4G3NA

Mycobacterium tuberculosis gyrase type iia topoisomerase c-terminal domain at 1.4 a resolution
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
309
structure length
302
Chain Sequence
AREDVVVTITETGYAKRTKTDLYRSQKGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxes.
pubmed doi rcsb
molecule tags Isomerase
source organism Mycobacterium tuberculosis
molecule keywords DNA gyrase subunit A
total genus 85
structure length 302
sequence length 309
ec nomenclature ec 5.99.1.3: Transferred entry: 5.6.2.3.
pdb deposition date 2012-07-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03989 DNA_gyraseA_C DNA gyrase C-terminal domain, beta-propeller
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.90 Mainly Beta 6 Propeller Neuraminidase DNA gyrase/topoisomerase IV, subunit A, C-terminal 4g3nA00
1ZI0A 1WP5A 1SUUA 3L6VA 3NO0A 3UC1A 4G3NA
chains in the Genus database with same CATH superfamily
1E8UA 1F8CA 5FZJA 2QWHA 2WOZA 2W8BA 3SOVA 1MR5A 2QE8A 4L7BA 1IVDA 1INXA 4CPLA 4GNCA 2F13A 4H52A 4FPYA 2VK7A 3WW9A 4ASCA 4K1KA 2DSOA 1N6FA 1MS1A 4MZEA 1MS4A 5H47A 1CQ1A 1IVBA 1DIMA 3V1SA 4YW3A 4FPKA 1Z50A 4N1BA 1ZI0A 1Z4ZA 1S1DA 1NNBA 4NC5A 4XJ9A 2XZKA 1V3BA 3GVJA 4IYGA 4FZHA 4FPCA 1W8NA 4XIKA 3TC9A 4C1YB 5FNUA 2VSKA 3H6JA 4QN3A 3K39A 3VNHA 4HZVA 4XE9A 5F72C 1POOA 1VCJA 2VVZA 1WP5A 2DYHA 3E5ZA 1V3DA 4IFNX 1N1SA 2HTQA 1B9VA 4I00A 3SRGA 1H6LA 2XZIA 1WCSA 3INBA 3CL2A 3HLHA 4FPJA 4KS5A 4GB1A 4CHBA 4B7MA 1SO7A 1NNCA 4FOYA 4HZYA 4XMBA 1VCUA 1EUSA 1U6DX 4XHBA 4ZY3A 1Z4VA 4MX0A 2HU0A 4XYXA 4X49A 3Q6TA 4FPOB 4IMBA 3KGGA 2QWJA 4YW1A 5GX5A 4ZGCA 1IUBA 4IQKA 1MZ6A 3K36A 4O5TA 2A75A 3TI8A 1IVEA 1NMAN 3ADEA 2W5NA 2QWCA 5EO8A 1CRUA 4JF7A 4GDIA 1W21A 3A72A 2FP8A 1B9TA 3HRPA 5HUNA 4CSDA 1XOGA 1CVMA 5HUMA 5B2DA 3KYAA 2C4LA 4XHXA 1RWLA 2IAOA 4XJRA 2VSMA 4D8SA 1IUCA 2QWEA 2JKBA 3TIBA 2IVZA 2BATA 4MJVA 5GX4A 5GX2A 2SLIA 4AHAA 4NN9A 2QWBA 1MWEA 2IATA 5FNSA 3O9JA 1IVFA 2QWKA 1NCAN 3SREA 2AEQA 2ZB6A 4KS4A 4D52B 4M4NA 3L6VA 2BZDA 4B7QA 2IARA 1Z4XA 2H2NA 2F0ZA 3LI3A 3S8VA 3TI5A 3W09A 4YZ1A 4UOUA 4H53A 3V64C 4BBWA 5GX3A 