4EKDB

Structure of human regulator of g protein signaling 2 (rgs2) in complex with murine galpha-q(r183c)
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
132
structure length
132
Chain Sequence
FGSPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional analysis of the regulator of G protein signaling 2-g alpha q complex.
pubmed doi rcsb
molecule tags Signaling protein/inhibitor
source organism Mus musculus
molecule keywords Guanine nucleotide-binding protein G(q) subunit alpha
total genus 43
structure length 132
sequence length 132
ec nomenclature
pdb deposition date 2012-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00615 RGS Regulator of G protein signaling domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.167.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 2 Regulator of G-protein Signalling 4, domain 2 4ekdB02
1.10.196.10 Mainly Alpha Orthogonal Bundle Regulator of G-protein Signalling 4; domain 1 Regulator of G-protein Signalling 4; domain 1 4ekdB01
2DLVA 5HE3A 4MK0A 3KRXA 3NYNA 2CRPA 3KRWA 5HE2A 2EBZA 3C7KB 3UZTA 2BV1A 1FQIA 3PVWA 1EZYA 2BCJA 2OWIA 4TNBA 2JNUA 2D9JA 2OJ4A 2JM5A 2ODEB 3PVUA 4PNKA 3NYOA 3C7LA 5HE0A 5HE1A 3V5WA 3CIKA 1EZTA 2BT2A 1EMUA 4TNDA 2IHDA 1OMWA 1AGRE 2GTPC 4EKDB 1FQKB 2IK8B 5DO9B 1FQJB 1CMZA 2V4ZB 2AF0A 1DK8A 3PSCA 2IHBB
chains in the Genus database with same CATH superfamily
2DLVA 5HE3A 4MK0A 3KRXA 3NYNA 2CRPA 3KRWA 5HE2A 2EBZA 3C7KB 3UZTA 2BV1A 1FQIA 3PVWA 1EZYA 2BCJA 2OWIA 4TNBA 3QYFA 2JNUA 2D9JA 2OJ4A 2JM5A 2ODEB 3PVUA 4PNKA 3NYOA 3C7LA 5HE0A 5REQB 5HE1A 3V5WA 3CIKA 1EZTA 2BT2A 1EMUA 4TNDA 2IHDA 1OMWA 1AGRE 2GTPC 4EKDB 1FQKB 2IK8B 5DO9B 1FQJB 3I5QA 1CMZA 2V4ZB 4HTEA 2AF0A 1DK8A 3PSCA 2IHBB
chains in the Genus database with same CATH topology
2DLVA 5HE3A 4MK0A 3KRXA 3NYNA 2CRPA 3KRWA 5HE2A 2EBZA 3C7KB 3UZTA 2BV1A 1FQIA 3PVWA 1EZYA 2BCJA 2OWIA 4TNBA 3QYFA 2JNUA 2D9JA 2OJ4A 2JM5A 2ODEB 3PVUA 4PNKA 3NYOA 3C7LA 5HE0A 5REQB 5HE1A 3V5WA 3CIKA 1EZTA 2BT2A 1EMUA 4TNDA 2IHDA 1OMWA 1AGRE 2GTPC 4EKDB 1FQKB 2IK8B 5DO9B 1FQJB 1CMZA 2V4ZB 2AF0A 1DK8A 3PSCA 2IHBB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DLV A;  5HE3 A;  4MK0 A;  3KRX A;  3NYN A;  2CRP A;  3KRW A;  5HE2 A;  2EBZ A;  3C7K B;  3UZT A;  2BV1 A;  1FQI A;  3PVW A;  1EZY A;  2BCJ A;  2OWI A;  4TNB A;  2JNU A;  2D9J A;  2OJ4 A;  2JM5 A;  2ODE B;  3PVU A;  4PNK A;  3NYO A;  3C7L A;  5HE0 A;  5HE1 A;  3V5W A;  3CIK A;  1EZT A;  2BT2 A;  1EMU A;  4TND A;  2IHD A;  1OMW A;  1AGR E;  2GTP C;  4EKD B;  1FQK B;  2IK8 B;  5DO9 B;  1FQJ B;  1CMZ A;  2V4Z B;  2AF0 A;  1DK8 A;  3PSC A;  2IHB B; 
#chains in the Genus database with same CATH topology
 2DLV A;  5HE3 A;  4MK0 A;  3KRX A;  3NYN A;  2CRP A;  3KRW A;  5HE2 A;  2EBZ A;  3C7K B;  3UZT A;  2BV1 A;  1FQI A;  3PVW A;  1EZY A;  2BCJ A;  2OWI A;  4TNB A;  3QYF A;  2JNU A;  2D9J A;  2OJ4 A;  2JM5 A;  2ODE B;  3PVU A;  4PNK A;  3NYO A;  3C7L A;  5HE0 A;  5REQ B;  5HE1 A;  3V5W A;  3CIK A;  1EZT A;  2BT2 A;  1EMU A;  4TND A;  2IHD A;  1OMW A;  1AGR E;  2GTP C;  4EKD B;  1FQK B;  2IK8 B;  5DO9 B;  1FQJ B;  3I5Q A;  1CMZ A;  2V4Z B;  4HTE A;  2AF0 A;  1DK8 A;  3PSC A;  2IHB B; 
#chains in the Genus database with same CATH homology
 2DLV A;  5HE3 A;  4MK0 A;  3KRX A;  3NYN A;  2CRP A;  3KRW A;  5HE2 A;  2EBZ A;  3C7K B;  3UZT A;  2BV1 A;  1FQI A;  3PVW A;  1EZY A;  2BCJ A;  2OWI A;  4TNB A;  3QYF A;  2JNU A;  2D9J A;  2OJ4 A;  2JM5 A;  2ODE B;  3PVU A;  4PNK A;  3NYO A;  3C7L A;  5HE0 A;  5REQ B;  5HE1 A;  3V5W A;  3CIK A;  1EZT A;  2BT2 A;  1EMU A;  4TND A;  2IHD A;  1OMW A;  1AGR E;  2GTP C;  4EKD B;  1FQK B;  2IK8 B;  5DO9 B;  1FQJ B;  1CMZ A;  2V4Z B;  2AF0 A;  1DK8 A;  3PSC A;  2IHB B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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