4EAFA

Thymidine phosphorylase from e.coli
Total Genus 154
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
154
sequence length
440
structure length
440
Chain Sequence
b'LFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENNWQEAAKAVKAAIKLADKAPESTPTVYRRISE'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Thymidine phosphorylase
publication title Thymidine phosphorylase from E.coli
rcsb
source organism Escherichia coli
molecule tags Transferase
total genus 154
structure length 440
sequence length 440
ec nomenclature ec 2.4.2.4: Thymidine phosphorylase.
pdb deposition date 2012-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00591 Glycos_transf_3 Glycosyl transferase family, a/b domain
A PF02885 Glycos_trans_3N Glycosyl transferase family, helical bundle domain
A PF07831 PYNP_C Pyrimidine nucleoside phosphorylase C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.970.10 Mainly Alpha Up-down Bundle Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 4eafA01
3.40.1030.10 Alpha Beta 3-Layer(aba) Sandwich Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 4eafA02
3.90.1170.30 Alpha Beta Alpha-Beta Complex Aldehyde Oxidoreductase; domain 3 Pyrimidine nucleoside phosphorylase-like, C-terminal domain 4eafA03
1ZXYA 5BO2A 4X5CA 4GA6A 4OWSA 1KHDA 1V8GA 4MUOA 4ZOKA 4OWNA 4X5BA 5BNEA 4YYYA 1O17A 2DSJA 1UOUA 1GXBA 1KGZA 4N8QA 2ELCA 4GA5A 4X59A 4IJ1A 1OTPA 5C2LA 4LHMA 4ZOJA 4N5VA 2GVQA 2TPTA 5EP8A 4OWVA 4HKMA 4OWOA 4OWUA 3QSAA 2BPQA 4ZOFA 1AZYA 1VQUA 4YEKA 4X5AA 5BO3A 4YI7A 4OWMA 2WK5A 5C7SA 4GTNA 3R88A 5BYTA 3QQSA 3R6CA 5EY3A 4GIUA 5C1RA 4EAFA 3GBRA 2J0FA 4X58A 4EADA 2WK6A 4XR5A 1ZVWA 4X46A 1BRWA 3QS8A 4M0RA 4ZTVA 4N93A 3H5QA 4GA4A 4GKMA 3UU1A 4OWQA 3QR9A 4X5DA 1ZYKA 4X5EA 3TWPA
chains in the Genus database with same CATH superfamily
