4F2CA

The crystal structure of a human mitoneet double mutant in which gly 66 are asp 67 are both replaced with ala residues
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
69
structure length
69
Chain Sequence
RNKAMINLHIQKDNPKIVHAFDMEDLAAKAVYCRCWRSKKFPFCDGAHTKHNEETGDNVGPLIIKKKET
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Allosteric control in a metalloprotein dramatically alters function.
pubmed doi rcsb
molecule tags Metal binding protein
source organism Homo sapiens
molecule keywords CDGSH iron-sulfur domain-containing protein 1
total genus 12
structure length 69
sequence length 69
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-05-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF09360 zf-CDGSH Iron-binding zinc finger CDGSH type
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.5.90 Alpha Beta 3-Layer(aba) Sandwich Ribosomal Protein L9; domain 1 Ribosomal Protein L9; domain 1 4f2cA00
4EZFA 4OOAA 3FNVA 3TBOA 4F2CA 2QH7A 3S2RA 4F1EA 4F28A 3EW0A 4OO7A 2R13A 3TBNA 3REEA 3S2QA 3LPQA 2QD0A
chains in the Genus database with same CATH superfamily
4EZFA 2Q9QB 2E9XD 5GHSC 2HJQA 2HBBA 4F28A 4OO7A 1DIVA 3TBNA 2HVFA 3LPQA 3FNDA 4FS8A 3FNVA 2Q9QA 2QH7A 2X49A 2E9XB 4RSRA 4FR0A 4KW7A 1CQUA 2LSMA 2QD0A 3CO4A 4FSDA 3TBOA 2EHOC 3S2RA 4F1EA 5GHRB 2OUTA 3REEA 3S2QA 3ANWA 4OOAA 2HBAA 4F2CA 4UY8H 3EW0A 5EG5A 2R13A 2X4AA 3J7ZH
chains in the Genus database with same CATH topology
4EZFA 2Q9QB 2E9XD 5GHSC 4F28A 4OO7A 3TBNA 3LPQA 4FS8A 3FNVA 2Q9QA 2QH7A 2X49A 2E9XB 4RSRA 4FR0A 4KW7A 2LSMA 2QD0A 4FSDA 3TBOA 2EHOC 3S2RA 4F1EA 5GHRB 2OUTA 3REEA 3S2QA 3ANWA 4OOAA 4F2CA 3EW0A 5EG5A 2R13A 2X4AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EZF A;  4OOA A;  3FNV A;  3TBO A;  4F2C A;  2QH7 A;  3S2R A;  4F1E A;  4F28 A;  3EW0 A;  4OO7 A;  2R13 A;  3TBN A;  3REE A;  3S2Q A;  3LPQ A;  2QD0 A; 
#chains in the Genus database with same CATH topology
 4EZF A;  2Q9Q B;  2E9X D;  5GHS C;  2HJQ A;  2HBB A;  4F28 A;  4OO7 A;  1DIV A;  3TBN A;  2HVF A;  3LPQ A;  3FND A;  4FS8 A;  3FNV A;  2Q9Q A;  2QH7 A;  2X49 A;  2E9X B;  4RSR A;  4FR0 A;  4KW7 A;  1CQU A;  2LSM A;  2QD0 A;  3CO4 A;  4FSD A;  3TBO A;  2EHO C;  3S2R A;  4F1E A;  5GHR B;  2OUT A;  3REE A;  3S2Q A;  3ANW A;  4OOA A;  2HBA A;  4F2C A;  4UY8 H;  3EW0 A;  5EG5 A;  2R13 A;  2X4A A;  3J7Z H; 
#chains in the Genus database with same CATH homology
 4EZF A;  2Q9Q B;  2E9X D;  5GHS C;  4F28 A;  4OO7 A;  3TBN A;  3LPQ A;  4FS8 A;  3FNV A;  2Q9Q A;  2QH7 A;  2X49 A;  2E9X B;  4RSR A;  4FR0 A;  4KW7 A;  2LSM A;  2QD0 A;  4FSD A;  3TBO A;  2EHO C;  3S2R A;  4F1E A;  5GHR B;  2OUT A;  3REE A;  3S2Q A;  3ANW A;  4OOA A;  4F2C A;  3EW0 A;  5EG5 A;  2R13 A;  2X4A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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