4FVAA

Crystal structure of truncated caenorhabditis elegans tdp2
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
249
structure length
249
Chain Sequence
DLKGFEVSVMSWNIDGLDGRSLLTRMKAVAHIVKNVNPDILFLQEVVDRDLAPIDKLQSLYKIYYSNKGCQYYTAILVSKMFDVEKHDVIHFQNSGMYRTLQILEGSIGGLKVFLLNTHLESTREHRPQRCAQFGFCMDKVREIIAQNPGALVFFGGDLNLRDEEVSRVPDGVKDAWEAAGSDNKTKFTWDTFKNDNKQGFHGAKMRFDRLYWSGPLDKVKFTLEGRQRIRSCLCFPSDHWAINATFFA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
pubmed doi rcsb
molecule tags Hydrolase
source organism Caenorhabditis elegans
molecule keywords 5'-tyrosyl-DNA phosphodiesterase
total genus 81
structure length 249
sequence length 249
chains with identical sequence B, C, D
ec nomenclature ec 3.1.4.-:
pdb deposition date 2012-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03372 Exo_endo_phos Endonuclease/Exonuclease/phosphatase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.10.10 Alpha Beta 4-Layer Sandwich Deoxyribonuclease I; Chain A Endonuclease/exonuclease/phosphatase 4fvaA00
4B5MA 3G0RA 3NGQA 1BIXA 5INKA 3G3YA 5CFGA 4L21A 3I46A 2V0RA 1ZWXA 3G91A 5EWTA 2DDTA 1DNKA 1E9NA 1I9ZA 2D1KB 3L1WA 4RUWA 3N9VA 5INMA 1ATND 1DE8A 1Y21A 5J42A 3G3CA 3W3DB 2O3HA 3MPRA 3U8UA 5DFIA 4FPVA 4GZ2A 4B5GA 5DFJA 2IMQX 5INNA 4L1YA 3G8VA 4B5HA 1DE9A 1YJHA 2A42B 3G38A 4QHEA 2A40B 4B5FA 1DEWA 3MTCA 5DFHA 2F2FB 3DNIA 1AKOA 4CMLA 2EI9A 3G6SA 3WCXA 2DNJA 4F1HB 2ISIA 5J3ZA 3TEBA 2JC5A 3G2CA 5HT2A 4AWNA 4GYZA 4PUQA 5DFFA 2A41B 3G1KA 3K55A 3G00A 2A3ZB 3NR8A 5A7JA 5CFEA 2F1NA 4F1HA 1SR4B 3FZIA 5INOA 5INQA 5J8NA 4C1RA 2DDRA 4K6LF 2XSWA 2V0SA 5INPA 1HD7A 3W2YA 4B5IA 5A7IA 5DG0A 2J63A 3CJCD 1WDUA 5DV4A 4FVAA 4GZ0A 3G2DA 5DV2A 1NTFA 4F1IA 5INLA 5J3PA 3I48A 2JC4A 3I5VA 3NGOA 4GZ1A 4CMNA 4LNDA 2DDSA 4L20A 2O3CA 2VOAA 1SI6X 3I41A 3G0AA 3G4TA 4L1ZA 4F1RA 3NGNA 1I9YA 4IEMA 5J3SA 4QHDA 1VYBA 4GEWA 4QH9A 3GA6A 4A9CA 3W2XA 4B5JA 4JG3A 2UYRX
chains in the Genus database with same CATH superfamily
4B5MA 3G0RA 3NGQA 1BIXA 5INKA 3G3YA 5CFGA 4L21A 3I46A 2V0RA 1ZWXA 3G91A 5EWTA 2DDTA 1DNKA 1E9NA 1I9ZA 2D1KB 3L1WA 4RUWA 3N9VA 5INMA 1ATND 1DE8A 1Y21A 5J42A 3G3CA 3W3DB 2O3HA 3MPRA 3U8UA 5DFIA 4FPVA 4GZ2A 4B5GA 5DFJA 2IMQX 5INNA 4L1YA 3G8VA 4B5HA 1DE9A 1YJHA 2A42B 3G38A 4QHEA 2A40B 4B5FA 1DEWA 3MTCA 5DFHA 2F2FB 3DNIA 1AKOA 4CMLA 2EI9A 3G6SA 3WCXA 2DNJA 4F1HB 2ISIA 5J3ZA 3TEBA 2JC5A 3G2CA 5HT2A 4AWNA 4GYZA 4PUQA 5DFFA 2A41B 3G1KA 3K55A 3G00A 2A3ZB 3NR8A 5A7JA 5CFEA 2F1NA 4F1HA 1SR4B 3FZIA 5INOA 5INQA 5J8NA 4C1RA 2DDRA 4K6LF 2XSWA 2V0SA 5INPA 1HD7A 3W2YA 4B5IA 5A7IA 5DG0A 2J63A 3CJCD 1WDUA 5DV4A 4FVAA 4GZ0A 3G2DA 5DV2A 1NTFA 4F1IA 5INLA 5J3PA 3I48A 2JC4A 3I5VA 3NGOA 4GZ1A 4CMNA 4LNDA 2DDSA 4L20A 2O3CA 2VOAA 1SI6X 3I41A 3G0AA 3G4TA 4L1ZA 4F1RA 3NGNA 1I9YA 4IEMA 5J3SA 4QHDA 1VYBA 4GEWA 4QH9A 3GA6A 4A9CA 3W2XA 4B5JA 4JG3A 2UYRX
