4G3NA

Mycobacterium tuberculosis gyrase type iia topoisomerase c-terminal domain at 1.4 a resolution
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
309
structure length
302
Chain Sequence
AREDVVVTITETGYAKRTKTDLYRSQKGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxes.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Isomerase
molecule keywords DNA gyrase subunit A
total genus 85
structure length 302
sequence length 309
ec nomenclature ec 5.99.1.3: Transferred entry: 5.6.2.3.
pdb deposition date 2012-07-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03989 DNA_gyraseA_C DNA gyrase C-terminal domain, beta-propeller
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.90 Mainly Beta 6 Propeller Neuraminidase DNA gyrase/topoisomerase IV, subunit A, C-terminal 4g3nA00
4G3NA 1ZI0A 1SUUA 1WP5A 3NO0A 3UC1A 3L6VA
chains in the Genus database with same CATH superfamily
4DGRA 2POOA 2Z32A 2FP9A 4NN9A 1V3BA 5NN9A 2XZKA 2IAOA 1INYA 4A0PA 1NPEA 5EX7A 2H2NA 4UF7A 4XMAA 4UOUA 1N1TA 1Z50A 7NN9A 1INWA 4MX0A 4HZVA 1SLLA 4GZXA 4D52A 4YZ1A 3CL0A 1N7DA 5FWWA 4QN4A 3L6VA 1NN2A 1INXA 3Q6KA 3FW0A 4QN3A 1W0PA 2AEQA 1USRA 4D52B 4X4AA 4I00A 1W21A 5GTQA 2IATA 1IVGA 1W0OA 4QN5A 1B9SA 2BATA 4YW1A 2GVVA 4C1YA 1NSDA 2W5OA 2BF6A 3K39A 2FPCA 4HHOA 1V3DA 1IUCA 4MJUA 4BBWA 4B7QA 1CRZA 1A4QA 5M1ZA 1MS0A 1NCBN 4DG6A 4XJUA 1CVMA 1N6FA 2W8BB 4FPCA 3V1SA 2VW2A 4YW5A 2XCYA 4XIOA 1U6DX 2IAXA 2A75A 2HT7A 2H2UA 3O9JA 3P5BL 1ZI0A 4WEFA 2DG1A 2HTYA 1OFZA 2C4LA 5HUMA 2HTWA 3W09A 4SLIA 4FPJA 1EUUA 2C4AA 2QWFA 3CL2A 1XOEA 1IUBA 2FHRA 4M4UA 4K1IA 1QLGA 4JF7A 1BJIA 5FNTA 3NSSA 1IVDA 2OJHA 1NNAA 2VVZA 2F13A 4XJWA 2GVUA 1V3EA 3Q6PA 4YZ2A 4XIKA 5EO7A 1Z4VA 1N1SA 1Q7FA 4IN4A 4FOQA 3HRPA 4K1JA 1MZ5A 1VCUA 3TC9A 3GVKA 1V0FA 3V65B 1F8DA 4H53A 1IVCA 4YY8A 1S0JA 2QWIA 1L7GA 4YW4A 1N1YA 5D9BA 1Z4XA 2V91A 2F28A 3TIBA 3V64C 4AHAA 3ADEA 5GX5A 4ASCA 1NNCA 1VCJA 1DIMA 1WP5A 2VWDA 4CPLA 3O4PA 2VK6A 2X9MA 1NNBA 1CQ1A 3K37A 4HZYA 3NO0A 3G4HA 4M4NA 4QN7A 3OPZA 1B9VA 1E8VA 4L7DA 2ZB5A 4MWWA 4X47A 5D9DA 3H73A 4MWVA 4GN9A 1EUTA 4K1KA 1PJXA 4GEZA 1MS5A 4IYGA 3SOVA 2IASA 1E8TA 3SANA 4D52C 1WCQA 1NCCN 1RWIA 2VK5A 