4FVLA

Human collagenase 3 (mmp-13) full form with peptides from pro-domain
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
368
structure length
368
Chain Sequence
YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHAFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Collagenase 3
total genus 92
structure length 368
sequence length 368
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2012-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00045 Hemopexin Hemopexin
A PF00413 Peptidase_M10 Matrixin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.110.10.10 Mainly Beta 4 Propeller Hemopexin Hemopexin-like domain 4fvlA02
3.40.390.10 Alpha Beta 3-Layer(aba) Sandwich Collagenase (Catalytic Domain) Collagenase (Catalytic Domain) 4fvlA01
4HX3A 2TCLA 1XFVA 1C3IA 1MMPA 3LIKA 2ERPA 4PKVA 2OVZA 1KUFA 1CAQA 3EHXA 4IJOA 3HBUP 1OS2A 3LEAA 4FVLA 1HFSA 1L6JA 1KUGA 3HDBA 1PWQA 2CLTA 4PKRA 2Y6DA 3Q2GA 4FXQA 4I35A 3OYOA 4L19A 1PWVA 1XUDA 3SHIA 1CQRA 1PWPA 1KUHA 2FV9A 2OXUA 1MMQA 1ZS0A 1BZSA 1UTTA 5I4OA 4GWMA 1ZXVA 4GR8A 4PKTA 1QJSA 2JXYA 1GKCA 2DW0A 3B92A 3DL1A 1GE6A 1K7QA 3I7GA 2ERQA 1I1IP 3O2XA 1ZVXA 1ASTA 3LUNA 1BQOA 3OHOA 3L0TA 1XURA 3LJGA 1JIWP 4AUOA 1R1HA 1Y93A 3AYUA 3NX7A 5D1TA 3F15A 1G05A 1I76A 3EWJA 1IACA 2W12A 1ZP5A 4QKZA 1G49A 1KUKA 5I0LA 4L6TA 3O64A 1HV5A 3LJTA 1EAKA 1Y8JA 3DWBA 3TVCA 2AIGP 3HBVP 1JAQA 1IADA 1XFUA 2DW2A 2HU6A 1UEAA 4XBHA 1QUAA 1SRPA 2SRTA 1K7IA 3P24A 2D1OA 1JANA 5CXAA 3OHLA 4GQLA 1A86A 3TS4A 3DPEA 1QIBA 4AYKA 2OXZA 1RTGA 1B3DA 1K7GA 4JIJA 4Q1LA 1GE5A 1MMRA 4FU4A 3WV3A 3KMCA 2W13A 4DF9A 4GR0A 2X7MA 5H8XA 5BOYA 4OEIA 1CIZA 1S4BP 1BM6A 3EHYA 966CA 1HY7A 1SU3A 1YP1A 5CUHA 3E8RA 5I3MA 2DDFA 1EUBA 1CGFA 4G9LA 1GENA 3LUMA 5LABA 2X3CA 4HMAA 4H3XA 4WZVA 1FM1A 1AKLA 2KRJA 2V4BA 3V6NA 2JT6A 3LIRA 4H84A 4IN9A 2O36A 1CXVA 2OZRA 5D1SA 2MZEA 1O0TA 1D8MA 3I7IA 1Z3JA 1FBLA 1IABA 1MNCA 5B5OA 3HDAP 2MLRA 2OY4A 3B8ZA 1OMJA 1FLSA 3LJZA 2OW1A 1DMTA 4RT6B 4GUYA 4PKUA 1KBCA 1B8YA 4R3VA 3VTGA 2MZHA 4L63A 2O3EA 1GKDA 3HY9A 3HB2P 3ZXHA 1ND1A 1WNIA 1CGEA 1BKCI 1HFCA 1D5JA 4JP4A 3P1VA 1QICA 3B2ZA 3G5CA 2I47A 1GO8P 2W14A 2D1NA 3F19A 1YQYA 1IAGA 3GBOA 4CTHA 3K7NA 3KEKA 3LE9A 2CKIA 1JJ9A 830CA 1ROSA 2PJTA 4EFSA 2MQSA 1OM8A 1MMBA 456CA 2RJQA 4IUWA 3U1RA 3HY7A 1BUDA 1KAPP 1IAEA 1JAPA 2K9CA 5D1UA 2QPJA 4WKEA 2JT5A 4WKIA 4H49A 1JIZA 1J7NA 3AYKA 4XCTA 2MZIA 2FV5A 1AF0A 4PKSA 3KRYA 1JAOA 1QJIA 1BUVM 4PKQA 1SLNA 1OM6A 2OW9A 2POJA 4LL2A 1GXDA 3ZUKA 3WV2A 4XM8A 1GO7P 4H76A 3KEJA 5B5PA 4FXYP 2DW1A 5JMYA 1IAAA 1D7XA 2JNPA 3F18A 3G42A 2AYKA 5CZMA 2J83A 5I43A 2L0RA 3EDZA 1KUIA 2WOAA 4J4MA 1SATA 5BOTA 3USNA 3CKIA 1XUCA 1CGLA 4H2EA 3RTSA 1QHUA 1EB6A 3LQBA 2OW0A 4H1QA 3L0VA 2OI0A 1BIWA 1ZTQA 1HTDA 1ATLA 1SMPA 2OXWA 3AIGA 1BKCA 1OM7A 1BKCE 3DPFA 3F17A 2K2GA 5I2ZA 3KMEA 1O0QA 3LMCA 1JH1A 2JSDA 3TSKA 3ZVSA 3WV1A 4YEHA 4ZR5A 1QJJA 1XFYA 1JK3A 2YB9A 2Z2DA 1RM8A 1SLMA 1ITVA 