D75A 1L1PA 3B7XA 4IQ2A 2PV3A 3O5DA 1YATA 4TYOA 1U79A 5HTGA 5DIVA 1NSGA 2KE0A 3KAGA 4J4NA 4LAXA 4ODPA 2MLZA 4JFIA 3NI6A 1N1AA 3VAWA 4JYSA 5I98A 4DROA 1M5YA 4TW8A 4DIPA 3CGMA 1FJDA 2DG3A 2MNTA 2PPOA 1D7IA 3KADA 5HT1A 1JNSA 4U85A 1FD9A 1Y0OA 4JFLA 2XP9A 4ITZA 2PPPA 1BKFA 3MDYB 3O5MA 2XP6A 1J4RA 3O5QA 4IQCA 4DRKA 1J6YA 1QPFA 3TC5A 4JFKA 5BXJA 1KT0A 3KACA 1F8AB 2N87A 1Q6UA 3UQIA 3IHZA 4ODMA 2ITKA 4C02B 5J6EA 2XPAA 1FKRA 4ODLA 2F2DA 2KFWA 2AWGA 4W9QA 1R9HA 3OOBA 2VN1A 3PRBA 2ZQUA 3JYMA 3O5LA 4W9OA 3GPKA 3PA7A 3O5EA 4U84A 2XP5A 3KZ7A 1J4IA 1NMVA 2ZQVA 4O2TA 3O5RA 4QT2A 2MPHA 2PV1A 4GGQA 5HKGA 4N19A 3KAIA 2PV2A 2ZQTA 1Q6IA 1D7JA 2LJ4A 2PPNA 1EQ3A 3O5FA 4TNSA 4DZ3A 2DG4A 4TW6A 1TCOC 1NMWA 4DRQA 3O5GA 2M2AA 1FKBA 1YW5A 4DT4A 1HXVA 4DH0A 2LGOA 4DRNA 2VCDA 4DRMA 2Y78A 2M08A 2RQSA 3UF8A 3LUOA 2ZQSA 2MF9A 2ZR4A 3EY6A 3UI4A 3UI5A 4J4OA 3IKGA 1ZCNA 1D7HA 1ZK6A 2XP7A 4DRHA 5HW7A 2RUDA 1EYMA 1FKKA 4JFJA 3JXVA 2F21A 2L2SA 4W9PA 1FKJA 1QZ2A 1W26A 4IPXA 2ZR5A 3NTPA 1ROTA 1FAPA 1Q6HA 1PINA 1FKDA 1FKIA 3CGNA 4U86A 3RFWA 1JVWA 2RSEA 2XPBA 4ODRA 2LPVA 1Q1CA 2UZ5A 4TW7A 1FKLA 1BL4A 4G2PA 3FAPA 2XP4A 5HW8A 3I6CA 5HWBA 1KT1A 4LAYA
chains in the Genus database with same CATH superfamily
2F4EA 2QF8A 5HBFA 1HKMA 1JNTA 4ODOA 2AOSA 5DO2A 2P4VA 3TCZA 1LJYA 4WKHA 1QPLA 2RUCA 4LAVA 1H0GA 4ZS6A 4R5EA 3WH0A 4MPKA 2MLXA 2YBUA 2XP3A 1CTNA 1FKFA 3IK8A 1NWSA 2OFNA 3KCEA 2RURA 3ARUA 1C9HA 1JNDA 4TX0A 4LAWA 3O5PA 3PRDA 3BMBA 2KR7A 1LG2A 1XHGA 3KAHA 4ODKA 3UI6A 1NH6A 1LG1A 1FKTA 1ZBKA 2M1IA 1L1PA 3ARPA 4P8UA 4J4NA 4HBEA 4JFIA 4MNKA 3G6LA 1OGBA 3FXYA 3BXWA 4DIPA 3CGMA 1LQ0A 2DG3A 4L3NA 1W1TA 2IUZA 1Y0OA 4JFLA 3CHEA 4ITZA 2PPPA 3O5QA 2XP6A 3GU0A 4DRKA 1K9TA 1KT0A 1E6PA 3KACA 4WKAA 1WB0A 4C02B 5J6EA 2ITKA 1FKRA 2F2DA 1E15A 2AWGA 3AS3A 2O92A 3PRBA 4HARA 2DSWA 4S3JA 1NMVA 2ZQVA 1HKJA 4Q7NA 1EDQA 1NWRA 1NMWA 4P8VA 2M2AA 1HXVA 1YW5A 4DT4A 1RD6A 2Y78A 2M08A 2YBTA 2ZQSA 2MF9A 1JNEA 2B5UB 4J4OA 3ARRA 1ZCNA 1D7HA 3WD0A 2XP7A 2B31A 4WIWA 1W26A 1W9VA 2ZR5A 1H0IA 1E6ZA 3AS2A 3CHFA 1LL6A 1JVWA 1LL4A 2XPBA 2UZ5A 1IX5A 2XP4A 4AY1A 4LAYA 4LGXA 4Z2HA 1J4HA 2A3EA 1E44A 1B6CA 3O5IA 1P5QA 3ODKA 3WD2A 2XP8A 3H9RB 3B9AA 3O5KA 3KABA 5HW6A 2LKNA 3CHCA 2IF4A 2WLYA 2G41A 2MLYA 4Z2JA 3W4RA 1EIBA 1WNOA 3WL1A 2ZR6A 3WD1A 2RUQA 3UQBA 3AROA 3ARVA 4BF8A 1W1YA 3WKZA 3KAFA 4G50A 1ZL1A 1FKSA 3ALGA 3UQAA 3JYJA 5DIUA 1ROUA 4DRIA 2K8IA 1A7XA 1W9PA 4IQ2A 3B9DA 1YATA 1NWTA 4TYOA 5GPRA 2KE0A 4ODPA 1N1AA 4JYSA 2PN0A 5I98A 4DROA 1FJDA 1X6NA 2MNTA 1JNSA 2XP9A 3O5MA 