4E91A

Crystal structure of the n-terminal domain of hiv-1 capsid in complex with inhibitor bd3
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
146
structure length
131
Chain Sequence
PIVQVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVMREPRGSDIAGTTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein.
pubmed doi rcsb
molecule keywords Gag protein
molecule tags Structural protein/inhibitor
source organism Human immunodeficiency virus 1
total genus 48
structure length 131
sequence length 146
chains with identical sequence B
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2012-03-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.375.10 Mainly Alpha Orthogonal Bundle Human Immunodeficiency Virus Type 1 Capsid Protein Human Immunodeficiency Virus Type 1 Capsid Protein 4e91A00
4XFXA 4WYMA 1M9DC 4U0DA 4DGAC 2GONA 1M9EC 2JPRA 1AK4C 2X82A 1M9CC 2EIAA 5JPAA 2XGUA 2V4XA 1EM9A 1L6NA 2M8NA 4E91A 1M9FC 4XFYA 1M9YC 1P7NA 2WLVB 1E6JP 2M8PA 5HGOA 4U0CA 4PH0A 2M8LA 2XGYA 3BP9A 1GWPA 4XRQA 4J93A 3P05A 5HGMA 2PWOA 2PWMA 2XDEA 2PXRC 3MGEA 4U0FA 2Y4ZA 4B4NA 2X2DD 4U0BA 4HTWA 4PH3A 1M9XC 4INBA 1G03A 4XFZA 4LQWC 1EIAA 4PH2A 4XROA 1U7KA 2KGFA 4DGEC 4QNBA 2LF4A 5HGNA 1D1DA 4U0EA 5HGKA 2WLVA 4E92A 3NTEA 1QRJA 5HGLA 2X83A 1AFVA 3H4EA 4U0AA 2GOLB 2XGVA 3H47A 4NX4C
chains in the Genus database with same CATH superfamily
4XFXA 4WYMA 1M9DC 4U0DA 4DGAC 2GONA 1M9EC 2JPRA 1AK4C 2X82A 1M9CC 2EIAA 5JPAA 2XGUA 2V4XA 1EM9A 1L6NA 2M8NA 4E91A 1M9FC 4XFYA 1M9YC 1P7NA 2WLVB 1E6JP 2M8PA 5HGOA 4U0CA 4PH0A 2M8LA 2XGYA 3BP9A 1GWPA 4XRQA 4J93A 3P05A 5HGMA 2PWOA 2PWMA 2XDEA 2PXRC 3MGEA 4U0FA 2Y4ZA 4B4NA 2X2DD 4U0BA 4HTWA 4PH3A 1M9XC 4INBA 1G03A 4XFZA 4LQWC 1EIAA 4PH2A 4XROA 1U7KA 2KGFA 4DGEC 4QNBA 2LF4A 5HGNA 1D1DA 4U0EA 5HGKA 2WLVA 4E92A 3NTEA 1QRJA 5HGLA 2X83A 1AFVA 3H4EA 4U0AA 2GOLB 2XGVA 3H47A 4NX4C
chains in the Genus database with same CATH topology
4XFXA 4WYMA 1M9DC 4U0DA 4DGAC 2GONA 1M9EC 2JPRA 1AK4C 2X82A 1M9CC 2EIAA 5JPAA 2XGUA 2V4XA 1EM9A 1L6NA 2M8NA 4E91A 1M9FC 4XFYA 1M9YC 1P7NA 2WLVB 1E6JP 2M8PA 5HGOA 4U0CA 4PH0A 2M8LA 2XGYA 3BP9A 1GWPA 4XRQA 4J93A 3P05A 5HGMA 2PWOA 2PWMA 2XDEA 2PXRC 3MGEA 4U0FA 2Y4ZA 4B4NA 2X2DD 4U0BA 4HTWA 4PH3A 1M9XC 4INBA 1G03A 4XFZA 4LQWC 1EIAA 4PH2A 4XROA 1U7KA 2KGFA 4DGEC 4QNBA 2LF4A 5HGNA 1D1DA 4U0EA 5HGKA 2WLVA 4E92A 3NTEA 1QRJA 5HGLA 2X83A 1AFVA 3H4EA 4U0AA 2GOLB 2XGVA 3H47A 