3AMSA 3II7A 2W8BA 4O5TA 4XYXA 4MWXA 5FNQA 4KS5A 1E8UA 4WA4A 5CGJA 3TI5A 1W1XA 4QN6A 4XILA 4C1YB 3GVJA 2F24A 1NSBA 4XE9A 1A4GA 1W20A 1E1AA 2BZDA 1V0EA 1ZGKA 4Q6KA 2IARA 1Z4ZA 1NSCA 4FOVA 1W8NA 2F27A 4IFNX 3SREA 2HT5A 2QE8A 2FP8A 3ALWA 4L7CA 2AGSA 1F8BA 4XJ9A 2DSOA 2ISMA 3CYEA 4WA5A 1S0IA 1POOA 2SILA 2SLIA 4MZEA 2FLUX 2ZWAA 3GVLA 4NCSA 4KS1A 2HQSA 4FPEA 2W5NA 4XJAA 2F25A 2ZB6A 1N6DA 4JMLA 4FPOB 1EURA 4Q1UA 2F12A 1V04A 3SLIA 1H6LA 4YW3A 2XN4A 4KS2A 3SILA 3DASA 3T1EA 2AEPA 4FP2A 3KGGA 3CKZA 2YA5A 2QWGA 4MZAA 5HUKA 2F10A 4PWZA 1S18A 2GVWA 2XZIA 5JYYA 2VK7A 2YDPA 4FPKA 2AH2A 4YW2A 1IVEA 1N6EA 2F26A 1MS4A 4MWLA 5GX1A 4MWUA 3WWAA 2F0ZA 3NN9A 4CHBA 2P4OA 1NMCA 1SLIA 5D9CA 3WN7A 3UC1A 4FOYA 4X6KA 4YZ3A 3S8VA 4GNAA 4CPMA 2VAQA 1KITA 1NCDN 2QWCA 3TICA 4GZPA 5B2DA 2HTUA 2YA4A 2W20A 2RKCA 4CH9A 4YZ4A 5B2CA 4GZWA 4FOWA 4FPYA 5GX3A 4GN8A 4FQ4A 4IFJA 1X2JA 2GVXA 3TI3A 3INBA 4G3NA 4WA3A 4FPFA 3AMRA 2DG0A 4GN7A 3LI4A 4FVKA 1MZ6A 4L7BA 4HZXA 2YA7A 1MS3A 3BEQA 4MWQA 2QWJA 1C5KA 3B7EA 4GNBA 4IFLX 3H72A 3KYAA 1IVFA 3I1CA 1L7FA 2ZZKA 1MS9A 4K1HA 1IVBA 2DYHA 3B69A 4IMBA 4WEGA 4O5SA 5GX2A 1B9TA 4FPGA 3A9HA 2HT8A 4GNCA 3A71A 4FPHA 2VW1A 2IAPA 3WW9A 5HX0A 4GZSA 2HTQA 1INHA 1C9UA 2QWEA 4H52A 1S1DA 4XHBA 5FNRA 4MC7A 2YA6A 4CSDA 2IAQA 3K36A 4GZOA 4X49A 2QWBA 4XHXA 4MJVA 4XJRA 5HUNA 1Z4YA 2VSKA 3JU4A 5H47A 1WCSA 4K3YA 3SOBB 3VNGA 4N1BA 3U0SA 3BYCA 3H71A 4ZLRA 2HU0A 2QWHA 4XOGA 1CRUA 4XJ8A 4MWYA 5FNSA 1EUSA 6NN9A 1INGA 2SIMA 4FP3A 1INVA 3K3AA 1DILA 2B8HA 2VPJA 4XMIA 4B7NA 4CPYA 2VSMA 4B7JA 2W38A 4FJ6A 2G8SA 4AGIA 3D11A 4XJQA 3ZGCA 1SO7A 1MR5A 4KS4A 3TI4A 4M3MA 2CMLA 3HLHA 1F8EA 4HZWA 1NMBN 2IAVA 1IJQA 2HTVA 1W8OA 5EO8A 2IVZA 3A9GA 2GHSA 4NC5A 4HIZA 1K32A 5GX4A 4QNPA 3HLIA 4CPOA 3IAXA 4AGTA 4ZGCA 3ZGDA 2YDTA 1MS8A 4CPZA 4GZTA 4GDIA 4XJZA 2HU4A 3WDZA 3A72A 1QBIA 1NCAN 3K38A 2F29A 2IAUA 1V2IA 4KS3A 2F11A 4XMBA 4HHQA 4J9TA 1L7HA 4YZ5A 1SUUA 5FZNA 3TIAA 1XOGA 3DR2A 2ZW9A 1MWEA 4HZZA 4AH4A 3H6JA 3FVZA 1USXA 4FPLA 1X2RA 3G4EA 4R40A 5FNUA 1SNTA 2IAWA 3ALXA 3Q6TA 2VW0A 3S2KA 4M4VA 3S94A 4GB1A 4B7RA 4MWJA 1N1VA 2QWKA 2YA8A 5F72C 1A14N 1INFA 2WOZA 5F9TA 4MWRA 3TI6A 3LI5A 2XZJA 1NMAN 3SALA 4ZY3A 1F8CA 4B7MA 2QWAA 1RWLA 3D12A 1V0ZA 2BERA 3E5ZA 4GJTA 2HTRA 5FZJA 3LI3A 1MS1A 4IQKA 3VNHA 4GDJA 4FZHA 5HUGA 1Z4WA 3PJQA 3SRGA 3S8ZA 4CPNA 4D4UA 2QWDA 3TI8A 4D8SA 2FPBA 3SOQA 3O9KA 4GZQA 1V3CA 2JKBA 4HW6A