4MWJA 4CPMA 4QN4A 4MWRA 2VPJA 4HZZA 3UC1A 3DR2A 4C1YA 1W8OA 2F27A 4FPEA 2YA6A 4WA5A 4YZ2A 3HLIA 4CPNA 2F28A 4M3MA 3SOQA 1MS8A 2YA4A 3ZGCA 4GZQA 1N6DA 1NSDA 4XOGA 2HTUA 4MWXA 3GVLA 1ZGKA 2HTRA 4X4AA 1E8TA 2IAWA 4Q6KA 4FPFA 2SIMA 4XJUA 2POOA 3Q6KA 4PWZA 4HZWA 3V65B 1S0IA 1QLGA 2ISMA 5HUKA 2GVWA 4GZPA 4YW2A 2YDPA 1NCDN 2IAXA 4IFLX 4A0PA 4MWLA 3TICA 1A4GA 3A9GA 5NN9A 1L7GA 4XJAA 3U0SA 2H2UA 2IAVA 3Q6PA 4XJWA 3SLIA 1V3CA 1SNTA 4G3NA 1INVA 7NN9A 2W5OA 2F12A 2ZW9A 2IASA 1N6EA 2FPCA 2QWGA 3G4HA 1V04A 2HTVA 2Z32A 5B2CA 1NMBN 2IAPA 1F8DA 4MC7A 5M1ZA 4FOVA 2OJHA 3VNGA 1NSBA 4XJQA 3K38A 3ZGDA 1MS3A 2FP9A 4X47A 2QWDA 4KS2A 4KS3A 4MWVA 4L7CA 5F9TA 4XMIA 3B69A 4YW5A 1MS0A 1USXA 2VK5A 1L7HA 1NMCA 1Z4YA 4D52A 1CRZA 4O5SA 1E8VA 2CMLA 4HHQA 4XMAA 4GNBA 3S2KA 4GZOA 3H71A 2VW0A 4WEFA 1SLIA 4QN6A 1K32A 1NCBN 2V91A 1N1VA 4JMLA 2ZB5A 1X2RA 4M4UA 1Q7FA 3II7A 3IAXA 1NSCA 4HZXA 6NN9A 3BEQA 1MS5A 5D9CA 1V0FA 4GN8A 2C4AA 2QWAA 3OPZA 4FPLA 3O4PA 2F11A 4D52C 4CPYA 1XOEA 1NCCN 4GZTA 4UF7A 2VW2A 1INWA 3TIAA 1L7FA 2QWFA 4XILA 1MS9A 3B7EA 3TI6A 2YDTA 2GVXA 4GN9A 5EX7A 5FZNA 4IFJA 3P5BL 1INYA 3NO0A 4R40A 4AH4A 1Z4WA 3TI3A 2XCYA 3FW0A 4GZXA 4CPZA 5GX1A 4FP2A 4MWQA 1SUUA 4MWUA 3WDZA 4HHOA 1E1AA 1PJXA 4QN7A 4WA4A 4XJZA 5D9BA 2YA8A 4Q1UA 1V0ZA 2HQSA 1NNAA 1N1YA 4HW6A 4YZ5A 5D9DA 3SILA 3AMRA 4YZ4A 3G4EA 4MWWA 5FNRA 4CPOA 4D4UA 1V3EA 1X2JA 1INFA 3TI4A 1S18A 2P4OA 3PJQA 4QNPA 2FHRA 3CKZA 4GDJA 1WCQA 1IJQA 3ALXA 4FQ4A 4SLIA 4GNAA 4XJ8A 3O9KA 2ZWAA 3LI4A 1OFZA 4DGRA 1KITA 2DG1A 2DG0A 4CH9A 1F8EA 3I1CA 2B8HA 1QBIA 4B7NA 3D12A 4FVKA 4GN7A 2RKCA 3ALWA 3FVZA 4B7RA 4K3YA 4K1JA 3S8ZA 2W8BB 4L7DA 5HUGA 3H72A 2W38A 3SOBB 4MJUA 2XN4A 1MZ5A 4FP3A 2GVUA 3WN7A 4YW4A 3AMSA 1B9SA 3H73A 2W20A 5FWWA 1DILA 1W0PA 3NN9A 4GJTA 4FJ6A 3S94A 2HT5A 5FNQA 2ZZKA 2GHSA 3SALA 4K1IA 4YY8A 1INGA 2AEPA 1W20A 2FPBA 1EUTA 3K37A 4B7JA 4K1HA 1V2IA 2YA5A 4NCSA 2AGSA 4HIZA 4FOWA 2VWDA 2HU4A 4WA3A 3LI5A 4X6KA 3T1EA 2G8SA 1W0OA 5JYYA 2GVVA 1BJIA 2AH2A 3CYEA 2YA7A 4KS1A 4FPGA 1V0EA 1A4QA 5CGJA 4FOQA 4AGIA 4MZAA 1EURA 2VW1A 1N7DA 1NN2A 3DASA 4ZLRA 3WWAA 1NPEA 1F8BA 2HT7A 2QWIA 