chains in the Genus database with same CATH topology
4B5MA 3G0RA 3NGQA 1BIXA 5INKA 3G3YA 5CFGA 4L21A 3I46A 2V0RA 1ZWXA 3G91A 5EWTA 2DDTA 1DNKA 1E9NA 1I9ZA 2D1KB 3L1WA 4RUWA 3N9VA 5INMA 1ATND 1DE8A 1Y21A 5J42A 3G3CA 3W3DB 2O3HA 3MPRA 3U8UA 5DFIA 4FPVA 4GZ2A 4B5GA 5DFJA 2IMQX 5INNA 4L1YA 3G8VA 4B5HA 1DE9A 1YJHA 2A42B 3G38A 4QHEA 2A40B 4B5FA 1DEWA 3MTCA 5DFHA 2F2FB 3DNIA 1AKOA 4CMLA 2EI9A 3G6SA 3WCXA 2DNJA 4F1HB 2ISIA 5J3ZA 3TEBA 2JC5A 3G2CA 5HT2A 4AWNA 4GYZA 4PUQA 5DFFA 2A41B 3G1KA 3K55A 3G00A 2A3ZB 3NR8A 5A7JA 5CFEA 2F1NA 4F1HA 1SR4B 3FZIA 5INOA 5INQA 5J8NA 4C1RA 2DDRA 4K6LF 2XSWA 2V0SA 5INPA 1HD7A 3W2YA 4B5IA 5A7IA 5DG0A 2J63A 3CJCD 1WDUA 5DV4A 4FVAA 4GZ0A 3G2DA 5DV2A 1NTFA 4F1IA 5INLA 5J3PA 3I48A 2JC4A 3I5VA 3NGOA 4GZ1A 4CMNA 4LNDA 2DDSA 4L20A 2O3CA 2VOAA 1SI6X 3I41A 3G0AA 3G4TA 4L1ZA 4F1RA 3NGNA 1I9YA 4IEMA 5J3SA 4QHDA 1VYBA 4GEWA 4QH9A 3GA6A 4A9CA 3W2XA 4B5JA 4JG3A 2UYRX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4B5M A;  3G0R A;  3NGQ A;  1BIX A;  5INK A;  3G3Y A;  5CFG A;  4L21 A;  3I46 A;  2V0R A;  1ZWX A;  3G91 A;  5EWT A;  2DDT A;  1DNK A;  1E9N A;  1I9Z A;  2D1K B;  3L1W A;  4RUW A;  3N9V A;  5INM A;  1ATN D;  1DE8 A;  1Y21 A;  5J42 A;  3G3C A;  3W3D B;  2O3H A;  3MPR A;  3U8U A;  5DFI A;  4FPV A;  4GZ2 A;  4B5G A;  5DFJ A;  2IMQ X;  5INN A;  4L1Y A;  3G8V A;  4B5H A;  1DE9 A;  1YJH A;  2A42 B;  3G38 A;  4QHE A;  2A40 B;  4B5F A;  1DEW A;  3MTC A;  5DFH A;  2F2F B;  3DNI A;  1AKO A;  4CML A;  2EI9 A;  3G6S A;  3WCX A;  2DNJ A;  4F1H B;  2ISI A;  5J3Z A;  3TEB A;  2JC5 A;  3G2C A;  5HT2 A;  4AWN A;  4GYZ A;  4PUQ A;  5DFF A;  2A41 B;  3G1K A;  3K55 A;  3G00 A;  2A3Z B;  3NR8 A;  5A7J A;  5CFE A;  2F1N A;  4F1H A;  1SR4 B;  3FZI A;  5INO A;  5INQ A;  5J8N A;  4C1R A;  2DDR A;  4K6L F;  2XSW A;  2V0S A;  5INP A;  1HD7 A;  3W2Y A;  4B5I A;  5A7I A;  5DG0 A;  2J63 A;  3CJC D;  1WDU A;  5DV4 A;  4FVA A;  4GZ0 A;  3G2D A;  5DV2 A;  1NTF A;  4F1I A;  5INL A;  5J3P A;  3I48 A;  2JC4 A;  3I5V A;  3NGO A;  4GZ1 A;  4CMN A;  4LND A;  2DDS A;  4L20 A;  2O3C A;  2VOA A;  1SI6 X;  3I41 A;  3G0A A;  3G4T A;  4L1Z A;  4F1R A;  3NGN A;  1I9Y A;  4IEM A;  5J3S A;  4QHD A;  1VYB A;  4GEW A;  4QH9 A;  3GA6 A;  4A9C A;  3W2X A;  4B5J A;  4JG3 A;  2UYR X; 
#chains in the Genus database with same CATH topology
