4FW5A

Crystal structure of the lpxc in complex with 4'-bromo-n-[(2s,3r)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]biphenyl-4-carboxamide inhibitor
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
301
structure length
301
Chain Sequence
NAMIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the LpxC
rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 92
structure length 301
sequence length 301
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2012-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4fw5A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4fw5A02
4FW7A 2J65A 4MQYA 3UHMA 3P76A 1YHCA 2GO3A 4FW3A 2GO4A 3U1YA 4FW4A 4LCHA 5DRPA 4U3BA 4FW5A 4OZEA 2O3ZA 4LCFA 4FW6A 2VESA 4ISAA 5DROA 3P3EA 2IERA 3PS2A 4LCGA 4OKGA 1P42A 5DRQA 2JT2A 2IESA 4J3DA 1XXEA 3P3GA 3PS3A 1YH8A 3PS1A 4IS9A 3NZKA 5DRRA 4U3DA 3P3CA 4MDTA
chains in the Genus database with same CATH superfamily
4FW7A 1VI7A 1UEKA 4DR5I 2UUCI 1HNZE 2WNRB 5BR8I 1PKPA 4B3ME 1FI4A 4Z7YA 1E3HA 4U3BA 4FW5A 4HXZA 3OTOE 3B78A 4DPXA 2V2ZA 4IZJA 4IFDD 2LJPA 4LFCE 3Q6NA 4LOMA 4B3RE 5DNLA 4USKA 4JV5E 3PS1A 5A2QQ 5FLXQ 1PIEA 4MU3A 3GONA 3QT6A 4DV3I 1NHJA 1ZXMA 4WUDA 2BV3A 4OO1B 5BR8E 4JI5I 1Z0GA 2BA0G 4MYTA 4OO1F 4DV4I 4LF8I 4DV1I 4LFAI 4YHHI 5DNXA 3T1HE 3ZM7A 2IOPA 2V8PA 1UDOA 4JI0I 4JI2I 2IERA 2OI2A 2WNRA 5IWAE 5K36C 1P42A 4DV1E 2IESA 1N0UA 4DPUA 1N33I 2ZITA 1Z5CA 1N36E 4AIDA 1OYPA 1K47A 2PO0A 4DV7E 2UU9I 4HY1A 3PYEA 4B3TE 2V2VA 3QT7A 4DR1E 4GQUA 4DR3E 1FWKA 2JE6B 1FKAE 4P52A 5DRPA 4DR7E 1Z5AA 2E5LE 1EI1A 4FW6A 1HR0I 4DUZE 1ELOA 5GMEA 3PS2A 5C0XB 4X65E 2R3VA 2UXBE 1S4EA 2WW4A 1XXEA 4JG4A 1N36I 1MG7A 1H7UA 4DR2E 2BR2B 2BM0A 1WUUA 4DR4E 2J65A 4JI8I 4LF9I 4PRVA 1VISA 4DR2I 3L7ZB 1UDNA 3B8HA 3F0NA 4FW3A 3DD6A 2F4VI 3JAMQ 3M85D 2UXDE 4JI7I 4LF7E 4RPFA 4DV6E 3P3EA 3M6AA 4LCGA 4HYMA 4UTGA 2UXBI 4MU0A 4B3SI 2O1TA 1R6MA 3J80C 3UHMA 4LF5E 4NXNE 4N3OA 4FN5A 4DV0E 1B62A 4EMDA 5C0XA 4I3HA 1NHIA 4DV0I 5JEAA 1N34E 3CDJA 5EKWA 1XMOI 1FJGE 3OTOI 4KQVA 4FW9A 4WUCA 4IZJD 1FNMA 4IFDA 4J3DA 5L3JA 2HHHI 4OO1D 4DUYI 3QT5A 3K17A 3T1YE 4LF5I 4BA2B 4WUBA 2V34A 2HHHE 2GO3A 1RREA 2XEXA 4DV3E 5ELWA 2NN6B 4QNJA 2PNZA 4X64E 5C0XF 2ZBKB 4DPTA 4JI1E 1FJGI 4UT4A 1XNRI 3J7AG 4DV4E 4LF8E 4QNKA 4DV5I 1H73A 1Z0EA 4R1FA 5LMNE 3K85A 4OKGA 