4DROA

Evaluation of synthetic fk506 analogs as ligands for fkbp51 and fkbp52: complex of fkbp51 with (1r)-3-(3,4-dimethoxyphenyl)-1-phenylpropyl (2s)-1-{[(1r,2s)-2-ethyl-1-hydroxycyclohexyl](oxo)acetyl}piperidine-2-carboxylate
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
128
structure length
128
Chain Sequence
GAPATVTEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52.
pubmed doi rcsb
molecule keywords Peptidyl-prolyl cis-trans isomerase FKBP5
molecule tags Isomerase
source organism Homo sapiens
total genus 36
structure length 128
sequence length 128
ec nomenclature ec 5.2.1.8: Peptidylprolyl isomerase.
pdb deposition date 2012-02-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00254 FKBP_C FKBP-type peptidyl-prolyl cis-trans isomerase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.50.40 Alpha Beta Roll Chitinase A; domain 3 Chitinase A; domain 3 4droA00
2IF4A 4IPXA 3WH0A 4DRJA 1D6OA 3JXVA 2XP8A 3KACA 4LAYA 2FKEA 3KCEA 3NI6A 4G50A 3TCZA 4ODOA 2KO7A 4TW6A 4U84A 3CGMA 3KAFA 3LUOA 4DRKA 1QZ2A 5DIVA 1Q6IA 3RGCA 2RURA 2ZR6A 1QPLA 2PPOA 1ZCNA 2PPPA 3IK8A 1D7IA 1FKDA 3O5RA 2PV3A 3UI5A 5BXJA 4JFIA 5B8IC 3O5PA 4DRMA 4DRQA 1FKRA 1FKSA 1JNSA 1A7XA 5HTGA 2F2DA 2DG3A 1FKBA 1FKGA 4NNRA 3I6CA 3B7XA 2KI3A 1ROTA 2PV2A 2UZ5A 4BF8A 5D75A 2ITKA 4ODLA 2ZQSA 2L2SA 2OFNA 4JYSA 5HT1A 2M1IA 2MPHA 2MLYA 1FKTA 3NRKA 3O5GA 4IQ2A 2LJ4A 2RSEA 5HWCA 2LGOA 2MNTA 3UI6A 2PPNA 5I98A 4R0XA 3UQAA 1FKHA 3IKDA 3ODKA 1L1PA 4C02B 3CGNA 4IQCA 4O2TA 3UI4A 1W26A 2ZQTA 4QT3A 2VCDA 3GPKA 2MLZA 1QPFA 2MF9A 2PV1A 1FKJA 4TYOA 2F21A 2LPVA 5HW6A 5HWBA 1FAPA 2M08A 2Y78A 4G2PA 4MGVA 1KT1A 1BL4A 2K8IA 2JZVA 2M2AA 5DIUA 4J4NA 1YW5A 2XPBA 3KADA 3OOBA 4JFKA 3EY6A 3O5IA 3TDBA 3O5LA 3PRBA 4ODMA 2PBCA 3FAPA 4LAVA 1J4RA 3O5MA 3O5FA 2LKNA 4DRNA 4DZ2A 1P5QA 4TW8A 1M5YA 1HXVA 1F40A 2RQSA 4ITZA 3JYJA 1N1AA 4N19A 1KT0A 2RUDA 1ROUA 4JFJA 4QIBA 2ZR5A 4DIPA 2F4EA 2D9FA 2XP3A 3MDYB 1J4HA 1D7HA 1Q6HA 1FKLA 2VN1A 4DZ3A 3KZ7A 1R9HA 3NTPA 1PINA 4DH0A 3UF8A 1EQ3A 4ODPA 4DRIA 2XP5A 3KABA 5HW8A 3PA7A 2N87A 2RUCA 3JYMA 4FN2A 4LAXA 2ZQUA 3H9RB 3KAGA 2ZR4A 4DT4A 2Q5AA 5HUAA 2RUQA 3VAWA 1FKIA 2DG4A 4ODRA 1YATA 2KR7A 1Q6UA 4J4OA 1U79A 1F8AB 1FD9A 4DROA 4W9OA 5HKGA 4LAWA 3UQBA 3KAIA 1J6YA 4U85A 3O5JA 1FKKA 3PRDA 2KE0A 4ODNA 2XP9A 4QT2A 4TX0A 4DRHA 1FKFA 3RFWA 1ZK6A 5HW7A 4W9QA 1JNTA 1NSGA 2AWGA 2DG9A 1J4IA 2MLXA 1C9HA 2XP4A 4JFMA 2KGJA 3O5EA 1T11A 1JVWA 4GGQA 4U86A 3UQIA 4FAPA 1D7JA 1TCOC 1NMWA 1Q1CA 4JFLA 2XP6A 2XPAA 1B6CA 3O5QA 5J6EA 2ZQVA 4TW7A 1PBKA 2FAPA 3IKGA 4GIVA 4TNSA 3TC5A 1NMVA 3KAHA 3O5DA 2KFWA 2XP7A 3IHZA 5DITA 3O5KA 5GPGA 1FJDA 4ODQA 4DRPA 1Y0OA 4ODKA 3O5OA 4MSPA 1EYMA 1BKFA 4W9PA