3B8SA 4IQCA 1QPFA 4JFKA 1F8AB 3IHZA 2KFWA 3EIPA 3GTYX 3JYMA 4KR0B 3GPKA 4U84A 1J4IA 4QT2A 2MPHA 4WKFA 3WL0A 1EQ3A 2DT3A 3O5FA 4TW6A 1TCOC 1ZB5A 2DT2A 2VCDA 3ARXA 3CZ8A 3LUOA 2ZR4A 3EY6A 3RM8A 3UI5A 3IKGA 1ZK6A 5JH8A 1ITXA 4DRHA 3WQVA 1EYMA 1FKKA 1W1VA 2L2SA 2EULA 4UDMA 4IT6A 4P8WA 1O6IA 1Q6HA 1FKIA 2RSEA 4ODRA 4TW7A 2LPVA 1GRJA 5HWBA 3QOKA 1FKGA 4FN2A 2A3CA 4PTMA 4DWSD 3ARZA 5HUAA 4MNMA 3O5OA 5GPGA 3RMEA 2FAPA 1F40A 2KGJA 2D9FA 2KO7A 1SR0A 3ARTA 4ODQA 4DWSC 4FAPA 3PRAA 2KI3A 4DRPA 3ARQA 2PBCA 4GIVA 4QT3A 3WD4A 5DF0A 1EHNA 4NNRA 2JZVA 3TDBA 4ZPTR 3O5JA 1FKHA 5B8IC 2WLZA 2ETNA 4MAVA 4DWSB 4ODNA 1VF8A 5GQBA 4QIBA 1TFVA 4QZVB 1UR9A 3O5DA 5HTGA 1NSGA 3KAGA 1ZU8A 3ARSA 4TW8A 1XRVA 2PPOA 1WAWA 4HBOA 1FD9A 5DEZA 1HKIA 1ZBWA 1J6YA 3TC5A 1GOIA 1Q6UA 4W9QA 3OOBA 2VN1A 2ZQUA 3O5LA 2OLHA 4W9OA 4O2TA 3O5RA 1HJVA 2PV1A 2PV2A 2ZQTA 2LJ4A 1ZBVA 4TNSA 2O9OA 4DRQA 2F23A 4DH0A 2LGOA 3WIJA 2DSUA 2RQSA 3UF8A 3UI4A 1HKKA 3AS1A 4JFJA 1SYTA 2F21A 3JXVA 4W9PA 4Z2KA 4MTVA 3NTPA 3RM4A 1FAPA 4URIA 1PINA 1FKDA 3CGNA 3RFWA 1Q1CA 1FKLA 1BL4A 5HW8A 4ODMA 1E9LA 3CHDA 3AS0A 4WJXA 3ARYA 3RGCA 4R0XA 3ALFA 3OA5A 4MGVA 4P8XA 2A3BA 4S3KA 4DRJA 1D6OA 2A3AA 1PBKA 2Q5AA 2DSVA 4IT4A 1GUVA 2G8ZA 3B9EA 1KFWA 1T11A 3NRKA 3IKDA 2DG9A 3RM9A 5HWCA 5DITA 4MSPA 4ZPVR 4JFMA 4DWSA 3FY1A 1NWUA 4XAKA 3WD3A 4DZ2A 2FKEA 5D75A 1HJWA 3B7XA 2PV3A 1U79A 1OGGA 5DIVA 4LAXA 2MLZA 3NI6A 3VAWA 2WM0A 1W9UA 1M5YA 4KQZA 4ZPWR 1D7IA 3KADA 5HT1A 1D2KA 4U85A 2DT1A 2DPEA 1BKFA 3MDYB 1J4RA 4Z2GA 1LL7A 5BXJA 2N87A 4MNLA 3UQIA 1HJXA 2XPAA 3CH9A 4L72B 4ODLA 4ML4A 2WK2A 3WQWA 1R9HA 1ZBCA 4NSBA 1E6NA 3PA7A 3O5EA 4WK9A 2XP5A 3KZ7A 4W5UA 5HKGA 4GGQA 4N19A 3KAIA 4Q22A 4MNJA 1GPFA 3PR9A 2PI6A 1OWQA 1Q6IA 1D7JA 2PPNA 4DZ3A 2DG4A 3O5GA 1FKBA 3AQUA 1E6RA 4DRNA 4DRMA 4NZCA 4Z2LA 3G6MA 3ARWA 1W1PA 2DT0A 2FDMA 5HW7A 2RUDA 1FFQA 2ESCA 1FKJA 1QZ2A 4IPXA 4Z2IA 1ROTA 1JCHB 1FFRA 4U86A 1X6LA 4G2PA 3FAPA 3I6CA 2DSZA 1KT1A 1UR8A
chains in the Genus database with same CATH topology
2F4EA 2QF8A 5HBFA 1HKMA 1JNTA 4ODOA 2AOSA 5DO2A 3TCZA 1LJYA 4WKHA 1QPLA 2RUCA 4LAVA 1H0GA 4ZS6A 4R5EA 3WH0A 4MPKA 2MLXA 2YBUA 2XP3A 1CTNA 1FKFA 3IK8A 1NWSA 2OFNA 3KCEA 2RURA 3ARUA 1C9HA 1JNDA 4TX0A 4LAWA 3O5PA 3PRDA 2KR7A 1LG2A 1XHGA 3KAHA 4ODKA 3UI6A 1NH6A 1LG1A 1FKTA 1ZBKA 2M1IA 1L1PA 3ARPA 4P8UA 4J4NA 4HBEA 4JFIA 4MNKA 3G6LA 1OGBA 3FXYA 3BXWA 4DIPA 3CGMA 1LQ0A 2DG3A 4L3NA 1W1TA 2IUZA 1Y0OA 4JFLA 3CHEA 4ITZA 2PPPA 3O5QA 2XP6A 4DRKA 1K9TA 1KT0A 1E6PA 3KACA 4WKAA 1WB0A 4C02B 5J6EA 2ITKA 1FKRA 2F2DA 