1ZXNA 2F1DA 2HFSA 3LPSA 1XHKA 4IFDF 4IZKA 1HNXI 1IBKI 3LNUA 4DXLA 2HK2A 2C37B 3CWVA 3T1HI 2VQFI 1Y60A 4IFDC 4MU1A 5K36A 2BA1D 2HK3A 1MX0A 2UUAE 2ZM6I 4JI6I 3J7AM 3PYGA 4JI1I 1NHHA 1E3PA 3V5RA 4LF4I 4DV2I 2C38B 1Z0TA 2PO0B 4DV7I 1Y4SA 2HFUA 5JEAF 1XMQI 4PU9A 1ZM4A 2PNZB 4AQYE 4LF4E 4LF9E 1HNXE 2Z5CB 3K1JA 2E5LI 2NN6E 3H1CA 2PO1B 3GCMA 3D4JA 2E1RA 3B82A 2O3ZA 2UUBE 4FWHA 5K36F 4LFBE 1Z0VA 3QT8A 4DR4I 2Z5BA 2C37A 2X7IA 2UXCI 2UUBI 5JEAC 4GKJI 1J5EI 4OX9I 1XMQE 4DPYA 4DR6I 3NZKA 4NXNI 2JEAA 4X62I 3M7ND 3P06A 1Y6ZA 2GS8A 4LF7I 1IBMI 2PO2A 2WP8B 2C39A 4DU8A 1D6TA 2HKEA 2CG9A 3ZZTA 4HACA 3PYDA 2J7KA 1USVA 2NN6A 4AM3A 2Z5CA 2NPFA 3J80Q 2JT2A 2X36A 3ZKBA 1N33E 4DUYE 5IT9Q 2JE6A 2NN6D 4OX9E 4LFCI 1YHCA 4YY3I 1OYSA 2JEBA 3B4TA 3HKMA 2PNMA 1XMOE 2Z5BB 1NZ0A 4LFAE 4YHHE 4OO1C 2HKJA 4X64I 1KIJA 3GLLA 4NBQA 2DEIA 1FWLA 5LMNI 4DUZI 1XNRE 5K36B 4JI4E 3V2UC 4USMA 1OJ4A 4JI2E 4HACB 5C0XD 4DR1I 3KRNA 4DV2E 4DPWA 2C38A 3P76A 3Q6MA 3CDIA 3HULA 3U1YA 2VQFE 4LCHA 1Z5BA 4BA1A 4X65I 2IOQA 3ZKDA 2VQEI 2PO1A 4JI0E 4JYAE 1BKNA 4FWDA 5C0XC 4JI8E 1ZM3A 3Q1QA 1YH8A 1H72C 5DRRA 1Z0BA 3J81Q 4MQYA 4JI6E 2VF3A 4GKJE 4JI7E 4OO1E 1UDSA 4DR3I 1IBLI 2JEAB 2O1WA 4FW4A 3WU5A 4BA2A 4JI3E 2AE8A 4XTJA 1IBME 4PRXA 2C39B 2VESA 4KHPI 1H7SA 5C0XE 1EA6A 3H4LA 1HR0E 2V2QA 4B3MI 1J5EE 1ZM2A 2EFGA 2UXCE 4IS9A 1PVGA 4U3DA 4IZJB 1KVKA 1HNZI 5K36D 4P7AA 2BA1G 4IFDE 4GKKI 5JEAD 4B3SE 1MU5A 1N34I 3U1KA 5A2QC 1OYRA 2JEBB 2F4VE 1RR9A 4IZKB 4ED4A 4OZEA 1RHYA 3HJCA 4JI3I 3ZZ0A 4OO1A 4DV5E 4DV6I 2O1VA 2CZ9A 1Y5YA 5DRQA 2UUCE 2Q2EB 3P3GA 2PO2B 2WP8A 4B3RI 1I94E 1R6LA 1IBKE 5JEAE 5IWAI 4JI4I 4URLA 4YY3E 1H74A 4GKKE 3J81C 4JI5E 2NN6C 4K0KE 4AIMA 2CVEA 2GO4A 3GMEA 1A6FA 1Y4UA 2UUAI 5FWKA 1B63A 2NN6F 3PYFA 3ZZUA 2A2DA 5IT9C 4JV5I 4X66E 4K0KI 1N32I 1HNWE 2UU9E 4NXME 1Z0CA 2BM1A 5K36E 1ZM9A 1KTVA 4M1KA 2Z5EA 1I94I 4DU7A 4LF6E 3T1YI 2BA0D 1KKHA 2ZM6E 4LPFA 1S16A 4LF6I 2BR2A 4IFDB 1N0VC 1QZRA 1Z0WA 4DR7I 4B3TI 5LMUE 3WU4A 3M7NG 4LFBI 4X66I 1N32E 1HNWI 4JYAI 5DROA 2CGEA 4ISAA 4NXMI 5LMUI 2VQEE 5GMDA 1HK7A 3JAMC 3PS3A 2GQ0A 2DEJA 4KHPE 3P3CA 1USUA 1UDQA 4BA1B 5FLXC 4MU4A 4AQYI 4ZVIA 4Z7CA 1IBLE 1XNQE 3LTOA 3WU6A 4FWGA 3M85G 3PRYA 1XNQI 4MYUA 5EL9A 4LCFA 1DARA 2UXDI 4DR6E 5LL6R 4X62E 2R42A 3WU3A 4DR5E 2A2CA 5JEAB 3L7ZA 1Z59A 2AJ4A 1U2RA 2O1UA 2PNLA 4MDTA