chains in the Genus database with same CATH superfamily
4IPXA 1XRVA 3WIJA 3CHFA 1W1VA 2XP8A 2KO7A 4TW6A 3CGMA 1QZ2A 2RURA 2ZR6A 1QPLA 2PPOA 1FKDA 1XHGA 3O5RA 2PV3A 5BXJA 4JFIA 3O5PA 1RD6A 4DRQA 1A7XA 1KFWA 2F2DA 3B9AA 2PV2A 1K9TA 4ODLA 4L3NA 2ZQSA 4MTVA 3WL1A 2ETNA 2LGOA 5I98A 2B31A 4R0XA 1FKHA 4AY1A 4C02B 4IT4A 4NSBA 1W26A 3GPKA 2MLZA 1QPFA 2MF9A 4TYOA 5HW6A 1FAPA 3WD0A 4J4NA 2DSWA 4MNJA 1FFRA 3CHCA 4JFKA 3ARRA 3AS0A 4W5UA 1E9LA 3ARXA 1X6NA 4DZ2A 1E6ZA 1M5YA 4ITZA 1KT0A 2RUDA 3B8SA 4DIPA 5DEZA 3MDYB 1J4HA 1D7HA 4WJXA 4DZ3A 3NTPA 1EQ3A 1WNOA 3UF8A 4ODPA 1NWUA 2WK2A 2WM0A 3JYMA 5GPRA 5HUAA 2RUQA 2G8ZA 3PR9A 4J4OA 1F8AB 1FD9A 3OA5A 3O5JA 3RM9A 3PRDA 2KE0A 4Q7NA 4TX0A 4DRHA 1FKFA 5HW7A 1NSGA 2MLXA 1C9HA 1W9VA 2KGJA 4U86A 3GU0A 2XPAA 3EIPA 2ZQVA 1ZBCA 2KFWA 4P8XA 1FJDA 1W1PA 4DRPA 3ARPA 3AS1A 4W9PA 2IF4A 3JXVA 1X6LA 2G41A 3G6LA 2A3CA 4G50A 1SYTA 2ESCA 3CZ8A 2DT2A 1LG1A 2DPEA 1SR0A 1GRJA 1GPFA 1LL6A 1ZCNA 3UI5A 1LG2A 1FKRA 4UDMA 5HTGA 1FKBA 3ARYA 1LL7A 1NWRA 2DT1A 3I6CA 1ROTA 2UZ5A 3WD1A 2L2SA 2OFNA 4MNLA 4Z2KA 2MPHA 4Z2JA 1HKKA 5HWCA 3UI6A 4PTMA 3ODKA 4QZVB 3UI4A 2PV1A 1ZU8A 4G2PA 4MGVA 1BL4A 1NWTA 4NZCA 3KADA 4WKAA 2IUZA 3EY6A 1OGBA 1HJVA 3PRBA 4LAVA 1J4RA 3O5FA 2P4VA 2LKNA 1OWQA 3PRAA 1P5QA 2F23A 4TW8A 3JYJA 4HBEA 1N1AA 4XAKA 1GUVA 1TFVA 1FKLA 2VN1A 3KZ7A 4DH0A 4DRIA 4KQZA 2XP5A 5HW8A 4FN2A 2N87A 4LAXA 3WD3A 1JNEA 2ZQUA 3WD4A 5DF0A 1YATA 2KR7A 4ZPTR 1J6YA 4DROA 5HKGA 4W9OA 3UQBA 1O6IA 1W9UA 3ALGA 4ODNA 4QT2A 4DWSA 4ZPWR 1HJXA 3AQUA 3RFWA 1ZK6A 2AOSA 4W9QA 1ZBWA 2AWGA 2DG9A 2A3EA 2XP4A 2O92A 4JFMA 4GGQA 3BXWA 3UQIA 1TCOC 1WB0A 3O5QA 5J6EA 3TC5A 1W1TA 1ZBVA 3KAHA 5DITA 2XP7A 4P8VA 4S3JA 5GPGA 4ODQA 1W9PA 1E15A 2O9OA 4ZPVR 4ODKA 3O5OA 1JCHB 1EDQA 4DRJA 3WH0A 1VF8A 1D6OA 4Q22A 2A3BA 4LAYA 2FKEA 3KCEA 3WD2A 3TCZA 4ODOA 4U84A 4WIWA 3KAFA 3LUOA 1ZL1A 4DRKA 5DIVA 3RGCA 2PPPA 1D7IA 3WQWA 4DWSC 3CHEA 5B8IC 1JNSA 1FKSA 3ARVA 2EULA 4KR0B 1FKGA 2DSVA 2PI6A 2YBTA 1H0IA 4S3KA 5GQBA 5HT1A 3RMEA 1E44A 1NH6A 1FKTA 4IQ2A 2LJ4A 2RSEA 2MNTA 3BMBA 2PPNA 3FXYA 4HBOA 3RM4A 1E6NA 1L1PA 3UQAA 5DO2A 4Z2GA 3CGNA 4IQCA 3FY1A 2VCDA 2B5UB 2A3AA 2F21A 5HWBA 2M08A 1D2KA 1KT1A 5DIUA 2K8IA 1CTNA 3AROA 3O5IA 3TDBA 3O5LA 2PBCA 1OGGA 1FFQA 2WLYA 4R5EA 2RQSA 4MAVA 1ROUA 4JFJA 4QIBA 2ZR5A 4ML4A 3ALFA 2XP3A 4Z2LA 2FDMA 1ITXA 3G6MA 2DSZA 3KABA 3PA7A 2RUCA 3B9EA 3H9RB 4DT4A 3VAWA 1FKIA 3WQVA 3AS2A 4ODRA 3KAIA 4U85A 4MNKA 4ZS6A 3WKZA 1JNTA 2WLZA 1J4IA 3ARWA 1IX5A 1T11A 1JVWA 3CHDA 1D7JA 1NMWA 1Q1CA 4MNMA 2XP6A 1B6CA 2DT0A 5HBFA 1PBKA 2FAPA 4GIVA 4TNSA 1NMVA 3O5DA 3IHZA 1EIBA 3O5KA 1E6RA 1EYMA 1BKFA 4N19A 2DSUA 3ARSA 3KACA 3NI6A 4L72B 1Q6IA 1HKMA 3ARZA 3IK8A 2OLHA 4DRMA 1W1YA 2DG3A 4Z2IA 4NNRA 1EHNA 3B7XA 2KI3A 4BF8A 