2SILA 4QN5A 1SLLA 1N1TA 4WEGA 1IVGA 2BF6A 1A14N 4GZWA 2X9MA 4DG6A 3A71A 5GTQA 4IN4A 2F24A 1INHA 2HTWA 3BYCA 2F10A 2F29A 2IAQA 1EUUA 4MWYA 3SANA 1C9UA 2IAUA 2VK6A 2BERA 3CL0A 5HX0A 1USRA 4M4VA 2FLUX 1RWIA 4GZSA 3D11A 2F25A 3A9HA 4XIOA 1W1XA 2F26A 1IVCA 4GEZA 5EO7A 5FNTA 2XZJA 4AGTA 4FPHA 3JU4A 4YZ3A 2HT8A 1C5KA 2VAQA 3GVKA 1S0JA 3NSSA 3K3AA 4J9TA 2HTYA
chains in the Genus database with same CATH topology
1ZI0A 1WP5A 1SUUA 3L6VA 3NO0A 3UC1A 4G3NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZI0 A;  1WP5 A;  1SUU A;  3L6V A;  3NO0 A;  3UC1 A;  4G3N A; 
#chains in the Genus database with same CATH topology
 1E8U A;  1F8C A;  5FZJ A;  2QWH A;  2WOZ A;  2W8B A;  3SOV A;  1MR5 A;  2QE8 A;  4L7B A;  1IVD A;  1INX A;  4CPL A;  4GNC A;  2F13 A;  4H52 A;  4FPY A;  2VK7 A;  3WW9 A;  4ASC A;  4K1K A;  2DSO A;  1N6F A;  1MS1 A;  4MZE A;  1MS4 A;  5H47 A;  1CQ1 A;  1IVB A;  1DIM A;  3V1S A;  4YW3 A;  4FPK A;  1Z50 A;  4N1B A;  1ZI0 A;  1Z4Z A;  1S1D A;  1NNB A;  4NC5 A;  4XJ9 A;  2XZK A;  1V3B A;  3GVJ A;  4IYG A;  4FZH A;  4FPC A;  1W8N A;  4XIK A;  3TC9 A;  4C1Y B;  5FNU A;  2VSK A;  3H6J A;  4QN3 A;  3K39 A;  3VNH A;  4HZV A;  4XE9 A;  5F72 C;  1POO A;  1VCJ A;  2VVZ A;  1WP5 A;  2DYH A;  3E5Z A;  1V3D A;  4IFN X;  1N1S A;  2HTQ A;  1B9V A;  4I00 A;  3SRG A;  1H6L A;  2XZI A;  1WCS A;  3INB A;  3CL2 A;  3HLH A;  4FPJ A;  4KS5 A;  4GB1 A;  4CHB A;  4B7M A;  1SO7 A;  1NNC A;  4FOY A;  4HZY A;  4XMB A;  1VCU A;  1EUS A;  1U6D X;  4XHB A;  4ZY3 A;  1Z4V A;  4MX0 A;  2HU0 A;  4XYX A;  4X49 A;  3Q6T A;  4FPO B;  4IMB A;  3KGG A;  2QWJ A;  4YW1 A;  5GX5 A;  4ZGC A;  1IUB A;  4IQK A;  1MZ6 A;  3K36 A;  4O5T A;  2A75 A;  3TI8 A;  1IVE A;  1NMA N;  3ADE A;  2W5N A;  2QWC A;  5EO8 A;  1CRU A;  4JF7 A;  4GDI A;  1W21 A;  3A72 A;  2FP8 A;  1B9T A;  3HRP A;  5HUN A;  4CSD A;  1XOG A;  1CVM A;  5HUM A;  5B2D A;  3KYA A;  2C4L A;  4XHX A;  1RWL A;  2IAO A;  4XJR A;  2VSM A;  4D8S A;  1IUC A;  2QWE A;  2JKB A;  3TIB A;  2IVZ A;  2BAT A;  4MJV A;  5GX4 A;  5GX2 A;  2SLI A;  4AHA A;  4NN9 A;  2QWB A;  1MWE A;  