4E2KA

The structure of the s. aureus dnag rna polymerase domain
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
321
structure length
319
Chain Sequence
SNADDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords DNA primase
publication title Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 116
structure length 319
sequence length 321
ec nomenclature ec 2.7.7.-:
pdb deposition date 2012-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08275 Toprim_N DNA primase catalytic core, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.50.20 Mainly Alpha Up-down Bundle Pheromone ER-1 Pheromone ER-1 4e2kA03
3.40.1360.10 Alpha Beta 3-Layer(aba) Sandwich Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 Dna Topoisomerase Vi A Subunit; Chain: A, domain 2 4e2kA02
3.90.980.10 Alpha Beta Alpha-Beta Complex DNA primase DNAg catalytic core, N-terminal domain DNA primase, catalytic core, N-terminal domain 4e2kA01
1T6T1 4JCVA 3VDUA 2AU3A 4O6OA 4EE1A 1D3YA 4EDRA 2ZBKA 4EDVA 1DD9A 3VE5A 2Q2EA 1VDDA 4E2KA 3B39A 2V1CA 4EDKA 4O6PB 4EDTA 3VDPA 5GUJA 1DDEA 1EQNA 4EDGA
chains in the Genus database with same CATH superfamily
2KK2A 1T6T1 4JCVA 3VDUA 2AU3A 4O6OA 2KC6A 2LMKA 4EE1A 2NSVA 1D3YA 2FCJA 4EDRA 3KLSA 2ZBKA 4EDVA 1DD9A 3VE5A 3KXRA 2ERLA 2Q2EA 1VDDA 4E2KA 3B39A 2V1CA 1ERCA 4EDKA 3CU7A 4O6PB 4EDTA 2JMSA 3VDPA 5GUJA 2B39A 1DDEA 2I5RA 1EQNA 4EDGA 2NSWA
chains in the Genus database with same CATH topology
2KK2A 1T6T1 4JCVA 3VDUA 2AU3A 4O6OA 2KC6A 2LMKA 4EE1A 2NSVA 1D3YA 4EDRA 3KLSA 2ZBKA 4EDVA 1DD9A 3VE5A 3KXRA 2ERLA 2Q2EA 1VDDA 4E2KA 3B39A 2V1CA 1ERCA 4EDKA 3CU7A 4O6PB 4EDTA 2JMSA 3VDPA 5GUJA 2B39A 1DDEA 1EQNA 4EDGA 2NSWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T6T 1;  4JCV A;  3VDU A;  2AU3 A;  4O6O A;  4EE1 A;  1D3Y A;  4EDR A;  2ZBK A;  4EDV A;  1DD9 A;  3VE5 A;  2Q2E A;  1VDD A;  4E2K A;  3B39 A;  2V1C A;  4EDK A;  4O6P B;  4EDT A;  3VDP A;  5GUJ A;  1DDE A;  1EQN A;  4EDG A; 
#chains in the Genus database with same CATH topology
 2KK2 A;  1T6T 1;  4JCV A;  3VDU A;  2AU3 A;  4O6O A;  2KC6 A;  2LMK A;  4EE1 A;  2NSV A;  1D3Y A;  2FCJ A;  4EDR A;  3KLS A;  2ZBK A;  4EDV A;  1DD9 A;  3VE5 A;  3KXR A;  2ERL A;  2Q2E A;  1VDD A;  4E2K A;  3B39 A;  2V1C A;  1ERC A;  4EDK A;  3CU7 A;  4O6P B;  4EDT A;  2JMS A;  3VDP A;  5GUJ A;  2B39 A;  1DDE A;  2I5R A;  1EQN A;  4EDG A;  2NSW A; 
#chains in the Genus database with same CATH homology
 2KK2 A;  1T6T 1;  4JCV A;  3VDU A;  2AU3 A;  4O6O A;  2KC6 A;  2LMK A;  4EE1 A;  2NSV A;  1D3Y A;  4EDR A;  3KLS A;  2ZBK A;  4EDV A;  1DD9 A;  3VE5 A;  3KXR A;  2ERL A;  2Q2E A;  1VDD A;  4E2K A;  3B39 A;  2V1C A;  1ERC A;  4EDK A;  3CU7 A;  4O6P B;  4EDT A;  2JMS A;  3VDP A;  5GUJ A;  2B39 A;  1DDE A;  1EQN A;  4EDG A;  2NSW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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