5D75A 2ITKA 4IT6A 4JYSA 2M1IA 2MLYA 3W4RA 3NRKA 3O5GA 1UR8A 2QF8A 4HARA 3WL0A 4MPKA 3IKDA 1NWSA 4O2TA 1E6PA 1ZB5A 2ZQTA 4QT3A 1FKJA 2LPVA 1HKIA 5JH8A 2Y78A 1UR9A 2JZVA 2M2AA 1ZBKA 1YW5A 2XPBA 3OOBA 4ODMA 3FAPA 3O5MA 1HKJA 4DRNA 4WKHA 3RM8A 1HXVA 1F40A 1LQ0A 4WK9A 2F4EA 1HJWA 3AS3A 2D9FA 1Q6HA 1LL4A 1R9HA 1PINA 3GTYX 4DWSD 1JNDA 3ARUA 3KAGA 4LGXA 2ZR4A 2Q5AA 1LJYA 2DG4A 1GOIA 4DWSB 3QOKA 1Q6UA 1U79A 4LAWA 3ARTA 3CH9A 1FKKA 3ARQA 4P8WA 4P8UA 2XP9A 3B9DA 1H0GA 1WAWA 3O5EA 4URIA 4FAPA 4WKFA 4Z2HA 2DT3A 4JFLA 4TW7A 3IKGA 2PN0A 1Y0OA 2YBUA 4MSPA
chains in the Genus database with same CATH topology
4IPXA 1XRVA 3WIJA 3CHFA 1W1VA 2XP8A 2KO7A 4TW6A 3CGMA 1QZ2A 2RURA 2ZR6A 1QPLA 2PPOA 1FKDA 1XHGA 3O5RA 2PV3A 5BXJA 4JFIA 3O5PA 1RD6A 4DRQA 1A7XA 1KFWA 2F2DA 3B9AA 2PV2A 1K9TA 4ODLA 4L3NA 2ZQSA 4MTVA 3WL1A 2LGOA 5I98A 2B31A 4R0XA 1FKHA 4AY1A 4C02B 4IT4A 4NSBA 1W26A 3GPKA 2MLZA 1QPFA 2MF9A 4TYOA 5HW6A 1FAPA 3WD0A 4J4NA 2DSWA 4MNJA 1FFRA 3CHCA 4JFKA 3ARRA 3AS0A 4W5UA 1E9LA 3ARXA 1X6NA 4DZ2A 1E6ZA 1M5YA 4ITZA 1KT0A 2RUDA 3B8SA 4DIPA 5DEZA 3MDYB 1J4HA 1D7HA 4WJXA 4DZ3A 3NTPA 1EQ3A 1WNOA 3UF8A 4ODPA 1NWUA 2WK2A 2WM0A 3JYMA 5GPRA 5HUAA 2RUQA 2G8ZA 3PR9A 4J4OA 1F8AB 1FD9A 3OA5A 3O5JA 3RM9A 3PRDA 2KE0A 4Q7NA 4TX0A 4DRHA 1FKFA 5HW7A 1NSGA 2MLXA 1C9HA 1W9VA 2KGJA 4U86A 2XPAA 2ZQVA 1ZBCA 2KFWA 4P8XA 1FJDA 1W1PA 4DRPA 3ARPA 3AS1A 4W9PA 2IF4A 3JXVA 1X6LA 2G41A 3G6LA 2A3CA 4G50A 1SYTA 2ESCA 3CZ8A 2DT2A 1LG1A 2DPEA 1SR0A 1GPFA 1LL6A 1ZCNA 3UI5A 1LG2A 1FKRA 5HTGA 1FKBA 3ARYA 1LL7A 1NWRA 2DT1A 3I6CA 1ROTA 2UZ5A 3WD1A 2L2SA 2OFNA 4MNLA 4Z2KA 2MPHA 4Z2JA 1HKKA 5HWCA 3UI6A 4PTMA 3ODKA 4QZVB 3UI4A 2PV1A 1ZU8A 4G2PA 4MGVA 1BL4A 1NWTA 4NZCA 3KADA 4WKAA 2IUZA 3EY6A 1OGBA 1HJVA 3PRBA 4LAVA 1J4RA 3O5FA 2LKNA 1OWQA 3PRAA 1P5QA 4TW8A 3JYJA 4HBEA 1N1AA 4XAKA 1GUVA 1TFVA 1FKLA 2VN1A 3KZ7A 4DH0A 4DRIA 4KQZA 2XP5A 5HW8A 4FN2A 2N87A 4LAXA 3WD3A 1JNEA 2ZQUA 3WD4A 5DF0A 1YATA 2KR7A 4ZPTR 1J6YA 4DROA 5HKGA 4W9OA 3UQBA 1O6IA 1W9UA 3ALGA 4ODNA 4QT2A 4DWSA 4ZPWR 1HJXA 3AQUA 3RFWA 1ZK6A 2AOSA 4W9QA 1ZBWA 2AWGA 2DG9A 2A3EA 2XP4A 2O92A 4JFMA 4GGQA 3BXWA 3UQIA 1TCOC 1WB0A 3O5QA 5J6EA 3TC5A 1W1TA 1ZBVA 3KAHA 5DITA 2XP7A 4P8VA 4S3JA 5GPGA 4ODQA 1W9PA 1E15A 2O9OA 4ZPVR 4ODKA 3O5OA 1EDQA 4DRJA 3WH0A 1VF8A 1D6OA 4Q22A 2A3BA 4LAYA 2FKEA 3KCEA 3WD2A 3TCZA 4ODOA 4U84A 4WIWA 3KAFA 3LUOA 1ZL1A 4DRKA 5DIVA 3RGCA 2PPPA 1D7IA 3WQWA 4DWSC 3CHEA 5B8IC 1JNSA 1FKSA 3ARVA 4KR0B 1FKGA 2DSVA 2PI6A 2YBTA 1H0IA 4S3KA 5GQBA 5HT1A 3RMEA 1NH6A 1FKTA 4IQ2A 2LJ4A 2RSEA 2MNTA 3FXYA 2PPNA 4HBOA 3RM4A 1E6NA 1L1PA 3UQAA 5DO2A 4Z2GA 3CGNA 4IQCA 3FY1A 2VCDA 2A3AA 2F21A 5HWBA 2M08A 1D2KA 1KT1A 5DIUA 2K8IA 1CTNA 3AROA 3O5IA 3TDBA 3O5LA 2PBCA 1OGGA 