1C7KA 3BA0A 4JQGA 2WO9A 2A8HA 4GR3A 1BSWA 3S18A 1RMZA 4DV8A 4WF6A 2USNA 4A7BA 1HOVA 2XS4A 3EDGA 4WK7A 5D7WA 4JA1A 4XM7A 3KECA 1PWWA 3MA2A 1G12A 2E2DA 2Y6CA 5L79A 3RTTA 4JPAA 2JIHA 2WO8A 1R54A 4ILWD 3F1AA 1BQQM 3LGPA 1HXNA 1JKYA 5I12A 1G4KA 5D2BA 4HSDA 1R1JA 1UMSA 4PKWA 3LILA 1UMTA 3TT4A 4AIGA 1G9KA 3DSLA 1OO9A 2YIGA 1PWUA 2RJPA 1USNA 1XFXA 3KHIA 4AXQA 3N2UA 1R55A 3V96B 4ON1A 3ELMA 1C8TA 2W0DA 5L7FA 2MLSA 4I03A 1XFWA 3KWVC 1PEXA 2N8RA 1QIAA 3HYGA 1D8FA 3LQ0A 2DDYA 4H30A 4DPEA 4DD8A 3K7LA 1CK7A 2OW2A 4GWNA 3C7XA 1YCMA 5BPAA 1UTZA 3LP9A 1AYKA 3UVCA 3F16A 1ZXCA 1DTHA 2J0TA 1A85A 3LK8A 1OS9A 3N2VA 1Q3AA 2W15A 2E3XA 2X3AA 1XFZA 3EDIA 1YOUA 4GF1A 2XS3A 3VI1A 4A3WA 1GE7A 5D3CA 4XM6A 2X3BA 3EDHA 2OVXA 1R1IA 1H71P 4H82A 1I73A 3Q2HA 3DNGA 3LKAA 1Y0VA 4G0DA 2EROA 2OY2A
chains in the Genus database with same CATH superfamily
4HX3A 2TCLA 1XFVA 1C3IA 1MMPA 3LIKA 2ERPA 4PKVA 2OVZA 1KUFA 1CAQA 3EHXA 4IJOA 3HBUP 1OS2A 3LEAA 4FVLA 1HFSA 1L6JA 1KUGA 3HDBA 1PWQA 2CLTA 4PKRA 2Y6DA 3Q2GA 4FXQA 4I35A 3OYOA 4L19A 1PWVA 1XUDA 3SHIA 1CQRA 1PWPA 1KUHA 2FV9A 2OXUA 1MMQA 1ZS0A 1BZSA 1UTTA 5I4OA 4GWMA 1ZXVA 4GR8A 4PKTA 1QJSA 2JXYA 1GKCA 2DW0A 3B92A 3DL1A 1GE6A 1K7QA 3I7GA 2ERQA 1I1IP 3O2XA 1ZVXA 1ASTA 3LUNA 1BQOA 3OHOA 3L0TA 1XURA 3LJGA 1JIWP 4AUOA 1R1HA 1Y93A 3AYUA 3NX7A 5D1TA 3F15A 1G05A 1I76A 3EWJA 1IACA 2W12A 1ZP5A 4QKZA 1G49A 1KUKA 4L7AA 5I0LA 4L6TA 3O64A 1HV5A 3LJTA 1EAKA 1Y8JA 3DWBA 3TVCA 2AIGP 3HBVP 1JAQA 1IADA 1XFUA 2DW2A 2HU6A 1UEAA 4XBHA 1QUAA 1SRPA 2SRTA 1K7IA 3P24A 2D1OA 1XM5A 1JANA 5CXAA 3OHLA 4GQLA 1A86A 3TS4A 3DPEA 1QIBA 4AYKA 2OXZA 1RTGA 1B3DA 1K7GA 4JIJA 4Q1LA 1GE5A 1MMRA 4FU4A 3DTKA 3WV3A 3KMCA 2W13A 4DF9A 4GR0A 2X7MA 5H8XA 1TVIA 5BOYA 4OEIA 1CIZA 1S4BP 1BM6A 3EHYA 966CA 1HY7A 1SU3A 1YP1A 5CUHA 1XAXA 3E8RA 5I3MA 2DDFA 1EUBA 1CGFA 4G9LA 1GENA 3LUMA 5LABA 2X3CA 4HMAA 4H3XA 4WZVA 1FM1A 1AKLA 2KRJA 2V4BA 3V6NA 2JT6A 3LIRA 4H84A 4IN9A 2O36A 1CXVA 2OZRA 5D1SA 2MZEA 1O0TA 1D8MA 3I7IA 1Z3JA 2YUFA 1FBLA 1IABA 1MNCA 5B5OA 3HDAP 2MLRA 2OY4A 3B8ZA 1OMJA 1FLSA 3LJZA 2OW1A 1DMTA 4RT6B 4GUYA 4PKUA 1KBCA 1B8YA 4R3VA 3VTGA 2MZHA 4L63A 2O3EA 1GKDA 3HY9A 3HB2P 3ZXHA 1ND1A 1WNIA 1CGEA 1BKCI 1HFCA 1D5JA 4JP4A 3P1VA 1QICA 3B2ZA 3G5CA 2I47A 1GO8P 2W14A 2D1NA 3F19A 1YQYA 1IAGA 3GBOA 4CTHA 3K7NA 3KEKA 3LE9A 2CKIA 1JJ9A 830CA 1ROSA 2PJTA 4EFSA 2MQSA 1OM8A 1MMBA 456CA 2RJQA 4IUWA 3U1RA 3HY7A 1BUDA 1KAPP 1IAEA 1JAPA 2K9CA 5D1UA 2QPJA 4WKEA 2JT5A 4WKIA 4H49A 1JIZA 1J7NA 3AYKA 4XCTA 2MZIA 2FV5A 1AF0A 4PKSA 3KRYA 1JAOA 1QJIA 1BUVM 4PKQA 1SLNA 1OM6A 2OW9A 2POJA 4LL2A 1GXDA 3ZUKA 3WV2A 4XM8A 1GO7P 4H76A 3KEJA 5B5PA 4FXYP 2DW1A 5JMYA 1IAAA 1D7XA 2JNPA 3F18A 3G42A 2AYKA 5CZMA 2J83A 5I43A 2L0RA 3EDZA 1KUIA 2WOAA 4J4MA 3DTEA 1SATA 5BOTA 3USNA 3CKIA 1XUCA 1CGLA 4H2EA 3RTSA 1QHUA 1EB6A 3LQBA 2OW0A 4H1QA 3L0VA 2OI0A 1BIWA 1ZTQA 1HTDA 1ATLA 1SMPA 2OXWA 3AIGA 1BKCA 1OM7A 1BKCE 3DPFA 3F17A 2K2GA 5I2ZA 