4EFCA

Crystal structure of adenylosuccinate lyase from trypanosoma brucei, tb427tmp.160.5560
Total Genus 188
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
188
sequence length
457
structure length
452
Chain Sequence
VDYSVDNPLFALSPLDGRYKRQTKALRAFFSEYGFFRYRVLVEVEYFTALCKDVPTIVPLRSVTDEQLQKLRKITLDCFSVSSAEEIKRLERVTNHDIKAVEYFIKERMDTCGLSHVTEFVHFGLTSQDINNTAIPMMIRDAIVTLYLPALDGIIGSLTSKLVDWDVPMLARTHGQPASPTNLAKEFVVWIERLREQRRQLCEVPTTGKFGGATGNFNAHLVAYPSVNWRAFADMFLAKYLGLKRQQATTQIENYDHLAALCDACARLHVILIDMCRDVWQYISMGFFKQKVKEGEVGSSTMPHKVNPIDFENAEGNLALSNALLNFFASKLPISRLQRDLTDSTVLRNLGVPIGHACVAFASISQGLEKLMISRETISRELSSNWAVVAEGIQTVLRRECYPKPYETLKKLTVTEEQVRNFINGLTDISDDVRAELLAITPFTYVGYVPRF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Adenylosuccinate lyase
publication title Crystal Structure of Adenylosuccinate Lyase from Trypanosoma Brucei, Tb427tmp.160.5560
rcsb
source organism Trypanosoma brucei brucei
molecule tags Lyase
total genus 188
structure length 452
sequence length 457
chains with identical sequence B
ec nomenclature ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date 2012-03-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF08328 ASL_C Adenylosuccinate lyase C-terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4efcA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4efcA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4efcA02
1JSWA 1GK2A 4BAAA 1AUWA 1TJVA 1FUPA 1Q5NA 4FFXA 2O7FA 3OCEA 1J3UA 4NSLA 1DOFA 1K7WA 3R6YA 3NO9A 1TJ7A 2PTSA 3GZHA 1U16A 3RD8A 2NYNA 3OCFA 4EEIA 1GKMA 1DCNA 1FUQA 4CQ5A 5D6BA 3C8TA 1HY1A 1U15A 2O78A 2O7BA 2E9FA 1B8FA 3RRPA 3GTDA 4APBA 2O7DA 4V2RA 1T6JA 5EYTA 1YISA 1KQ7A 2QGAB 1EB4A 2QVEA 1YFEA 3QBPA 4C5RA 1XWOA 4EFCA 5F92A 3BHGA 1W27A 2HVGA 4BABA 3E04A 1GKJA 1K62A 3UNVA 1FUOA 4C6GA 5F91A 2O6YA 5HW2A 1TJWA 1T6PA 4MX2A 2PTRA 4ADLA 5EYVA 1C3UA 4C5UA 4ADMA 2J91A 3NZ4A 2RJSA 2YIIA 2RJRA 4HGVA 4FLCA 4C5SA 1YFMA 1C3CA 1TJUA 1GK3A 2FUSA 3KDYA 3KDZA 3CZOA 3TV2A 2VD6A 1RE5A 4NLEA 2OHYA 2O7EA 1I0AA 1VDKA 2PFMA 2PTQA 1HY0A 3R6VA 2X75A 1Y2MA 2NYFA 1FURA 4V2QA 3R6QA 4APAA
chains in the Genus database with same CATH superfamily
1JSWA 1GK2A 4BAAA 1AUWA 1TJVA 1FUPA 2JAOA 3F4TA 1Q5NA 1XMDA 4FFXA 2O7FA 3OCEA 1J3UA 4NSLA 4L57A 3F4RA 1DOFA 4MWOA 3F4SA 1K7WA 1XL8A 2YV5A 1Z4LA 3NO9A 3U13A 3R6YA 3CRVA 1TJ7A 2PTSA 3GZHA 1U16A 3RD8A 2NYNA 3OCFA 1Z4MA 4EEIA 1GKMA 1DCNA 1FUQA 4CQ5A 2JAWA 3C8TA 5D6BA 1HY1A 1U15A 2O78A 1MH9A 1Q92A 4E88A 1T9HA 2O7BA 2VSFA 4IQJM 2E9FA 1B8FA 3RRPA 3GTDA 4APBA 1Z4KA 2O7DA 4V2RA 1T6JA 5EYTA 1YISA 5M0JA 1KQ7A 4NFLA 2FENA 2QGAB 1EB4A 2QVEA 