1FFQA 2WLYA 4R5EA 2RQSA 4MAVA 1ROUA 4JFJA 4QIBA 2ZR5A 4ML4A 3ALFA 2XP3A 4Z2LA 2FDMA 1ITXA 3G6MA 2DSZA 3KABA 3PA7A 2RUCA 3B9EA 3H9RB 4DT4A 3VAWA 1FKIA 3WQVA 3AS2A 4ODRA 3KAIA 4U85A 4MNKA 4ZS6A 3WKZA 1JNTA 2WLZA 1J4IA 3ARWA 1IX5A 1T11A 1JVWA 3CHDA 1D7JA 1NMWA 1Q1CA 4MNMA 2XP6A 1B6CA 2DT0A 5HBFA 1PBKA 2FAPA 4GIVA 4TNSA 1NMVA 3O5DA 3IHZA 1EIBA 3O5KA 1E6RA 1EYMA 1BKFA 4N19A 2DSUA 3ARSA 3KACA 3NI6A 4L72B 1Q6IA 1HKMA 3ARZA 3IK8A 2OLHA 4DRMA 1W1YA 2DG3A 4Z2IA 4NNRA 1EHNA 3B7XA 2KI3A 4BF8A 5D75A 2ITKA 4IT6A 4JYSA 2M1IA 2MLYA 3W4RA 3NRKA 3O5GA 1UR8A 2QF8A 4HARA 3WL0A 4MPKA 3IKDA 1NWSA 4O2TA 1E6PA 1ZB5A 2ZQTA 4QT3A 1FKJA 2LPVA 1HKIA 5JH8A 2Y78A 1UR9A 2JZVA 2M2AA 1ZBKA 1YW5A 2XPBA 3OOBA 4ODMA 3FAPA 3O5MA 1HKJA 4DRNA 4WKHA 3RM8A 1HXVA 1F40A 1LQ0A 4WK9A 2F4EA 1HJWA 3AS3A 2D9FA 1Q6HA 1LL4A 1R9HA 1PINA 4DWSD 1JNDA 3ARUA 3KAGA 4LGXA 2ZR4A 2Q5AA 1LJYA 2DG4A 1GOIA 4DWSB 3QOKA 1Q6UA 1U79A 4LAWA 3ARTA 3CH9A 1FKKA 3ARQA 4P8WA 4P8UA 2XP9A 3B9DA 1H0GA 1WAWA 3O5EA 4URIA 4FAPA 4WKFA 4Z2HA 2DT3A 4JFLA 4TW7A 3IKGA 1Y0OA 2YBUA 4MSPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IF4 A;  4IPX A;  3WH0 A;  4DRJ A;  1D6O A;  3JXV A;  2XP8 A;  3KAC A;  4LAY A;  2FKE A;  3KCE A;  3NI6 A;  4G50 A;  3TCZ A;  4ODO A;  2KO7 A;  4TW6 A;  4U84 A;  3CGM A;  3KAF A;  3LUO A;  4DRK A;  1QZ2 A;  5DIV A;  1Q6I A;  3RGC A;  2RUR A;  2ZR6 A;  1QPL A;  2PPO A;  1ZCN A;  2PPP A;  3IK8 A;  1D7I A;  1FKD A;  3O5R A;  2PV3 A;  3UI5 A;  5BXJ A;  4JFI A;  5B8I C;  3O5P A;  4DRM A;  4DRQ A;  1FKR A;  1FKS A;  1JNS A;  1A7X A;  5HTG A;  2F2D A;  2DG3 A;  1FKB A;  1FKG A;  4NNR A;  3I6C A;  3B7X A;  2KI3 A;  1ROT A;  2PV2 A;  2UZ5 A;  4BF8 A;  5D75 A;  2ITK A;  4ODL A;  2ZQS A;  2L2S A;  2OFN A;  4JYS A;  5HT1 A;  2M1I A;  2MPH A;  2MLY A;  1FKT A;  3NRK A;  3O5G A;  4IQ2 A;  2LJ4 A;  2RSE A;  5HWC A;  2LGO A;  2MNT A;  3UI6 A;  2PPN A;  5I98 A;  4R0X A;  3UQA A;  1FKH A;  3IKD A;  3ODK A;  1L1P A;  4C02 B;  3CGN A;  4IQC A;  4O2T A;  3UI4 A;  1W26 A;  2ZQT A;  4QT3 A;  2VCD A;  3GPK A;  2MLZ A;  1QPF A;  2MF9 A;  2PV1 A;  1FKJ A;  4TYO A;  2F21 A;  2LPV A;  5HW6 A;  5HWB A;  1FAP A;  2M08 A;  2Y78 A;  4G2P A;  4MGV A;  1KT1 A;  1BL4 A;  2K8I A;  2JZV A;  2M2A A;  5DIU A;  4J4N A;  1YW5 A;  2XPB A;  3KAD A;  3OOB A;  4JFK A;  3EY6 A;  3O5I A;  3TDB A;  3O5L A;  3PRB A;  4ODM A;  2PBC A;  3FAP A;  4LAV A;  1J4R A;  3O5M A;  3O5F A;  2LKN A;  4DRN A;  4DZ2 A;  1P5Q A;  4TW8 A;  1M5Y A;  1HXV A;  1F40 A;  2RQS A;  4ITZ A;  3JYJ A;  1N1A A;  4N19 A;  1KT0 A;  2RUD A;  1ROU A;  4JFJ A;  4QIB A;  2ZR5 A;  4DIP A;  2F4E A;  2D9F A;  2XP3 A;  3MDY B;  1J4H A;  1D7H A;  1Q6H A;  1FKL A;  2VN1 A;  4DZ3 A;  3KZ7 A;  1R9H