4FW5A

Crystal structure of the lpxc in complex with 4'-bromo-n-[(2s,3r)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]biphenyl-4-carboxamide inhibitor
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
301
structure length
301
Chain Sequence
NAMIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Crystal Structure of the LpxC
rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase/hydrolase inhibitor
total genus 92
structure length 301
sequence length 301
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2012-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4fw5A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4fw5A02
3UHMA 4LCGA 3P3CA 3PS1A 4OKGA 4FW5A 1P42A 4LCFA 5DRRA 3P3EA 4MQYA 4IS9A 4U3BA 3U1YA 5DRPA 4FW3A 5DROA 2GO3A 4U3DA 3NZKA 4MDTA 1YH8A 2GO4A 4OZEA 2VESA 4J3DA 2O3ZA 5DRQA 4FW7A 3PS3A 3P76A 4LCHA 1XXEA 2J65A 3P3GA 4FW4A 1YHCA 2IESA 2IERA 4FW6A 4ISAA 2JT2A 3PS2A
chains in the Genus database with same CATH superfamily
1H74A 2CZ9A 3QT6A 4URLA 3P3CA 1Y4UA 2BA1G 4HXZA 2HFUA 1WUUA 1ZXMA 4JI0I 1HNWI 2R42A 5DRPA 1NZ0A 4FW3A 2Z5CA 5LMNE 3K85A 4JI2I 2UXCE 3Q1QA 4P7AA 1IBLI 2WP8A 2PO2B 1XNQE 3H4LA 3WU6A 2VF3A 1P42A 1Z0VA 4YY3E 3P3EA 4HY1A 1I94E 4DR3E 3K17A 4IZJA 1NHIA 3M85D 3CWVA 4DPXA 4AQYE 4XTJA 4LF7E 4JI8I 4JI6E 2GO4A 4DV5I 2VESA 4M1KA 2UU9I 2HFSA 5C0XD 4DR4I 5ELWA 2CG9A 4USKA 4DV3I 1H7UA 4JI7E 1ZM9A 4NXNE 2C39B 1UDNA 2VQEI 3ZM7A 4MU1A 2IERA 4JYAI 3T1HE 5C0XC 2F4VE 1N33E 3DD6A 1RR9A 1UDQA 2HKJA 3WU4A 1OJ4A 4LCGA 5EKWA 4X62E 3F0NA 4FWGA 2ZM6E 3PYEA 1N32E 4MYTA 1R6MA 4DR6E 3U1YA 1N34I 2C38A 4X64I 2VQFE 4HYMA 4DUZE 2BM0A 5A2QC 5FWKA 5BR8E 3J80Q 1QZRA 4FW7A 1RHYA 3P76A 4X65E 2JE6A 1XXEA 1FI4A 4LF4E 3GLLA 4HACA 4JI1E 4OX9I 3PS2A 3CDJA 1ZXNA 3Q6MA 5LMUE 2UUCI 2X7IA 2BM1A 4DUYI 5FLXQ 3U1KA 2OI2A 1XNRI 3B78A 1FJGI 2PNLA 4MU3A 2BA0G 4LF6E 3ZKDA 4DU8A 1XHKA 4U3DA 2J7KA 4MU4A 4LFCE 2UXDI 4Z7YA 5K36D 2PO2A 