3KMEA 1O0QA 3LMCA 1JH1A 2JSDA 3TSKA 3ZVSA 3WV1A 4YEHA 4ZR5A 1QJJA 1XFYA 1JK3A 2YB9A 2Z2DA 1RM8A 1SLMA 1ITVA 1C7KA 3BA0A 4JQGA 2WO9A 2A8HA 4GR3A 1BSWA 3S18A 1RMZA 4DV8A 4WF6A 2USNA 4A7BA 1HOVA 2XS4A 3EDGA 4WK7A 5D7WA 4JA1A 4XM7A 3KECA 1PWWA 3MA2A 1G12A 2E2DA 2Y6CA 5L79A 3RTTA 4JPAA 2JIHA 2WO8A 1R54A 4ILWD 3F1AA 1BQQM 3LGPA 1HXNA 1JKYA 5I12A 1G4KA 1OZ9A 5D2BA 4HSDA 1R1JA 1UMSA 4PKWA 3LILA 1UMTA 3TT4A 4AIGA 1G9KA 3DSLA 1OO9A 2YIGA 1PWUA 2RJPA 1USNA 1XFXA 3KHIA 4AXQA 3N2UA 1R55A 3V96B 4ON1A 3ELMA 1C8TA 2W0DA 5L7FA 2MLSA 4I03A 1XFWA 3KWVC 1PEXA 2N8RA 1QIAA 3HYGA 1D8FA 3LQ0A 2DDYA 4H30A 4DPEA 4DD8A 3K7LA 1CK7A 2OW2A 4GWNA 3C7XA 1YCMA 5BPAA 1UTZA 3LP9A 1AYKA 3UVCA 3F16A 1ZXCA 3DTIA 1DTHA 2J0TA 1A85A 3LK8A 1OS9A 3N2VA 1Q3AA 2W15A 2E3XA 2X3AA 1XFZA 3EDIA 1YOUA 4GF1A 2XS3A 3VI1A 4A3WA 1GE7A 5D3CA 4XM6A 2X3BA 3EDHA 2OVXA 1R1IA 1H71P 4H82A 1I73A 3Q2HA 3DNGA 3LKAA 1Y0VA 4G0DA 2EROA 2OY2A
chains in the Genus database with same CATH topology
4HX3A 2TCLA 1XFVA 1C3IA 1MMPA 3LIKA 2ERPA 4PKVA 2OVZA 1KUFA 1CAQA 3EHXA 4IJOA 3HBUP 1OS2A 3LEAA 4FVLA 1HFSA 1L6JA 1KUGA 3HDBA 1PWQA 2CLTA 4PKRA 2Y6DA 3Q2GA 4FXQA 4I35A 3OYOA 4L19A 1PWVA 1XUDA 3SHIA 1CQRA 1PWPA 1KUHA 2FV9A 2OXUA 1MMQA 1ZS0A 1BZSA 1UTTA 5I4OA 4GWMA 1ZXVA 4GR8A 4PKTA 1QJSA 2JXYA 1GKCA 2DW0A 3B92A 3DL1A 1GE6A 1K7QA 3I7GA 2ERQA 1I1IP 3O2XA 1ZVXA 1ASTA 3LUNA 1BQOA 3OHOA 3L0TA 1XURA 3LJGA 1JIWP 4AUOA 1R1HA 1Y93A 3AYUA 3NX7A 5D1TA 3F15A 1G05A 1I76A 3EWJA 1IACA 2W12A 1ZP5A 4QKZA 1G49A 1KUKA 4L7AA 5I0LA 4L6TA 3O64A 1HV5A 3LJTA 1EAKA 1Y8JA 3DWBA 3TVCA 2AIGP 3HBVP 1JAQA 1IADA 1XFUA 2DW2A 2HU6A 1UEAA 4XBHA 1QUAA 1SRPA 2SRTA 1K7IA 3P24A 2D1OA 1JANA 5CXAA 3OHLA 4GQLA 1A86A 3TS4A 3DPEA 1QIBA 4AYKA 2OXZA 1RTGA 1B3DA 1K7GA 4JIJA 4Q1LA 1GE5A 1MMRA 4FU4A 3DTKA 3WV3A 3KMCA 2W13A 4DF9A 4GR0A 2X7MA 5H8XA 5BOYA 4OEIA 1CIZA 1S4BP 1BM6A 3EHYA 966CA 1HY7A 1SU3A 1YP1A 5CUHA 3E8RA 5I3MA 2DDFA 1EUBA 1CGFA 4G9LA 1GENA 3LUMA 5LABA 2X3CA 4HMAA 4H3XA 4WZVA 1FM1A 1AKLA 2KRJA 2V4BA 3V6NA 2JT6A 3LIRA 4H84A 4IN9A 2O36A 1CXVA 2OZRA 5D1SA 2MZEA 1O0TA 1D8MA 3I7IA 1Z3JA 2YUFA 1FBLA 1IABA 1MNCA 5B5OA 3HDAP 2MLRA 2OY4A 3B8ZA 1OMJA 1FLSA 3LJZA 2OW1A 1DMTA 4RT6B 4GUYA 4PKUA 1KBCA 1B8YA 4R3VA 3VTGA 2MZHA 4L63A 2O3EA 1GKDA 3HY9A 3HB2P 3ZXHA 1ND1A 1WNIA 1CGEA 1BKCI 1HFCA 1D5JA 4JP4A 3P1VA 1QICA 3B2ZA 3G5CA 2I47A 1GO8P 2W14A 2D1NA 3F19A 1YQYA 1IAGA 3GBOA 4CTHA 3K7NA 3KEKA 3LE9A 2CKIA 1JJ9A 830CA 1ROSA 2PJTA 4EFSA 2MQSA 1OM8A 1MMBA 456CA 2RJQA 4IUWA 3U1RA 3HY7A 1BUDA 1KAPP 1IAEA 1JAPA 2K9CA 5D1UA 2QPJA 4WKEA 2JT5A 4WKIA 4H49A 1JIZA 1J7NA 3AYKA 4XCTA 2MZIA 2FV5A 1AF0A 4PKSA 3KRYA 1JAOA 1QJIA 1BUVM 4PKQA 1SLNA 1OM6A 2OW9A 2POJA 4LL2A 1GXDA 3ZUKA 3WV2A 4XM8A 1GO7P 4H76A 3KEJA 5B5PA 4FXYP 2DW1A 5JMYA 1IAAA 1D7XA 2JNPA 3F18A 3G42A 2AYKA 5CZMA 2J83A 5I43A 2L0RA 3EDZA 1KUIA 2WOAA 4J4MA 3DTEA 1SATA 5BOTA 3USNA 3CKIA 1XUCA 1CGLA 4H2EA 3RTSA 1QHUA 1EB6A 3LQBA 2OW0A 4H1QA 