chains in the Genus database with same CATH topology
4FW7A 2J65A 4MQYA 3UHMA 3P76A 1YHCA 2GO3A 4FW3A 2GO4A 3U1YA 4FW4A 4LCHA 5DRPA 4U3BA 4FW5A 4OZEA 2O3ZA 4LCFA 4FW6A 2VESA 4ISAA 5DROA 3P3EA 2IERA 3PS2A 4LCGA 4OKGA 1P42A 5DRQA 2JT2A 2IESA 4J3DA 1XXEA 3P3GA 3PS3A 1YH8A 3PS1A 4IS9A 3NZKA 5DRRA 4U3DA 3P3CA 4MDTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FW7 A;  2J65 A;  4MQY A;  3UHM A;  3P76 A;  1YHC A;  2GO3 A;  4FW3 A;  2GO4 A;  3U1Y A;  4FW4 A;  4LCH A;  5DRP A;  4U3B A;  4FW5 A;  4OZE A;  2O3Z A;  4LCF A;  4FW6 A;  2VES A;  4ISA A;  5DRO A;  3P3E A;  2IER A;  3PS2 A;  4LCG A;  4OKG A;  1P42 A;  5DRQ A;  2JT2 A;  2IES A;  4J3D A;  1XXE A;  3P3G A;  3PS3 A;  1YH8 A;  3PS1 A;  4IS9 A;  3NZK A;  5DRR A;  4U3D A;  3P3C A;  4MDT A; 
#chains in the Genus database with same CATH topology
 4FW7 A;  1VI7 A;  1UEK A;  4DR5 I;  2UUC I;  1HNZ E;  2WNR B;  5BR8 I;  1PKP A;  4B3M E;  1FI4 A;  4Z7Y A;  1E3H A;  4U3B A;  4FW5 A;  4HXZ A;  3OTO E;  3B78 A;  4DPX A;  2V2Z A;  4IZJ A;  4IFD D;  2LJP A;  4LFC E;  3Q6N A;  4LOM A;  4B3R E;  5DNL A;  4USK A;  4JV5 E;  3PS1 A;  5A2Q Q;  5FLX Q;  1PIE A;  4MU3 A;  3GON A;  3QT6 A;  4DV3 I;  1NHJ A;  1ZXM A;  4WUD A;  2BV3 A;  4OO1 B;  5BR8 E;  4JI5 I;  1Z0G A;  2BA0 G;  4MYT A;  4OO1 F;  4DV4 I;  4LF8 I;  4DV1 I;  4LFA I;  4YHH I;  5DNX A;  3T1H E;  3ZM7 A;  2IOP A;  2V8P A;  1UDO A;  4JI0 I;  4JI2 I;  2IER A;  2OI2 A;  2WNR A;  5IWA E;  5K36 C;  1P42 A;  4DV1 E;  2IES A;  1N0U A;  4DPU A;  1N33 I;  2ZIT A;  1Z5C A;  1N36 E;  4AID A;  1OYP A;  1K47 A;  2PO0 A;  4DV7 E;  2UU9 I;  4HY1 A;  3PYE A;  4B3T E;  2V2V A;  3QT7 A;  4DR1 E;  4GQU A;  4DR3 E;  1FWK A;  2JE6 B;  1FKA E;  4P52 A;  5DRP A;  4DR7 E;  1Z5A A;  2E5L E;  1EI1 A;  4FW6 A;  1HR0 I;  4DUZ E;  1ELO A;  5GME A;  3PS2 A;  5C0X B;  4X65 E;  2R3V A;  2UXB E;  1S4E A;  2WW4 A;  1XXE A;  4JG4 A;  1N36 I;  1MG7 A;  1H7U A;  4DR2 E;  2BR2 B;  2BM0 A;  1WUU A;  4DR4 E;  2J65 A;  4JI8 I;  4LF9 I;  4PRV A;  1VIS A;  4DR2 I;  3L7Z B;  1UDN A;  3B8H A;  3F0N A;  4FW3 A;  3DD6 A;  2F4V I;  3JAM Q;  3M85 D;  2UXD E;  4JI7 I;  4LF7 E;  4RPF A;  4DV6 E;  3P3E A;  3M6A A;  4LCG A;  4HYM A;  4UTG A;  2UXB I;  4MU0 A;  4B3S I;  2O1T A;  1R6M A;  3J80 C;  3UHM A;  4LF5 E;  4NXN E;  4N3O