1N0VC 4OO1D 4NBQA 5IT9Q 4X66E 2O1VA 2BV3A 1RREA 4I3HA 5K36C 3LTOA 1S4EA 3WU3A 4R1FA 5JEAD 2UXBE 4OKGA 5LMNI 1HNZE 4OO1C 4QNKA 3J80C 5C0XB 2HHHE 1Y6ZA 5JEAC 1XNQI 1UDOA 1NHJA 3LPSA 4B3TE 1IBMI 4MYUA 4GQUA 2C39A 2JEBB 3QT7A 4LFAE 5LL6R 2Z5BB 2UUAI 5FLXC 4YY3I 4B3ME 1N36E 1R6LA 1Z0BA 4DR3I 1I94I 3PYGA 4FWHA 1UDSA 4AQYI 4FW9A 4LF7I 4NXMI 4B3SE 4P52A 4U3BA 5K36E 2EFGA 4NXNI 4K0KE 4OO1E 2A2DA 1OYRA 1J5EE 1YH8A 1IBKE 4LF9E 5IT9C 4RPFA 2NN6B 4EMDA 1Z0CA 4LF8E 2F4VI 3M7NG 5JEAE 1Z0GA 2ZM6I 1N32I 2C37B 2LJPA 4JI3I 4IFDB 3QT8A 1H73A 4DUZI 2VQFI 1ZM3A 4LOMA 1UEKA 2Q2EB 5IWAI 4BA2B 2GQ0A 4DV2E 4DR7E 2WNRB 5DRRA 3JAMQ 4GKKE 5BR8I 1FWLA 3B82A 1S16A 4X65I 2AJ4A 1VI7A 3ZZUA 4DV7E 4IZJD 4JI1I 1D6TA 1KKHA 4DR5E 1PIEA 3WU5A 1B62A 2AE8A 2UUBE 3OTOI 4LF6I 4DV6E 4KQVA 1PVGA 3ZKBA 4QNJA 4LFCI 5C0XA 4PRVA 1HNWE 4PU9A 3CDIA 2O3ZA 2NN6F 5DRQA 1PKPA 1A6FA 2JEBA 2PNMA 4LCHA 1XMOI 2Z5BA 2UXBI 1YHCA 4UTGA 3JAMC 2NPFA 2IOPA 2JT2A 4DR1E 4IFDF 2V34A 2HHHI 2X36A 4JV5E 1E3PA 2BA1D 2CVEA 4MQYA 4B3TI 1FNMA 2CGEA 2BR2B 5DROA 4LFAI 3L7ZB 4DV1I 4USMA 4B3MI 4JI5E 2NN6A 1N36I 3M7ND 2E5LE 3PYFA 3V2UC 3Q6NA 4DV4E 2C37A 3J81Q 2V8PA 2UU9E 3V5RA 4DR4E 4IFDA 4DPTA 1NHHA 1USUA 2VQEE 1XMQE 4BA2A 1ZM2A 3GONA 2WNRA 4K0KI 3HJCA 2E1RA 1J5EI 1IBKI 1U2RA 4IS9A 1Z59A 2UXCI 4LF5E 4LF8I 3B8HA 2DEJA 3PRYA 1EA6A 3PYDA 4DR2E 2F1DA 4B3RE 4MDTA 4ZVIA 4ED4A 4DV2I 4DR7I 4FW4A 4KHPE 2O1WA 4FW6A 3J7AG 1FKAE 1Y4SA 3PS1A 4OX9E 4DV7I 4JI6I 4PRXA 4N3OA 4WUDA 2V2QA 1HR0E 1Z0WA 4JI7I 4DUYE 3P06A 2GO3A 1HNXE 3J81C 5DNXA 1XNRE 4FN5A 3T1HI 2XEXA 1N33I 2UUBI 4WUCA 1Y5YA 4X62I 4JI4E 4YHHE 4BA1B 4DR6I 3UHMA 4GKJE 1H7SA 4DV0E 1OYPA 3GCMA 2PNZB 1Z0TA 4LFBE 4AM3A 2BR2A 2HK3A 1HK7A 5C0XF 2BA0D 3L7ZA 3B4TA 5K36B 3QT5A 1BKNA 5L3JA 3KRNA 4OO1B 4LF4I 4DR1I 3PS3A 5GMDA 5A2QQ 5LMUI 4IZKB 5JEAB 4JV5I 1IBME 2GS8A 2HKEA 3T1YE 5DNLA 2UUAE 2PO1B 2A2CA 4LCFA 2JEAB 4JI5I 1VISA 2E5LI 4DPUA 4NXME 3J7AM 4AIMA 3HULA 3NZKA 