3L0VA 2OI0A 1BIWA 1ZTQA 1HTDA 1ATLA 1SMPA 2OXWA 3AIGA 1BKCA 1OM7A 1BKCE 3DPFA 3F17A 2K2GA 5I2ZA 3KMEA 1O0QA 3LMCA 1JH1A 2JSDA 3TSKA 3ZVSA 3WV1A 4YEHA 4ZR5A 1QJJA 1XFYA 1JK3A 2YB9A 2Z2DA 1RM8A 1SLMA 1ITVA 1C7KA 3BA0A 4JQGA 2WO9A 2A8HA 4GR3A 1BSWA 3S18A 1RMZA 4DV8A 4WF6A 2USNA 4A7BA 1HOVA 2XS4A 3EDGA 4WK7A 5D7WA 4JA1A 4XM7A 3KECA 1PWWA 3MA2A 1G12A 2E2DA 2Y6CA 5L79A 3RTTA 4JPAA 2JIHA 2WO8A 1R54A 4ILWD 3F1AA 1BQQM 3LGPA 1HXNA 1JKYA 5I12A 1G4KA 5D2BA 4HSDA 1R1JA 1UMSA 4PKWA 3LILA 1UMTA 3TT4A 4AIGA 1G9KA 3DSLA 1OO9A 2YIGA 1PWUA 2RJPA 1USNA 1XFXA 3KHIA 4AXQA 3N2UA 1R55A 3V96B 4ON1A 3ELMA 1C8TA 2W0DA 5L7FA 2MLSA 4I03A 1XFWA 3KWVC 1PEXA 2N8RA 1QIAA 3HYGA 1D8FA 3LQ0A 2DDYA 4H30A 4DPEA 4DD8A 3K7LA 1CK7A 2OW2A 4GWNA 3C7XA 1YCMA 5BPAA 1UTZA 3LP9A 1AYKA 3UVCA 3F16A 1ZXCA 3DTIA 1DTHA 2J0TA 1A85A 3LK8A 1OS9A 3N2VA 1Q3AA 2W15A 2E3XA 2X3AA 1XFZA 3EDIA 1YOUA 4GF1A 2XS3A 3VI1A 4A3WA 1GE7A 5D3CA 4XM6A 2X3BA 3EDHA 2OVXA 1R1IA 1H71P 4H82A 1I73A 3Q2HA 3DNGA 3LKAA 1Y0VA 4G0DA 2EROA 2OY2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HX3 A;  2TCL A;  1XFV A;  1C3I A;  1MMP A;  3LIK A;  2ERP A;  4PKV A;  2OVZ A;  1KUF A;  1CAQ A;  3EHX A;  4IJO A;  3HBU P;  1OS2 A;  3LEA A;  4FVL A;  1HFS A;  1L6J A;  1KUG A;  3HDB A;  1PWQ A;  2CLT A;  4PKR A;  2Y6D A;  3Q2G A;  4FXQ A;  4I35 A;  3OYO A;  4L19 A;  1PWV A;  1XUD A;  3SHI A;  1CQR A;  1PWP A;  1KUH A;  2FV9 A;  2OXU A;  1MMQ A;  1ZS0 A;  1BZS A;  1UTT A;  5I4O A;  4GWM A;  1ZXV A;  4GR8 A;  4PKT A;  1QJS A;  2JXY A;  1GKC A;  2DW0 A;  3B92 A;  3DL1 A;  1GE6 A;  1K7Q A;  3I7G A;  2ERQ A;  1I1I P;  3O2X A;  1ZVX A;  1AST A;  3LUN A;  1BQO A;  3OHO A;  3L0T A;  1XUR A;  3LJG A;  1JIW P;  4AUO A;  1R1H A;  1Y93 A;  3AYU A;  3NX7 A;  5D1T A;  3F15 A;  1G05 A;  1I76 A;  3EWJ A;  1IAC A;  2W12 A;  1ZP5 A;  4QKZ A;  1G49 A;  1KUK A;  5I0L A;  4L6T A;  3O64 A;  1HV5 A;  3LJT A;  1EAK A;  1Y8J A;  3DWB A;  3TVC A;  2AIG P;  3HBV P;  1JAQ A;  1IAD A;  1XFU A;  2DW2 A;  2HU6 A;  1UEA A;  4XBH A;  1QUA A;  1SRP A;  2SRT A;  1K7I A;  3P24 A;  2D1O A;  1JAN A;  5CXA A;  3OHL A;  4GQL A;  1A86 A;  3TS4 A;  3DPE A;  1QIB A;  4AYK A;  2OXZ A;  1RTG A;  1B3D A;  1K7G A;  4JIJ A;  4Q1L A;  1GE5 A;  1MMR A;  4FU4 A;  3WV3 A;  3KMC A;  2W13 A;  4DF9 A;  4GR0 A;  2X7M A;  5H8X A;  5BOY A;  4OEI A;  1CIZ A;  1S4B P;  1BM6 A;  3EHY A;  966C A;  1HY7 A;  1SU3 A;  1YP1 A;  5CUH A;  3E8R A;  5I3M A;  2DDF A;  1EUB A;  1CGF A;  4G9L A;  1GEN A;  3LUM A;  5LAB A;  2X3C A;  4HMA A;  4H3X A;  4WZV A;  1FM1 A;  1AKL A;  2KRJ A;  2V4B A;  3V6N A;  2JT6 A;  3LIR A;  4H84 A;  4IN9 A;  2O36 A;  1CXV A;  2OZR A;  5D1S A;  2MZE A;  1O0T A;  1D8M A;  3I7I A;  1Z3J A;  1FBL A;  1IAB A;  1MNC A;  5B5O A;  3HDA P;  2MLR A;  2OY4 A;  3B8Z A;  1OMJ A;  1FLS A;  3LJZ A;  2OW1 A;  1DMT A;  4RT6 B;  4GUY A;  4PKU A;  1KBC A;  1B8Y A;  4R3V A;  3VTG A;  2MZH A;  4L63 A;  