A;  3NTP A;  1PIN A;  4DH0 A;  3UF8 A;  1EQ3 A;  4ODP A;  4DRI A;  2XP5 A;  3KAB A;  5HW8 A;  3PA7 A;  2N87 A;  2RUC A;  3JYM A;  4FN2 A;  4LAX A;  2ZQU A;  3H9R B;  3KAG A;  2ZR4 A;  4DT4 A;  2Q5A A;  5HUA A;  2RUQ A;  3VAW A;  1FKI A;  2DG4 A;  4ODR A;  1YAT A;  2KR7 A;  1Q6U A;  4J4O A;  1U79 A;  1F8A B;  1FD9 A;  4DRO A;  4W9O A;  5HKG A;  4LAW A;  3UQB A;  3KAI A;  1J6Y A;  4U85 A;  3O5J A;  1FKK A;  3PRD A;  2KE0 A;  4ODN A;  2XP9 A;  4QT2 A;  4TX0 A;  4DRH A;  1FKF A;  3RFW A;  1ZK6 A;  5HW7 A;  4W9Q A;  1JNT A;  1NSG A;  2AWG A;  2DG9 A;  1J4I A;  2MLX A;  1C9H A;  2XP4 A;  4JFM A;  2KGJ A;  3O5E A;  1T11 A;  1JVW A;  4GGQ A;  4U86 A;  3UQI A;  4FAP A;  1D7J A;  1TCO C;  1NMW A;  1Q1C A;  4JFL A;  2XP6 A;  2XPA A;  1B6C A;  3O5Q A;  5J6E A;  2ZQV A;  4TW7 A;  1PBK A;  2FAP A;  3IKG A;  4GIV A;  4TNS A;  3TC5 A;  1NMV A;  3KAH A;  3O5D A;  2KFW A;  2XP7 A;  3IHZ A;  5DIT A;  3O5K A;  5GPG A;  1FJD A;  4ODQ A;  4DRP A;  1Y0O A;  4ODK A;  3O5O A;  4MSP A;  1EYM A;  1BKF A;  4W9P A; 
#chains in the Genus database with same CATH topology
 4IPX A;  1XRV A;  3WIJ A;  3CHF A;  1W1V A;  2XP8 A;  2KO7 A;  4TW6 A;  3CGM A;  1QZ2 A;  2RUR A;  2ZR6 A;  1QPL A;  2PPO A;  1FKD A;  1XHG A;  3O5R A;  2PV3 A;  5BXJ A;  4JFI A;  3O5P A;  1RD6 A;  4DRQ A;  1A7X A;  1KFW A;  2F2D A;  3B9A A;  2PV2 A;  1K9T A;  4ODL A;  4L3N A;  2ZQS A;  4MTV A;  3WL1 A;  2ETN A;  2LGO A;  5I98 A;  2B31 A;  4R0X A;  1FKH A;  4AY1 A;  4C02 B;  4IT4 A;  4NSB A;  1W26 A;  3GPK A;  2MLZ A;  1QPF A;  2MF9 A;  4TYO A;  5HW6 A;  1FAP A;  3WD0 A;  4J4N A;  2DSW A;  4MNJ A;  1FFR A;  3CHC A;  4JFK A;  3ARR A;  3AS0 A;  4W5U A;  1E9L A;  3ARX A;  1X6N A;  4DZ2 A;  1E6Z A;  1M5Y A;  4ITZ A;  1KT0 A;  2RUD A;  3B8S A;  4DIP A;  5DEZ A;  3MDY B;  1J4H A;  1D7H A;  4WJX A;  4DZ3 A;  3NTP A;  1EQ3 A;  1WNO A;  3UF8 A;  4ODP A;  1NWU A;  2WK2 A;  2WM0 A;  3JYM A;  5GPR A;  5HUA A;  2RUQ A;  2G8Z A;  3PR9 A;  4J4O A;  1F8A B;  1FD9 A;  3OA5 A;  3O5J A;  3RM9 A;  3PRD A;  2KE0 A;  4Q7N A;  4TX0 A;  4DRH A;  1FKF A;  5HW7 A;  1NSG A;  2MLX A;  1C9H A;  1W9V A;  2KGJ A;  4U86 A;  3GU0 A;  2XPA A;  3EIP A;  2ZQV A;  1ZBC A;  2KFW A;  4P8X A;  1FJD A;  1W1P A;  4DRP A;  3ARP A;  3AS1 A;  4W9P A;  2IF4 A;  3JXV A;  1X6L A;  2G41 A;  3G6L A;  2A3C A;  4G50 A;  1SYT A;  2ESC A;  3CZ8 A;  2DT2 A;  1LG1 A;  2DPE A;  1SR0 A;  1GRJ A;  1GPF A;  1LL6 A;  1ZCN A;  3UI5 A;  1LG2 A;  1FKR A;  4UDM A;  5HTG A;  1FKB A;  3ARY A;  1LL7 A;  1NWR A;  2DT1 A;  3I6C A;  1ROT A;  2UZ5 A;  3WD1 A;  2L2S A;  2OFN A;  4MNL A;  4Z2K A;  2MPH A;  4Z2J A;  1HKK A;  5HWC A;  3UI6 A;  4PTM A;  3ODK A;  4QZV B;  3UI4 A;  2PV1 A;  1ZU8 