4EFCA

Crystal structure of adenylosuccinate lyase from trypanosoma brucei, tb427tmp.160.5560
Total Genus 188
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
188
sequence length
457
structure length
452
Chain Sequence
b'VDYSVDNPLFALSPLDGRYKRQTKALRAFFSEYGFFRYRVLVEVEYFTALCKDVPTIVPLRSVTDEQLQKLRKITLDCFSVSSAEEIKRLERVTNHDIKAVEYFIKERMDTCGLSHVTEFVHFGLTSQDINNTAIPMMIRDAIVTLYLPALDGIIGSLTSKLVDWDVPMLARTHGQPASPTNLAKEFVVWIERLREQRRQLCEVPTTGKFGGATGNFNAHLVAYPSVNWRAFADMFLAKYLGLKRQQATTQIENYDHLAALCDACARLHVILIDMCRDVWQYISMGFFKQKVKEGEVGSSTMPHKVNPIDFENAEGNLALSNALLNFFASKLPISRLQRDLTDSTVLRNLGVPIGHACVAFASISQGLEKLMISRETISRELSSNWAVVAEGIQTVLRRECYPKPYETLKKLTVTEEQVRNFINGLTDISDDVRAELLAITPFTYVGYVPRF'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Adenylosuccinate lyase
publication title Crystal Structure of Adenylosuccinate Lyase from Trypanosoma Brucei, Tb427tmp.160.5560
rcsb
source organism Trypanosoma brucei brucei
molecule tags Lyase
total genus 188
structure length 452
sequence length 457
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2012-03-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF08328 ASL_C Adenylosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4efcA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4efcA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4efcA02
1GK2A 2YIIA 1TJVA 3R6VA 2O6YA 3E04A 4EFCA 1C3UA 1Y2MA 1VDKA 4V2QA 4NLEA 1Q5NA 4FLCA 1FUQA 5D6BA 1FURA 2RJSA 4NSLA 5EYTA 2PTSA 3KDYA 2PFMA 1T6JA 2PTRA 4HGVA 4EEIA 4C5RA 4ADMA 1TJWA 4V2RA 2QGAB 3R6QA 1GKJA 3KDZA 1FUPA 1DOFA 4BAAA 1J3UA 2VD6A 2O7EA 1K7WA 2HVGA 1HY0A 4C6GA 5F92A 3GZHA 1JSWA 1W27A 3GTDA 2QVEA 1T6PA 1I0AA 3RRPA 2E9FA 1B8FA 4CQ5A 3OCEA 4MX2A 3CZOA 3RD8A 3C8TA 4C5SA 3NZ4A 5EYVA 2O7DA 1TJUA 2NYNA 1C3CA 2RJRA 4BABA 5F91A 1YFEA 3NO9A 4C5UA 1K62A 2J91A 1EB4A 2O78A 2OHYA 2O7BA 1GKMA 3R6YA 1YFMA 2X75A 1KQ7A 4APBA 2NYFA 1XWOA 2O7FA 1TJ7A 4FFXA 1DCNA 1AUWA 5HW2A 1FUOA 1U15A 3BHGA 3OCFA 1YISA 2FUSA 3QBPA 4APAA 3UNVA 1RE5A 1U16A 1HY1A 3TV2A 2PTQA 1GK3A 4ADLA
chains in the Genus database with same CATH superfamily
1GK2A 2YIIA 1TJVA 2JARA 3R6VA 1IW7D 3E04A 2O6YA 4IQJM 4EFCA 1C3UA 1Y2MA 1VDKA 1Z4QA 4V2QA 4NLEA 1Q5NA 4FLCA 1FUQA 5D6BA 1FURA 2RJSA 4NSLA 5EYTA 1Z4PX 4NFLA 2PTSA 3KDYA 1XL7A 5M0IA 2PFMA 1T6JA 2PTRA 3F4TA 1XL8A 4HGVA 4EEIA 4C5RA 2YV5A 4ADMA 1TJWA 1MH9A 4V2RA 2QGAB 3R6QA 1GKJA 1Q91A 4E88A 3KDZA 1FUPA 3CRVA 1DOFA 4BAAA 1J3UA 2VD6A 2O7EA 2VSFA 4YIKA 4L57A 1K7WA 2JAUA 2HVGA 1HY0A 4C6GA 5F92A 4MWOA 3GZHA 2VL7A 3U19A 1JSWA 1W27A 3GTDA 2QVEA 4YIHA 1T6PA 1I0AA 3RRPA 2E9FA 3CI0K 1B8FA 