4DV4I 1E3HA 4J3DA 4JI0E 1DARA 2PO0B 4X66I 3D4JA 1ELOA 3M6AA 4DPYA 4FWDA 4Z7CA 1XMQI 2V2VA 4JI2E 2J65A 5GMEA 2O1UA 1HNZI 4DXLA 1KTVA 1IBLE 4ISAA 4LF5I 1N0UA 2HK2A 2ZBKB 4DR2I 1KVKA 4B3RI 4JI3E 3HKMA 4DPWA 5IWAE 2Z5CB 5K36F 4KHPI 3ZZTA 4OO1F 3H1CA 2WP8B 2Z5EA 1Y60A 1KIJA 4JI8E 1H72C 2NN6D 5JEAF 4DV5E 4B3SI 2ZITA 4BA1A 4DV3E 2R3VA 1HR0I 4FW5A 1ZM4A 2NN6C 2PNZA 1HNXI 5C0XE 4JYAE 2O1TA 4UT4A 4IFDD 4MU0A 1K47A 4LF9I 3OTOE 4IZJB 3M85G 4DU7A 1EI1A 2DEIA 5K36A 4AIDA 3GMEA 4IFDC 4JI4I 4OO1A 1N34E 4X64E 4YHHI 5EL9A 4GKJI 4IZKA 5JEAA 4DV0I 1OYSA 2IESA 4LFBI 4GKKI 1Z5AA 1B63A 1Z5CA 1Z5BA 1XMOE 2V2ZA 4JG4A 2PO1A 2JEAA 1MG7A 1Z0EA 2WW4A 2C38B 1USVA 2UUCE 4DR5I 2NN6E 4OZEA 3K1JA 4LPFA 2PO0A 1MU5A 3T1YI 1FJGE 4DV1E 2JE6B 1FWKA 1MX0A 3P3GA 3ZZ0A 4DV6I 2IOQA 4IFDE 4HACB 2UXDE 3LNUA 4WUBA
chains in the Genus database with same CATH topology
3UHMA 4LCGA 3P3CA 3PS1A 4OKGA 4FW5A 1P42A 4LCFA 5DRRA 3P3EA 4MQYA 4IS9A 4U3BA 3U1YA 5DRPA 4FW3A 5DROA 2GO3A 4U3DA 3NZKA 4MDTA 1YH8A 2GO4A 4OZEA 2VESA 4J3DA 2O3ZA 5DRQA 4FW7A 3PS3A 3P76A 4LCHA 1XXEA 2J65A 3P3GA 4FW4A 1YHCA 2IESA 2IERA 4FW6A 4ISAA 2JT2A 3PS2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UHM A;  4LCG A;  3P3C A;  3PS1 A;  4OKG A;  4FW5 A;  1P42 A;  4LCF A;  5DRR A;  3P3E A;  4MQY A;  4IS9 A;  4U3B A;  3U1Y A;  5DRP A;  4FW3 A;  5DRO A;  2GO3 A;  4U3D A;  3NZK A;  4MDT A;  1YH8 A;  2GO4 A;  4OZE A;  2VES A;  4J3D A;  2O3Z A;  5DRQ A;  4FW7 A;  3PS3 A;  3P76 A;  4LCH A;  1XXE A;  2J65 A;  3P3G A;  4FW4 A;  1YHC A;  2IES A;  2IER A;  4FW6 A;  4ISA A;  2JT2 A;  3PS2 A; 
#chains in the Genus database with same CATH topology