 4B5M A;  3G0R A;  3NGQ A;  1BIX A;  5INK A;  3G3Y A;  5CFG A;  4L21 A;  3I46 A;  2V0R A;  1ZWX A;  3G91 A;  5EWT A;  2DDT A;  1DNK A;  1E9N A;  1I9Z A;  2D1K B;  3L1W A;  4RUW A;  3N9V A;  5INM A;  1ATN D;  1DE8 A;  1Y21 A;  5J42 A;  3G3C A;  3W3D B;  2O3H A;  3MPR A;  3U8U A;  5DFI A;  4FPV A;  4GZ2 A;  4B5G A;  5DFJ A;  2IMQ X;  5INN A;  4L1Y A;  3G8V A;  4B5H A;  1DE9 A;  1YJH A;  2A42 B;  3G38 A;  4QHE A;  2A40 B;  4B5F A;  1DEW A;  3MTC A;  5DFH A;  2F2F B;  3DNI A;  1AKO A;  4CML A;  2EI9 A;  3G6S A;  3WCX A;  2DNJ A;  4F1H B;  2ISI A;  5J3Z A;  3TEB A;  2JC5 A;  3G2C A;  5HT2 A;  4AWN A;  4GYZ A;  4PUQ A;  5DFF A;  2A41 B;  3G1K A;  3K55 A;  3G00 A;  2A3Z B;  3NR8 A;  5A7J A;  5CFE A;  2F1N A;  4F1H A;  1SR4 B;  3FZI A;  5INO A;  5INQ A;  5J8N A;  4C1R A;  2DDR A;  4K6L F;  2XSW A;  2V0S A;  5INP A;  1HD7 A;  3W2Y A;  4B5I A;  5A7I A;  5DG0 A;  2J63 A;  3CJC D;  1WDU A;  5DV4 A;  4FVA A;  4GZ0 A;  3G2D A;  5DV2 A;  1NTF A;  4F1I A;  5INL A;  5J3P A;  3I48 A;  2JC4 A;  3I5V A;  3NGO A;  4GZ1 A;  4CMN A;  4LND A;  2DDS A;  4L20 A;  2O3C A;  2VOA A;  1SI6 X;  3I41 A;  3G0A A;  3G4T A;  4L1Z A;  4F1R A;  3NGN A;  1I9Y A;  4IEM A;  5J3S A;  4QHD A;  1VYB A;  4GEW A;  4QH9 A;  3GA6 A;  4A9C A;  3W2X A;  4B5J A;  4JG3 A;  2UYR X; 
#chains in the Genus database with same CATH homology
 4B5M A;  3G0R A;  3NGQ A;  1BIX A;  5INK A;  3G3Y A;  5CFG A;  4L21 A;  3I46 A;  2V0R A;  1ZWX A;  3G91 A;  5EWT A;  2DDT A;  1DNK A;  1E9N A;  1I9Z A;  2D1K B;  3L1W A;  4RUW A;  3N9V A;  5INM A;  1ATN D;  1DE8 A;  1Y21 A;  5J42 A;  3G3C A;  3W3D B;  2O3H A;  3MPR A;  3U8U A;  5DFI A;  4FPV A;  4GZ2 A;  4B5G A;  5DFJ A;  2IMQ X;  5INN A;  4L1Y A;  3G8V A;  4B5H A;  1DE9 A;  1YJH A;  2A42 B;  3G38 A;  4QHE A;  2A40 B;  4B5F A;  1DEW A;  3MTC A;  5DFH A;  2F2F B;  3DNI A;  1AKO A;  4CML A;  2EI9 A;  3G6S A;  3WCX A;  2DNJ A;  4F1H B;  2ISI A;  5J3Z A;  3TEB A;  2JC5 A;  3G2C A;  5HT2 A;  4AWN A;  4GYZ A;  4PUQ A;  5DFF A;  2A41 B;  3G1K A;  3K55 A;  3G00 A;  2A3Z B;  3NR8 A;  5A7J A;  5CFE A;  2F1N A;  4F1H A;  1SR4 B;  3FZI A;  5INO A;  5INQ A;  5J8N A;  4C1R A;  2DDR A;  4K6L F;  2XSW A;  2V0S A;  5INP A;  1HD7 A;  3W2Y A;  4B5I A;  5A7I A;  5DG0 A;  2J63 A;  3CJC D;  1WDU A;  5DV4 A;  4FVA A;  4GZ0 A;  3G2D A;  5DV2 A;  1NTF A;  4F1I A;  5INL A;  5J3P A;  3I48 A;  2JC4 A;  3I5V A;  3NGO A;  4GZ1 A;  4CMN A;  4LND A;  2DDS A;  4L20 A;  2O3C A;  2VOA A;  1SI6 X;  3I41 A;  3G0A A;  3G4T A;  4L1Z A;  4F1R A;  3NGN A;  1I9Y A;  4IEM A;  5J3S A;  4QHD A;  1VYB A;  4GEW A;  4QH9 A;  3GA6 A;  4A9C A;  3W2X A;  4B5J A;  4JG3 A;  2UYR X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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