1YFEA 3QBPA 4C5RA 1XWOA 4EFCA 1IW7D 5F92A 3BHGA 4YIKA 1W27A 2HVGA 4BABA 3E04A 1GKJA 1K62A 3UNVA 1FUOA 4C6GA 1Z4IA 5F91A 2O6YA 5HW2A 1TJWA 2I7DA 4L6CA 1T6PA 4MUMA 4MX2A 2PTRA 4ADLA 5EYVA 1C3UA 2VL7A 4C5UA 4ADMA 2J91A 2RCNA 3NZ4A 2RJSA 2YIIA 3CI0K 2RJRA 2D27A 4HGVA 1Z4QA 1XL7A 4FLCA 1Z4JA 4C5SA 5M0IA 2FELA 1YFMA 1C3CA 1TJUA 1GK3A 3U19A 1Q91A 2FUSA 3KDYA 3KDZA 5H8WA 2JARA 3TV2A 2VD6A 3CZOA 1RE5A 4YIHA 4NLEA 2OHYA 2JAUA 1Z4PX 2D28C 2O7EA 1U0LA 4A15A 1I0AA 1VDKA 2PFMA 2PTQA 1XMCA 1HY0A 3R6VA 2X75A 3BWVA 1XLYA 3CRW1 1Y2MA 2NYFA 1FURA 4V2QA 3R6QA 4WNLA 4L6AA 4APAA
chains in the Genus database with same CATH topology
1JSWA 1GK2A 4BAAA 1AUWA 1TJVA 1FUPA 1Q5NA 4FFXA 2O7FA 3OCEA 1J3UA 4NSLA 1DOFA 1K7WA 3R6YA 3NO9A 1TJ7A 2PTSA 3GZHA 1U16A 3RD8A 2NYNA 3OCFA 4EEIA 1GKMA 1DCNA 1FUQA 4CQ5A 5D6BA 3C8TA 1HY1A 1U15A 2O78A 2O7BA 2E9FA 1B8FA 3RRPA 3GTDA 4APBA 2O7DA 4V2RA 1T6JA 5EYTA 1YISA 1KQ7A 2QGAB 1EB4A 2QVEA 1YFEA 3QBPA 4C5RA 1XWOA 4EFCA 5F92A 3BHGA 1W27A 2HVGA 4BABA 3E04A 1GKJA 1K62A 3UNVA 1FUOA 4C6GA 5F91A 2O6YA 5HW2A 1TJWA 1T6PA 4MX2A 2PTRA 4ADLA 5EYVA 1C3UA 4C5UA 4ADMA 2J91A 3NZ4A 2RJSA 2YIIA 2RJRA 4HGVA 4FLCA 4C5SA 1YFMA 1C3CA 1TJUA 1GK3A 2FUSA 3KDYA 3KDZA 3CZOA 3TV2A 2VD6A 1RE5A 4NLEA 2OHYA 2O7EA 1I0AA 1VDKA 2PFMA 2PTQA 1HY0A 3R6VA 2X75A 1Y2MA 2NYFA 1FURA 4V2QA 3R6QA 4APAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JSW A;  1GK2 A;  4BAA A;  1AUW A;  1TJV A;  1FUP A;  1Q5N A;  4FFX A;  2O7F A;  3OCE A;  1J3U A;  4NSL A;  1DOF A;  1K7W A;  3R6Y A;  3NO9 A;  1TJ7 A;  2PTS A;  3GZH A;  1U16 A;  3RD8 A;  2NYN A;  3OCF A;  4EEI A;  1GKM A;  1DCN A;  1FUQ A;  4CQ5 A;  5D6B A;  3C8T A;  1HY1 A;  1U15 A;  2O78 A;  2O7B A;  2E9F A;  1B8F A;  3RRP A;  3GTD A;  4APB A;  2O7D A;  4V2R A;  1T6J A;  5EYT A;  1YIS A;  1KQ7 A;  2QGA B;  1EB4 A;  2QVE A;  1YFE A;  3QBP A;  4C5R A;  1XWO A;  4EFC A;  5F92 A;  3BHG A;  1W27 A;  2HVG A;  4BAB A;  3E04 A;  1GKJ A;  1K62 A;  3UNV A;  1FUO A;  4C6G A;  5F91 A;  2O6Y A;  5HW2 A;  1TJW A;  1T6P A;  4MX2 A;  2PTR A;  4ADL A;  5EYV A;  1C3U A;  4C5U A;  4ADM A;  2J91 A;  3NZ4 A;  2RJS A;  2YII A;  2RJR A;  4HGV A;  4FLC A;  4C5S A;  1YFM A;  1C3C A;  1TJU A;  1GK3 A;  2FUS A;  3KDY A;  3KDZ A;  3CZO A;  3TV2 A;  2VD6 A;  1RE5 A;  4NLE A;  2OHY A;  2O7E A;  1I0A A;  1VDK A;  2PFM A;  2PTQ A;  1HY0 A;  3R6V A;  2X75 A;  1Y2M A;  2NYF A;  1FUR A;  4V2Q A;  3R6Q A;  4APA A; 
#chains in the Genus database with same CATH topology