A;  4G2P A;  4MGV A;  1BL4 A;  1NWT A;  4NZC A;  3KAD A;  4WKA A;  2IUZ A;  3EY6 A;  1OGB A;  1HJV A;  3PRB A;  4LAV A;  1J4R A;  3O5F A;  2P4V A;  2LKN A;  1OWQ A;  3PRA A;  1P5Q A;  2F23 A;  4TW8 A;  3JYJ A;  4HBE A;  1N1A A;  4XAK A;  1GUV A;  1TFV A;  1FKL A;  2VN1 A;  3KZ7 A;  4DH0 A;  4DRI A;  4KQZ A;  2XP5 A;  5HW8 A;  4FN2 A;  2N87 A;  4LAX A;  3WD3 A;  1JNE A;  2ZQU A;  3WD4 A;  5DF0 A;  1YAT A;  2KR7 A;  4ZPT R;  1J6Y A;  4DRO A;  5HKG A;  4W9O A;  3UQB A;  1O6I A;  1W9U A;  3ALG A;  4ODN A;  4QT2 A;  4DWS A;  4ZPW R;  1HJX A;  3AQU A;  3RFW A;  1ZK6 A;  2AOS A;  4W9Q A;  1ZBW A;  2AWG A;  2DG9 A;  2A3E A;  2XP4 A;  2O92 A;  4JFM A;  4GGQ A;  3BXW A;  3UQI A;  1TCO C;  1WB0 A;  3O5Q A;  5J6E A;  3TC5 A;  1W1T A;  1ZBV A;  3KAH A;  5DIT A;  2XP7 A;  4P8V A;  4S3J A;  5GPG A;  4ODQ A;  1W9P A;  1E15 A;  2O9O A;  4ZPV R;  4ODK A;  3O5O A;  1JCH B;  1EDQ A;  4DRJ A;  3WH0 A;  1VF8 A;  1D6O A;  4Q22 A;  2A3B A;  4LAY A;  2FKE A;  3KCE A;  3WD2 A;  3TCZ A;  4ODO A;  4U84 A;  4WIW A;  3KAF A;  3LUO A;  1ZL1 A;  4DRK A;  5DIV A;  3RGC A;  2PPP A;  1D7I A;  3WQW A;  4DWS C;  3CHE A;  5B8I C;  1JNS A;  1FKS A;  3ARV A;  2EUL A;  4KR0 B;  1FKG A;  2DSV A;  2PI6 A;  2YBT A;  1H0I A;  4S3K A;  5GQB A;  5HT1 A;  3RME A;  1E44 A;  1NH6 A;  1FKT A;  4IQ2 A;  2LJ4 A;  2RSE A;  2MNT A;  3BMB A;  2PPN A;  3FXY A;  4HBO A;  3RM4 A;  1E6N A;  1L1P A;  3UQA A;  5DO2 A;  4Z2G A;  3CGN A;  4IQC A;  3FY1 A;  2VCD A;  2B5U B;  2A3A A;  2F21 A;  5HWB A;  2M08 A;  1D2K A;  1KT1 A;  5DIU A;  2K8I A;  1CTN A;  3ARO A;  3O5I A;  3TDB A;  3O5L A;  2PBC A;  1OGG A;  1FFQ A;  2WLY A;  4R5E A;  2RQS A;  4MAV A;  1ROU A;  4JFJ A;  4QIB A;  2ZR5 A;  4ML4 A;  3ALF A;  2XP3 A;  4Z2L A;  2FDM A;  1ITX A;  3G6M A;  2DSZ A;  3KAB A;  3PA7 A;  2RUC A;  3B9E A;  3H9R B;  4DT4 A;  3VAW A;  1FKI A;  3WQV A;  3AS2 A;  4ODR A;  3KAI A;  4U85 A;  4MNK A;  4ZS6 A;  3WKZ A;  1JNT A;  2WLZ A;  1J4I A;  3ARW A;  1IX5 A;  1T11 A;  1JVW A;  3CHD A;  1D7J A;  1NMW A;  1Q1C A;  4MNM A;  2XP6 A;  1B6C A;  2DT0 A;  5HBF A;  1PBK A;  2FAP A;  4GIV A;  4TNS A;  1NMV A;  3O5D A;  3IHZ A;  1EIB A;  3O5K A;  1E6R A;  1EYM A;  1BKF A;  4N19 A;  2DSU A;  3ARS A;  3KAC A;  3NI6 A;  4L72 B;  1Q6I A;  1HKM A;  3ARZ A;  3IK8 A;  2OLH A;  4DRM A;  1W1Y A;  2DG3 A;  4Z2I A;  4NNR A;  1EHN A;  3B7X A;  2KI3 A;  4BF8 A;  5D75 A;  2ITK A;  4IT6 A;  4JYS A;  2M1I A;  2MLY A;  3W4R A;  3NRK A;  3O5G A;  1UR8 A;  2QF8 A;  4HAR A;  3WL0 A;  4MPK A;  3IKD A;  1NWS A;  4O2T A;  1E6P A;  1ZB5 A;  2ZQT A;  4QT3 A;  1FKJ A;  2LPV A;  1HKI A;  5JH8 A;  2Y78 A;  1UR9 A;  2JZV A;  2M2A A;  1ZBK A;  1YW5 A;  2XPB A;  3OOB A;  4ODM A;  