4EFSA

Human mmp12 in complex with l-glutamate motif inhibitor
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
159
structure length
159
Chain Sequence
MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Simple pseudo-dipeptides with a P2' glutamate: a novel inhibitor family of matrix metalloproteases and other metzincins.
pubmed doi rcsb
molecule keywords Macrophage metalloelastase
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
total genus 43
structure length 159
sequence length 159
ec nomenclature ec 3.4.24.65: Macrophage elastase.
pdb deposition date 2012-03-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4efsA00
1HFCA 1JKYA 1ROSA 2O3EA 3U1RA 1XFZA 1R54A 4GWNA 3SHIA 2W0DA 3E8RA 1K7QA 4H84A 4XM7A 1PWWA 1XFUA 1SU3A 1EB6A 4GR0A 1CXVA 2D1NA 2MLSA 1BM6A 4EFSA 2X7MA 3HY7A 1OO9A 2ERQA 1L6JA 1CGEA 2EROA 1BUVM 1CGLA 2O36A 1Y93A 2DDYA 2J0TA 1ZTQA 2Z2DA 3EDGA 3KMEA 1KUHA 2K2GA 5BOTA 4PKRA 1A86A 1XUCA 1H71P 1SMPA 1SATA 1GO8P 1GKDA 2OY2A 4PKTA 1UTZA 1JAOA 5H8XA 4H1QA 3LJGA 1HTDA 3O64A 2MZHA 3VI1A 1GKCA 1ZXCA 2X3CA 1R1JA 2N8RA 2JSDA 4JQGA 3ZVSA 2KRJA 3HB2P 5BPAA 4PKVA 3LMCA 4PKUA 2POJA 4GR3A 5D3CA 2MLRA 3F16A 2OXZA 1ATLA 1KAPP 4H82A 3DWBA 1JAQA 1I76A 3V96B 1OM8A 2FV5A 4JP4A 4WF6A 1CIZA 1AKLA 3B8ZA 2WOAA 3EDZA 1PWQA 2OZRA 4IN9A 1SRPA 5L79A 2A8HA 4DV8A 1ZXVA 1MMRA 4ZR5A 4WZVA 1G05A 5D1UA 3LEAA 5D7WA 2MZEA 1QICA 1MMBA 1DTHA 3ELMA 5I2ZA 2L0RA 1BIWA 5BOYA 1A85A 1CGFA 2TCLA 1MNCA 3F19A 3ZXHA 5L7FA 2RJQA 2CKIA 1MMQA 1GE5A 3HYGA 3HBVP 3N2VA 3LILA 2X3BA 1JIZA 4AYKA 1B8YA 3O2XA 1JAPA 1HV5A 1EAKA 1CK7A 1XFVA 3TSKA 3WV2A 2YIGA 1ASTA 1KUGA 3USNA 5B5OA 1HFSA 4CTHA 3UVCA 2AIGP 1KUIA 1G12A 4QKZA 3N2UA 4AUOA 1CAQA 3DSLA 2USNA 1BSWA 3LE9A 2OVZA 1C3IA 1OS9A 3TT4A 3DPEA 1KUKA 1Z3JA 4L63A 1SLMA 1IAAA 2OW0A 4G9LA 1XUDA 3HBUP 1GE7A 4JIJA 1PWPA 1MMPA 1QJIA 1OS2A 4I03A 3LIRA 3TVCA 5B5PA 1R1HA 4IJOA 3OHLA 3EDIA 3P24A 1OM7A 1USNA 4H76A 3B92A 3EWJA 1ZP5A 3LUNA 1HY7A 2CLTA 5D1TA 1KBCA 4ON1A 4DF9A 4DD8A 5D1SA 3F18A 5I43A 3G42A 3KRYA 1PWVA 4L6TA 3KHIA 1AF0A 3LIKA 3KECA 3RTTA 3KMCA 4XM8A 5CUHA 1CQRA 1FBLA 1GXDA 1BUDA 1D8FA 1YQYA 1OM6A 1G9KA 1JK3A 3Q2GA 2FV9A 2OI0A 1XFYA 2QPJA 1ZS0A 3K7NA 1UEAA 2I47A 3P1VA 1Y0VA 1JH1A 4JA1A 3G5CA 1R1IA 5I12A 1IABA 3B2ZA 1QUAA 2ERPA 4H2EA 1QIAA 2OXWA 4H3XA 3WV1A 3MA2A 2XS4A 5LABA 3LKAA 2D1OA 4IUWA 2W15A 1IAGA 1G4KA 1S4BP 1XFWA 3ZUKA 1GE6A 1PWUA 1QIBA 4FVLA 1YP1A 1IACA 1R55A 4J4MA 1HOVA 2OY4A 1SLNA 2V4BA 3VTGA 1BZSA 1JANA 2DW2A 3AYUA 4R3VA 2XS3A 2W13A 2DDFA 3F17A 1K7GA 3LQBA 2W12A 1ZVXA 4WK7A 1C7KA 2DW0A 2OXUA 2Y6CA 5I4OA 1Y8JA 2E3XA 1BQQM 2J83A 4GQLA 4H49A 2OW9A 2YB9A 4PKSA 1WNIA 4GF1A 1FM1A 2JNPA 1IAEA 2RJPA 2K9CA 1G49A 2WO8A 3LK8A 4WKIA 4FXQA 3EHXA 1UMSA 3Q2HA 2SRTA 5JMYA 4GUYA 3EDHA 2WO9A 2JT5A 3F1AA 1Q3AA 2HU6A 1BKCA 