 1JSW A;  1GK2 A;  4BAA A;  1AUW A;  1TJV A;  1FUP A;  2JAO A;  3F4T A;  1Q5N A;  1XMD A;  4FFX A;  2O7F A;  3OCE A;  1J3U A;  4NSL A;  4L57 A;  3F4R A;  1DOF A;  4MWO A;  3F4S A;  1K7W A;  1XL8 A;  2YV5 A;  1Z4L A;  3NO9 A;  3U13 A;  3R6Y A;  3CRV A;  1TJ7 A;  2PTS A;  3GZH A;  1U16 A;  3RD8 A;  2NYN A;  3OCF A;  1Z4M A;  4EEI A;  1GKM A;  1DCN A;  1FUQ A;  4CQ5 A;  2JAW A;  3C8T A;  5D6B A;  1HY1 A;  1U15 A;  2O78 A;  1MH9 A;  1Q92 A;  4E88 A;  1T9H A;  2O7B A;  2VSF A;  4IQJ M;  2E9F A;  1B8F A;  3RRP A;  3GTD A;  4APB A;  1Z4K A;  2O7D A;  4V2R A;  1T6J A;  5EYT A;  1YIS A;  5M0J A;  1KQ7 A;  4NFL A;  2FEN A;  2QGA B;  1EB4 A;  2QVE A;  1YFE A;  3QBP A;  4C5R A;  1XWO A;  4EFC A;  1IW7 D;  5F92 A;  3BHG A;  4YIK A;  1W27 A;  2HVG A;  4BAB A;  3E04 A;  1GKJ A;  1K62 A;  3UNV A;  1FUO A;  4C6G A;  1Z4I A;  5F91 A;  2O6Y A;  5HW2 A;  1TJW A;  2I7D A;  4L6C A;  1T6P A;  4MUM A;  4MX2 A;  2PTR A;  4ADL A;  5EYV A;  1C3U A;  2VL7 A;  4C5U A;  4ADM A;  2J91 A;  2RCN A;  3NZ4 A;  2RJS A;  2YII A;  3CI0 K;  2RJR A;  2D27 A;  4HGV A;  1Z4Q A;  1XL7 A;  4FLC A;  1Z4J A;  4C5S A;  5M0I A;  2FEL A;  1YFM A;  1C3C A;  1TJU A;  1GK3 A;  3U19 A;  1Q91 A;  2FUS A;  3KDY A;  3KDZ A;  5H8W A;  2JAR A;  3TV2 A;  2VD6 A;  3CZO A;  1RE5 A;  4YIH A;  4NLE A;  2OHY A;  2JAU A;  1Z4P X;  2D28 C;  2O7E A;  1U0L A;  4A15 A;  1I0A A;  1VDK A;  2PFM A;  2PTQ A;  1XMC A;  1HY0 A;  3R6V A;  2X75 A;  3BWV A;  1XLY A;  3CRW 1;  1Y2M A;  2NYF A;  1FUR A;  4V2Q A;  3R6Q A;  4WNL A;  4L6A A;  4APA A; 
#chains in the Genus database with same CATH homology
 1JSW A;  1GK2 A;  4BAA A;  1AUW A;  1TJV A;  1FUP A;  1Q5N A;  4FFX A;  2O7F A;  3OCE A;  1J3U A;  4NSL A;  1DOF A;  1K7W A;  3R6Y A;  3NO9 A;  1TJ7 A;  2PTS A;  3GZH A;  1U16 A;  3RD8 A;  2NYN A;  3OCF A;  4EEI A;  1GKM A;  1DCN A;  1FUQ A;  4CQ5 A;  5D6B A;  3C8T A;  1HY1 A;  1U15 A;  2O78 A;  2O7B A;  2E9F A;  1B8F A;  3RRP A;  3GTD A;  4APB A;  2O7D A;  4V2R A;  1T6J A;  5EYT A;  1YIS A;  1KQ7 A;  2QGA B;  1EB4 A;  2QVE A;  1YFE A;  3QBP A;  4C5R A;  1XWO A;  4EFC A;  5F92 A;  3BHG A;  1W27 A;  2HVG A;  4BAB A;  3E04 A;  1GKJ A;  1K62 A;  3UNV A;  1FUO A;  4C6G A;  5F91 A;  2O6Y A;  5HW2 A;  1TJW A;  1T6P A;  4MX2 A;  2PTR A;  4ADL A;  5EYV A;  1C3U A;  4C5U A;  4ADM A;  2J91 A;  3NZ4 A;  2RJS A;  2YII A;  2RJR A;  4HGV A;  4FLC A;  4C5S A;  1YFM A;  1C3C A;  1TJU A;  1GK3 A;  2FUS A;  3KDY A;  3KDZ A;  3CZO A;  3TV2 A;  2VD6 A;  1RE5 A;  4NLE A;  2OHY A;  2O7E A;  1I0A A;  1VDK A;  2PFM A;  2PTQ A;  1HY0 A;  3R6V A;  2X75 A;  1Y2M A;  2NYF A;  1FUR A;  4V2Q A;  3R6Q A;  4APA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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