4ESQA

Crystal structure of the extracellular domain of pknh from mycobacterium tuberculosis
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
194
structure length
194
Chain Sequence
GHQPVAEERLSALLLNSSEVNAVMGSSSMQPGKPITSMDSSPVTVSLPDCQGALYTSQDPVYAGTGYTAINGLISSEPGDNYEHWVNQAVVAFPTADKARAFVQTSADKWKNCAGKTVTVTNKAKTYRWTFADVKGSPPTITVIDTQEGAEGWECQRAMSVANNVVVDVNACGYQITNQAGQIAAKIVDKVNKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords Serine/threonine protein kinase
publication title Structure of the sensor domain of Mycobacterium tuberculosis PknH receptor kinase reveals a conserved binding cleft.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 52
structure length 194
sequence length 194
ec nomenclature ec 2.7.11.1: Non-specific serine/threonine protein kinase.
pdb deposition date 2012-04-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14032 PknH_C PknH-like extracellular domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1000.70 Alpha Beta 3-Layer(aba) Sandwich Protein Transport Mog1p; Chain A Protein Transport Mog1p; Chain A 4esqA00
4ESQA
chains in the Genus database with same CATH superfamily
3BCYA 1V2BA 1VR8A 4N7SB 4RTIA 2LNJA 4N88B 4N80B 3NR5A 4BQ6D 3WA5B 4M5FB 4UI2D 4RTHA 3LYDA 3JCUP 4L9HA 1JHSA 4OUHA 4BQ8C 2XB3A 4L9CA 2VU4A 4LUQC 2VT8A 1EQ6A 1TU1A 3V7BA 4ESQA 3HLZA
chains in the Genus database with same CATH topology
3BCYA 4N88B 4N80B 3NR5A 4L9HA 3WA5B 4N7SB 4M5FB 4OUHA 4L9CA 4ESQA 4LUQC 2VT8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ESQ A; 
#chains in the Genus database with same CATH topology
 3BCY A;  1V2B A;  1VR8 A;  4N7S B;  4RTI A;  2LNJ A;  4N88 B;  4N80 B;  3NR5 A;  4BQ6 D;  3WA5 B;  4M5F B;  4UI2 D;  4RTH A;  3LYD A;  3JCU P;  4L9H A;  1JHS A;  4OUH A;  4BQ8 C;  2XB3 A;  4L9C A;  2VU4 A;  4LUQ C;  2VT8 A;  1EQ6 A;  1TU1 A;  3V7B A;  4ESQ A;  3HLZ A; 
#chains in the Genus database with same CATH homology
 3BCY A;  4N88 B;  4N80 B;  3NR5 A;  4L9H A;  3WA5 B;  4N7S B;  4M5F B;  4OUH A;  4L9C A;  4ESQ A;  4LUQ C;  2VT8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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