3DPFA 4XCTA 3OHOA 2OW2A 3KEJA 4L19A 4G0DA 4A7BA 830CA 3KEKA 1D5JA 4DPEA 3DNGA 1ND1A 3NX7A 2X3AA 3WV3A 1UTTA 3TS4A 1J7NA 1I73A 1K7IA 4FXYP 5I0LA 2JT6A 3AIGA 1B3DA 4I35A 1OMJA 1BQOA 4JPAA 2Y6DA 4WKEA 3RTSA 1FLSA 1O0QA 3CKIA 1D7XA 3HDAP 4GWMA 4HMAA 1JJ9A 4Q1LA 966CA 4AXQA 3EHYA 3K7LA 5CXAA 3KWVC 1UMTA 4A3WA 1JIWP 2JIHA 5CZMA 1KUFA 3LQ0A 3GBOA 1GO7P 1IADA 1RM8A 4FU4A 1YCMA 2E2DA 3L0TA 4XBHA 1BKCE 4PKQA 4AIGA 1BKCI 1D8MA 3DL1A 3AYKA 1I1IP 1XFXA 1EUBA 3LUMA 456CA 3F15A 3HDBA 5D2BA 1AYKA 1DMTA 1C8TA 4XM6A 3I7IA 2MZIA 1QJJA 3HY9A 4GR8A 1XURA 3L0VA 2W14A 2OW1A 2DW1A 1RMZA 1YOUA 3LGPA 3LJTA 3BA0A 4PKWA 4ILWD 4HX3A 2PJTA 3I7GA 2OVXA 4H30A 1O0TA 5I3MA 2AYKA 3LJZA
chains in the Genus database with same CATH superfamily
1HFCA 1JKYA 1ROSA 2O3EA 3U1RA 1XFZA 1R54A 4GWNA 3SHIA 2W0DA 3E8RA 1K7QA 4H84A 4XM7A 1PWWA 1XFUA 1SU3A 1EB6A 4GR0A 1CXVA 2D1NA 2MLSA 1BM6A 4EFSA 2X7MA 3HY7A 1OO9A 2ERQA 4L7AA 1L6JA 1CGEA 2EROA 1BUVM 1CGLA 2O36A 1Y93A 2DDYA 2J0TA 1ZTQA 2Z2DA 3EDGA 3KMEA 1KUHA 2K2GA 5BOTA 4PKRA 1A86A 3DTIA 1XUCA 1XM5A 1H71P 1SMPA 1SATA 1GO8P 1GKDA 2OY2A 4PKTA 1UTZA 1JAOA 5H8XA 4H1QA 3LJGA 1HTDA 3O64A 2MZHA 3VI1A 1GKCA 1ZXCA 2X3CA 1R1JA 2N8RA 2JSDA 4JQGA 3ZVSA 2KRJA 3HB2P 5BPAA 4PKVA 3LMCA 4PKUA 2POJA 4GR3A 5D3CA 2MLRA 3F16A 2OXZA 1ATLA 1KAPP 4H82A 3DWBA 1JAQA 1I76A 3V96B 1OM8A 2FV5A 4JP4A 4WF6A 1CIZA 1AKLA 3B8ZA 2WOAA 3EDZA 1PWQA 2OZRA 4IN9A 1SRPA 5L79A 2A8HA 4DV8A 1ZXVA 1MMRA 4ZR5A 4WZVA 1G05A 5D1UA 3LEAA 5D7WA 2MZEA 1QICA 1MMBA 1DTHA 3ELMA 5I2ZA 2L0RA 1BIWA 5BOYA 1A85A 1CGFA 2TCLA 1MNCA 3F19A 3ZXHA 5L7FA 2RJQA 2CKIA 1MMQA 1GE5A 3HYGA 3HBVP 3N2VA 3LILA 2X3BA 1JIZA 4AYKA 1B8YA 3O2XA 1JAPA 1HV5A 1EAKA 1CK7A 1XFVA 3TSKA 3WV2A 2YIGA 1ASTA 1KUGA 1TVIA 3USNA 5B5OA 1HFSA 4CTHA 3UVCA 2AIGP 1KUIA 3DTEA 1G12A 4QKZA 3N2UA 4AUOA 1CAQA 3DSLA 2USNA 1BSWA 3LE9A 2OVZA 1C3IA 1OS9A 3TT4A 3DPEA 1KUKA 1Z3JA 4L63A 1SLMA 1IAAA 2OW0A 4G9LA 1XUDA 3HBUP 1GE7A 4JIJA 1PWPA 1MMPA 1QJIA 1OS2A 4I03A 3LIRA 3TVCA 5B5PA 1R1HA 4IJOA 3OHLA 3EDIA 3P24A 1OM7A 1USNA 4H76A 3B92A 3EWJA 1ZP5A 3LUNA 1HY7A 2CLTA 5D1TA 1KBCA 4ON1A 4DF9A 4DD8A 5D1SA 3F18A 5I43A 3G42A 3KRYA 1PWVA 4L6TA 3KHIA 1AF0A 3LIKA 3KECA 3RTTA 3KMCA 4XM8A 5CUHA 1CQRA 1FBLA 1GXDA 1BUDA 1D8FA 1YQYA 1OM6A 1G9KA 1JK3A 3Q2GA 2FV9A 2OI0A 1XFYA 2QPJA 1ZS0A 3K7NA 1UEAA 2I47A 3P1VA 1Y0VA 1JH1A 4JA1A 3G5CA 1R1IA 5I12A 1IABA 3B2ZA 1QUAA 2ERPA 4H2EA 1QIAA 2OXWA 4H3XA 3WV1A 3MA2A 2XS4A 5LABA 3LKAA 2D1OA 4IUWA 2W15A 1IAGA 1G4KA 1S4BP 1XFWA 3ZUKA 1GE6A 1PWUA 1QIBA 4FVLA 1YP1A 1IACA 1R55A 4J4MA 1HOVA 2OY4A 1SLNA 2V4BA 3VTGA 1BZSA 1JANA 2DW2A 3AYUA 4R3VA 2XS3A 2W13A 2DDFA 3F17A 1K7GA 3LQBA 2W12A 1ZVXA 4WK7A 1C7KA 2DW0A 2OXUA 2Y6CA 5I4OA 1Y8JA 2E3XA 1BQQM 2J83A 4GQLA 4H49A 2OW9A 2YB9A 4PKSA 1WNIA 4GF1A 1FM1A 2JNPA 1IAEA 2RJPA 2K9CA 1G49A 