1E15A 2AWGA 3AS3A 2O92A 3PRBA 4HARA 2DSWA 4S3JA 1NMVA 2ZQVA 1HKJA 4Q7NA 1EDQA 1NWRA 1NMWA 4P8VA 2M2AA 1HXVA 1YW5A 4DT4A 1RD6A 2Y78A 2M08A 2YBTA 2ZQSA 2MF9A 1JNEA 4J4OA 3ARRA 1ZCNA 1D7HA 3WD0A 2XP7A 2B31A 4WIWA 1W26A 1W9VA 2ZR5A 1H0IA 1E6ZA 3AS2A 3CHFA 1LL6A 1JVWA 1LL4A 2XPBA 2UZ5A 1IX5A 2XP4A 4AY1A 4LAYA 4LGXA 4Z2HA 1J4HA 2A3EA 1B6CA 3O5IA 1P5QA 3ODKA 3WD2A 2XP8A 3H9RB 3B9AA 3O5KA 3KABA 5HW6A 2LKNA 3CHCA 2IF4A 2WLYA 2G41A 2MLYA 4Z2JA 3W4RA 1EIBA 1WNOA 3WL1A 2ZR6A 3WD1A 2RUQA 3UQBA 3AROA 3ARVA 4BF8A 1W1YA 3WKZA 3KAFA 4G50A 1ZL1A 1FKSA 3ALGA 3UQAA 3JYJA 5DIUA 1ROUA 4DRIA 2K8IA 1A7XA 1W9PA 4IQ2A 3B9DA 1YATA 1NWTA 4TYOA 5GPRA 2KE0A 4ODPA 1N1AA 4JYSA 5I98A 4DROA 1FJDA 1X6NA 2MNTA 1JNSA 2XP9A 3O5MA 3B8SA 4IQCA 1QPFA 4JFKA 1F8AB 3IHZA 2KFWA 3JYMA 4KR0B 3GPKA 4U84A 1J4IA 4QT2A 2MPHA 4WKFA 3WL0A 1EQ3A 2DT3A 3O5FA 4TW6A 1TCOC 1ZB5A 2DT2A 2VCDA 3ARXA 3CZ8A 3LUOA 2ZR4A 3EY6A 3RM8A 3UI5A 3IKGA 1ZK6A 5JH8A 1ITXA 4DRHA 3WQVA 1EYMA 1FKKA 1W1VA 2L2SA 4IT6A 4P8WA 1O6IA 1Q6HA 1FKIA 2RSEA 4ODRA 4TW7A 2LPVA 5HWBA 3QOKA 1FKGA 4FN2A 2A3CA 4PTMA 4DWSD 3ARZA 5HUAA 4MNMA 3O5OA 5GPGA 3RMEA 2FAPA 1F40A 2KGJA 2D9FA 2KO7A 1SR0A 3ARTA 4ODQA 4DWSC 4FAPA 3PRAA 2KI3A 4DRPA 3ARQA 2PBCA 4GIVA 4QT3A 3WD4A 5DF0A 1EHNA 4NNRA 2JZVA 3TDBA 4ZPTR 3O5JA 1FKHA 5B8IC 2WLZA 4MAVA 4DWSB 4ODNA 1VF8A 5GQBA 4QIBA 1TFVA 4QZVB 1UR9A 3O5DA 5HTGA 1NSGA 3KAGA 1ZU8A 3ARSA 4TW8A 1XRVA 2PPOA 1WAWA 4HBOA 1FD9A 5DEZA 1HKIA 1ZBWA 1J6YA 3TC5A 1GOIA 1Q6UA 4W9QA 3OOBA 2VN1A 2ZQUA 3O5LA 2OLHA 4W9OA 4O2TA 3O5RA 1HJVA 2PV1A 2PV2A 2ZQTA 2LJ4A 1ZBVA 4TNSA 2O9OA 4DRQA 4DH0A 2LGOA 3WIJA 2DSUA 2RQSA 3UF8A 3UI4A 1HKKA 3AS1A 4JFJA 1SYTA 2F21A 3JXVA 4W9PA 4Z2KA 4MTVA 3NTPA 3RM4A 1FAPA 4URIA 1PINA 1FKDA 3CGNA 3RFWA 1Q1CA 1FKLA 1BL4A 5HW8A 4ODMA 1E9LA 3CHDA 3AS0A 4WJXA 3ARYA 3RGCA 4R0XA 3ALFA 3OA5A 4MGVA 4P8XA 2A3BA 4S3KA 4DRJA 1D6OA 2A3AA 1PBKA 2Q5AA 2DSVA 4IT4A 1GUVA 2G8ZA 3B9EA 1KFWA 1T11A 3NRKA 3IKDA 2DG9A 3RM9A 5HWCA 5DITA 4MSPA 4ZPVR 4JFMA 4DWSA 3FY1A 1NWUA 4XAKA 3WD3A 4DZ2A 2FKEA 5D75A 1HJWA 3B7XA 2PV3A 1U79A 1OGGA 5DIVA 4LAXA 2MLZA 3NI6A 3VAWA 2WM0A 1W9UA 1M5YA 4KQZA 4ZPWR 1D7IA 3KADA 5HT1A 1D2KA 4U85A 2DT1A 2DPEA 1BKFA 3MDYB 1J4RA 4Z2GA 1LL7A 5BXJA 2N87A 4MNLA 3UQIA 1HJXA 2XPAA 3CH9A 4L72B 4ODLA 4ML4A 2WK2A 3WQWA 1R9HA 1ZBCA 4NSBA 1E6NA 3PA7A 3O5EA 4WK9A 2XP5A 3KZ7A 4W5UA 5HKGA 4GGQA 4N19A 3KAIA 4Q22A 4MNJA 1GPFA 3PR9A 2PI6A 1OWQA 1Q6IA 1D7JA 2PPNA 4DZ3A 2DG4A 3O5GA 1FKBA 3AQUA 1E6RA 4DRNA 4DRMA 4NZCA 4Z2LA 3G6MA 3ARWA 1W1PA 2DT0A 2FDMA 5HW7A 