4FZ2A

Crystal structure of the fourth type of archaeal trna splicing endonuclease from candidatus micrarchaeum acidiphilum arman-2
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
386
structure length
386
Chain Sequence
TLLLNINTKAKRISVSDQSTIDILRNGYFGEYRAGKLMLEVEEGLYLVDVRKAACTDENSKPVSFNDIAGVFIKRKKLMARYFTFKDWRDRGLIIKSPGLRFGEEEHVQAKRYPSSAINLKKYSVTGIFFPDDMVTVIDDDESGKDLYENFWLGQYGTYKVSEHGNLNKLDIYETLFLIDMGVISIKNFTRAQIVNIASARRTDIMKLYDVYKDWRTKGYVVKTGFKFGTNFRIYFPGAKPIKENNEWIHSKHVLHVFPRDSKLIISEWARAIRVAHSVRKTFILAIPGKTRKKKLAIDFELYHRRGGDIEIPGKNSPRFGMLSLSENERIGGSELSAIINEAKSRKLELVIAIADSETSVTYYKVRRVDLPKSEYEYYEIDWMQP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure of the fourth type of archaeal tRNA splicing endonuclease: insights into the evolution of a novel three-unit composition and a unique loop involved in broad substrate specificity
pubmed doi rcsb
source organism Candidatus micrarchaeum acidiphilum
molecule tags Hydrolase
molecule keywords tRNA intron endonuclease
total genus 125
structure length 386
sequence length 386
chains with identical sequence B
ec nomenclature ec 3.1.27.9: Transferred entry: 4.6.1.16.
pdb deposition date 2012-07-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01974 tRNA_int_endo tRNA intron endonuclease, catalytic C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1170.20 Alpha Beta 3-Layer(aba) Sandwich MutS, DNA mismatch repair protein, domain I tRNA intron endonuclease, N-terminal domain 4fz2A01
1RLVA 3AJVA 1R0VA 4FZ2A 2ZYZB 1A79A 1R11A 3P1YA 3IEYA 2GJWA 3P1ZA 3P1ZB 2CV8A 3AJVB
chains in the Genus database with same CATH superfamily
2FWRA 2ZYZB 1WB9A 1NNEA 1A79A 3P1YA 2O8BB 3THWA 1W7AA 2O8EB 1WBBA 1OH7A 1E3MA 3THYB 2FZ4A 3THXB 3AJVA 1OH6A 2O8CA 3K0SA 1R11A 1OH5A 2GJWA 3P1ZA 2O8FA 3THYA 2CV8A 4FZ2A 2O8DB 1FW6A 3ZLJA 1OH8A 2O8CB 3P1ZB 2O8FB 1RLVA 1R0VA 3THWB 2O8EA 2O8BA 1EWQA 3IEYA 2O8DA 1NG9A 1WBDA 3THXA 2WTUA 3AJVB
chains in the Genus database with same CATH topology
1RLVA 3AJVA 1R0VA 4FZ2A 2ZYZB 1A79A 1R11A 3P1YA 3IEYA 2GJWA 3P1ZA 3P1ZB 2CV8A 3AJVB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RLV A;  3AJV A;  1R0V A;  4FZ2 A;  2ZYZ B;  1A79 A;  1R11 A;  3P1Y A;  3IEY A;  2GJW A;  3P1Z A;  3P1Z B;  2CV8 A;  3AJV B; 
#chains in the Genus database with same CATH topology
 2FWR A;  2ZYZ B;  1WB9 A;  1NNE A;  1A79 A;  3P1Y A;  2O8B B;  3THW A;  1W7A A;  2O8E B;  1WBB A;  1OH7 A;  1E3M A;  3THY B;  2FZ4 A;  3THX B;  3AJV A;  1OH6 A;  2O8C A;  3K0S A;  1R11 A;  1OH5 A;  2GJW A;  3P1Z A;  2O8F A;  3THY A;  2CV8 A;  4FZ2 A;  2O8D B;  1FW6 A;  3ZLJ A;  1OH8 A;  2O8C B;  3P1Z B;  2O8F B;  1RLV A;  1R0V A;  3THW B;  2O8E A;  2O8B A;  1EWQ A;  3IEY A;  2O8D A;  1NG9 A;  1WBD A;  3THX A;  2WTU A;  3AJV B; 
#chains in the Genus database with same CATH homology
 1RLV A;  3AJV A;  1R0V A;  4FZ2 A;  2ZYZ B;  1A79 A;  1R11 A;  3P1Y A;  3IEY A;  2GJW A;  3P1Z A;  3P1Z B;  2CV8 A;  3AJV B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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