 1H74 A;  2CZ9 A;  3QT6 A;  4URL A;  3P3C A;  1Y4U A;  2BA1 G;  4HXZ A;  2HFU A;  1WUU A;  1ZXM A;  4JI0 I;  1HNW I;  2R42 A;  5DRP A;  1NZ0 A;  4FW3 A;  2Z5C A;  5LMN E;  3K85 A;  4JI2 I;  2UXC E;  3Q1Q A;  4P7A A;  1IBL I;  2WP8 A;  2PO2 B;  1XNQ E;  3H4L A;  3WU6 A;  2VF3 A;  1P42 A;  1Z0V A;  4YY3 E;  3P3E A;  4HY1 A;  1I94 E;  4DR3 E;  3K17 A;  4IZJ A;  1NHI A;  3M85 D;  3CWV A;  4DPX A;  4AQY E;  4XTJ A;  4LF7 E;  4JI8 I;  4JI6 E;  2GO4 A;  4DV5 I;  2VES A;  4M1K A;  2UU9 I;  2HFS A;  5C0X D;  4DR4 I;  5ELW A;  2CG9 A;  4USK A;  4DV3 I;  1H7U A;  4JI7 E;  1ZM9 A;  4NXN E;  2C39 B;  1UDN A;  2VQE I;  3ZM7 A;  4MU1 A;  2IER A;  4JYA I;  3T1H E;  5C0X C;  2F4V E;  1N33 E;  3DD6 A;  1RR9 A;  1UDQ A;  2HKJ A;  3WU4 A;  1OJ4 A;  4LCG A;  5EKW A;  4X62 E;  3F0N A;  4FWG A;  2ZM6 E;  3PYE A;  1N32 E;  4MYT A;  1R6M A;  4DR6 E;  3U1Y A;  1N34 I;  2C38 A;  4X64 I;  2VQF E;  4HYM A;  4DUZ E;  2BM0 A;  5A2Q C;  5FWK A;  5BR8 E;  3J80 Q;  1QZR A;  4FW7 A;  1RHY A;  3P76 A;  4X65 E;  2JE6 A;  1XXE A;  1FI4 A;  4LF4 E;  3GLL A;  4HAC A;  4JI1 E;  4OX9 I;  3PS2 A;  3CDJ A;  1ZXN A;  3Q6M A;  5LMU E;  2UUC I;  2X7I A;  2BM1 A;  4DUY I;  5FLX Q;  3U1K A;  2OI2 A;  1XNR I;  3B78 A;  1FJG I;  2PNL A;  4MU3 A;  2BA0 G;  4LF6 E;  3ZKD A;  4DU8 A;  1XHK A;  4U3D A;  2J7K A;  4MU4 A;  4LFC E;  2UXD I;  4Z7Y A;  5K36 D;  2PO2 A;  1N0V C;  4OO1 D;  4NBQ A;  5IT9 Q;  4X66 E;  2O1V A;  2BV3 A;  1RRE A;  4I3H A;  5K36 C;  3LTO A;  1S4E A;  3WU3 A;  4R1F A;  5JEA D;  2UXB E;  4OKG A;  5LMN I;  1HNZ E;  4OO1 C;  4QNK A;  3J80 C;  5C0X B;  2HHH E;  1Y6Z A;  5JEA C;  1XNQ I;  1UDO A;  1NHJ A;  3LPS A;  4B3T E;  1IBM I;  4MYU A;  4GQU A;  2C39 A;  2JEB B;  3QT7 A;  4LFA E;  5LL6 R;  2Z5B B;  2UUA I;  5FLX C;  4YY3 I;  4B3M E;  1N36 E;  1R6L A;  1Z0B A;  4DR3 I;  1I94 I;  3PYG A;  4FWH A;  1UDS A;  4AQY I;  4FW9 A;  4LF7 I;  4NXM I;  4B3S E;  4P52 A;  4U3B A;  5K36 E;  2EFG A;  4NXN I;  4K0K E;  4OO1 E;  2A2D A;  1OYR A;  1J5E E;  1YH8 A;  1IBK E;  4LF9 E;  5IT9 C;  4RPF A;  2NN6 B;  4EMD A;  1Z0C A;  4LF8 E;  2F4V I;  3M7N G;  5JEA E;  1Z0G A;  2ZM6 I;  1N32 I;  2C37 B;  2LJP A;  4JI3 I;  4IFD B;  3QT8 A;  1H73 