chains in the Genus database with same CATH topology
4G3NA 1ZI0A 1SUUA 1WP5A 3NO0A 3UC1A 3L6VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4G3N A;  1ZI0 A;  1SUU A;  1WP5 A;  3NO0 A;  3UC1 A;  3L6V A; 
#chains in the Genus database with same CATH topology
 4DGR A;  2POO A;  2Z32 A;  2FP9 A;  4NN9 A;  1V3B A;  5NN9 A;  2XZK A;  2IAO A;  1INY A;  4A0P A;  1NPE A;  5EX7 A;  2H2N A;  4UF7 A;  4XMA A;  4UOU A;  1N1T A;  1Z50 A;  7NN9 A;  1INW A;  4MX0 A;  4HZV A;  1SLL A;  4GZX A;  4D52 A;  4YZ1 A;  3CL0 A;  1N7D A;  5FWW A;  4QN4 A;  3L6V A;  1NN2 A;  1INX A;  3Q6K A;  3FW0 A;  4QN3 A;  1W0P A;  2AEQ A;  1USR A;  4D52 B;  4X4A A;  4I00 A;  1W21 A;  5GTQ A;  2IAT A;  1IVG A;  1W0O A;  4QN5 A;  1B9S A;  2BAT A;  4YW1 A;  2GVV A;  4C1Y A;  1NSD A;  2W5O A;  2BF6 A;  3K39 A;  2FPC A;  4HHO A;  1V3D A;  1IUC A;  4MJU A;  4BBW A;  4B7Q A;  1CRZ A;  1A4Q A;  5M1Z A;  1MS0 A;  1NCB N;  4DG6 A;  4XJU A;  1CVM A;  1N6F A;  2W8B B;  4FPC A;  3V1S A;  2VW2 A;  4YW5 A;  2XCY A;  4XIO A;  1U6D X;  2IAX A;  2A75 A;  2HT7 A;  2H2U A;  3O9J A;  3P5B L;  1ZI0 A;  4WEF A;  2DG1 A;  2HTY A;  1OFZ A;  2C4L A;  5HUM A;  2HTW A;  3W09 A;  4SLI A;  4FPJ A;  1EUU A;  2C4A A;  2QWF A;  3CL2 A;  1XOE A;  1IUB A;  2FHR A;  4M4U A;  4K1I A;  1QLG A;  4JF7 A;  1BJI A;  5FNT A;  3NSS A;  1IVD A;  2OJH A;  1NNA A;  2VVZ A;  2F13 A;  4XJW A;  2GVU A;  1V3E A;  3Q6P A;  4YZ2 A;  4XIK A;  5EO7 A;  1Z4V A;  1N1S A;  1Q7F A;  4IN4 A;  4FOQ A;  3HRP A;  4K1J A;  1MZ5 A;  1VCU A;  3TC9 A;  3GVK A;  1V0F A;  3V65 B;  1F8D A;  4H53 A;  1IVC A;  4YY8 A;  1S0J A;  2QWI A;  1L7G A;  4YW4 A;  1N1Y A;  5D9B A;  1Z4X A;  2V91 A;  2F28 A;  3TIB A;  3V64 C;  4AHA A;  3ADE A;  5GX5 A;  4ASC A;  1NNC A;  1VCJ A;  1DIM A;  1WP5 A;  2VWD A;  4CPL A;  3O4P A;  2VK6 A;  2X9M A;  1NNB A;  1CQ1 A;  3K37 A;  4HZY A;  3NO0 A;  3G4H A;  4M4N A;  4QN7 A;  3OPZ A;  1B9V A;  1E8V A;  4L7D A;  2ZB5 A;  4MWW A;  4X47 A;  