4NX4C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XFX A;  4WYM A;  1M9D C;  4U0D A;  4DGA C;  2GON A;  1M9E C;  2JPR A;  1AK4 C;  2X82 A;  1M9C C;  2EIA A;  5JPA A;  2XGU A;  2V4X A;  1EM9 A;  1L6N A;  2M8N A;  4E91 A;  1M9F C;  4XFY A;  1M9Y C;  1P7N A;  2WLV B;  1E6J P;  2M8P A;  5HGO A;  4U0C A;  4PH0 A;  2M8L A;  2XGY A;  3BP9 A;  1GWP A;  4XRQ A;  4J93 A;  3P05 A;  5HGM A;  2PWO A;  2PWM A;  2XDE A;  2PXR C;  3MGE A;  4U0F A;  2Y4Z A;  4B4N A;  2X2D D;  4U0B A;  4HTW A;  4PH3 A;  1M9X C;  4INB A;  1G03 A;  4XFZ A;  4LQW C;  1EIA A;  4PH2 A;  4XRO A;  1U7K A;  2KGF A;  4DGE C;  4QNB A;  2LF4 A;  5HGN A;  1D1D A;  4U0E A;  5HGK A;  2WLV A;  4E92 A;  3NTE A;  1QRJ A;  5HGL A;  2X83 A;  1AFV A;  3H4E A;  4U0A A;  2GOL B;  2XGV A;  3H47 A;  4NX4 C; 
#chains in the Genus database with same CATH topology
 4XFX A;  4WYM A;  1M9D C;  4U0D A;  4DGA C;  2GON A;  1M9E C;  2JPR A;  1AK4 C;  2X82 A;  1M9C C;  2EIA A;  5JPA A;  2XGU A;  2V4X A;  1EM9 A;  1L6N A;  2M8N A;  4E91 A;  1M9F C;  4XFY A;  1M9Y C;  1P7N A;  2WLV B;  1E6J P;  2M8P A;  5HGO A;  4U0C A;  4PH0 A;  2M8L A;  2XGY A;  3BP9 A;  1GWP A;  4XRQ A;  4J93 A;  3P05 A;  5HGM A;  2PWO A;  2PWM A;  2XDE A;  2PXR C;  3MGE A;  4U0F A;  2Y4Z A;  4B4N A;  2X2D D;  4U0B A;  4HTW A;  4PH3 A;  1M9X C;  4INB A;  1G03 A;  4XFZ A;  4LQW C;  1EIA A;  4PH2 A;  4XRO A;  1U7K A;  2KGF A;  4DGE C;  4QNB A;  2LF4 A;  5HGN A;  1D1D A;  4U0E A;  5HGK A;  2WLV A;  4E92 A;  3NTE A;  1QRJ A;  5HGL A;  2X83 A;  1AFV A;  3H4E A;  4U0A A;  2GOL B;  2XGV A;  3H47 A;  4NX4 C; 
#chains in the Genus database with same CATH homology
 4XFX A;  4WYM A;  1M9D C;  4U0D A;  4DGA C;  2GON A;  1M9E C;  2JPR A;  1AK4 C;  2X82 A;  1M9C C;  2EIA A;  5JPA A;  2XGU A;  2V4X A;  1EM9 A;  1L6N A;  2M8N A;  4E91 A;  1M9F C;  4XFY A;  1M9Y C;  1P7N A;  2WLV B;  1E6J P;  2M8P A;  5HGO A;  4U0C A;  4PH0 A;  2M8L A;  2XGY A;  3BP9 A;  1GWP A;  4XRQ A;  4J93 A;  3P05 A;  5HGM A;  2PWO A;  2PWM A;  2XDE A;  2PXR C;  3MGE A;  4U0F A;  2Y4Z A;  4B4N A;  2X2D D;  4U0B A;  4HTW A;  4PH3 A;  1M9X C;  4INB A;  1G03 A;  4XFZ A;  4LQW C;  1EIA A;  4PH2 A;  4XRO A;  1U7K A;  2KGF A;  4DGE C;  4QNB A;  2LF4 A;  5HGN A;  1D1D A;  4U0E A;  5HGK A;  2WLV A;  4E92 A;  3NTE A;  1QRJ A;  5HGL A;  2X83 A;  1AFV A;  3H4E A;  4U0A A;  2GOL B;  2XGV A;  3H47 A;  4NX4 C; 
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