A;  4DUZ I;  2VQF I;  1ZM3 A;  4LOM A;  1UEK A;  2Q2E B;  5IWA I;  4BA2 B;  2GQ0 A;  4DV2 E;  4DR7 E;  2WNR B;  5DRR A;  3JAM Q;  4GKK E;  5BR8 I;  1FWL A;  3B82 A;  1S16 A;  4X65 I;  2AJ4 A;  1VI7 A;  3ZZU A;  4DV7 E;  4IZJ D;  4JI1 I;  1D6T A;  1KKH A;  4DR5 E;  1PIE A;  3WU5 A;  1B62 A;  2AE8 A;  2UUB E;  3OTO I;  4LF6 I;  4DV6 E;  4KQV A;  1PVG A;  3ZKB A;  4QNJ A;  4LFC I;  5C0X A;  4PRV A;  1HNW E;  4PU9 A;  3CDI A;  2O3Z A;  2NN6 F;  5DRQ A;  1PKP A;  1A6F A;  2JEB A;  2PNM A;  4LCH A;  1XMO I;  2Z5B A;  2UXB I;  1YHC A;  4UTG A;  3JAM C;  2NPF A;  2IOP A;  2JT2 A;  4DR1 E;  4IFD F;  2V34 A;  2HHH I;  2X36 A;  4JV5 E;  1E3P A;  2BA1 D;  2CVE A;  4MQY A;  4B3T I;  1FNM A;  2CGE A;  2BR2 B;  5DRO A;  4LFA I;  3L7Z B;  4DV1 I;  4USM A;  4B3M I;  4JI5 E;  2NN6 A;  1N36 I;  3M7N D;  2E5L E;  3PYF A;  3V2U C;  3Q6N A;  4DV4 E;  2C37 A;  3J81 Q;  2V8P A;  2UU9 E;  3V5R A;  4DR4 E;  4IFD A;  4DPT A;  1NHH A;  1USU A;  2VQE E;  1XMQ E;  4BA2 A;  1ZM2 A;  3GON A;  2WNR A;  4K0K I;  3HJC A;  2E1R A;  1J5E I;  1IBK I;  1U2R A;  4IS9 A;  1Z59 A;  2UXC I;  4LF5 E;  4LF8 I;  3B8H A;  2DEJ A;  3PRY A;  1EA6 A;  3PYD A;  4DR2 E;  2F1D A;  4B3R E;  4MDT A;  4ZVI A;  4ED4 A;  4DV2 I;  4DR7 I;  4FW4 A;  4KHP E;  2O1W A;  4FW6 A;  3J7A G;  1FKA E;  1Y4S A;  3PS1 A;  4OX9 E;  4DV7 I;  4JI6 I;  4PRX A;  4N3O A;  4WUD A;  2V2Q A;  1HR0 E;  1Z0W A;  4JI7 I;  4DUY E;  3P06 A;  2GO3 A;  1HNX E;  3J81 C;  5DNX A;  1XNR E;  4FN5 A;  3T1H I;  2XEX A;  1N33 I;  2UUB I;  4WUC A;  1Y5Y A;  4X62 I;  4JI4 E;  4YHH E;  4BA1 B;  4DR6 I;  3UHM A;  4GKJ E;  1H7S A;  4DV0 E;  1OYP A;  3GCM A;  2PNZ B;  1Z0T A;  4LFB E;  4AM3 A;  2BR2 A;  2HK3 A;  1HK7 A;  5C0X F;  2BA0 D;  3L7Z A;  3B4T A;  5K36 B;  3QT5 A;  1BKN A;  5L3J A;  3KRN A;  4OO1 B;  4LF4 I;  4DR1 I;  3PS3 A;  5GMD A;  5A2Q Q;  5LMU I;  4IZK B;  5JEA B;  4JV5 I;  1IBM E;  2GS8 A;  2HKE A;  3T1Y