2RUDA 1FFQA 2ESCA 1FKJA 1QZ2A 4IPXA 4Z2IA 1ROTA 1FFRA 4U86A 1X6LA 4G2PA 3FAPA 3I6CA 2DSZA 1KT1A 1UR8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F4E A;  1FKG A;  3RGC A;  1JNT A;  1J4H A;  4FN2 A;  4ODO A;  4R0X A;  1B6C A;  3O5I A;  4MGV A;  3TCZ A;  1P5Q A;  3ODK A;  1QPL A;  5HUA A;  2XP8 A;  2RUC A;  4DRJ A;  3H9R B;  1D6O A;  3O5O A;  4LAV A;  5GPG A;  3O5K A;  3KAB A;  2FAP A;  5HW6 A;  2LKN A;  1PBK A;  2Q5A A;  3WH0 A;  1F40 A;  2KGJ A;  2MLX A;  2IF4 A;  2D9F A;  2MLY A;  2KO7 A;  2XP3 A;  4ODQ A;  1FKF A;  3IK8 A;  2OFN A;  3KCE A;  4FAP A;  2RUR A;  2KI3 A;  1C9H A;  1T11 A;  2ZR6 A;  3NRK A;  4DRP A;  2RUQ A;  3IKD A;  2DG9 A;  2PBC A;  4GIV A;  4QT3 A;  4TX0 A;  4LAW A;  4BF8 A;  5HWC A;  3UQB A;  3O5P A;  3PRD A;  4NNR A;  3KAF A;  4MSP A;  2JZV A;  4G50 A;  5DIT A;  2KR7 A;  3TDB A;  4JFM A;  1FKS A;  3KAH A;  3UQA A;  4ODK A;  3JYJ A;  3UI6 A;  5DIU A;  3O5J A;  1FKH A;  1ROU A;  5B8I C;  4DRI A;  4ODN A;  2K8I A;  4DZ2 A;  1A7X A;  2FKE A;  4QIB A;  1FKT A;  2M1I A;  5D75 A;  1L1P A;  3B7X A;  4IQ2 A;  2PV3 A;  3O5D A;  1YAT A;  4TYO A;  1U79 A;  5HTG A;  5DIV A;  1NSG A;  2KE0 A;  3KAG A;  4J4N A;  4LAX A;  4ODP A;  2MLZ A;  4JFI A;  3NI6 A;  1N1A A;  3VAW A;  4JYS A;  5I98 A;  4DRO A;  1M5Y A;  4TW8 A;  4DIP A;  3CGM A;  1FJD A;  2DG3 A;  2MNT A;  2PPO A;  1D7I A;  3KAD A;  5HT1 A;  1JNS A;  4U85 A;  1FD9 A;  1Y0O A;  4JFL A;  2XP9 A;  4ITZ A;  2PPP A;  1BKF A;  3MDY B;  3O5M A;  2XP6 A;  1J4R A;  3O5Q A;  4IQC A;  4DRK A;  1J6Y A;  1QPF A;  3TC5 A;  4JFK A;  5BXJ A;  1KT0 A;  3KAC A;  1F8A B;  2N87 A;  1Q6U A;  3UQI A;  3IHZ A;  4ODM A;  2ITK A;  4C02 B;  5J6E A;  2XPA A;  1FKR A;  4ODL A;  2F2D A;  2KFW A;  2AWG A;  4W9Q A;  1R9H A;  3OOB A;  2VN1 A;  3PRB A;  2ZQU A;  3JYM A;  3O5L A;  4W9O A;  3GPK A;  3PA7 A;  3O5E A;  4U84 A;  2XP5 A;  3KZ7 A;  1J4I A;  1NMV A;  2ZQV A;  4O2T A;  3O5R A;  4QT2 A;  2MPH A;  2PV1 A;  4GGQ A;  5HKG A;  4N19 A;  3KAI A;  2PV2 A;  2ZQT A;  1Q6I A;  1D7J A;  2LJ4 A;  2PPN A;  1EQ3 A;  3O5F A;  4TNS A;  4DZ3 A;  2DG4 A;  4TW6 A;  1TCO C;  1NMW A;  4DRQ A;  3O5G A;  2M2A A;  1FKB A;  1YW5 A;  4DT4 A;  1HXV A;  4DH0 A;  2LGO A;  4DRN A;  2VCD A;  4DRM A;  2Y78 A;  2M08 A;  2RQS A;  3UF8 A;  3LUO A;  2ZQS A;  2MF9 A;  2ZR4 A;  3EY6 A;  3UI4 A;  3UI5 A;  4J4O A;  3IKG A;  1ZCN A;  1D7H A;  1ZK6 A;  2XP7 A;  4DRH A;  5HW7 A;  2RUD A;  1EYM A;  1FKK A;  4JFJ A;  3JXV A;  2F21 A;  2L2S A;  4W9P A;  1FKJ A;  1QZ2 A;  1W26 A;  4IPX A;  2ZR5 A;  3NTP A;  1ROT A;  1FAP A;  1Q6H A;  1PIN A;  1FKD A;  1FKI A;  3CGN A;  4U86 A;  3RFW A;  1JVW A;  2RSE A;  2XPB A;  4ODR A;  2LPV A;  1Q1C A;  2UZ5 A;  4TW7 A;  1FKL A;  1BL4 A;  4G2P A;  3FAP A;  2XP4 A;  5HW8 A;  3I6C A;  5HWB A;  1KT1 A;  4LAY A; 
