4F42A

Neurotrophin p75ntr intracellular domain
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
84
structure length
84
Chain Sequence
GNLYSSLPLTKREEVEKLLNGDTWRHLAGELGYQPEHIDSFTHEACPVRALLASWGAQDSATLDALLAALRRIQRADIVESLCS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the allosteric activation mechanism of p75NTR
rcsb
molecule tags Signaling protein
source organism Rattus norvegicus
molecule keywords Tumor necrosis factor receptor superfamily member 16
total genus 27
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2012-05-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.533.10 Mainly Alpha Orthogonal Bundle Death Domain, Fas Death Domain, Fas 4f42A00
4UZ0A 2YU0A 2LS7A 1A1ZA 3CRDA 2DBGA 2A5YB 4I16A 4QOBA 2OF5H 1WH4A 2NZ7A 2L9MA 4EWIA 4P4HI 2P1HA 3MOPA 2BBZA 2OF5A 1WMGA 2N1FA 2MS7A 1C15A 2N7ZA 4A2QA 1DDFA 2N80A 1YGOA 1NGRA 4LWDA 3J63A 4O9FA 3T6PA 2VGQA 2NAQA 2DO9A 2GF5A 2N00A 1Z6TA 4RHWA 2BBRA 4M9ZA 2DBFA 2MN4A 2MPCA 4DWNA 4O7QA 2N83A 4FH0A 4JQWA 1UCPA 1E3YA 4E9MA 2G7RA 1N3KA 2O71A 2A9IA 2F1SA 2KN6A 4N1JA 4O6XA 2DBHA 3EZQB 2NSNA 4N1LA 2MS8A 1D2ZB 2LWDA 4RHWE 1DGNA 3YGSP 3LQQA 3MOPG 2L6AA 4IZAB 4JUPA 3KATA 2KM6A 4A2WA 4F42A 2B1WA 2HM2Q 4M9XA 1CWWA 4F44A 1ICHA 4N1KA 3YGSC 2N97A 2DBDA 4ZBWA 4O9LA 2YGSA 1FADA 3MOPK 4IZ7B 3QF2A 4IZ5E 2M5VA 2IB1A 4M9SA 2D96A 2MB9A 1CY5A 2YQFA 3J6JA 3LQRA 2YVIA 1E41A 4P4HA 2LWEA 1A1WA 3CL3A 3EZQA 1PN5A 4NQKA 1D2ZA 1WXPA 4D8OA
chains in the Genus database with same CATH superfamily
4UZ0A 2YU0A 2LS7A 1A1ZA 3CRDA 2DBGA 2A5YB 4I16A 4QOBA 2OF5H 1WH4A 2NZ7A 2L9MA 4EWIA 4P4HI 2P1HA 3MOPA 2BBZA 2OF5A 1WMGA 2N1FA 2MS7A 1C15A 2N7ZA 4A2QA 1DDFA 2N80A 1YGOA 1NGRA 4LWDA 3J63A 4O9FA 3T6PA 2VGQA 2NAQA 2DO9A 2GF5A 2N00A 1Z6TA 4RHWA 2BBRA 4M9ZA 2DBFA 2MN4A 2MPCA 4DWNA 4O7QA 2N83A 4FH0A 4JQWA 2XV9A 1UCPA 1E3YA 4E9MA 2G7RA 1N3KA 2O71A 2A9IA 2F1SA 2KN6A 4N1JA 4O6XA 2DBHA 3EZQB 2NSNA 4N1LA 2MS8A 1D2ZB 2LWDA 4RHWE 1DGNA 3YGSP 3LQQA 3MOPG 2L6AA 4IZAB 4JUPA 3KATA 2KM6A 4A2WA 4F42A 2B1WA 2HM2Q 4M9XA 1CWWA 4F44A 1ICHA 4N1KA 3YGSC 2N97A 2DBDA 4ZBWA 4O9LA 2YGSA 1FADA 2MJMA 3MOPK 4IZ7B 3QF2A 4IZ5E 2M5VA 2IB1A 4M9SA 2D96A 2MB9A 1CY5A 2YQFA 3J6JA 3LQRA 2YVIA 1E41A 4P4HA 2LWEA 1A1WA 3CL3A 3EZQA 1PN5A 4NQKA 1D2ZA 1WXPA 4D8OA