E;  5DNL A;  2UUA E;  2PO1 B;  2A2C A;  4LCF A;  2JEA B;  4JI5 I;  1VIS A;  2E5L I;  4DPU A;  4NXM E;  3J7A M;  4AIM A;  3HUL A;  3NZK A;  4DV4 I;  1E3H A;  4J3D A;  4JI0 E;  1DAR A;  2PO0 B;  4X66 I;  3D4J A;  1ELO A;  3M6A A;  4DPY A;  4FWD A;  4Z7C A;  1XMQ I;  2V2V A;  4JI2 E;  2J65 A;  5GME A;  2O1U A;  1HNZ I;  4DXL A;  1KTV A;  1IBL E;  4ISA A;  4LF5 I;  1N0U A;  2HK2 A;  2ZBK B;  4DR2 I;  1KVK A;  4B3R I;  4JI3 E;  3HKM A;  4DPW A;  5IWA E;  2Z5C B;  5K36 F;  4KHP I;  3ZZT A;  4OO1 F;  3H1C A;  2WP8 B;  2Z5E A;  1Y60 A;  1KIJ A;  4JI8 E;  1H72 C;  2NN6 D;  5JEA F;  4DV5 E;  4B3S I;  2ZIT A;  4BA1 A;  4DV3 E;  2R3V A;  1HR0 I;  4FW5 A;  1ZM4 A;  2NN6 C;  2PNZ A;  1HNX I;  5C0X E;  4JYA E;  2O1T A;  4UT4 A;  4IFD D;  4MU0 A;  1K47 A;  4LF9 I;  3OTO E;  4IZJ B;  3M85 G;  4DU7 A;  1EI1 A;  2DEI A;  5K36 A;  4AID A;  3GME A;  4IFD C;  4JI4 I;  4OO1 A;  1N34 E;  4X64 E;  4YHH I;  5EL9 A;  4GKJ I;  4IZK A;  5JEA A;  4DV0 I;  1OYS A;  2IES A;  4LFB I;  4GKK I;  1Z5A A;  1B63 A;  1Z5C A;  1Z5B A;  1XMO E;  2V2Z A;  4JG4 A;  2PO1 A;  2JEA A;  1MG7 A;  1Z0E A;  2WW4 A;  2C38 B;  1USV A;  2UUC E;  4DR5 I;  2NN6 E;  4OZE A;  3K1J A;  4LPF A;  2PO0 A;  1MU5 A;  3T1Y I;  1FJG E;  4DV1 E;  2JE6 B;  1FWK A;  1MX0 A;  3P3G A;  3ZZ0 A;  4DV6 I;  2IOQ A;  4IFD E;  4HAC B;  2UXD E;  3LNU A;  4WUB A; 
#chains in the Genus database with same CATH homology
 3UHM A;  4LCG A;  3P3C A;  3PS1 A;  4OKG A;  4FW5 A;  1P42 A;  4LCF A;  5DRR A;  3P3E A;  4MQY A;  4IS9 A;  4U3B A;  3U1Y A;  5DRP A;  4FW3 A;  5DRO A;  2GO3 A;  4U3D A;  3NZK A;  4MDT A;  1YH8 A;  2GO4 A;  4OZE A;  2VES A;  4J3D A;  2O3Z A;  5DRQ A;  4FW7 A;  3PS3 A;  3P76 A;  4LCH A;  1XXE A;  2J65 A;  3P3G A;  4FW4 A;  1YHC A;  2IES A;  2IER A;  4FW6 A;  4ISA A;  2JT2 A;  3PS2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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