4E44B

Crystal structure of the hmhf1/hmhf2 histone-fold tetramer
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
75
structure length
75
Chain Sequence
GSGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein
molecule keywords Centromere protein S
publication title Crystal Structures Reveal that FANCM remodels the MHF Tetramer in favor of binding Branched DNA
rcsb
source organism Homo sapiens
total genus 26
structure length 75
sequence length 75
chains with identical sequence D
ec nomenclature
pdb deposition date 2012-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4e44B02
3B0BC 4NE3B 4E44B 4DRBJ 4DRAE 4NE6B 4E45B 4NE5B
chains in the Genus database with same CATH superfamily
4E44B 4DRAE 1EFUB 1FB1A 2WSEK 4E45B 4R8QA 1WUQA 4DU6A 2LNZA 2WSEG 1N3TA 3VEJA 3B0BC 2P11A 4DRBJ 3BMBA 3LW5K 4JA3A 1A8RA 1EL6A 2O01G 3LW5G 4NE5B 1N3SA 1GTPA 1TFEA 2KR1A 2PN0A 2WSFK 4Q7JA 2WSFG 4NE6B 1IS7A 1A9CA 4QPMA 2LO0A 1FBXA 4NE3B 1WM9A 1IS8A 1WURA 5DMZA 1WPLA 2WSCK 1AIPC 1N3RA 2WSCG
chains in the Genus database with same CATH topology
4E44B 4DRAE 1EFUB 1FB1A 4E45B 4R8QA 1WUQA 4DU6A 2LNZA 1N3TA 3VEJA 3B0BC 2P11A 4DRBJ 3BMBA 4JA3A 1A8RA 1EL6A 4NE5B 1N3SA 1GTPA 1TFEA 2KR1A 2PN0A 4Q7JA 4NE6B 1IS7A 1A9CA 4QPMA 2LO0A 1FBXA 4NE3B 1WM9A 1IS8A 1WURA 5DMZA 1WPLA 1AIPC 1N3RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3B0B C;  4NE3 B;  4E44 B;  4DRB J;  4DRA E;  4NE6 B;  4E45 B;  4NE5 B; 
#chains in the Genus database with same CATH topology
 4E44 B;  4DRA E;  1EFU B;  1FB1 A;  2WSE K;  4E45 B;  4R8Q A;  1WUQ A;  4DU6 A;  2LNZ A;  2WSE G;  1N3T A;  3VEJ A;  3B0B C;  2P11 A;  4DRB J;  3BMB A;  3LW5 K;  4JA3 A;  1A8R A;  1EL6 A;  2O01 G;  3LW5 G;  4NE5 B;  1N3S A;  1GTP A;  1TFE A;  2KR1 A;  2PN0 A;  2WSF K;  4Q7J A;  2WSF G;  4NE6 B;  1IS7 A;  1A9C A;  4QPM A;  2LO0 A;  1FBX A;  4NE3 B;  1WM9 A;  1IS8 A;  1WUR A;  5DMZ A;  1WPL A;  2WSC K;  1AIP C;  1N3R A;  2WSC G; 
#chains in the Genus database with same CATH homology
 4E44 B;  4DRA E;  1EFU B;  1FB1 A;  4E45 B;  4R8Q A;  1WUQ A;  4DU6 A;  2LNZ A;  1N3T A;  3VEJ A;  3B0B C;  2P11 A;  4DRB J;  3BMB A;  4JA3 A;  1A8R A;  1EL6 A;  4NE5 B;  1N3S A;  1GTP A;  1TFE A;  2KR1 A;  2PN0 A;  4Q7J A;  4NE6 B;  1IS7 A;  1A9C A;  4QPM A;  2LO0 A;  1FBX A;  4NE3 B;  1WM9 A;  1IS8 A;  1WUR A;  5DMZ A;  1WPL A;  1AIP C;  1N3R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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