2WO8A 3LK8A 4WKIA 4FXQA 3EHXA 1UMSA 3Q2HA 2SRTA 5JMYA 4GUYA 3EDHA 2WO9A 2JT5A 3F1AA 1Q3AA 2HU6A 1BKCA 3DPFA 4XCTA 3OHOA 2OW2A 3KEJA 4L19A 4G0DA 4A7BA 830CA 3KEKA 1D5JA 4DPEA 3DNGA 1ND1A 3NX7A 2X3AA 3WV3A 1UTTA 3TS4A 1J7NA 1I73A 1K7IA 4FXYP 5I0LA 2JT6A 3AIGA 1B3DA 1XAXA 4I35A 1OMJA 1BQOA 4JPAA 2Y6DA 4WKEA 3RTSA 1FLSA 1O0QA 3CKIA 1D7XA 3HDAP 4GWMA 4HMAA 1JJ9A 4Q1LA 966CA 4AXQA 3EHYA 3K7LA 3DTKA 5CXAA 3KWVC 1UMTA 4A3WA 1JIWP 2YUFA 2JIHA 5CZMA 1KUFA 3LQ0A 3GBOA 1GO7P 1IADA 1RM8A 4FU4A 1YCMA 2E2DA 3L0TA 4XBHA 1BKCE 4PKQA 4AIGA 1BKCI 1D8MA 3DL1A 3AYKA 1I1IP 1XFXA 1EUBA 3LUMA 456CA 3F15A 3HDBA 5D2BA 1AYKA 1DMTA 1C8TA 4XM6A 3I7IA 2MZIA 1QJJA 3HY9A 4GR8A 1XURA 3L0VA 2W14A 2OW1A 2DW1A 1RMZA 1YOUA 3LGPA 3LJTA 3BA0A 4PKWA 4ILWD 4HX3A 2PJTA 3I7GA 2OVXA 4H30A 1O0TA 5I3MA 2AYKA 1OZ9A 3LJZA
chains in the Genus database with same CATH topology
1HFCA 1JKYA 1ROSA 2O3EA 3U1RA 1XFZA 1R54A 4GWNA 3SHIA 2W0DA 3E8RA 1K7QA 4H84A 4XM7A 1PWWA 1XFUA 1SU3A 1EB6A 4GR0A 1CXVA 2D1NA 2MLSA 1BM6A 4EFSA 2X7MA 3HY7A 1OO9A 2ERQA 4L7AA 1L6JA 1CGEA 2EROA 1BUVM 1CGLA 2O36A 1Y93A 2DDYA 2J0TA 1ZTQA 2Z2DA 3EDGA 3KMEA 1KUHA 2K2GA 5BOTA 4PKRA 1A86A 3DTIA 1XUCA 1H71P 1SMPA 1SATA 1GO8P 1GKDA 2OY2A 4PKTA 1UTZA 1JAOA 5H8XA 4H1QA 3LJGA 1HTDA 3O64A 2MZHA 3VI1A 1GKCA 1ZXCA 2X3CA 1R1JA 2N8RA 2JSDA 4JQGA 3ZVSA 2KRJA 3HB2P 5BPAA 4PKVA 3LMCA 4PKUA 2POJA 4GR3A 5D3CA 2MLRA 3F16A 2OXZA 1ATLA 1KAPP 4H82A 3DWBA 1JAQA 1I76A 3V96B 1OM8A 2FV5A 4JP4A 4WF6A 1CIZA 1AKLA 3B8ZA 2WOAA 3EDZA 1PWQA 2OZRA 4IN9A 1SRPA 5L79A 2A8HA 4DV8A 1ZXVA 1MMRA 4ZR5A 4WZVA 1G05A 5D1UA 3LEAA 5D7WA 2MZEA 1QICA 1MMBA 1DTHA 3ELMA 5I2ZA 2L0RA 1BIWA 5BOYA 1A85A 1CGFA 2TCLA 1MNCA 3F19A 3ZXHA 5L7FA 2RJQA 2CKIA 1MMQA 1GE5A 3HYGA 3HBVP 3N2VA 3LILA 2X3BA 1JIZA 4AYKA 1B8YA 3O2XA 1JAPA 1HV5A 1EAKA 1CK7A 1XFVA 3TSKA 3WV2A 2YIGA 1ASTA 1KUGA 3USNA 5B5OA 1HFSA 4CTHA 3UVCA 2AIGP 1KUIA 3DTEA 1G12A 4QKZA 3N2UA 4AUOA 1CAQA 3DSLA 2USNA 1BSWA 3LE9A 2OVZA 1C3IA 1OS9A 3TT4A 3DPEA 1KUKA 1Z3JA 4L63A 1SLMA 1IAAA 2OW0A 4G9LA 1XUDA 3HBUP 1GE7A 4JIJA 1PWPA 1MMPA 1QJIA 1OS2A 4I03A 3LIRA 3TVCA 5B5PA 1R1HA 4IJOA 3OHLA 3EDIA 3P24A 1OM7A 1USNA 4H76A 3B92A 3EWJA 1ZP5A 3LUNA 1HY7A 2CLTA 5D1TA 1KBCA 4ON1A 4DF9A 4DD8A 5D1SA 3F18A 5I43A 3G42A 3KRYA 1PWVA 4L6TA 3KHIA 1AF0A 3LIKA 3KECA 3RTTA 3KMCA 4XM8A 5CUHA 1CQRA 1FBLA 1GXDA 1BUDA 1D8FA 1YQYA 1OM6A 1G9KA 1JK3A 3Q2GA 2FV9A 2OI0A 1XFYA 2QPJA 1ZS0A 3K7NA 1UEAA 2I47A 3P1VA 1Y0VA 1JH1A 4JA1A 3G5CA 1R1IA 5I12A 1IABA 3B2ZA 1QUAA 2ERPA 4H2EA 1QIAA 2OXWA 4H3XA 3WV1A 3MA2A 2XS4A 5LABA 3LKAA 2D1OA 4IUWA 2W15A 1IAGA 1G4KA 1S4BP 1XFWA 3ZUKA 1GE6A 1PWUA 1QIBA 4FVLA 1YP1A 1IACA 1R55A 4J4MA 1HOVA 2OY4A 1SLNA 2V4BA 3VTGA 1BZSA 1JANA 2DW2A 3AYUA 4R3VA 2XS3A 2W13A 2DDFA 3F17A 1K7GA 3LQBA 2W12A 1ZVXA 4WK7A 1C7KA 2DW0A 2OXUA 2Y6CA 