2O3E A;  1GKD A;  3HY9 A;  3HB2 P;  3ZXH A;  1ND1 A;  1WNI A;  1CGE A;  1BKC I;  1HFC A;  1D5J A;  4JP4 A;  3P1V A;  1QIC A;  3B2Z A;  3G5C A;  2I47 A;  1GO8 P;  2W14 A;  2D1N A;  3F19 A;  1YQY A;  1IAG A;  3GBO A;  4CTH A;  3K7N A;  3KEK A;  3LE9 A;  2CKI A;  1JJ9 A;  830C A;  1ROS A;  2PJT A;  4EFS A;  2MQS A;  1OM8 A;  1MMB A;  456C A;  2RJQ A;  4IUW A;  3U1R A;  3HY7 A;  1BUD A;  1KAP P;  1IAE A;  1JAP A;  2K9C A;  5D1U A;  2QPJ A;  4WKE A;  2JT5 A;  4WKI A;  4H49 A;  1JIZ A;  1J7N A;  3AYK A;  4XCT A;  2MZI A;  2FV5 A;  1AF0 A;  4PKS A;  3KRY A;  1JAO A;  1QJI A;  1BUV M;  4PKQ A;  1SLN A;  1OM6 A;  2OW9 A;  2POJ A;  4LL2 A;  1GXD A;  3ZUK A;  3WV2 A;  4XM8 A;  1GO7 P;  4H76 A;  3KEJ A;  5B5P A;  4FXY P;  2DW1 A;  5JMY A;  1IAA A;  1D7X A;  2JNP A;  3F18 A;  3G42 A;  2AYK A;  5CZM A;  2J83 A;  5I43 A;  2L0R A;  3EDZ A;  1KUI A;  2WOA A;  4J4M A;  1SAT A;  5BOT A;  3USN A;  3CKI A;  1XUC A;  1CGL A;  4H2E A;  3RTS A;  1QHU A;  1EB6 A;  3LQB A;  2OW0 A;  4H1Q A;  3L0V A;  2OI0 A;  1BIW A;  1ZTQ A;  1HTD A;  1ATL A;  1SMP A;  2OXW A;  3AIG A;  1BKC A;  1OM7 A;  1BKC E;  3DPF A;  3F17 A;  2K2G A;  5I2Z A;  3KME A;  1O0Q A;  3LMC A;  1JH1 A;  2JSD A;  3TSK A;  3ZVS A;  3WV1 A;  4YEH A;  4ZR5 A;  1QJJ A;  1XFY A;  1JK3 A;  2YB9 A;  2Z2D A;  1RM8 A;  1SLM A;  1ITV A;  1C7K A;  3BA0 A;  4JQG A;  2WO9 A;  2A8H A;  4GR3 A;  1BSW A;  3S18 A;  1RMZ A;  4DV8 A;  4WF6 A;  2USN A;  4A7B A;  1HOV A;  2XS4 A;  3EDG A;  4WK7 A;  5D7W A;  4JA1 A;  4XM7 A;  3KEC A;  1PWW A;  3MA2 A;  1G12 A;  2E2D A;  2Y6C A;  5L79 A;  3RTT A;  4JPA A;  2JIH A;  2WO8 A;  1R54 A;  4ILW D;  3F1A A;  1BQQ M;  3LGP A;  1HXN A;  1JKY A;  5I12 A;  1G4K A;  5D2B A;  4HSD A;  1R1J A;  1UMS A;  4PKW A;  3LIL A;  1UMT A;  3TT4 A;  4AIG A;  1G9K A;  3DSL A;  1OO9 A;  2YIG A;  1PWU A;  2RJP A;  1USN A;  1XFX A;  3KHI A;  4AXQ A;  3N2U A;  1R55 A;  3V96 B;  4ON1 A;  3ELM A;  1C8T A;  2W0D A;  5L7F A;  2MLS A;  4I03 A;  1XFW A;  3KWV C;  1PEX A;  2N8R A;  1QIA A;  3HYG A;  1D8F A;  3LQ0 A;  2DDY A;  4H30 A;  4DPE A;  4DD8 A;  3K7L A;  1CK7 A;  2OW2 A;  4GWN A;  3C7X A;  1YCM A;  5BPA A;  1UTZ A;  3LP9 A;  1AYK A;  3UVC A;  3F16 A;  1ZXC A;  1DTH A;  2J0T A;  1A85 A;  3LK8 A;  1OS9 A;  3N2V A;  1Q3A A;  2W15 A;  2E3X A;  2X3A A;  1XFZ A;  3EDI A;  1YOU A;  4GF1 A;  2XS3 A;  3VI1 A;  4A3W A;  1GE7 A;  5D3C A;  4XM6 A;  2X3B A;  3EDH A;  2OVX A;  1R1I A;  1H71 P;  4H82 A;  1I73 A;  3Q2H A;  3DNG A;  3LKA A;  1Y0V A;  4G0D A;  2ERO A;  2OY2 A; 
#chains in the Genus database with same CATH topology