chains in the Genus database with same CATH topology
4UZ0A 2YU0A 2LS7A 1A1ZA 3CRDA 2DBGA 2A5YB 4I16A 4QOBA 2OF5H 1WH4A 2NZ7A 2L9MA 4EWIA 4P4HI 2P1HA 3MOPA 2BBZA 2OF5A 1WMGA 2N1FA 2MS7A 1C15A 2N7ZA 4A2QA 1DDFA 2N80A 1YGOA 1NGRA 4LWDA 3J63A 4O9FA 3T6PA 2VGQA 2NAQA 2DO9A 2GF5A 2N00A 1Z6TA 4RHWA 2BBRA 4M9ZA 2DBFA 2MN4A 2MPCA 4DWNA 4O7QA 2N83A 4FH0A 4JQWA 2XV9A 1UCPA 1E3YA 4E9MA 2G7RA 1N3KA 2O71A 2A9IA 2F1SA 2KN6A 4N1JA 4O6XA 2DBHA 3EZQB 2NSNA 4N1LA 2MS8A 1D2ZB 2LWDA 4RHWE 1DGNA 3YGSP 3LQQA 3MOPG 2L6AA 4IZAB 4JUPA 3KATA 2KM6A 4A2WA 4F42A 2B1WA 2HM2Q 4M9XA 1CWWA 4F44A 1ICHA 4N1KA 3YGSC 2N97A 2DBDA 4ZBWA 4O9LA 2YGSA 1FADA 2MJMA 3MOPK 4IZ7B 3QF2A 4IZ5E 2M5VA 2IB1A 4M9SA 2D96A 2MB9A 1CY5A 2YQFA 3J6JA 3LQRA 2YVIA 1E41A 4P4HA 2LWEA 1A1WA 3CL3A 3EZQA 1PN5A 4NQKA 1D2ZA 1WXPA 4D8OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UZ0 A;  2YU0 A;  2LS7 A;  1A1Z A;  3CRD A;  2DBG A;  2A5Y B;  4I16 A;  4QOB A;  2OF5 H;  1WH4 A;  2NZ7 A;  2L9M A;  4EWI A;  4P4H I;  2P1H A;  3MOP A;  2BBZ A;  2OF5 A;  1WMG A;  2N1F A;  2MS7 A;  1C15 A;  2N7Z A;  4A2Q A;  1DDF A;  2N80 A;  1YGO A;  1NGR A;  4LWD A;  3J63 A;  4O9F A;  3T6P A;  2VGQ A;  2NAQ A;  2DO9 A;  2GF5 A;  2N00 A;  1Z6T A;  4RHW A;  2BBR A;  4M9Z A;  2DBF A;  2MN4 A;  2MPC A;  4DWN A;  4O7Q A;  2N83 A;  4FH0 A;  4JQW A;  1UCP A;  1E3Y A;  4E9M A;  2G7R A;  1N3K A;  2O71 A;  2A9I A;  2F1S A;  2KN6 A;  4N1J A;  4O6X A;  2DBH A;  3EZQ B;  2NSN A;  4N1L A;  2MS8 A;  1D2Z B;  2LWD A;  4RHW E;  1DGN A;  3YGS P;  3LQQ A;  3MOP G;  2L6A A;  4IZA B;  4JUP A;  3KAT A;  2KM6 A;  4A2W A;  4F42 A;  2B1W A;  2HM2 Q;  4M9X A;  1CWW A;  4F44 A;  1ICH A;  4N1K A;  3YGS C;  2N97 A;  2DBD A;  4ZBW A;  4O9L A;  2YGS A;  1FAD A;  3MOP K;  4IZ7 B;  3QF2 A;  4IZ5 E;  2M5V A;  2IB1 A;  4M9S A;  2D96 A;  2MB9 A;  1CY5 A;  2YQF A;  3J6J A;  3LQR A;  2YVI A;  1E41 A;  4P4H A;  2LWE A;  1A1W A;  3CL3 A;  3EZQ A;  1PN5 A;  4NQK A;  1D2Z A;  1WXP A;  4D8O A; 
#chains in the Genus database with same CATH topology