2IAT A;  5FNS A;  3O9J A;  1IVF A;  2QWK A;  1NCA N;  3SRE A;  2AEQ A;  2ZB6 A;  4KS4 A;  4D52 B;  4M4N A;  3L6V A;  2BZD A;  4B7Q A;  2IAR A;  1Z4X A;  2H2N A;  2F0Z A;  3LI3 A;  3S8V A;  3TI5 A;  3W09 A;  4YZ1 A;  4UOU A;  4H53 A;  3V64 C;  4BBW A;  5GX3 A;  4MWJ A;  4CPM A;  4QN4 A;  4MWR A;  2VPJ A;  4HZZ A;  3UC1 A;  3DR2 A;  4C1Y A;  1W8O A;  2F27 A;  4FPE A;  2YA6 A;  4WA5 A;  4YZ2 A;  3HLI A;  4CPN A;  2F28 A;  4M3M A;  3SOQ A;  1MS8 A;  2YA4 A;  3ZGC A;  4GZQ A;  1N6D A;  1NSD A;  4XOG A;  2HTU A;  4MWX A;  3GVL A;  1ZGK A;  2HTR A;  4X4A A;  1E8T A;  2IAW A;  4Q6K A;  4FPF A;  2SIM A;  4XJU A;  2POO A;  3Q6K A;  4PWZ A;  4HZW A;  3V65 B;  1S0I A;  1QLG A;  2ISM A;  5HUK A;  2GVW A;  4GZP A;  4YW2 A;  2YDP A;  1NCD N;  2IAX A;  4IFL X;  4A0P A;  4MWL A;  3TIC A;  1A4G A;  3A9G A;  5NN9 A;  1L7G A;  4XJA A;  3U0S A;  2H2U A;  2IAV A;  3Q6P A;  4XJW A;  3SLI A;  1V3C A;  1SNT A;  4G3N A;  1INV A;  7NN9 A;  2W5O A;  2F12 A;  2ZW9 A;  2IAS A;  1N6E A;  2FPC A;  2QWG A;  3G4H A;  1V04 A;  2HTV A;  2Z32 A;  5B2C A;  1NMB N;  2IAP A;  1F8D A;  4MC7 A;  5M1Z A;  4FOV A;  2OJH A;  3VNG A;  1NSB A;  4XJQ A;  3K38 A;  3ZGD A;  1MS3 A;  2FP9 A;  4X47 A;  2QWD A;  4KS2 A;  4KS3 A;  4MWV A;  4L7C A;  5F9T A;  4XMI A;  3B69 A;  4YW5 A;  1MS0 A;  1USX A;  2VK5 A;  1L7H A;  1NMC A;  1Z4Y A;  4D52 A;  1CRZ A;  4O5S A;  1E8V A;  2CML A;  4HHQ A;  4XMA A;  4GNB A;  3S2K A;  4GZO A;  3H71 A;  2VW0 A;  4WEF A;  1SLI A;  4QN6 A;  1K32 A;  1NCB N;  2V91 A;  1N1V A;  4JML A;  2ZB5 A;  1X2R A;  4M4U A;  1Q7F A;  3II7 A;  3IAX A;  1NSC A;  4HZX A;  6NN9 A;  3BEQ A;  1MS5 A;  5D9C A;  1V0F A;  4GN8 A;  2C4A A;  2QWA A;  3OPZ A;  4FPL A;  3O4P A;  2F11 A;  4D52 C;  4CPY A;  1XOE A;  1NCC N;  4GZT A;  4UF7 A;  2VW2 A;  1INW A;  3TIA A;  1L7F A;  2QWF A;  4XIL A;  1MS9 A;  3B7E A;  3TI6 A;  2YDT A;  2GVX A;  4GN9 A;  5EX7 A;  5FZN A;  4IFJ A;  3P5B L;  1INY A;  3NO0 A;  4R40 A;  4AH4 A;  1Z4W A;  3TI3 A;  2XCY A;  3FW0 A;  4GZX A;  4CPZ A;  5GX1 A;  4FP2 A;  4MWQ A;  1SUU A;  4MWU A;  3WDZ A;  4HHO A;  1E1A A;  1PJX