2PA2A 1ZXYA 4WCEJ 5BO2A 4I9AA 5AN9F 1N8RJ 4GA6A 4X5CA 4OWSA 4WFAJ 3CXCH 1KHDA 1YJWH 1KC8J 1V8GA 1FIQC 1NVJA 4IO9J 4MUOA 2ZJPJ 4ZOKA 4OWNA 4X5BA 5BNEA 1Y69K 3RPFA 4YYYA 5MLCO 3AMZA 1O17A 2JBMA 3B9JC 2DSJA 1UOUA 3NVVC 1VQNH 5HL7J 4KWWA 2B7NA 3G71H 3CCVH 1QVFH 1GXBA 1N62B 1JJ2H 1KGZA 4US9A 4N8QA 1QPQA 2ELCA 5DM7J 1FO4A 4GA5A 5DM6J 3C2OA 2ZJQJ 3CCEH 1VQOH 5JVHJ 3C2RA 3FC4A 5GAHN 4WFBJ 1Q82J 4X59A 1SIJA 2Q5WE 3I55H 1Q81J 3TQVA 4IOAJ 4IJ1A 1RM6A 3CF5J 1Q7YJ 5AYXA 3SR6C 3WO1A 1OTPA 4C7ZA 5C2LA 4LHMA 3CCJH 4ZOJA 5HULA 4C80A 1RF8B 1VQ9H 1K8AJ 1YTEA 4N5VA 1YI2H 2GVQA 2TPTA 5EP8A 3ETRC 3G6EH 4OWVA 4HKMA 2ZJRJ 4OWOA 3CD6H 3OW2H 2B7QA 3EUB4 1KQSH 4C7YA 5HUOA 3L0GA 3AN1A 3CCSH 1VQLH 4OWUA 3DLLJ 1N60B 3FAHA 5AYYA 1S72H 1VQMH 1VQ6H 3QSAA 1QVGH 2QA4H 1K9MJ 3BIIE 3NVYC 2BPQA 2B7PA 5GADN 1NJIJ 1NVIE 4UY8M 3CCQH 2OTJH 4ZOFA 1AZYA 1VQUA 1VQPH 1N63B 1YJNH 4U67J 4YEKA 4X5AA 1X1OA 1VQKH 5BO3A 1YTDA 3PIPJ 1YHQH 4YI7A 3WNZA 4OWMA 2QEXH 1M90J 1FMAE 1FFVB 3CC2H 2WK5A 3I56H 1W2BH 1JROB 5C7SA 3L4PA 5H1SO 1VQ5H 1M1KJ 3CPWH 1QPNA 2E3TA 1QAPA 2W3RB 3C2EA 3PAJA 3VMMA 3G4SH 4GTNA 1YIJH 1YJ9H 1K73J 3CMEH 1N5XA 3R88A 5BYTA 3QQSA 3CCLH 3R6CA 5EY3A 1WYGA 3C2VA 1SB3A 3AM9A 4GIUA 1YTKA 5C1RA 1KD1J 4KWVA 1JRPB 3CMAH 4EAFA 2QIEA 2OTLH 3GBRA 4WFNJ 2W55B 5GAGN 2J0FA 4X58A 3NS1C 4EADA 4ZOHA 2WK6A 5GAEN 3CC4H 3WO0A 4XR5A 1RRZA 4USAA 1VQ4H 1ZVWA 4X46A 2W54B 1O4UA 5AYZA 1N61B 1VQ8H 1BRWA 3C2FA 1YITH 3QS8A 4M0RA 4ZTVA 1Q86J 2I1OA 1VLBA 4F3FC 2OMDA 4N93A 3H5QA 1FM0E 4WF9J 4GA4A 2WP4A 4GKMA 5HUPA 3UU1A 4US8A 1V97A 4OWQA 2I14A 1N5WB 1QPRA 4AP8A 2W3SB 5JVGJ 3QR9A 1DGJA 1ZXIB 3CC7H 1VQ7H 5MPOC 4X5DA 3CCRH 3GNNA 3NRZC 4IOCJ 1ZYKA 4X5EA 3NVWC 3NVZC 3TWPA 3CCMH 1VDVA 3CCUH 3PIOJ 1FFUB 1WKIA 1QPOA 3J7ZM
chains in the Genus database with same CATH topology
1ZXYA 5BO2A 4X5CA 4GA6A 4OWSA 1KHDA 1V8GA 4MUOA 4ZOKA 4OWNA 4X5BA 5BNEA 4YYYA 1O17A 2DSJA 1UOUA 1GXBA 1KGZA 4N8QA 2ELCA 4GA5A 4X59A 4IJ1A 1OTPA 5C2LA 4LHMA 4ZOJA 4N5VA 2GVQA 2TPTA 5EP8A 4OWVA 4HKMA 4OWOA 4OWUA 3QSAA 2BPQA 4ZOFA 1AZYA 1VQUA 4YEKA 4X5AA 5BO3A 4YI7A 4OWMA 2WK5A 5C7SA 4GTNA 3R88A 5BYTA 3QQSA 3R6CA 5EY3A 4GIUA 5C1RA 4EAFA 3GBRA 2J0FA 4X58A 4EADA 2WK6A 4XR5A 1ZVWA 4X46A 1BRWA 3QS8A 4M0RA 4ZTVA 4N93A 3H5QA 4GA4A 4GKMA 3UU1A 4OWQA 3QR9A 4X5DA 1ZYKA 4X5EA 3TWPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZXY A;  5BO2 A;  4X5C A;  4GA6 A;  4OWS A;  1KHD A;  1V8G