4ERSA

A molecular basis for negative regulation of the glucagon receptor
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
96
structure length
96
Chain Sequence
VMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords Fab light chain
publication title Molecular basis for negative regulation of the glucagon receptor.
pubmed doi rcsb
source organism Homo sapiens
total genus 23
structure length 96
sequence length 96
ec nomenclature
pdb deposition date 2012-04-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.1240.10 Few Secondary Structures Irregular Hormone receptor fold GPCR, family 2, extracellular hormone receptor domain 4ersA00
3H3GA 3C59A 3N7PA 2QKHA 3AQFB 4DLOA 2JNDA 2JODA 2JNCA 3IOLA 4HJ0A 1U34A 3N7RA 3EHTA 2L27A 3EHSA 2XDGA 3N7SA 4DLQA 3C5TA 4LF3C 3EHUA 5II0A 4ZGMA 3C4MA 3L2JA 4ERSA
chains in the Genus database with same CATH superfamily
3H3GA 3C59A 3N7PA 2QKHA 3AQFB 4DLOA 2JNDA 2JODA 2JNCA 3IOLA 4HJ0A 1U34A 3N7RA 3EHTA 2L27A 3EHSA 2XDGA 3N7SA 4DLQA 3C5TA 4LF3C 3EHUA 5II0A 4ZGMA 3C4MA 3L2JA 4ERSA
chains in the Genus database with same CATH topology
3H3GA 3C59A 3N7PA 2QKHA 3AQFB 4DLOA 2JNDA 2JODA 2JNCA 3IOLA 4HJ0A 1U34A 3N7RA 3EHTA 2L27A 3EHSA 2XDGA 3N7SA 4DLQA 3C5TA 4LF3C 3EHUA 5II0A 4ZGMA 3C4MA 3L2JA 4ERSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H3G A;  3C59 A;  3N7P A;  2QKH A;  3AQF B;  4DLO A;  2JND A;  2JOD A;  2JNC A;  3IOL A;  4HJ0 A;  1U34 A;  3N7R A;  3EHT A;  2L27 A;  3EHS A;  2XDG A;  3N7S A;  4DLQ A;  3C5T A;  4LF3 C;  3EHU A;  5II0 A;  4ZGM A;  3C4M A;  3L2J A;  4ERS A; 
#chains in the Genus database with same CATH topology
 3H3G A;  3C59 A;  3N7P A;  2QKH A;  3AQF B;  4DLO A;  2JND A;  2JOD A;  2JNC A;  3IOL A;  4HJ0 A;  1U34 A;  3N7R A;  3EHT A;  2L27 A;  3EHS A;  2XDG A;  3N7S A;  4DLQ A;  3C5T A;  4LF3 C;  3EHU A;  5II0 A;  4ZGM A;  3C4M A;  3L2J A;  4ERS A; 
#chains in the Genus database with same CATH homology
 3H3G A;  3C59 A;  3N7P A;  2QKH A;  3AQF B;  4DLO A;  2JND A;  2JOD A;  2JNC A;  3IOL A;  4HJ0 A;  1U34 A;  3N7R A;  3EHT A;  2L27 A;  3EHS A;  2XDG A;  3N7S A;  4DLQ A;  3C5T A;  4LF3 C;  3EHU A;  5II0 A;  4ZGM A;  3C4M A;  3L2J A;  4ERS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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