 4UZ0 A;  2YU0 A;  2LS7 A;  1A1Z A;  3CRD A;  2DBG A;  2A5Y B;  4I16 A;  4QOB A;  2OF5 H;  1WH4 A;  2NZ7 A;  2L9M A;  4EWI A;  4P4H I;  2P1H A;  3MOP A;  2BBZ A;  2OF5 A;  1WMG A;  2N1F A;  2MS7 A;  1C15 A;  2N7Z A;  4A2Q A;  1DDF A;  2N80 A;  1YGO A;  1NGR A;  4LWD A;  3J63 A;  4O9F A;  3T6P A;  2VGQ A;  2NAQ A;  2DO9 A;  2GF5 A;  2N00 A;  1Z6T A;  4RHW A;  2BBR A;  4M9Z A;  2DBF A;  2MN4 A;  2MPC A;  4DWN A;  4O7Q A;  2N83 A;  4FH0 A;  4JQW A;  2XV9 A;  1UCP A;  1E3Y A;  4E9M A;  2G7R A;  1N3K A;  2O71 A;  2A9I A;  2F1S A;  2KN6 A;  4N1J A;  4O6X A;  2DBH A;  3EZQ B;  2NSN A;  4N1L A;  2MS8 A;  1D2Z B;  2LWD A;  4RHW E;  1DGN A;  3YGS P;  3LQQ A;  3MOP G;  2L6A A;  4IZA B;  4JUP A;  3KAT A;  2KM6 A;  4A2W A;  4F42 A;  2B1W A;  2HM2 Q;  4M9X A;  1CWW A;  4F44 A;  1ICH A;  4N1K A;  3YGS C;  2N97 A;  2DBD A;  4ZBW A;  4O9L A;  2YGS A;  1FAD A;  2MJM A;  3MOP K;  4IZ7 B;  3QF2 A;  4IZ5 E;  2M5V A;  2IB1 A;  4M9S A;  2D96 A;  2MB9 A;  1CY5 A;  2YQF A;  3J6J A;  3LQR A;  2YVI A;  1E41 A;  4P4H A;  2LWE A;  1A1W A;  3CL3 A;  3EZQ A;  1PN5 A;  4NQK A;  1D2Z A;  1WXP A;  4D8O A; 
#chains in the Genus database with same CATH homology
 4UZ0 A;  2YU0 A;  2LS7 A;  1A1Z A;  3CRD A;  2DBG A;  2A5Y B;  4I16 A;  4QOB A;  2OF5 H;  1WH4 A;  2NZ7 A;  2L9M A;  4EWI A;  4P4H I;  2P1H A;  3MOP A;  2BBZ A;  2OF5 A;  1WMG A;  2N1F A;  2MS7 A;  1C15 A;  2N7Z A;  4A2Q A;  1DDF A;  2N80 A;  1YGO A;  1NGR A;  4LWD A;  3J63 A;  4O9F A;  3T6P A;  2VGQ A;  2NAQ A;  2DO9 A;  2GF5 A;  2N00 A;  1Z6T A;  4RHW A;  2BBR A;  4M9Z A;  2DBF A;  2MN4 A;  2MPC A;  4DWN A;  4O7Q A;  2N83 A;  4FH0 A;  4JQW A;  2XV9 A;  1UCP A;  1E3Y A;  4E9M A;  2G7R A;  1N3K A;  2O71 A;  2A9I A;  2F1S A;  2KN6 A;  4N1J A;  4O6X A;  2DBH A;  3EZQ B;  2NSN A;  4N1L A;  2MS8 A;  1D2Z B;  2LWD A;  4RHW E;  1DGN A;  3YGS P;  3LQQ A;  3MOP G;  2L6A A;  4IZA B;  4JUP A;  3KAT A;  2KM6 A;  4A2W A;  4F42 A;  2B1W A;  2HM2 Q;  4M9X A;  1CWW A;  4F44 A;  1ICH A;  4N1K A;  3YGS C;  2N97 A;  2DBD A;  4ZBW A;  4O9L A;  2YGS A;  1FAD A;  2MJM A;  3MOP K;  4IZ7 B;  3QF2 A;  4IZ5 E;  2M5V A;  2IB1 A;  4M9S A;  2D96 A;  2MB9 A;  1CY5 A;  2YQF A;  3J6J A;  3LQR A;  2YVI A;  1E41 A;  4P4H A;  2LWE A;  1A1W A;  3CL3 A;  3EZQ A;  1PN5 A;  4NQK A;  1D2Z A;  1WXP A;  4D8O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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