#chains in the Genus database with same CATH topology
 2F4E A;  2QF8 A;  5HBF A;  1HKM A;  1JNT A;  4ODO A;  2AOS A;  5DO2 A;  2P4V A;  3TCZ A;  1LJY A;  4WKH A;  1QPL A;  2RUC A;  4LAV A;  1H0G A;  4ZS6 A;  4R5E A;  3WH0 A;  4MPK A;  2MLX A;  2YBU A;  2XP3 A;  1CTN A;  1FKF A;  3IK8 A;  1NWS A;  2OFN A;  3KCE A;  2RUR A;  3ARU A;  1C9H A;  1JND A;  4TX0 A;  4LAW A;  3O5P A;  3PRD A;  3BMB A;  2KR7 A;  1LG2 A;  1XHG A;  3KAH A;  4ODK A;  3UI6 A;  1NH6 A;  1LG1 A;  1FKT A;  1ZBK A;  2M1I A;  1L1P A;  3ARP A;  4P8U A;  4J4N A;  4HBE A;  4JFI A;  4MNK A;  3G6L A;  1OGB A;  3FXY A;  3BXW A;  4DIP A;  3CGM A;  1LQ0 A;  2DG3 A;  4L3N A;  1W1T A;  2IUZ A;  1Y0O A;  4JFL A;  3CHE A;  4ITZ A;  2PPP A;  3O5Q A;  2XP6 A;  3GU0 A;  4DRK A;  1K9T A;  1KT0 A;  1E6P A;  3KAC A;  4WKA A;  1WB0 A;  4C02 B;  5J6E A;  2ITK A;  1FKR A;  2F2D A;  1E15 A;  2AWG A;  3AS3 A;  2O92 A;  3PRB A;  4HAR A;  2DSW A;  4S3J A;  1NMV A;  2ZQV A;  1HKJ A;  4Q7N A;  1EDQ A;  1NWR A;  1NMW A;  4P8V A;  2M2A A;  1HXV A;  1YW5 A;  4DT4 A;  1RD6 A;  2Y78 A;  2M08 A;  2YBT A;  2ZQS A;  2MF9 A;  1JNE A;  2B5U B;  4J4O A;  3ARR A;  1ZCN A;  1D7H A;  3WD0 A;  2XP7 A;  2B31 A;  4WIW A;  1W26 A;  1W9V A;  2ZR5 A;  1H0I A;  1E6Z A;  3AS2 A;  3CHF A;  1LL6 A;  1JVW A;  1LL4 A;  2XPB A;  2UZ5 A;  1IX5 A;  2XP4 A;  4AY1 A;  4LAY A;  4LGX A;  4Z2H A;  1J4H A;  2A3E A;  1E44 A;  1B6C A;  3O5I A;  1P5Q A;  3ODK A;  3WD2 A;  2XP8 A;  3H9R B;  3B9A A;  3O5K A;  3KAB A;  5HW6 A;  2LKN A;  3CHC A;  2IF4 A;  2WLY A;  2G41 A;  2MLY A;  4Z2J A;  3W4R A;  1EIB A;  1WNO A;  3WL1 A;  2ZR6 A;  3WD1 A;  2RUQ A;  3UQB A;  3ARO A;  3ARV A;  4BF8 A;  1W1Y A;  3WKZ A;  3KAF A;  4G50 A;  1ZL1 A;  1FKS A;  3ALG A;  3UQA A;  3JYJ A;  5DIU A;  1ROU A;  4DRI A;  2K8I A;  1A7X A;  1W9P A;  4IQ2 A;  3B9D A;  1YAT A;  1NWT A;  4TYO A;  5GPR A;  2KE0 A;  4ODP A;  1N1A A;  4JYS A;  2PN0 A;  5I98 A;  4DRO A;  1FJD A;  1X6N A;  2MNT A;  1JNS A;  2XP9 A;  3O5M A;  3B8S A;  4IQC A;  1QPF A;  4JFK A;  1F8A B;  3IHZ A;  2KFW A;  3EIP A;  3GTY X;  3JYM A;  4KR0 B;  3GPK A;  4U84 A;  1J4I A;  4QT2 A;  2MPH A;  4WKF A;  3WL0 A;  1EQ3 A;  2DT3 A;  3O5F A;  4TW6 A;  1TCO C;  1ZB5 A;  2DT2 A;  2VCD