 4HX3 A;  2TCL A;  1XFV A;  1C3I A;  1MMP A;  3LIK A;  2ERP A;  4PKV A;  2OVZ A;  1KUF A;  1CAQ A;  3EHX A;  4IJO A;  3HBU P;  1OS2 A;  3LEA A;  4FVL A;  1HFS A;  1L6J A;  1KUG A;  3HDB A;  1PWQ A;  2CLT A;  4PKR A;  2Y6D A;  3Q2G A;  4FXQ A;  4I35 A;  3OYO A;  4L19 A;  1PWV A;  1XUD A;  3SHI A;  1CQR A;  1PWP A;  1KUH A;  2FV9 A;  2OXU A;  1MMQ A;  1ZS0 A;  1BZS A;  1UTT A;  5I4O A;  4GWM A;  1ZXV A;  4GR8 A;  4PKT A;  1QJS A;  2JXY A;  1GKC A;  2DW0 A;  3B92 A;  3DL1 A;  1GE6 A;  1K7Q A;  3I7G A;  2ERQ A;  1I1I P;  3O2X A;  1ZVX A;  1AST A;  3LUN A;  1BQO A;  3OHO A;  3L0T A;  1XUR A;  3LJG A;  1JIW P;  4AUO A;  1R1H A;  1Y93 A;  3AYU A;  3NX7 A;  5D1T A;  3F15 A;  1G05 A;  1I76 A;  3EWJ A;  1IAC A;  2W12 A;  1ZP5 A;  4QKZ A;  1G49 A;  1KUK A;  4L7A A;  5I0L A;  4L6T A;  3O64 A;  1HV5 A;  3LJT A;  1EAK A;  1Y8J A;  3DWB A;  3TVC A;  2AIG P;  3HBV P;  1JAQ A;  1IAD A;  1XFU A;  2DW2 A;  2HU6 A;  1UEA A;  4XBH A;  1QUA A;  1SRP A;  2SRT A;  1K7I A;  3P24 A;  2D1O A;  1XM5 A;  1JAN A;  5CXA A;  3OHL A;  4GQL A;  1A86 A;  3TS4 A;  3DPE A;  1QIB A;  4AYK A;  2OXZ A;  1RTG A;  1B3D A;  1K7G A;  4JIJ A;  4Q1L A;  1GE5 A;  1MMR A;  4FU4 A;  3DTK A;  3WV3 A;  3KMC A;  2W13 A;  4DF9 A;  4GR0 A;  2X7M A;  5H8X A;  1TVI A;  5BOY A;  4OEI A;  1CIZ A;  1S4B P;  1BM6 A;  3EHY A;  966C A;  1HY7 A;  1SU3 A;  1YP1 A;  5CUH A;  1XAX A;  3E8R A;  5I3M A;  2DDF A;  1EUB A;  1CGF A;  4G9L A;  1GEN A;  3LUM A;  5LAB A;  2X3C A;  4HMA A;  4H3X A;  4WZV A;  1FM1 A;  1AKL A;  2KRJ A;  2V4B A;  3V6N A;  2JT6 A;  3LIR A;  4H84 A;  4IN9 A;  2O36 A;  1CXV A;  2OZR A;  5D1S A;  2MZE A;  1O0T A;  1D8M A;  3I7I A;  1Z3J A;  2YUF A;  1FBL A;  1IAB A;  1MNC A;  5B5O A;  3HDA P;  2MLR A;  2OY4 A;  3B8Z A;  1OMJ A;  1FLS A;  3LJZ A;  2OW1 A;  1DMT A;  4RT6 B;  4GUY A;  4PKU A;  1KBC A;  1B8Y A;  4R3V A;  3VTG A;  2MZH A;  4L63 A;  2O3E A;  1GKD A;  3HY9 A;  3HB2 P;  3ZXH A;  1ND1 A;  1WNI A;  1CGE A;  1BKC I;  1HFC A;  1D5J A;  4JP4 A;  3P1V A;  1QIC A;  3B2Z A;  3G5C A;  2I47 A;  1GO8 P;  2W14 A;  2D1N A;  3F19 A;  1YQY A;  1IAG A;  3GBO A;  4CTH A;  3K7N A;  3KEK A;  3LE9 A;  2CKI A;  1JJ9 A;  830C A;  1ROS A;  2PJT A;  4EFS A;  2MQS A;  1OM8 A;  1MMB A;  456C A;  2RJQ A;  4IUW A;  3U1R A;  3HY7 A;  1BUD A;  1KAP P;  1IAE A;  1JAP A;  2K9C A;  5D1U A;  2QPJ A;  4WKE A;  2JT5 A;  4WKI A;  4H49 A;  1JIZ A;  1J7N A;  3AYK A;  4XCT A;  2MZI A;  2FV5 A;  1AF0 A;  4PKS A;  3KRY A;  1JAO A;  1QJI A;  1BUV M;  4PKQ A;  1SLN A;  1OM6 A;  2OW9 A;  2POJ A;  4LL2 A;  1GXD A;  3ZUK A;  3WV2 A;  4XM8 A;  1GO7 P;  4H76 A;  3KEJ A;  5B5P A;  4FXY P;  2DW1 A;  5JMY A;  1IAA A;  1D7X A;  2JNP A;  3F18 A;  3G42 A;  2AYK A;  5CZM A;  2J83 A;  5I43 A;  2L0R A;  3EDZ A;  1KUI A;  2WOA A;  4J4M A;  3DTE A;  1SAT A;  5BOT A;  3USN A;  3CKI A;  1XUC A;  1CGL A;  4H2E A;  3RTS A;  1QHU A;  1EB6 A;  3LQB A;  2OW0 A;  4H1Q A;  3L0V A;  2OI0 A;  1BIW A;  1ZTQ A;  1HTD A;  1ATL A;  1SMP A;  2OXW A;  3AIG A;  1BKC A;  1OM7 A;  1BKC E;  3DPF A;  3F17 A;  2K2G A;  5I2Z A;  3KME A;  1O0Q A;  3LMC A;  1JH1 A;  2JSD A;  3TSK A;  3ZVS A;  3WV1 A;  4YEH A;  4ZR5 A;  1QJJ A;  1XFY A;  1JK3 A;  2YB9 A;  2Z2D A;  1RM8 A;  