A;  4FN5 A;  4DV0 E;  1B62 A;  4EMD A;  5C0X A;  4I3H A;  1NHI A;  4DV0 I;  5JEA A;  1N34 E;  3CDJ A;  5EKW A;  1XMO I;  1FJG E;  3OTO I;  4KQV A;  4FW9 A;  4WUC A;  4IZJ D;  1FNM A;  4IFD A;  4J3D A;  5L3J A;  2HHH I;  4OO1 D;  4DUY I;  3QT5 A;  3K17 A;  3T1Y E;  4LF5 I;  4BA2 B;  4WUB A;  2V34 A;  2HHH E;  2GO3 A;  1RRE A;  2XEX A;  4DV3 E;  5ELW A;  2NN6 B;  4QNJ A;  2PNZ A;  4X64 E;  5C0X F;  2ZBK B;  4DPT A;  4JI1 E;  1FJG I;  4UT4 A;  1XNR I;  3J7A G;  4DV4 E;  4LF8 E;  4QNK A;  4DV5 I;  1H73 A;  1Z0E A;  4R1F A;  5LMN E;  3K85 A;  4OKG A;  1ZXN A;  2F1D A;  2HFS A;  3LPS A;  1XHK A;  4IFD F;  4IZK A;  1HNX I;  1IBK I;  3LNU A;  4DXL A;  2HK2 A;  2C37 B;  3CWV A;  3T1H I;  2VQF I;  1Y60 A;  4IFD C;  4MU1 A;  5K36 A;  2BA1 D;  2HK3 A;  1MX0 A;  2UUA E;  2ZM6 I;  4JI6 I;  3J7A M;  3PYG A;  4JI1 I;  1NHH A;  1E3P A;  3V5R A;  4LF4 I;  4DV2 I;  2C38 B;  1Z0T A;  2PO0 B;  4DV7 I;  1Y4S A;  2HFU A;  5JEA F;  1XMQ I;  4PU9 A;  1ZM4 A;  2PNZ B;  4AQY E;  4LF4 E;  4LF9 E;  1HNX E;  2Z5C B;  3K1J A;  2E5L I;  2NN6 E;  3H1C A;  2PO1 B;  3GCM A;  3D4J A;  2E1R A;  3B82 A;  2O3Z A;  2UUB E;  4FWH A;  5K36 F;  4LFB E;  1Z0V A;  3QT8 A;  4DR4 I;  2Z5B A;  2C37 A;  2X7I A;  2UXC I;  2UUB I;  5JEA C;  4GKJ I;  1J5E I;  4OX9 I;  1XMQ E;  4DPY A;  4DR6 I;  3NZK A;  4NXN I;  2JEA A;  4X62 I;  3M7N D;  3P06 A;  1Y6Z A;  2GS8 A;  4LF7 I;  1IBM I;  2PO2 A;  2WP8 B;  2C39 A;  4DU8 A;  1D6T A;  2HKE A;  2CG9 A;  3ZZT A;  4HAC A;  3PYD A;  2J7K A;  1USV A;  2NN6 A;  4AM3 A;  2Z5C A;  2NPF A;  3J80 Q;  2JT2 A;  2X36 A;  3ZKB A;  1N33 E;  4DUY E;  5IT9 Q;  2JE6 A;  2NN6 D;  4OX9 E;  4LFC I;  1YHC A;  4YY3 I;  1OYS A;  2JEB A;  3B4T A;  3HKM A;  2PNM A;  1XMO E;  2Z5B B;  1NZ0 A;  4LFA E;  4YHH E;  4OO1 C;  2HKJ A;  4X64 I;  1KIJ A;  3GLL A;  4NBQ A;  2DEI A;  1FWL A;  5LMN I;  4DUZ I;  1XNR E;  5K36 B;  4JI4 E;  3V2U C;  4USM A;  1OJ4 A;  4JI2 E;  4HAC B;  5C0X D;  4DR1 I;  3KRN A;  4DV2 E;  4DPW A;  2C38 A;  3P76 A;  3Q6M A;  3CDI A;  3HUL A;  3U1Y A;  2VQF E;  4LCH A;  1Z5B A;  4BA1 A;  4X65 I;  2IOQ A;  3ZKD A;  2VQE I;  2PO1 A;  4JI0 E;  4JYA E;  1BKN A;  4FWD A;  5C0X C;  4JI8 E;  1ZM3 A;  3Q1Q A;  1YH8 A;  1H72 C;  5DRR A;  1Z0B A;  3J81 Q;  4MQY A;  4JI6 E;  2VF3 A;  4GKJ E;  4JI7 E;  4OO1 