A;  3ARX A;  3CZ8 A;  3LUO A;  2ZR4 A;  3EY6 A;  3RM8 A;  3UI5 A;  3IKG A;  1ZK6 A;  5JH8 A;  1ITX A;  4DRH A;  3WQV A;  1EYM A;  1FKK A;  1W1V A;  2L2S A;  2EUL A;  4UDM A;  4IT6 A;  4P8W A;  1O6I A;  1Q6H A;  1FKI A;  2RSE A;  4ODR A;  4TW7 A;  2LPV A;  1GRJ A;  5HWB A;  3QOK A;  1FKG A;  4FN2 A;  2A3C A;  4PTM A;  4DWS D;  3ARZ A;  5HUA A;  4MNM A;  3O5O A;  5GPG A;  3RME A;  2FAP A;  1F40 A;  2KGJ A;  2D9F A;  2KO7 A;  1SR0 A;  3ART A;  4ODQ A;  4DWS C;  4FAP A;  3PRA A;  2KI3 A;  4DRP A;  3ARQ A;  2PBC A;  4GIV A;  4QT3 A;  3WD4 A;  5DF0 A;  1EHN A;  4NNR A;  2JZV A;  3TDB A;  4ZPT R;  3O5J A;  1FKH A;  5B8I C;  2WLZ A;  2ETN A;  4MAV A;  4DWS B;  4ODN A;  1VF8 A;  5GQB A;  4QIB A;  1TFV A;  4QZV B;  1UR9 A;  3O5D A;  5HTG A;  1NSG A;  3KAG A;  1ZU8 A;  3ARS A;  4TW8 A;  1XRV A;  2PPO A;  1WAW A;  4HBO A;  1FD9 A;  5DEZ A;  1HKI A;  1ZBW A;  1J6Y A;  3TC5 A;  1GOI A;  1Q6U A;  4W9Q A;  3OOB A;  2VN1 A;  2ZQU A;  3O5L A;  2OLH A;  4W9O A;  4O2T A;  3O5R A;  1HJV A;  2PV1 A;  2PV2 A;  2ZQT A;  2LJ4 A;  1ZBV A;  4TNS A;  2O9O A;  4DRQ A;  2F23 A;  4DH0 A;  2LGO A;  3WIJ A;  2DSU A;  2RQS A;  3UF8 A;  3UI4 A;  1HKK A;  3AS1 A;  4JFJ A;  1SYT A;  2F21 A;  3JXV A;  4W9P A;  4Z2K A;  4MTV A;  3NTP A;  3RM4 A;  1FAP A;  4URI A;  1PIN A;  1FKD A;  3CGN A;  3RFW A;  1Q1C A;  1FKL A;  1BL4 A;  5HW8 A;  4ODM A;  1E9L A;  3CHD A;  3AS0 A;  4WJX A;  3ARY A;  3RGC A;  4R0X A;  3ALF A;  3OA5 A;  4MGV A;  4P8X A;  2A3B A;  4S3K A;  4DRJ A;  1D6O A;  2A3A A;  1PBK A;  2Q5A A;  2DSV A;  4IT4 A;  1GUV A;  2G8Z A;  3B9E A;  1KFW A;  1T11 A;  3NRK A;  3IKD A;  2DG9 A;  3RM9 A;  5HWC A;  5DIT A;  4MSP A;  4ZPV R;  4JFM A;  4DWS A;  3FY1 A;  1NWU A;  4XAK A;  3WD3 A;  4DZ2 A;  2FKE A;  5D75 A;  1HJW A;  3B7X A;  2PV3 A;  1U79 A;  1OGG A;  5DIV A;  4LAX A;  2MLZ A;  3NI6 A;  3VAW A;  2WM0 A;  1W9U A;  1M5Y A;  4KQZ A;  4ZPW R;  1D7I A;  3KAD A;  5HT1 A;  1D2K A;  4U85 A;  2DT1 A;  2DPE A;  1BKF A;  3MDY B;  1J4R A;  4Z2G A;  1LL7 A;  5BXJ A;  2N87 A;  4MNL A;  3UQI A;  1HJX A;  2XPA A;  3CH9 A;  4L72 B;  4ODL A;  4ML4 A;  2WK2 A;  3WQW A;  1R9H A;  1ZBC A;  4NSB A;  1E6N A;  3PA7 A;  3O5E A;  4WK9 A;  2XP5 A;  3KZ7 A;  4W5U A;  5HKG A;  4GGQ A;  4N19 A;  3KAI A;  4Q22 A;  4MNJ A;  1GPF A;  3PR9 A;  2PI6 A;  1OWQ A;  1Q6I A;  1D7J A;  2PPN A;  4DZ3 A;  2DG4 A;  3O5G A;  1FKB A;  3AQU A;  1E6R A;  4DRN A;  4DRM A;  4NZC A;  4Z2L A;  3G6M A;  3ARW A;  1W1P A;  2DT0 A;  2FDM A;  5HW7 A;  2RUD A;  1FFQ A;  2ESC A;  1FKJ A;  1QZ2 A;  4IPX A;  4Z2I A;  1ROT A;  1JCH B;  1FFR A;  4U86 A;  1X6L A;  4G2P A;  3FAP A;  3I6C A;  2DSZ A;  1KT1 A;  1UR8 A; 
