4EKDB

Structure of human regulator of g protein signaling 2 (rgs2) in complex with murine galpha-q(r183c)
Total Genus 43
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
132
structure length
132
Chain Sequence
FGSPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Signaling protein/inhibitor
molecule keywords Guanine nucleotide-binding protein G(q) subunit alpha
publication title Structural and functional analysis of the regulator of G protein signaling 2-g alpha q complex.
pubmed doi rcsb
source organism Mus musculus
total genus 43
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2012-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 4ekdB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 4ekdB01
3PVUA 4MK0A 5HE0A 1EZYA 5HE1A 2IHBB 3KRXA 3PSCA 2JNUA 1EMUA 2AF0A 1EZTA 2OJ4A 1AGRE 2OWIA 2D9JA 2BT2A 5DO9B 2IHDA 4TNBA 1CMZA 1DK8A 2V4ZB 3PVWA 2JM5A 2BCJA 2DLVA 5HE3A 1OMWA 3C7KB 3NYNA 4TNDA 3CIKA 5HE2A 1FQKB 1FQJB 2ODEB 1FQIA 2GTPC 3V5WA 4PNKA 4EKDB 3KRWA 3NYOA 2EBZA 2CRPA 3UZTA 3C7LA 2IK8B 2BV1A
chains in the Genus database with same CATH superfamily
3PVUA 4MK0A 5REQB 5HE0A 1EZYA 5HE1A 2IHBB 3KRXA 3PSCA 2JNUA 1EMUA 2AF0A 1EZTA 2OJ4A 1AGRE 2OWIA 2D9JA 2BT2A 5DO9B 2IHDA 4TNBA 1CMZA 1DK8A 2V4ZB 3I5QA 3PVWA 2JM5A 4HTEA 2BCJA 2DLVA 5HE3A 3QYFA 1OMWA 3C7KB 3NYNA 4TNDA 3CIKA 5HE2A 1FQKB 1FQJB 2ODEB 1FQIA 2GTPC 3V5WA 4PNKA 4EKDB 3KRWA 3NYOA 2EBZA 2CRPA 3UZTA 3C7LA 2IK8B 2BV1A
chains in the Genus database with same CATH topology
3PVUA 4MK0A 5REQB 5HE0A 1EZYA 5HE1A 2IHBB 3KRXA 3PSCA 2JNUA 1EMUA 2AF0A 1EZTA 2OJ4A 1AGRE 2OWIA 2D9JA 2BT2A 5DO9B 2IHDA 4TNBA 1CMZA 1DK8A 2V4ZB 3PVWA 2JM5A 2BCJA 2DLVA 5HE3A 3QYFA 1OMWA 3C7KB 3NYNA 4TNDA 3CIKA 5HE2A 1FQKB 1FQJB 2ODEB 1FQIA 2GTPC 3V5WA 4PNKA 4EKDB 3KRWA 3NYOA 2EBZA 2CRPA 3UZTA 3C7LA 2IK8B 2BV1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PVU A;  4MK0 A;  5HE0 A;  1EZY A;  5HE1 A;  2IHB B;  3KRX A;  3PSC A;  2JNU A;  1EMU A;  2AF0 A;  1EZT A;  2OJ4 A;  1AGR E;  2OWI A;  2D9J A;  2BT2 A;  5DO9 B;  2IHD A;  4TNB A;  1CMZ A;  1DK8 A;  2V4Z B;  3PVW A;  2JM5 A;  2BCJ A;  2DLV A;  5HE3 A;  1OMW A;  3C7K B;  3NYN A;  4TND A;  3CIK A;  5HE2 A;  1FQK B;  1FQJ B;  2ODE B;  1FQI A;  2GTP C;  3V5W A;  4PNK A;  4EKD B;  3KRW A;  3NYO A;  2EBZ A;  2CRP A;  3UZT A;  3C7L A;  2IK8 B;  2BV1 A; 
#chains in the Genus database with same CATH topology
 3PVU A;  4MK0 A;  5REQ B;  5HE0 A;  1EZY A;  5HE1 A;  2IHB B;  3KRX A;  3PSC A;  2JNU A;  1EMU A;  2AF0 A;  1EZT A;  2OJ4 A;  1AGR E;  2OWI A;  2D9J A;  2BT2 A;  5DO9 B;  2IHD A;  4TNB A;  1CMZ A;  1DK8 A;  2V4Z B;  3I5Q A;  3PVW A;  2JM5 A;  4HTE A;  2BCJ A;  2DLV A;  5HE3 A;  3QYF A;  1OMW A;  3C7K B;  3NYN A;  4TND A;  3CIK A;  5HE2 A;  1FQK B;  1FQJ B;  2ODE B;  1FQI A;  2GTP C;  3V5W A;  4PNK A;  4EKD B;  3KRW A;  3NYO A;  2EBZ A;  2CRP A;  3UZT A;  3C7L A;  2IK8 B;  2BV1 A; 
#chains in the Genus database with same CATH homology
 3PVU A;  4MK0 A;  5REQ B;  5HE0 A;  1EZY A;  5HE1 A;  2IHB B;  3KRX A;  3PSC A;  2JNU A;  1EMU A;  2AF0 A;  1EZT A;  2OJ4 A;  1AGR E;  2OWI A;  2D9J A;  2BT2 A;  5DO9 B;  2IHD A;  4TNB A;  1CMZ A;  1DK8 A;  2V4Z B;  3PVW A;  2JM5 A;  2BCJ A;  2DLV A;  5HE3 A;  3QYF A;  1OMW A;  3C7K B;  3NYN A;  4TND A;  3CIK A;  5HE2 A;  1FQK B;  1FQJ B;  2ODE B;  1FQI A;  2GTP C;  3V5W A;  4PNK A;  4EKD B;  3KRW A;  3NYO A;  2EBZ A;  2CRP A;  3UZT A;  3C7L A;  2IK8 B;  2BV1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...