5I4OA 1Y8JA 2E3XA 1BQQM 2J83A 4GQLA 4H49A 2OW9A 2YB9A 4PKSA 1WNIA 4GF1A 1FM1A 2JNPA 1IAEA 2RJPA 2K9CA 1G49A 2WO8A 3LK8A 4WKIA 4FXQA 3EHXA 1UMSA 3Q2HA 2SRTA 5JMYA 4GUYA 3EDHA 2WO9A 2JT5A 3F1AA 1Q3AA 2HU6A 1BKCA 3DPFA 4XCTA 3OHOA 2OW2A 3KEJA 4L19A 4G0DA 4A7BA 830CA 3KEKA 1D5JA 4DPEA 3DNGA 1ND1A 3NX7A 2X3AA 3WV3A 1UTTA 3TS4A 1J7NA 1I73A 1K7IA 4FXYP 5I0LA 2JT6A 3AIGA 1B3DA 4I35A 1OMJA 1BQOA 4JPAA 2Y6DA 4WKEA 3RTSA 1FLSA 1O0QA 3CKIA 1D7XA 3HDAP 4GWMA 4HMAA 1JJ9A 4Q1LA 966CA 4AXQA 3EHYA 3K7LA 3DTKA 5CXAA 3KWVC 1UMTA 4A3WA 1JIWP 2YUFA 2JIHA 5CZMA 1KUFA 3LQ0A 3GBOA 1GO7P 1IADA 1RM8A 4FU4A 1YCMA 2E2DA 3L0TA 4XBHA 1BKCE 4PKQA 4AIGA 1BKCI 1D8MA 3DL1A 3AYKA 1I1IP 1XFXA 1EUBA 3LUMA 456CA 3F15A 3HDBA 5D2BA 1AYKA 1DMTA 1C8TA 4XM6A 3I7IA 2MZIA 1QJJA 3HY9A 4GR8A 1XURA 3L0VA 2W14A 2OW1A 2DW1A 1RMZA 1YOUA 3LGPA 3LJTA 3BA0A 4PKWA 4ILWD 4HX3A 2PJTA 3I7GA 2OVXA 4H30A 1O0TA 5I3MA 2AYKA 3LJZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HFC A;  1JKY A;  1ROS A;  2O3E A;  3U1R A;  1XFZ A;  1R54 A;  4GWN A;  3SHI A;  2W0D A;  3E8R A;  1K7Q A;  4H84 A;  4XM7 A;  1PWW A;  1XFU A;  1SU3 A;  1EB6 A;  4GR0 A;  1CXV A;  2D1N A;  2MLS A;  1BM6 A;  4EFS A;  2X7M A;  3HY7 A;  1OO9 A;  2ERQ A;  1L6J A;  1CGE A;  2ERO A;  1BUV M;  1CGL A;  2O36 A;  1Y93 A;  2DDY A;  2J0T A;  1ZTQ A;  2Z2D A;  3EDG A;  3KME A;  1KUH A;  2K2G A;  5BOT A;  4PKR A;  1A86 A;  1XUC A;  1H71 P;  1SMP A;  1SAT A;  1GO8 P;  1GKD A;  2OY2 A;  4PKT A;  1UTZ A;  1JAO A;  5H8X A;  4H1Q A;  3LJG A;  1HTD A;  3O64 A;  2MZH A;  3VI1 A;  1GKC A;  1ZXC A;  2X3C A;  1R1J A;  2N8R A;  2JSD A;  4JQG A;  3ZVS A;  2KRJ A;  3HB2 P;  5BPA A;  4PKV A;  3LMC A;  4PKU A;  2POJ A;  4GR3 A;  5D3C A;  2MLR A;  3F16 A;  2OXZ A;  1ATL A;  1KAP P;  4H82 A;  3DWB A;  1JAQ A;  1I76 A;  3V96 B;  1OM8 A;  2FV5 A;  4JP4 A;  4WF6 A;  1CIZ A;  1AKL A;  3B8Z A;  2WOA A;  3EDZ A;  1PWQ A;  2OZR A;  4IN9 A;  1SRP A;  5L79 A;  2A8H A;  4DV8 A;  1ZXV A;  1MMR A;  4ZR5 A;  4WZV A;  1G05 A;  5D1U A;  3LEA A;  5D7W A;  2MZE A;  1QIC A;  1MMB A;  1DTH A;  3ELM A;  5I2Z A;  2L0R A;  1BIW A;  5BOY A;  1A85 A;  1CGF A;  2TCL A;  1MNC A;  3F19 A;  3ZXH A;  5L7F A;  2RJQ A;  2CKI A;  1MMQ A;  1GE5 A;  3HYG A;  3HBV P;  3N2V A;  3LIL A;  2X3B A;  1JIZ A;  4AYK A;  1B8Y A;  3O2X A;  1JAP A;  1HV5 A;  1EAK A;  1CK7 A;  1XFV A;  3TSK A;  3WV2 A;  2YIG A;  1AST A;  1KUG A;  3USN A;  5B5O A;  1HFS A;  4CTH A;  3UVC A;  2AIG P;  1KUI A;  1G12 A;  4QKZ A;  3N2U A;  4AUO A;  1CAQ A;  3DSL A;  2USN A;  1BSW A;  3LE9 A;  2OVZ A;  1C3I A;  1OS9 A;  3TT4 A;  3DPE A;  1KUK A;  1Z3J A;  4L63 A;  1SLM A;  1IAA A;  2OW0 A;  4G9L A;  1XUD A;  3HBU P;  1GE7 A;  4JIJ A;  1PWP A;  1MMP A;  1QJI A;  1OS2 A;  4I03 A;  3LIR A;  3TVC A;  5B5P A;  1R1H A;  