E;  1UDS A;  4DR3 I;  1IBL I;  2JEA B;  2O1W A;  4FW4 A;  3WU5 A;  4BA2 A;  4JI3 E;  2AE8 A;  4XTJ A;  1IBM E;  4PRX A;  2C39 B;  2VES A;  4KHP I;  1H7S A;  5C0X E;  1EA6 A;  3H4L A;  1HR0 E;  2V2Q A;  4B3M I;  1J5E E;  1ZM2 A;  2EFG A;  2UXC E;  4IS9 A;  1PVG A;  4U3D A;  4IZJ B;  1KVK A;  1HNZ I;  5K36 D;  4P7A A;  2BA1 G;  4IFD E;  4GKK I;  5JEA D;  4B3S E;  1MU5 A;  1N34 I;  3U1K A;  5A2Q C;  1OYR A;  2JEB B;  2F4V E;  1RR9 A;  4IZK B;  4ED4 A;  4OZE A;  1RHY A;  3HJC A;  4JI3 I;  3ZZ0 A;  4OO1 A;  4DV5 E;  4DV6 I;  2O1V A;  2CZ9 A;  1Y5Y A;  5DRQ A;  2UUC E;  2Q2E B;  3P3G A;  2PO2 B;  2WP8 A;  4B3R I;  1I94 E;  1R6L A;  1IBK E;  5JEA E;  5IWA I;  4JI4 I;  4URL A;  4YY3 E;  1H74 A;  4GKK E;  3J81 C;  4JI5 E;  2NN6 C;  4K0K E;  4AIM A;  2CVE A;  2GO4 A;  3GME A;  1A6F A;  1Y4U A;  2UUA I;  5FWK A;  1B63 A;  2NN6 F;  3PYF A;  3ZZU A;  2A2D A;  5IT9 C;  4JV5 I;  4X66 E;  4K0K I;  1N32 I;  1HNW E;  2UU9 E;  4NXM E;  1Z0C A;  2BM1 A;  5K36 E;  1ZM9 A;  1KTV A;  4M1K A;  2Z5E A;  1I94 I;  4DU7 A;  4LF6 E;  3T1Y I;  2BA0 D;  1KKH A;  2ZM6 E;  4LPF A;  1S16 A;  4LF6 I;  2BR2 A;  4IFD B;  1N0V C;  1QZR A;  1Z0W A;  4DR7 I;  4B3T I;  5LMU E;  3WU4 A;  3M7N G;  4LFB I;  4X66 I;  1N32 E;  1HNW I;  4JYA I;  5DRO A;  2CGE A;  4ISA A;  4NXM I;  5LMU I;  2VQE E;  5GMD A;  1HK7 A;  3JAM C;  3PS3 A;  2GQ0 A;  2DEJ A;  4KHP E;  3P3C A;  1USU A;  1UDQ A;  4BA1 B;  5FLX C;  4MU4 A;  4AQY I;  4ZVI A;  4Z7C A;  1IBL E;  1XNQ E;  3LTO A;  3WU6 A;  4FWG A;  3M85 G;  3PRY A;  1XNQ I;  4MYU A;  5EL9 A;  4LCF A;  1DAR A;  2UXD I;  4DR6 E;  5LL6 R;  4X62 E;  2R42 A;  3WU3 A;  4DR5 E;  2A2C A;  5JEA B;  3L7Z A;  1Z59 A;  2AJ4 A;  1U2R A;  2O1U A;  2PNL A;  4MDT A; 
#chains in the Genus database with same CATH homology
 4FW7 A;  2J65 A;  4MQY A;  3UHM A;  3P76 A;  1YHC A;  2GO3 A;  4FW3 A;  2GO4 A;  3U1Y A;  4FW4 A;  4LCH A;  5DRP A;  4U3B A;  4FW5 A;  4OZE A;  2O3Z A;  4LCF A;  4FW6 A;  2VES A;  4ISA A;  5DRO A;  3P3E A;  2IER A;  3PS2 A;  4LCG A;  4OKG A;  1P42 A;  5DRQ A;  2JT2 A;  2IES A;  4J3D A;  1XXE A;  3P3G A;  3PS3 A;  1YH8 A;  3PS1 A;  4IS9 A;  3NZK A;  5DRR A;  4U3D A;  3P3C A;  4MDT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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