A;  4MUO A;  4ZOK A;  4OWN A;  4X5B A;  5BNE A;  4YYY A;  1O17 A;  2DSJ A;  1UOU A;  1GXB A;  1KGZ A;  4N8Q A;  2ELC A;  4GA5 A;  4X59 A;  4IJ1 A;  1OTP A;  5C2L A;  4LHM A;  4ZOJ A;  4N5V A;  2GVQ A;  2TPT A;  5EP8 A;  4OWV A;  4HKM A;  4OWO A;  4OWU A;  3QSA A;  2BPQ A;  4ZOF A;  1AZY A;  1VQU A;  4YEK A;  4X5A A;  5BO3 A;  4YI7 A;  4OWM A;  2WK5 A;  5C7S A;  4GTN A;  3R88 A;  5BYT A;  3QQS A;  3R6C A;  5EY3 A;  4GIU A;  5C1R A;  4EAF A;  3GBR A;  2J0F A;  4X58 A;  4EAD A;  2WK6 A;  4XR5 A;  1ZVW A;  4X46 A;  1BRW A;  3QS8 A;  4M0R A;  4ZTV A;  4N93 A;  3H5Q A;  4GA4 A;  4GKM A;  3UU1 A;  4OWQ A;  3QR9 A;  4X5D A;  1ZYK A;  4X5E A;  3TWP A; 
#chains in the Genus database with same CATH topology
 2PA2 A;  1ZXY A;  4WCE J;  5BO2 A;  4I9A A;  5AN9 F;  1N8R J;  4GA6 A;  4X5C A;  4OWS A;  4WFA J;  3CXC H;  1KHD A;  1YJW H;  1KC8 J;  1V8G A;  1FIQ C;  1NVJ A;  4IO9 J;  4MUO A;  2ZJP J;  4ZOK A;  4OWN A;  4X5B A;  5BNE A;  1Y69 K;  3RPF A;  4YYY A;  5MLC O;  3AMZ A;  1O17 A;  2JBM A;  3B9J C;  2DSJ A;  1UOU A;  3NVV C;  1VQN H;  5HL7 J;  4KWW A;  2B7N A;  3G71 H;  3CCV H;  1QVF H;  1GXB A;  1N62 B;  1JJ2 H;  1KGZ A;  4US9 A;  4N8Q A;  1QPQ A;  2ELC A;  5DM7 J;  1FO4 A;  4GA5 A;  5DM6 J;  3C2O A;  2ZJQ J;  3CCE H;  1VQO H;  5JVH J;  3C2R A;  3FC4 A;  5GAH N;  4WFB J;  1Q82 J;  4X59 A;  1SIJ A;  2Q5W E;  3I55 H;  1Q81 J;  3TQV A;  4IOA J;  4IJ1 A;  1RM6 A;  3CF5 J;  1Q7Y J;  5AYX A;  3SR6 C;  3WO1 A;  1OTP A;  4C7Z A;  5C2L A;  4LHM A;  3CCJ H;  4ZOJ A;  5HUL A;  4C80 A;  1RF8 B;  1VQ9 H;  1K8A J;  1YTE A;  4N5V A;  1YI2 H;  2GVQ A;  2TPT A;  5EP8 A;  3ETR C;  3G6E H;  4OWV A;  4HKM A;  2ZJR J;  4OWO A;  3CD6 H;  3OW2 H;  2B7Q A;  3EUB 4;  1KQS H;  4C7Y A;  5HUO A;  3L0G A;  3AN1 A;  3CCS H;  1VQL H;  4OWU A;  3DLL J;  1N60 B;  3FAH A;  5AYY A;  1S72 H;  1VQM H;  1VQ6 H;  3QSA A;  1QVG H;  2QA4 H;  1K9M J;  3BII E;  3NVY C;  2BPQ A;  2B7P A;  5GAD N;  1NJI J;  1NVI E;  4UY8 M;  3CCQ H;  2OTJ H;  4ZOF A;  1AZY A;  1VQU A;  1VQP H;  1N63 B;  1YJN H;  4U67 J;  4YEK A;  4X5A A;  1X1O A;  1VQK H;  5BO3 A;  1YTD A;  3PIP