1SLM A;  1ITV A;  1C7K A;  3BA0 A;  4JQG A;  2WO9 A;  2A8H A;  4GR3 A;  1BSW A;  3S18 A;  1RMZ A;  4DV8 A;  4WF6 A;  2USN A;  4A7B A;  1HOV A;  2XS4 A;  3EDG A;  4WK7 A;  5D7W A;  4JA1 A;  4XM7 A;  3KEC A;  1PWW A;  3MA2 A;  1G12 A;  2E2D A;  2Y6C A;  5L79 A;  3RTT A;  4JPA A;  2JIH A;  2WO8 A;  1R54 A;  4ILW D;  3F1A A;  1BQQ M;  3LGP A;  1HXN A;  1JKY A;  5I12 A;  1G4K A;  1OZ9 A;  5D2B A;  4HSD A;  1R1J A;  1UMS A;  4PKW A;  3LIL A;  1UMT A;  3TT4 A;  4AIG A;  1G9K A;  3DSL A;  1OO9 A;  2YIG A;  1PWU A;  2RJP A;  1USN A;  1XFX A;  3KHI A;  4AXQ A;  3N2U A;  1R55 A;  3V96 B;  4ON1 A;  3ELM A;  1C8T A;  2W0D A;  5L7F A;  2MLS A;  4I03 A;  1XFW A;  3KWV C;  1PEX A;  2N8R A;  1QIA A;  3HYG A;  1D8F A;  3LQ0 A;  2DDY A;  4H30 A;  4DPE A;  4DD8 A;  3K7L A;  1CK7 A;  2OW2 A;  4GWN A;  3C7X A;  1YCM A;  5BPA A;  1UTZ A;  3LP9 A;  1AYK A;  3UVC A;  3F16 A;  1ZXC A;  3DTI A;  1DTH A;  2J0T A;  1A85 A;  3LK8 A;  1OS9 A;  3N2V A;  1Q3A A;  2W15 A;  2E3X A;  2X3A A;  1XFZ A;  3EDI A;  1YOU A;  4GF1 A;  2XS3 A;  3VI1 A;  4A3W A;  1GE7 A;  5D3C A;  4XM6 A;  2X3B A;  3EDH A;  2OVX A;  1R1I A;  1H71 P;  4H82 A;  1I73 A;  3Q2H A;  3DNG A;  3LKA A;  1Y0V A;  4G0D A;  2ERO A;  2OY2 A; 
#chains in the Genus database with same CATH homology
 4HX3 A;  2TCL A;  1XFV A;  1C3I A;  1MMP A;  3LIK A;  2ERP A;  4PKV A;  2OVZ A;  1KUF A;  1CAQ A;  3EHX A;  4IJO A;  3HBU P;  1OS2 A;  3LEA A;  4FVL A;  1HFS A;  1L6J A;  1KUG A;  3HDB A;  1PWQ A;  2CLT A;  4PKR A;  2Y6D A;  3Q2G A;  4FXQ A;  4I35 A;  3OYO A;  4L19 A;  1PWV A;  1XUD A;  3SHI A;  1CQR A;  1PWP A;  1KUH A;  2FV9 A;  2OXU A;  1MMQ A;  1ZS0 A;  1BZS A;  1UTT A;  5I4O A;  4GWM A;  1ZXV A;  4GR8 A;  4PKT A;  1QJS A;  2JXY A;  1GKC A;  2DW0 A;  3B92 A;  3DL1 A;  1GE6 A;  1K7Q A;  3I7G A;  2ERQ A;  1I1I P;  3O2X A;  1ZVX A;  1AST A;  3LUN A;  1BQO A;  3OHO A;  3L0T A;  1XUR A;  3LJG A;  1JIW P;  4AUO A;  1R1H A;  1Y93 A;  3AYU A;  3NX7 A;  5D1T A;  3F15 A;  1G05 A;  1I76 A;  3EWJ A;  1IAC A;  2W12 A;  1ZP5 A;  4QKZ A;  1G49 A;  1KUK A;  4L7A A;  5I0L A;  4L6T A;  3O64 A;  1HV5 A;  3LJT A;  1EAK A;  1Y8J A;  3DWB A;  3TVC A;  2AIG P;  3HBV P;  1JAQ A;  1IAD A;  1XFU A;  2DW2 A;  2HU6 A;  1UEA A;  4XBH A;  1QUA A;  1SRP A;  2SRT A;  1K7I A;  3P24 A;  2D1O A;  1JAN A;  5CXA A;  3OHL A;  4GQL A;  1A86 A;  3TS4 A;  3DPE A;  1QIB A;  4AYK A;  2OXZ A;  1RTG A;  1B3D A;  1K7G A;  4JIJ A;  4Q1L A;  1GE5 A;  1MMR A;  4FU4 A;  3DTK A;  3WV3 A;  3KMC A;  2W13 A;  4DF9 A;  4GR0 A;  2X7M A;  5H8X A;  5BOY A;  4OEI A;  1CIZ A;  1S4B P;  1BM6 A;  3EHY A;  966C A;  1HY7 A;  1SU3 A;  1YP1 A;  5CUH A;  3E8R A;  5I3M A;  2DDF A;  1EUB A;  1CGF A;  4G9L A;  1GEN A;  3LUM A;  5LAB A;  2X3C A;  4HMA A;  4H3X A;  4WZV A;  1FM1 A;  1AKL A;  2KRJ A;  2V4B A;  3V6N A;  2JT6 A;  3LIR A;  4H84 A;  4IN9 A;  2O36 A;  1CXV A;  2OZR A;  5D1S A;  2MZE A;  