#chains in the Genus database with same CATH homology
 2F4E A;  2QF8 A;  5HBF A;  1HKM A;  1JNT A;  4ODO A;  2AOS A;  5DO2 A;  3TCZ A;  1LJY A;  4WKH A;  1QPL A;  2RUC A;  4LAV A;  1H0G A;  4ZS6 A;  4R5E A;  3WH0 A;  4MPK A;  2MLX A;  2YBU A;  2XP3 A;  1CTN A;  1FKF A;  3IK8 A;  1NWS A;  2OFN A;  3KCE A;  2RUR A;  3ARU A;  1C9H A;  1JND A;  4TX0 A;  4LAW A;  3O5P A;  3PRD A;  2KR7 A;  1LG2 A;  1XHG A;  3KAH A;  4ODK A;  3UI6 A;  1NH6 A;  1LG1 A;  1FKT A;  1ZBK A;  2M1I A;  1L1P A;  3ARP A;  4P8U A;  4J4N A;  4HBE A;  4JFI A;  4MNK A;  3G6L A;  1OGB A;  3FXY A;  3BXW A;  4DIP A;  3CGM A;  1LQ0 A;  2DG3 A;  4L3N A;  1W1T A;  2IUZ A;  1Y0O A;  4JFL A;  3CHE A;  4ITZ A;  2PPP A;  3O5Q A;  2XP6 A;  4DRK A;  1K9T A;  1KT0 A;  1E6P A;  3KAC A;  4WKA A;  1WB0 A;  4C02 B;  5J6E A;  2ITK A;  1FKR A;  2F2D A;  1E15 A;  2AWG A;  3AS3 A;  2O92 A;  3PRB A;  4HAR A;  2DSW A;  4S3J A;  1NMV A;  2ZQV A;  1HKJ A;  4Q7N A;  1EDQ A;  1NWR A;  1NMW A;  4P8V A;  2M2A A;  1HXV A;  1YW5 A;  4DT4 A;  1RD6 A;  2Y78 A;  2M08 A;  2YBT A;  2ZQS A;  2MF9 A;  1JNE A;  4J4O A;  3ARR A;  1ZCN A;  1D7H A;  3WD0 A;  2XP7 A;  2B31 A;  4WIW A;  1W26 A;  1W9V A;  2ZR5 A;  1H0I A;  1E6Z A;  3AS2 A;  3CHF A;  1LL6 A;  1JVW A;  1LL4 A;  2XPB A;  2UZ5 A;  1IX5 A;  2XP4 A;  4AY1 A;  4LAY A;  4LGX A;  4Z2H A;  1J4H A;  2A3E A;  1B6C A;  3O5I A;  1P5Q A;  3ODK A;  3WD2 A;  2XP8 A;  3H9R B;  3B9A A;  3O5K A;  3KAB A;  5HW6 A;  2LKN A;  3CHC A;  2IF4 A;  2WLY A;  2G41 A;  2MLY A;  4Z2J A;  3W4R A;  1EIB A;  1WNO A;  3WL1 A;  2ZR6 A;  3WD1 A;  2RUQ A;  3UQB A;  3ARO A;  3ARV A;  4BF8 A;  1W1Y A;  3WKZ A;  3KAF A;  4G50 A;  1ZL1 A;  1FKS A;  3ALG A;  3UQA A;  3JYJ A;  5DIU A;  1ROU A;  4DRI A;  2K8I A;  1A7X A;  1W9P A;  4IQ2 A;  3B9D A;  1YAT A;  1NWT A;  4TYO A;  5GPR A;  2KE0 A;  4ODP A;  1N1A A;  4JYS A;  5I98 A;  4DRO A;  1FJD A;  1X6N A;  2MNT A;  1JNS A;  2XP9 A;  3O5M A;  3B8S A;  4IQC A;  1QPF A;  4JFK A;  1F8A B;  3IHZ A;  2KFW A;  3JYM A;  4KR0 B;  3GPK A;  4U84 A;  1J4I A;  4QT2 A;  2MPH A;  4WKF A;  3WL0 A;  1EQ3 A;  2DT3 A;  3O5F A;  4TW6 A;  1TCO C;  1ZB5 A;  2DT2 A;  2VCD A;  3ARX A;  3CZ8 A;  3LUO A;  2ZR4 A;  3EY6 A;  3RM8 A;  3UI5 A;  3IKG A;  1ZK6 A;  5JH8 A;  1ITX A;  4DRH A;  3WQV A;  1EYM A;  1FKK A;  1W1V A;  2L2S A;  4IT6 A;  4P8W A;  1O6I A;  1Q6H A;  1FKI