A;  4QN7 A;  4WA4 A;  4XJZ A;  5D9B A;  2YA8 A;  4Q1U A;  1V0Z A;  2HQS A;  1NNA A;  1N1Y A;  4HW6 A;  4YZ5 A;  5D9D A;  3SIL A;  3AMR A;  4YZ4 A;  3G4E A;  4MWW A;  5FNR A;  4CPO A;  4D4U A;  1V3E A;  1X2J A;  1INF A;  3TI4 A;  1S18 A;  2P4O A;  3PJQ A;  4QNP A;  2FHR A;  3CKZ A;  4GDJ A;  1WCQ A;  1IJQ A;  3ALX A;  4FQ4 A;  4SLI A;  4GNA A;  4XJ8 A;  3O9K A;  2ZWA A;  3LI4 A;  1OFZ A;  4DGR A;  1KIT A;  2DG1 A;  2DG0 A;  4CH9 A;  1F8E A;  3I1C A;  2B8H A;  1QBI A;  4B7N A;  3D12 A;  4FVK A;  4GN7 A;  2RKC A;  3ALW A;  3FVZ A;  4B7R A;  4K3Y A;  4K1J A;  3S8Z A;  2W8B B;  4L7D A;  5HUG A;  3H72 A;  2W38 A;  3SOB B;  4MJU A;  2XN4 A;  1MZ5 A;  4FP3 A;  2GVU A;  3WN7 A;  4YW4 A;  3AMS A;  1B9S A;  3H73 A;  2W20 A;  5FWW A;  1DIL A;  1W0P A;  3NN9 A;  4GJT A;  4FJ6 A;  3S94 A;  2HT5 A;  5FNQ A;  2ZZK A;  2GHS A;  3SAL A;  4K1I A;  4YY8 A;  1ING A;  2AEP A;  1W20 A;  2FPB A;  1EUT A;  3K37 A;  4B7J A;  4K1H A;  1V2I A;  2YA5 A;  4NCS A;  2AGS A;  4HIZ A;  4FOW A;  2VWD A;  2HU4 A;  4WA3 A;  3LI5 A;  4X6K A;  3T1E A;  2G8S A;  1W0O A;  5JYY A;  2GVV A;  1BJI A;  2AH2 A;  3CYE A;  2YA7 A;  4KS1 A;  4FPG A;  1V0E A;  1A4Q A;  5CGJ A;  4FOQ A;  4AGI A;  4MZA A;  1EUR A;  2VW1 A;  1N7D A;  1NN2 A;  3DAS A;  4ZLR A;  3WWA A;  1NPE A;  1F8B A;  2HT7 A;  2QWI A;  2SIL A;  4QN5 A;  1SLL A;  1N1T A;  4WEG A;  1IVG A;  2BF6 A;  1A14 N;  4GZW A;  2X9M A;  4DG6 A;  3A71 A;  5GTQ A;  4IN4 A;  2F24 A;  1INH A;  2HTW A;  3BYC A;  2F10 A;  2F29 A;  2IAQ A;  1EUU A;  4MWY A;  3SAN A;  1C9U A;  2IAU A;  2VK6 A;  2BER A;  3CL0 A;  5HX0 A;  1USR A;  4M4V A;  2FLU X;  1RWI A;  4GZS A;  3D11 A;  2F25 A;  3A9H A;  4XIO A;  1W1X A;  2F26 A;  1IVC A;  4GEZ A;  5EO7 A;  5FNT A;  2XZJ A;  4AGT A;  4FPH A;  3JU4 A;  4YZ3 A;  2HT8 A;  1C5K A;  2VAQ A;  3GVK A;  1S0J A;  3NSS A;  3K3A A;  4J9T A;  2HTY A; 
#chains in the Genus database with same CATH homology
 1ZI0 A;  1WP5 A;  1SUU A;  3L6V A;  3NO0 A;  3UC1 A;  4G3N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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