1O0T A;  1D8M A;  3I7I A;  1Z3J A;  2YUF A;  1FBL A;  1IAB A;  1MNC A;  5B5O A;  3HDA P;  2MLR A;  2OY4 A;  3B8Z A;  1OMJ A;  1FLS A;  3LJZ A;  2OW1 A;  1DMT A;  4RT6 B;  4GUY A;  4PKU A;  1KBC A;  1B8Y A;  4R3V A;  3VTG A;  2MZH A;  4L63 A;  2O3E A;  1GKD A;  3HY9 A;  3HB2 P;  3ZXH A;  1ND1 A;  1WNI A;  1CGE A;  1BKC I;  1HFC A;  1D5J A;  4JP4 A;  3P1V A;  1QIC A;  3B2Z A;  3G5C A;  2I47 A;  1GO8 P;  2W14 A;  2D1N A;  3F19 A;  1YQY A;  1IAG A;  3GBO A;  4CTH A;  3K7N A;  3KEK A;  3LE9 A;  2CKI A;  1JJ9 A;  830C A;  1ROS A;  2PJT A;  4EFS A;  2MQS A;  1OM8 A;  1MMB A;  456C A;  2RJQ A;  4IUW A;  3U1R A;  3HY7 A;  1BUD A;  1KAP P;  1IAE A;  1JAP A;  2K9C A;  5D1U A;  2QPJ A;  4WKE A;  2JT5 A;  4WKI A;  4H49 A;  1JIZ A;  1J7N A;  3AYK A;  4XCT A;  2MZI A;  2FV5 A;  1AF0 A;  4PKS A;  3KRY A;  1JAO A;  1QJI A;  1BUV M;  4PKQ A;  1SLN A;  1OM6 A;  2OW9 A;  2POJ A;  4LL2 A;  1GXD A;  3ZUK A;  3WV2 A;  4XM8 A;  1GO7 P;  4H76 A;  3KEJ A;  5B5P A;  4FXY P;  2DW1 A;  5JMY A;  1IAA A;  1D7X A;  2JNP A;  3F18 A;  3G42 A;  2AYK A;  5CZM A;  2J83 A;  5I43 A;  2L0R A;  3EDZ A;  1KUI A;  2WOA A;  4J4M A;  3DTE A;  1SAT A;  5BOT A;  3USN A;  3CKI A;  1XUC A;  1CGL A;  4H2E A;  3RTS A;  1QHU A;  1EB6 A;  3LQB A;  2OW0 A;  4H1Q A;  3L0V A;  2OI0 A;  1BIW A;  1ZTQ A;  1HTD A;  1ATL A;  1SMP A;  2OXW A;  3AIG A;  1BKC A;  1OM7 A;  1BKC E;  3DPF A;  3F17 A;  2K2G A;  5I2Z A;  3KME A;  1O0Q A;  3LMC A;  1JH1 A;  2JSD A;  3TSK A;  3ZVS A;  3WV1 A;  4YEH A;  4ZR5 A;  1QJJ A;  1XFY A;  1JK3 A;  2YB9 A;  2Z2D A;  1RM8 A;  1SLM A;  1ITV A;  1C7K A;  3BA0 A;  4JQG A;  2WO9 A;  2A8H A;  4GR3 A;  1BSW A;  3S18 A;  1RMZ A;  4DV8 A;  4WF6 A;  2USN A;  4A7B A;  1HOV A;  2XS4 A;  3EDG A;  4WK7 A;  5D7W A;  4JA1 A;  4XM7 A;  3KEC A;  1PWW A;  3MA2 A;  1G12 A;  2E2D A;  2Y6C A;  5L79 A;  3RTT A;  4JPA A;  2JIH A;  2WO8 A;  1R54 A;  4ILW D;  3F1A A;  1BQQ M;  3LGP A;  1HXN A;  1JKY A;  5I12 A;  1G4K A;  5D2B A;  4HSD A;  1R1J A;  1UMS A;  4PKW A;  3LIL A;  1UMT A;  3TT4 A;  4AIG A;  1G9K A;  3DSL A;  1OO9 A;  2YIG A;  1PWU A;  2RJP A;  1USN A;  1XFX A;  3KHI A;  4AXQ A;  3N2U A;  1R55 A;  3V96 B;  4ON1 A;  3ELM A;  1C8T A;  2W0D A;  5L7F A;  2MLS A;  4I03 A;  1XFW A;  3KWV C;  1PEX A;  2N8R A;  1QIA A;  3HYG A;  1D8F A;  3LQ0 A;  2DDY A;  4H30 A;  4DPE A;  4DD8 A;  3K7L A;  1CK7 A;  2OW2 A;  4GWN A;  3C7X A;  1YCM A;  5BPA A;  1UTZ A;  3LP9 A;  1AYK A;  3UVC A;  3F16 A;  1ZXC A;  3DTI A;  1DTH A;  2J0T A;  1A85 A;  3LK8 A;  1OS9 A;  3N2V A;  1Q3A A;  2W15 A;  2E3X A;  2X3A A;  1XFZ A;  3EDI A;  1YOU A;  4GF1 A;  2XS3 A;  3VI1 A;  4A3W A;  1GE7 A;  5D3C A;  4XM6 A;  2X3B A;  3EDH A;  2OVX A;  1R1I A;  1H71 P;  4H82 A;  1I73 A;  3Q2H A;  3DNG A;  3LKA A;  1Y0V A;  4G0D A;  2ERO A;  2OY2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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