3FAP A;  3O5M A;  1HKJ A;  4DRN A;  4WKH A;  3RM8 A;  1HXV A;  1F40 A;  1LQ0 A;  4WK9 A;  2F4E A;  1HJW A;  3AS3 A;  2D9F A;  1Q6H A;  1LL4 A;  1R9H A;  1PIN A;  3GTY X;  4DWS D;  1JND A;  3ARU A;  3KAG A;  4LGX A;  2ZR4 A;  2Q5A A;  1LJY A;  2DG4 A;  1GOI A;  4DWS B;  3QOK A;  1Q6U A;  1U79 A;  4LAW A;  3ART A;  3CH9 A;  1FKK A;  3ARQ A;  4P8W A;  4P8U A;  2XP9 A;  3B9D A;  1H0G A;  1WAW A;  3O5E A;  4URI A;  4FAP A;  4WKF A;  4Z2H A;  2DT3 A;  4JFL A;  4TW7 A;  3IKG A;  2PN0 A;  1Y0O A;  2YBU A;  4MSP A; 
#chains in the Genus database with same CATH homology
 4IPX A;  1XRV A;  3WIJ A;  3CHF A;  1W1V A;  2XP8 A;  2KO7 A;  4TW6 A;  3CGM A;  1QZ2 A;  2RUR A;  2ZR6 A;  1QPL A;  2PPO A;  1FKD A;  1XHG A;  3O5R A;  2PV3 A;  5BXJ A;  4JFI A;  3O5P A;  1RD6 A;  4DRQ A;  1A7X A;  1KFW A;  2F2D A;  3B9A A;  2PV2 A;  1K9T A;  4ODL A;  4L3N A;  2ZQS A;  4MTV A;  3WL1 A;  2LGO A;  5I98 A;  2B31 A;  4R0X A;  1FKH A;  4AY1 A;  4C02 B;  4IT4 A;  4NSB A;  1W26 A;  3GPK A;  2MLZ A;  1QPF A;  2MF9 A;  4TYO A;  5HW6 A;  1FAP A;  3WD0 A;  4J4N A;  2DSW A;  4MNJ A;  1FFR A;  3CHC A;  4JFK A;  3ARR A;  3AS0 A;  4W5U A;  1E9L A;  3ARX A;  1X6N A;  4DZ2 A;  1E6Z A;  1M5Y A;  4ITZ A;  1KT0 A;  2RUD A;  3B8S A;  4DIP A;  5DEZ A;  3MDY B;  1J4H A;  1D7H A;  4WJX A;  4DZ3 A;  3NTP A;  1EQ3 A;  1WNO A;  3UF8 A;  4ODP A;  1NWU A;  2WK2 A;  2WM0 A;  3JYM A;  5GPR A;  5HUA A;  2RUQ A;  2G8Z A;  3PR9 A;  4J4O A;  1F8A B;  1FD9 A;  3OA5 A;  3O5J A;  3RM9 A;  3PRD A;  2KE0 A;  4Q7N A;  4TX0 A;  4DRH A;  1FKF A;  5HW7 A;  1NSG A;  2MLX A;  1C9H A;  1W9V A;  2KGJ A;  4U86 A;  2XPA A;  2ZQV A;  1ZBC A;  2KFW A;  4P8X A;  1FJD A;  1W1P A;  4DRP A;  3ARP A;  3AS1 A;  4W9P A;  2IF4 A;  3JXV A;  1X6L A;  2G41 A;  3G6L A;  2A3C A;  4G50 A;  1SYT A;  2ESC A;  3CZ8 A;  2DT2 A;  1LG1 A;  2DPE A;  1SR0 A;  1GPF A;  1LL6 A;  1ZCN A;  3UI5 A;  1LG2 A;  1FKR A;  5HTG A;  1FKB A;  3ARY A;  1LL7 A;  1NWR A;  2DT1 A;  3I6C A;  1ROT A;  2UZ5 A;  3WD1 A;  2L2S A;  2OFN A;  4MNL A;  4Z2K A;  2MPH A;  4Z2J A;  1HKK A;  5HWC A;  3UI6 A;  4PTM A;  3ODK A;  4QZV B;  3UI4 A;  2PV1 A;  1ZU8 A;  4G2P A;  4MGV A;  1BL4 A;  1NWT A;  4NZC A;  3KAD A;  4WKA A;  2IUZ A;  3EY6 A;  1OGB A;  1HJV A;  3PRB A;  4LAV A;  1J4R A;  3O5F A;  2LKN A;  1OWQ A;  3PRA A;  1P5Q A;  4TW8 A;  3JYJ A;  4HBE A;  1N1A A;  4XAK A;  1GUV A;  1TFV A;  1FKL A;  2VN1 A;  3KZ7 A;  4DH0 A;  4DRI A;  4KQZ A;  2XP5 A;  5HW8 A;  4FN2 A;  2N87 A;  4LAX A;  3WD3 A;  1JNE A;  2ZQU A;  3WD4 A;  5DF0 A;  1YAT A;  2KR7 A;  4ZPT R;  1J6Y A;  4DRO A;  5HKG A;  4W9O A;  3UQB A;  1O6I A;  1W9U A;  3ALG A;  4ODN A;  4QT2 A;  4DWS A;  4ZPW R;  1HJX A;  3AQU A;  