4IJO A;  3OHL A;  3EDI A;  3P24 A;  1OM7 A;  1USN A;  4H76 A;  3B92 A;  3EWJ A;  1ZP5 A;  3LUN A;  1HY7 A;  2CLT A;  5D1T A;  1KBC A;  4ON1 A;  4DF9 A;  4DD8 A;  5D1S A;  3F18 A;  5I43 A;  3G42 A;  3KRY A;  1PWV A;  4L6T A;  3KHI A;  1AF0 A;  3LIK A;  3KEC A;  3RTT A;  3KMC A;  4XM8 A;  5CUH A;  1CQR A;  1FBL A;  1GXD A;  1BUD A;  1D8F A;  1YQY A;  1OM6 A;  1G9K A;  1JK3 A;  3Q2G A;  2FV9 A;  2OI0 A;  1XFY A;  2QPJ A;  1ZS0 A;  3K7N A;  1UEA A;  2I47 A;  3P1V A;  1Y0V A;  1JH1 A;  4JA1 A;  3G5C A;  1R1I A;  5I12 A;  1IAB A;  3B2Z A;  1QUA A;  2ERP A;  4H2E A;  1QIA A;  2OXW A;  4H3X A;  3WV1 A;  3MA2 A;  2XS4 A;  5LAB A;  3LKA A;  2D1O A;  4IUW A;  2W15 A;  1IAG A;  1G4K A;  1S4B P;  1XFW A;  3ZUK A;  1GE6 A;  1PWU A;  1QIB A;  4FVL A;  1YP1 A;  1IAC A;  1R55 A;  4J4M A;  1HOV A;  2OY4 A;  1SLN A;  2V4B A;  3VTG A;  1BZS A;  1JAN A;  2DW2 A;  3AYU A;  4R3V A;  2XS3 A;  2W13 A;  2DDF A;  3F17 A;  1K7G A;  3LQB A;  2W12 A;  1ZVX A;  4WK7 A;  1C7K A;  2DW0 A;  2OXU A;  2Y6C A;  5I4O A;  1Y8J A;  2E3X A;  1BQQ M;  2J83 A;  4GQL A;  4H49 A;  2OW9 A;  2YB9 A;  4PKS A;  1WNI A;  4GF1 A;  1FM1 A;  2JNP A;  1IAE A;  2RJP A;  2K9C A;  1G49 A;  2WO8 A;  3LK8 A;  4WKI A;  4FXQ A;  3EHX A;  1UMS A;  3Q2H A;  2SRT A;  5JMY A;  4GUY A;  3EDH A;  2WO9 A;  2JT5 A;  3F1A A;  1Q3A A;  2HU6 A;  1BKC A;  3DPF A;  4XCT A;  3OHO A;  2OW2 A;  3KEJ A;  4L19 A;  4G0D A;  4A7B A;  830C A;  3KEK A;  1D5J A;  4DPE A;  3DNG A;  1ND1 A;  3NX7 A;  2X3A A;  3WV3 A;  1UTT A;  3TS4 A;  1J7N A;  1I73 A;  1K7I A;  4FXY P;  5I0L A;  2JT6 A;  3AIG A;  1B3D A;  4I35 A;  1OMJ A;  1BQO A;  4JPA A;  2Y6D A;  4WKE A;  3RTS A;  1FLS A;  1O0Q A;  3CKI A;  1D7X A;  3HDA P;  4GWM A;  4HMA A;  1JJ9 A;  4Q1L A;  966C A;  4AXQ A;  3EHY A;  3K7L A;  5CXA A;  3KWV C;  1UMT A;  4A3W A;  1JIW P;  2JIH A;  5CZM A;  1KUF A;  3LQ0 A;  3GBO A;  1GO7 P;  1IAD A;  1RM8 A;  4FU4 A;  1YCM A;  2E2D A;  3L0T A;  4XBH A;  1BKC E;  4PKQ A;  4AIG A;  1BKC I;  1D8M A;  3DL1 A;  3AYK A;  1I1I P;  1XFX A;  1EUB A;  3LUM A;  456C A;  3F15 A;  3HDB A;  5D2B A;  1AYK A;  1DMT A;  1C8T A;  4XM6 A;  3I7I A;  2MZI A;  1QJJ A;  3HY9 A;  4GR8 A;  1XUR A;  3L0V A;  2W14 A;  2OW1 A;  2DW1 A;  1RMZ A;  1YOU A;  3LGP A;  3LJT A;  3BA0 A;  4PKW A;  4ILW D;  4HX3 A;  2PJT A;  3I7G A;  2OVX A;  4H30 A;  1O0T A;  5I3M A;  2AYK A;  3LJZ A; 
#chains in the Genus database with same CATH topology