A;  2RSE A;  4ODR A;  4TW7 A;  2LPV A;  5HWB A;  3QOK A;  1FKG A;  4FN2 A;  2A3C A;  4PTM A;  4DWS D;  3ARZ A;  5HUA A;  4MNM A;  3O5O A;  5GPG A;  3RME A;  2FAP A;  1F40 A;  2KGJ A;  2D9F A;  2KO7 A;  1SR0 A;  3ART A;  4ODQ A;  4DWS C;  4FAP A;  3PRA A;  2KI3 A;  4DRP A;  3ARQ A;  2PBC A;  4GIV A;  4QT3 A;  3WD4 A;  5DF0 A;  1EHN A;  4NNR A;  2JZV A;  3TDB A;  4ZPT R;  3O5J A;  1FKH A;  5B8I C;  2WLZ A;  4MAV A;  4DWS B;  4ODN A;  1VF8 A;  5GQB A;  4QIB A;  1TFV A;  4QZV B;  1UR9 A;  3O5D A;  5HTG A;  1NSG A;  3KAG A;  1ZU8 A;  3ARS A;  4TW8 A;  1XRV A;  2PPO A;  1WAW A;  4HBO A;  1FD9 A;  5DEZ A;  1HKI A;  1ZBW A;  1J6Y A;  3TC5 A;  1GOI A;  1Q6U A;  4W9Q A;  3OOB A;  2VN1 A;  2ZQU A;  3O5L A;  2OLH A;  4W9O A;  4O2T A;  3O5R A;  1HJV A;  2PV1 A;  2PV2 A;  2ZQT A;  2LJ4 A;  1ZBV A;  4TNS A;  2O9O A;  4DRQ A;  4DH0 A;  2LGO A;  3WIJ A;  2DSU A;  2RQS A;  3UF8 A;  3UI4 A;  1HKK A;  3AS1 A;  4JFJ A;  1SYT A;  2F21 A;  3JXV A;  4W9P A;  4Z2K A;  4MTV A;  3NTP A;  3RM4 A;  1FAP A;  4URI A;  1PIN A;  1FKD A;  3CGN A;  3RFW A;  1Q1C A;  1FKL A;  1BL4 A;  5HW8 A;  4ODM A;  1E9L A;  3CHD A;  3AS0 A;  4WJX A;  3ARY A;  3RGC A;  4R0X A;  3ALF A;  3OA5 A;  4MGV A;  4P8X A;  2A3B A;  4S3K A;  4DRJ A;  1D6O A;  2A3A A;  1PBK A;  2Q5A A;  2DSV A;  4IT4 A;  1GUV A;  2G8Z A;  3B9E A;  1KFW A;  1T11 A;  3NRK A;  3IKD A;  2DG9 A;  3RM9 A;  5HWC A;  5DIT A;  4MSP A;  4ZPV R;  4JFM A;  4DWS A;  3FY1 A;  1NWU A;  4XAK A;  3WD3 A;  4DZ2 A;  2FKE A;  5D75 A;  1HJW A;  3B7X A;  2PV3 A;  1U79 A;  1OGG A;  5DIV A;  4LAX A;  2MLZ A;  3NI6 A;  3VAW A;  2WM0 A;  1W9U A;  1M5Y A;  4KQZ A;  4ZPW R;  1D7I A;  3KAD A;  5HT1 A;  1D2K A;  4U85 A;  2DT1 A;  2DPE A;  1BKF A;  3MDY B;  1J4R A;  4Z2G A;  1LL7 A;  5BXJ A;  2N87 A;  4MNL A;  3UQI A;  1HJX A;  2XPA A;  3CH9 A;  4L72 B;  4ODL A;  4ML4 A;  2WK2 A;  3WQW A;  1R9H A;  1ZBC A;  4NSB A;  1E6N A;  3PA7 A;  3O5E A;  4WK9 A;  2XP5 A;  3KZ7 A;  4W5U A;  5HKG A;  4GGQ A;  4N19 A;  3KAI A;  4Q22 A;  4MNJ A;  1GPF A;  3PR9 A;  2PI6 A;  1OWQ A;  1Q6I A;  1D7J A;  2PPN A;  4DZ3 A;  2DG4 A;  3O5G A;  1FKB A;  3AQU A;  1E6R A;  4DRN A;  4DRM A;  4NZC A;  4Z2L A;  3G6M A;  3ARW A;  1W1P A;  2DT0 A;  2FDM A;  5HW7 A;  2RUD A;  1FFQ A;  2ESC A;  1FKJ A;  1QZ2 A;  4IPX A;  4Z2I A;  1ROT A;  1FFR A;  4U86 A;  1X6L A;  4G2P A;  3FAP A;  3I6C A;  2DSZ A;  1KT1 A;  1UR8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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