3RFW A;  1ZK6 A;  2AOS A;  4W9Q A;  1ZBW A;  2AWG A;  2DG9 A;  2A3E A;  2XP4 A;  2O92 A;  4JFM A;  4GGQ A;  3BXW A;  3UQI A;  1TCO C;  1WB0 A;  3O5Q A;  5J6E A;  3TC5 A;  1W1T A;  1ZBV A;  3KAH A;  5DIT A;  2XP7 A;  4P8V A;  4S3J A;  5GPG A;  4ODQ A;  1W9P A;  1E15 A;  2O9O A;  4ZPV R;  4ODK A;  3O5O A;  1EDQ A;  4DRJ A;  3WH0 A;  1VF8 A;  1D6O A;  4Q22 A;  2A3B A;  4LAY A;  2FKE A;  3KCE A;  3WD2 A;  3TCZ A;  4ODO A;  4U84 A;  4WIW A;  3KAF A;  3LUO A;  1ZL1 A;  4DRK A;  5DIV A;  3RGC A;  2PPP A;  1D7I A;  3WQW A;  4DWS C;  3CHE A;  5B8I C;  1JNS A;  1FKS A;  3ARV A;  4KR0 B;  1FKG A;  2DSV A;  2PI6 A;  2YBT A;  1H0I A;  4S3K A;  5GQB A;  5HT1 A;  3RME A;  1NH6 A;  1FKT A;  4IQ2 A;  2LJ4 A;  2RSE A;  2MNT A;  3FXY A;  2PPN A;  4HBO A;  3RM4 A;  1E6N A;  1L1P A;  3UQA A;  5DO2 A;  4Z2G A;  3CGN A;  4IQC A;  3FY1 A;  2VCD A;  2A3A A;  2F21 A;  5HWB A;  2M08 A;  1D2K A;  1KT1 A;  5DIU A;  2K8I A;  1CTN A;  3ARO A;  3O5I A;  3TDB A;  3O5L A;  2PBC A;  1OGG A;  1FFQ A;  2WLY A;  4R5E A;  2RQS A;  4MAV A;  1ROU A;  4JFJ A;  4QIB A;  2ZR5 A;  4ML4 A;  3ALF A;  2XP3 A;  4Z2L A;  2FDM A;  1ITX A;  3G6M A;  2DSZ A;  3KAB A;  3PA7 A;  2RUC A;  3B9E A;  3H9R B;  4DT4 A;  3VAW A;  1FKI A;  3WQV A;  3AS2 A;  4ODR A;  3KAI A;  4U85 A;  4MNK A;  4ZS6 A;  3WKZ A;  1JNT A;  2WLZ A;  1J4I A;  3ARW A;  1IX5 A;  1T11 A;  1JVW A;  3CHD A;  1D7J A;  1NMW A;  1Q1C A;  4MNM A;  2XP6 A;  1B6C A;  2DT0 A;  5HBF A;  1PBK A;  2FAP A;  4GIV A;  4TNS A;  1NMV A;  3O5D A;  3IHZ A;  1EIB A;  3O5K A;  1E6R A;  1EYM A;  1BKF A;  4N19 A;  2DSU A;  3ARS A;  3KAC A;  3NI6 A;  4L72 B;  1Q6I A;  1HKM A;  3ARZ A;  3IK8 A;  2OLH A;  4DRM A;  1W1Y A;  2DG3 A;  4Z2I A;  4NNR A;  1EHN A;  3B7X A;  2KI3 A;  4BF8 A;  5D75 A;  2ITK A;  4IT6 A;  4JYS A;  2M1I A;  2MLY A;  3W4R A;  3NRK A;  3O5G A;  1UR8 A;  2QF8 A;  4HAR A;  3WL0 A;  4MPK A;  3IKD A;  1NWS A;  4O2T A;  1E6P A;  1ZB5 A;  2ZQT A;  4QT3 A;  1FKJ A;  2LPV A;  1HKI A;  5JH8 A;  2Y78 A;  1UR9 A;  2JZV A;  2M2A A;  1ZBK A;  1YW5 A;  2XPB A;  3OOB A;  4ODM A;  3FAP A;  3O5M A;  1HKJ A;  4DRN A;  4WKH A;  3RM8 A;  1HXV A;  1F40 A;  1LQ0 A;  4WK9 A;  2F4E A;  1HJW A;  3AS3 A;  2D9F A;  1Q6H A;  1LL4 A;  1R9H A;  1PIN A;  4DWS D;  1JND A;  3ARU A;  3KAG A;  4LGX A;  2ZR4 A;  2Q5A A;  1LJY A;  2DG4 A;  1GOI A;  4DWS B;  3QOK A;  1Q6U A;  1U79 A;  4LAW A;  3ART A;  3CH9 A;  1FKK A;  3ARQ A;  4P8W A;  4P8U A;  2XP9 A;  3B9D A;  1H0G A;  1WAW A;  3O5E A;  4URI A;  4FAP A;  4WKF A;  4Z2H A;  2DT3 A;  4JFL A;  4TW7 A;  3IKG A;  1Y0O A;  2YBU A;  4MSP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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