 1HFC A;  1JKY A;  1ROS A;  2O3E A;  3U1R A;  1XFZ A;  1R54 A;  4GWN A;  3SHI A;  2W0D A;  3E8R A;  1K7Q A;  4H84 A;  4XM7 A;  1PWW A;  1XFU A;  1SU3 A;  1EB6 A;  4GR0 A;  1CXV A;  2D1N A;  2MLS A;  1BM6 A;  4EFS A;  2X7M A;  3HY7 A;  1OO9 A;  2ERQ A;  4L7A A;  1L6J A;  1CGE A;  2ERO A;  1BUV M;  1CGL A;  2O36 A;  1Y93 A;  2DDY A;  2J0T A;  1ZTQ A;  2Z2D A;  3EDG A;  3KME A;  1KUH A;  2K2G A;  5BOT A;  4PKR A;  1A86 A;  3DTI A;  1XUC A;  1XM5 A;  1H71 P;  1SMP A;  1SAT A;  1GO8 P;  1GKD A;  2OY2 A;  4PKT A;  1UTZ A;  1JAO A;  5H8X A;  4H1Q A;  3LJG A;  1HTD A;  3O64 A;  2MZH A;  3VI1 A;  1GKC A;  1ZXC A;  2X3C A;  1R1J A;  2N8R A;  2JSD A;  4JQG A;  3ZVS A;  2KRJ A;  3HB2 P;  5BPA A;  4PKV A;  3LMC A;  4PKU A;  2POJ A;  4GR3 A;  5D3C A;  2MLR A;  3F16 A;  2OXZ A;  1ATL A;  1KAP P;  4H82 A;  3DWB A;  1JAQ A;  1I76 A;  3V96 B;  1OM8 A;  2FV5 A;  4JP4 A;  4WF6 A;  1CIZ A;  1AKL A;  3B8Z A;  2WOA A;  3EDZ A;  1PWQ A;  2OZR A;  4IN9 A;  1SRP A;  5L79 A;  2A8H A;  4DV8 A;  1ZXV A;  1MMR A;  4ZR5 A;  4WZV A;  1G05 A;  5D1U A;  3LEA A;  5D7W A;  2MZE A;  1QIC A;  1MMB A;  1DTH A;  3ELM A;  5I2Z A;  2L0R A;  1BIW A;  5BOY A;  1A85 A;  1CGF A;  2TCL A;  1MNC A;  3F19 A;  3ZXH A;  5L7F A;  2RJQ A;  2CKI A;  1MMQ A;  1GE5 A;  3HYG A;  3HBV P;  3N2V A;  3LIL A;  2X3B A;  1JIZ A;  4AYK A;  1B8Y A;  3O2X A;  1JAP A;  1HV5 A;  1EAK A;  1CK7 A;  1XFV A;  3TSK A;  3WV2 A;  2YIG A;  1AST A;  1KUG A;  1TVI A;  3USN A;  5B5O A;  1HFS A;  4CTH A;  3UVC A;  2AIG P;  1KUI A;  3DTE A;  1G12 A;  4QKZ A;  3N2U A;  4AUO A;  1CAQ A;  3DSL A;  2USN A;  1BSW A;  3LE9 A;  2OVZ A;  1C3I A;  1OS9 A;  3TT4 A;  3DPE A;  1KUK A;  1Z3J A;  4L63 A;  1SLM A;  1IAA A;  2OW0 A;  4G9L A;  1XUD A;  3HBU P;  1GE7 A;  4JIJ A;  1PWP A;  1MMP A;  1QJI A;  1OS2 A;  4I03 A;  3LIR A;  3TVC A;  5B5P A;  1R1H A;  4IJO A;  3OHL A;  3EDI A;  3P24 A;  1OM7 A;  1USN A;  4H76 A;  3B92 A;  3EWJ A;  1ZP5 A;  3LUN A;  1HY7 A;  2CLT A;  5D1T A;  1KBC A;  4ON1 A;  4DF9 A;  4DD8 A;  5D1S A;  3F18 A;  5I43 A;  3G42 A;  3KRY A;  1PWV A;  4L6T A;  3KHI A;  1AF0 A;  3LIK A;  3KEC A;  3RTT A;  3KMC A;  4XM8 A;  5CUH A;  1CQR A;  1FBL A;  1GXD A;  1BUD A;  1D8F A;  1YQY A;  1OM6 A;  1G9K A;  1JK3 A;  3Q2G A;  2FV9 A;  2OI0 A;  1XFY A;  2QPJ A;  1ZS0 A;  3K7N A;  1UEA A;  2I47 A;  3P1V A;  1Y0V A;  1JH1 A;  4JA1 A;  3G5C A;  1R1I A;  5I12 A;  1IAB A;  3B2Z A;  1QUA A;  2ERP A;  4H2E A;  1QIA A;  2OXW A;  4H3X A;  3WV1 A;  3MA2 A;  2XS4 A;  5LAB A;  3LKA A;  2D1O A;  4IUW A;  2W15 A;  1IAG A;  1G4K A;  1S4B P;  1XFW A;  3ZUK A;  1GE6 A;  1PWU A;  1QIB A;  4FVL A;  1YP1 A;  1IAC A;  1R55 A;  4J4M A;  1HOV A;  2OY4 A;  1SLN A;  2V4B A;  3VTG A;  1BZS A;  1JAN A;  2DW2 A;  3AYU A;  4R3V A;  2XS3 A;  2W13 A;  2DDF A;  3F17 A;  1K7G A;  3LQB A;  2W12 A;  1ZVX A;  4WK7 A;  1C7K A;  2DW0 A;  2OXU A;  2Y6C A;  5I4O A;  1Y8J A;  2E3X A;  1BQQ M;  2J83 A;  4GQL A;  4H49 A;  2OW9 A;  2YB9 A;  4PKS A;  1WNI A;  4GF1 A;  1FM1 A;  2JNP A;  1IAE A;  2RJP A;  2K9C A;  1G49 A;  2WO8 A;  3LK8 A;  4WKI A;  4FXQ A;  3EHX A;  1UMS A;  3Q2H A;  