4CQ5A 3OCEA 4MX2A 3CZOA 3RD8A 3C8TA 3CRW1 4C5SA 1XLYA 3F4SA 4A15A 3NZ4A 5EYVA 2O7DA 3U13A 1T9HA 1TJUA 2NYNA 1C3CA 2RJRA 1XMDA 4BABA 2D27A 1YFEA 5F91A 5M0JA 3NO9A 4C5UA 4MUMA 1K62A 2J91A 1U0LA 1Z4IA 2FENA 1EB4A 2O78A 2OHYA 4L6CA 2O7BA 1GKMA 2D28C 3R6YA 1Z4MA 1YFMA 2X75A 1KQ7A 5H8WA 2RCNA 1Z4KA 2FELA 3F4RA 4APBA 2NYFA 1XWOA 4WNLA 2O7FA 1TJ7A 1Q92A 2I7DA 4FFXA 1Z4JA 1DCNA 1AUWA 5HW2A 1FUOA 1XMCA 4L6AA 1U15A 3BHGA 3OCFA 1YISA 1Z4LA 2FUSA 2JAOA 3QBPA 4APAA 3UNVA 1RE5A 1U16A 1HY1A 3TV2A 2PTQA 1GK3A 3BWVA 4ADLA 2JAWA
chains in the Genus database with same CATH topology
1GK2A 2YIIA 1TJVA 3R6VA 2O6YA 3E04A 4EFCA 1C3UA 1Y2MA 1VDKA 4V2QA 4NLEA 1Q5NA 4FLCA 1FUQA 5D6BA 1FURA 2RJSA 4NSLA 5EYTA 2PTSA 3KDYA 2PFMA 1T6JA 2PTRA 4HGVA 4EEIA 4C5RA 4ADMA 1TJWA 4V2RA 2QGAB 3R6QA 1GKJA 3KDZA 1FUPA 1DOFA 4BAAA 1J3UA 2VD6A 2O7EA 1K7WA 2HVGA 1HY0A 4C6GA 5F92A 3GZHA 1JSWA 1W27A 3GTDA 2QVEA 1T6PA 1I0AA 3RRPA 2E9FA 1B8FA 4CQ5A 3OCEA 4MX2A 3CZOA 3RD8A 3C8TA 4C5SA 3NZ4A 5EYVA 2O7DA 1TJUA 2NYNA 1C3CA 2RJRA 4BABA 5F91A 1YFEA 3NO9A 4C5UA 1K62A 2J91A 1EB4A 2O78A 2OHYA 2O7BA 1GKMA 3R6YA 1YFMA 2X75A 1KQ7A 4APBA 2NYFA 1XWOA 2O7FA 1TJ7A 4FFXA 1DCNA 1AUWA 5HW2A 1FUOA 1U15A 3BHGA 3OCFA 1YISA 2FUSA 3QBPA 4APAA 3UNVA 1RE5A 1U16A 1HY1A 3TV2A 2PTQA 1GK3A 4ADLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GK2 A;  2YII A;  1TJV A;  3R6V A;  2O6Y A;  3E04 A;  4EFC A;  1C3U A;  1Y2M A;  1VDK A;  4V2Q A;  4NLE A;  1Q5N A;  4FLC A;  1FUQ A;  5D6B A;  1FUR A;  2RJS A;  4NSL A;  5EYT A;  2PTS A;  3KDY A;  2PFM A;  1T6J A;  2PTR A;  4HGV A;  4EEI A;  4C5R A;  4ADM A;  1TJW A;  4V2R A;  2QGA B;  3R6Q A;  1GKJ A;  3KDZ A;  1FUP A;  1DOF A;  4BAA A;  1J3U A;  2VD6 A;  2O7E A;  1K7W A;  2HVG A;  1HY0 A;  4C6G A;  5F92 A;  3GZH A;  1JSW A;  1W27 A;  3GTD A;  2QVE A;  1T6P A;  1I0A A;  3RRP A;  2E9F A;  1B8F A;  4CQ5 A;  3OCE A;  4MX2 A;  3CZO A;  3RD8 A;  3C8T A;  4C5S A;  3NZ4 A;  5EYV A;  2O7D A;  1TJU A;  2NYN A;  1C3C A;  2RJR A;  4BAB A;  5F91 A;  1YFE A;  3NO9 A;  4C5U A;  1K62 A;  2J91 A;  1EB4 A;  2O78 A;  2OHY A;  2O7B A;  1GKM A;  3R6Y A;  1YFM A;  2X75 A;  1KQ7 A;  4APB A;  2NYF A;  1XWO A;  2O7F A;  1TJ7 A;  4FFX A;  1DCN A;  1AUW A;  5HW2 A;  1FUO A;  1U15 A;  3BHG A;  3OCF A;  1YIS A;  2FUS A;  3QBP A;  4APA A;  3UNV A;  1RE5 A;  1U16 A;  1HY1 A;  3TV2 A;  2PTQ A;  1GK3 A;  4ADL A; 
#chains in the Genus database with same CATH topology
 1GK2 A;  2YII A;  1TJV A;  2JAR A;  3R6V A;  1IW7 D;  3E04 A;  2O6Y A;  4IQJ M;  4EFC A;  1C3U A;  1Y2M A;  1VDK A;  1Z4Q A;  4V2Q A;  4NLE A;  1Q5N A;  4FLC A;  1FUQ A;  5D6B A;  1FUR A;  2RJS A;  4NSL A;  5EYT A;  1Z4P X;  4NFL A;  2PTS A;  3KDY A;  1XL7 A;  5M0I A;  2PFM A;  1T6J A;  2PTR A;  3F4T A;  1XL8 A;  4HGV A;  4EEI A;  4C5R A;  2YV5 A;  4ADM A;  1TJW A;  1MH9 A;  4V2R A;  2QGA B;  3R6Q A;  1GKJ A;  1Q91 A;  4E88 A;  3KDZ A;  1FUP A;  3CRV A;  1DOF A;  4BAA A;  1J3U A;  2VD6 A;  2O7E A;  2VSF A;  4YIK A;  4L57 A;  1K7W A;  2JAU A;  2HVG A;  1HY0 A;  4C6G A;  5F92 A;  4MWO A;  3GZH A;  2VL7 A;  3U19 A;  1JSW A;  1W27 A;  3GTD A;  2QVE A;  4YIH A;  1T6P A;  1I0A A;  3RRP A;  2E9F A;  3CI0 K;  1B8F A;  4CQ5 A;  3OCE A;  4MX2 A;  3CZO A;  3RD8 A;  3C8T A;  3CRW 1;  4C5S A;  1XLY A;  3F4S A;  4A15 A;  3NZ4 A;  5EYV A;  2O7D A;  3U13 A;  1T9H A;  1TJU A;  2NYN A;  1C3C A;  2RJR A;  1XMD A;  4BAB A;  2D27 A;  1YFE A;  5F91 A;  5M0J A;  3NO9 A;  4C5U A;  4MUM A;  1K62 A;  2J91 A;  1U0L A;  1Z4I A;  2FEN A;  1EB4 A;  2O78 A;  2OHY A;  4L6C A;  2O7B A;  1GKM A;  2D28 C;  3R6Y A;  1Z4M A;  1YFM A;  2X75 A;  1KQ7 A;  5H8W A;  2RCN A;  1Z4K A;  2FEL A;  3F4R A;  4APB A;  2NYF A;  1XWO A;  4WNL A;  2O7F A;  1TJ7 A;  1Q92 A;  2I7D A;  4FFX A;  1Z4J A;  1DCN A;  1AUW A;  5HW2 A;  1FUO A;  1XMC A;  4L6A A;  1U15 A;  3BHG A;  3OCF A;  1YIS A;  1Z4L A;  2FUS A;  2JAO A;  3QBP A;  4APA A;  3UNV A;  1RE5 A;  1U16 A;  1HY1 A;  3TV2 A;  2PTQ A;  1GK3 A;  3BWV A;  4ADL A;  2JAW A; 
#chains in the Genus database with same CATH homology
 1GK2 A;  2YII A;  1TJV A;  3R6V A;  2O6Y A;  3E04 A;  4EFC A;  1C3U A;  1Y2M A;  1VDK A;  4V2Q A;  4NLE A;  1Q5N A;  4FLC A;  1FUQ A;  5D6B A;  1FUR A;  2RJS A;  4NSL A;  5EYT A;  2PTS A;  3KDY A;  2PFM A;  1T6J A;  2PTR A;  4HGV A;  4EEI A;  4C5R A;  4ADM A;  1TJW A;  4V2R A;  2QGA B;  3R6Q A;  1GKJ A;  3KDZ A;  1FUP A;  1DOF A;  4BAA A;  1J3U A;  2VD6 A;  2O7E A;  1K7W A;  2HVG A;  1HY0 A;  4C6G A;  5F92 A;  3GZH A;  1JSW A;  1W27 A;  3GTD A;  2QVE A;  1T6P A;  1I0A A;  3RRP A;  2E9F A;  1B8F A;  4CQ5 A;  3OCE A;  4MX2 A;  3CZO A;  3RD8 A;  3C8T A;  4C5S A;  3NZ4 A;  5EYV A;  2O7D A;  1TJU A;  2NYN A;  1C3C A;  2RJR A;  4BAB A;  5F91 A;  1YFE A;  3NO9 A;  4C5U A;  1K62 A;  2J91 A;  1EB4 A;  2O78 A;  2OHY A;  2O7B A;  1GKM A;  3R6Y A;  1YFM A;  2X75 A;  1KQ7 A;  4APB A;  2NYF A;  1XWO A;  2O7F A;  1TJ7 A;  4FFX A;  1DCN A;  1AUW A;  5HW2 A;  1FUO A;  1U15 A;  3BHG A;  3OCF A;  1YIS A;  2FUS A;  3QBP A;  4APA A;  3UNV A;  1RE5 A;  1U16 A;  1HY1 A;  3TV2 A;  2PTQ A;  1GK3 A;  4ADL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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