J;  1YHQ H;  4YI7 A;  3WNZ A;  4OWM A;  2QEX H;  1M90 J;  1FMA E;  1FFV B;  3CC2 H;  2WK5 A;  3I56 H;  1W2B H;  1JRO B;  5C7S A;  3L4P A;  5H1S O;  1VQ5 H;  1M1K J;  3CPW H;  1QPN A;  2E3T A;  1QAP A;  2W3R B;  3C2E A;  3PAJ A;  3VMM A;  3G4S H;  4GTN A;  1YIJ H;  1YJ9 H;  1K73 J;  3CME H;  1N5X A;  3R88 A;  5BYT A;  3QQS A;  3CCL H;  3R6C A;  5EY3 A;  1WYG A;  3C2V A;  1SB3 A;  3AM9 A;  4GIU A;  1YTK A;  5C1R A;  1KD1 J;  4KWV A;  1JRP B;  3CMA H;  4EAF A;  2QIE A;  2OTL H;  3GBR A;  4WFN J;  2W55 B;  5GAG N;  2J0F A;  4X58 A;  3NS1 C;  4EAD A;  4ZOH A;  2WK6 A;  5GAE N;  3CC4 H;  3WO0 A;  4XR5 A;  1RRZ A;  4USA A;  1VQ4 H;  1ZVW A;  4X46 A;  2W54 B;  1O4U A;  5AYZ A;  1N61 B;  1VQ8 H;  1BRW A;  3C2F A;  1YIT H;  3QS8 A;  4M0R A;  4ZTV A;  1Q86 J;  2I1O A;  1VLB A;  4F3F C;  2OMD A;  4N93 A;  3H5Q A;  1FM0 E;  4WF9 J;  4GA4 A;  2WP4 A;  4GKM A;  5HUP A;  3UU1 A;  4US8 A;  1V97 A;  4OWQ A;  2I14 A;  1N5W B;  1QPR A;  4AP8 A;  2W3S B;  5JVG J;  3QR9 A;  1DGJ A;  1ZXI B;  3CC7 H;  1VQ7 H;  5MPO C;  4X5D A;  3CCR H;  3GNN A;  3NRZ C;  4IOC J;  1ZYK A;  4X5E A;  3NVW C;  3NVZ C;  3TWP A;  3CCM H;  1VDV A;  3CCU H;  3PIO J;  1FFU B;  1WKI A;  1QPO A;  3J7Z M; 
#chains in the Genus database with same CATH homology
 1ZXY A;  5BO2 A;  4X5C A;  4GA6 A;  4OWS A;  1KHD A;  1V8G A;  4MUO A;  4ZOK A;  4OWN A;  4X5B A;  5BNE A;  4YYY A;  1O17 A;  2DSJ A;  1UOU A;  1GXB A;  1KGZ A;  4N8Q A;  2ELC A;  4GA5 A;  4X59 A;  4IJ1 A;  1OTP A;  5C2L A;  4LHM A;  4ZOJ A;  4N5V A;  2GVQ A;  2TPT A;  5EP8 A;  4OWV A;  4HKM A;  4OWO A;  4OWU A;  3QSA A;  2BPQ A;  4ZOF A;  1AZY A;  1VQU A;  4YEK A;  4X5A A;  5BO3 A;  4YI7 A;  4OWM A;  2WK5 A;  5C7S A;  4GTN A;  3R88 A;  5BYT A;  3QQS A;  3R6C A;  5EY3 A;  4GIU A;  5C1R A;  4EAF A;  3GBR A;  2J0F A;  4X58 A;  4EAD A;  2WK6 A;  4XR5 A;  1ZVW A;  4X46 A;  1BRW A;  3QS8 A;  4M0R A;  4ZTV A;  4N93 A;  3H5Q A;  4GA4 A;  4GKM A;  3UU1 A;  4OWQ A;  3QR9 A;  4X5D A;  1ZYK A;  4X5E A;  3TWP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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