2SRT A;  5JMY A;  4GUY A;  3EDH A;  2WO9 A;  2JT5 A;  3F1A A;  1Q3A A;  2HU6 A;  1BKC A;  3DPF A;  4XCT A;  3OHO A;  2OW2 A;  3KEJ A;  4L19 A;  4G0D A;  4A7B A;  830C A;  3KEK A;  1D5J A;  4DPE A;  3DNG A;  1ND1 A;  3NX7 A;  2X3A A;  3WV3 A;  1UTT A;  3TS4 A;  1J7N A;  1I73 A;  1K7I A;  4FXY P;  5I0L A;  2JT6 A;  3AIG A;  1B3D A;  1XAX A;  4I35 A;  1OMJ A;  1BQO A;  4JPA A;  2Y6D A;  4WKE A;  3RTS A;  1FLS A;  1O0Q A;  3CKI A;  1D7X A;  3HDA P;  4GWM A;  4HMA A;  1JJ9 A;  4Q1L A;  966C A;  4AXQ A;  3EHY A;  3K7L A;  3DTK A;  5CXA A;  3KWV C;  1UMT A;  4A3W A;  1JIW P;  2YUF A;  2JIH A;  5CZM A;  1KUF A;  3LQ0 A;  3GBO A;  1GO7 P;  1IAD A;  1RM8 A;  4FU4 A;  1YCM A;  2E2D A;  3L0T A;  4XBH A;  1BKC E;  4PKQ A;  4AIG A;  1BKC I;  1D8M A;  3DL1 A;  3AYK A;  1I1I P;  1XFX A;  1EUB A;  3LUM A;  456C A;  3F15 A;  3HDB A;  5D2B A;  1AYK A;  1DMT A;  1C8T A;  4XM6 A;  3I7I A;  2MZI A;  1QJJ A;  3HY9 A;  4GR8 A;  1XUR A;  3L0V A;  2W14 A;  2OW1 A;  2DW1 A;  1RMZ A;  1YOU A;  3LGP A;  3LJT A;  3BA0 A;  4PKW A;  4ILW D;  4HX3 A;  2PJT A;  3I7G A;  2OVX A;  4H30 A;  1O0T A;  5I3M A;  2AYK A;  1OZ9 A;  3LJZ A; 
#chains in the Genus database with same CATH homology
 1HFC A;  1JKY A;  1ROS A;  2O3E A;  3U1R A;  1XFZ A;  1R54 A;  4GWN A;  3SHI A;  2W0D A;  3E8R A;  1K7Q A;  4H84 A;  4XM7 A;  1PWW A;  1XFU A;  1SU3 A;  1EB6 A;  4GR0 A;  1CXV A;  2D1N A;  2MLS A;  1BM6 A;  4EFS A;  2X7M A;  3HY7 A;  1OO9 A;  2ERQ A;  4L7A A;  1L6J A;  1CGE A;  2ERO A;  1BUV M;  1CGL A;  2O36 A;  1Y93 A;  2DDY A;  2J0T A;  1ZTQ A;  2Z2D A;  3EDG A;  3KME A;  1KUH A;  2K2G A;  5BOT A;  4PKR A;  1A86 A;  3DTI A;  1XUC A;  1H71 P;  1SMP A;  1SAT A;  1GO8 P;  1GKD A;  2OY2 A;  4PKT A;  1UTZ A;  1JAO A;  5H8X A;  4H1Q A;  3LJG A;  1HTD A;  3O64 A;  2MZH A;  3VI1 A;  1GKC A;  1ZXC A;  2X3C A;  1R1J A;  2N8R A;  2JSD A;  4JQG A;  3ZVS A;  2KRJ A;  3HB2 P;  5BPA A;  4PKV A;  3LMC A;  4PKU A;  2POJ A;  4GR3 A;  5D3C A;  2MLR A;  3F16 A;  2OXZ A;  1ATL A;  1KAP P;  4H82 A;  3DWB A;  1JAQ A;  1I76 A;  3V96 B;  1OM8 A;  2FV5 A;  4JP4 A;  4WF6 A;  1CIZ A;  1AKL A;  3B8Z A;  2WOA A;  3EDZ A;  1PWQ A;  2OZR A;  4IN9 A;  1SRP A;  5L79 A;  2A8H A;  4DV8 A;  1ZXV A;  1MMR A;  4ZR5 A;  4WZV A;  1G05 A;  5D1U A;  3LEA A;  5D7W A;  2MZE A;  1QIC A;  1MMB A;  1DTH A;  3ELM A;  5I2Z A;  2L0R A;  1BIW A;  5BOY A;  1A85 A;  1CGF A;  2TCL A;  1MNC A;  3F19 A;  3ZXH A;  5L7F A;  2RJQ A;  2CKI A;  1MMQ A;  1GE5 A;  3HYG A;  3HBV P;  3N2V A;  3LIL A;  2X3B A;  1JIZ A;  4AYK A;  1B8Y A;  3O2X A;  1JAP A;  1HV5 A;  1EAK A;  1CK7 A;  1XFV A;  3TSK A;  3WV2 A;  2YIG A;  1AST A;  1KUG A;  3USN A;  5B5O A;  1HFS A;  4CTH A;  3UVC A;  2AIG P;  1KUI A;  3DTE A;  1G12 A;  4QKZ A;  3N2U A;  4AUO A;  1CAQ A;  3DSL A;  2USN A;  1BSW A;  3LE9 A;  2OVZ A;  1C3I A;  1OS9 A;  3TT4 A;  3DPE A;  1KUK A;  1Z3J A;  4L63 A;  1SLM A;  1IAA A;  2OW0 A;  4G9L A;  1XUD A;  3HBU P;  1GE7 A;  4JIJ A;  1PWP A;  1MMP A;  1QJI A;  1OS2 A;  4I03 A;  3LIR A;  3TVC A;  5B5P A;  1R1H A;  4IJO A;  3OHL A;  3EDI A;  3P24 A;  1OM7 A;  1USN A;  4H76 A;  3B92 A;  3EWJ A;  1ZP5 A;  3LUN A;  1HY7 A;  2CLT A;  5D1T A;  1KBC A;  4ON1 A;  4DF9 A;  4DD8 A;  5D1S A;  3F18 A;  5I43 A;  3G42 A;  3KRY A;  1PWV A;  4L6T A;  3KHI A;  1AF0 A;  3LIK A;  3KEC A;  3RTT A;  3KMC A;  4XM8 A;  5CUH A;  1CQR A;  1FBL A;  1GXD A;  1BUD A;  1D8F A;  1YQY A;  1OM6 A;  1G9K A;  1JK3 A;  3Q2G A;  2FV9 A;  2OI0 A;  1XFY A;  2QPJ A;  1ZS0 A;  3K7N A;  1UEA A;  2I47 A;  3P1V A;  1Y0V A;  1JH1 A;  4JA1 A;  3G5C A;  1R1I A;  5I12 A;  1IAB A;  3B2Z A;  1QUA A;  2ERP A;  4H2E A;  1QIA A;  2OXW A;  4H3X A;  3WV1 A;  3MA2 A;  2XS4 A;  5LAB A;  3LKA A;  2D1O A;  4IUW A;  2W15 A;  1IAG A;  1G4K A;  1S4B P;  1XFW A;  3ZUK A;  1GE6 A;  1PWU A;  1QIB A;  4FVL A;  1YP1 A;  1IAC A;  1R55 A;  4J4M A;  1HOV A;  2OY4 A;  1SLN A;  2V4B A;  3VTG A;  1BZS A;  1JAN A;  2DW2 A;  3AYU A;  4R3V A;  2XS3 A;  2W13 A;  2DDF A;  3F17 A;  1K7G A;  3LQB A;  2W12 A;  1ZVX A;  4WK7 A;  1C7K A;  2DW0 A;  2OXU A;  2Y6C A;  5I4O A;  1Y8J A;  2E3X A;  1BQQ M;  2J83 A;  4GQL A;  4H49 A;  2OW9 A;  2YB9 A;  4PKS A;  1WNI A;  4GF1 A;  1FM1 A;  2JNP A;  1IAE A;  2RJP A;  2K9C A;  1G49 A;  2WO8 A;  3LK8 A;  4WKI A;  4FXQ A;  3EHX A;  1UMS A;  3Q2H A;  2SRT A;  5JMY A;  4GUY A;  3EDH A;  2WO9 A;  2JT5 A;  3F1A A;  1Q3A A;  2HU6 A;  1BKC A;  3DPF A;  4XCT A;  3OHO A;  2OW2 A;  3KEJ A;  4L19 A;  4G0D A;  4A7B A;  830C A;  3KEK A;  1D5J A;  4DPE A;  3DNG A;  1ND1 A;  3NX7 A;  2X3A A;  3WV3 A;  1UTT A;  3TS4 A;  1J7N A;  1I73 A;  1K7I A;  4FXY P;  5I0L A;  2JT6 A;  3AIG A;  1B3D A;  4I35 A;  1OMJ A;  1BQO A;  4JPA A;  2Y6D A;  4WKE A;  3RTS A;  1FLS A;  1O0Q A;  3CKI A;  1D7X A;  3HDA P;  4GWM A;  4HMA A;  1JJ9 A;  4Q1L A;  966C A;  4AXQ A;  3EHY A;  3K7L A;  3DTK A;  5CXA A;  3KWV C;  1UMT A;  4A3W A;  1JIW P;  2YUF A;  2JIH A;  5CZM A;  1KUF A;  3LQ0 A;  3GBO A;  1GO7 P;  1IAD A;  1RM8 A;  4FU4 A;  1YCM A;  2E2D A;  3L0T A;  4XBH A;  1BKC E;  4PKQ A;  4AIG A;  1BKC I;  1D8M A;  3DL1 A;  3AYK A;  1I1I P;  1XFX A;  1EUB A;  3LUM A;  456C A;  3F15 A;  3HDB A;  5D2B A;  1AYK A;  1DMT A;  1C8T A;  4XM6 A;  3I7I A;  2MZI A;  1QJJ A;  3HY9 A;  4GR8 A;  1XUR A;  3L0V A;  2W14 A;  2OW1 A;  2DW1 A;  1RMZ A;  1YOU A;  3LGP A;  3LJT A;  3BA0 A;  4PKW A;  4ILW D;  4HX3 A;  2PJT A;  3I7G A;  2OVX A;  4H30 A;  1O0T A;  5I3M A;  2AYK A;  3LJZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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