5D9D A;  3H73 A;  4MWV A;  4GN9 A;  1EUT A;  4K1K A;  1PJX A;  4GEZ A;  1MS5 A;  4IYG A;  3SOV A;  2IAS A;  1E8T A;  3SAN A;  4D52 C;  1WCQ A;  1NCC N;  1RWI A;  2VK5 A;  3AMS A;  3II7 A;  2W8B A;  4O5T A;  4XYX A;  4MWX A;  5FNQ A;  4KS5 A;  1E8U A;  4WA4 A;  5CGJ A;  3TI5 A;  1W1X A;  4QN6 A;  4XIL A;  4C1Y B;  3GVJ A;  2F24 A;  1NSB A;  4XE9 A;  1A4G A;  1W20 A;  1E1A A;  2BZD A;  1V0E A;  1ZGK A;  4Q6K A;  2IAR A;  1Z4Z A;  1NSC A;  4FOV A;  1W8N A;  2F27 A;  4IFN X;  3SRE A;  2HT5 A;  2QE8 A;  2FP8 A;  3ALW A;  4L7C A;  2AGS A;  1F8B A;  4XJ9 A;  2DSO A;  2ISM A;  3CYE A;  4WA5 A;  1S0I A;  1POO A;  2SIL A;  2SLI A;  4MZE A;  2FLU X;  2ZWA A;  3GVL A;  4NCS A;  4KS1 A;  2HQS A;  4FPE A;  2W5N A;  4XJA A;  2F25 A;  2ZB6 A;  1N6D A;  4JML A;  4FPO B;  1EUR A;  4Q1U A;  2F12 A;  1V04 A;  3SLI A;  1H6L A;  4YW3 A;  2XN4 A;  4KS2 A;  3SIL A;  3DAS A;  3T1E A;  2AEP A;  4FP2 A;  3KGG A;  3CKZ A;  2YA5 A;  2QWG A;  4MZA A;  5HUK A;  2F10 A;  4PWZ A;  1S18 A;  2GVW A;  2XZI A;  5JYY A;  2VK7 A;  2YDP A;  4FPK A;  2AH2 A;  4YW2 A;  1IVE A;  1N6E A;  2F26 A;  1MS4 A;  4MWL A;  5GX1 A;  4MWU A;  3WWA A;  2F0Z A;  3NN9 A;  4CHB A;  2P4O A;  1NMC A;  1SLI A;  5D9C A;  3WN7 A;  3UC1 A;  4FOY A;  4X6K A;  4YZ3 A;  3S8V A;  4GNA A;  4CPM A;  2VAQ A;  1KIT A;  1NCD N;  2QWC A;  3TIC A;  4GZP A;  5B2D A;  2HTU A;  2YA4 A;  2W20 A;  2RKC A;  4CH9 A;  4YZ4 A;  5B2C A;  4GZW A;  4FOW A;  4FPY A;  5GX3 A;  4GN8 A;  4FQ4 A;  4IFJ A;  1X2J A;  2GVX A;  3TI3 A;  3INB A;  4G3N A;  4WA3 A;  4FPF A;  3AMR A;  2DG0 A;  4GN7 A;  3LI4 A;  4FVK A;  1MZ6 A;  4L7B A;  4HZX A;  2YA7 A;  1MS3 A;  3BEQ A;  4MWQ A;  2QWJ A;  1C5K A;  3B7E A;  4GNB A;  4IFL X;  3H72 A;  3KYA A;  1IVF A;  3I1C A;  1L7F A;  2ZZK A;  1MS9 A;  4K1H A;  1IVB A;  2DYH A;  3B69 A;  4IMB A;  4WEG A;  4O5S A;  5GX2 A;  1B9T A;  4FPG A;  3A9H A;  2HT8 A;  4GNC A;  3A71 A;  4FPH A;  2VW1 A;  2IAP A;  3WW9 A;  5HX0 A;  4GZS A;  2HTQ A;  1INH A;  1C9U A;  2QWE A;  4H52 A;  1S1D A;  4XHB A;  5FNR A;  4MC7 A;  2YA6 A;  4CSD A;  2IAQ A;  3K36 A;  4GZO A;  4X49 A;  2QWB A;  4XHX A;  4MJV A;  4XJR A;  5HUN A;  1Z4Y A;  2VSK A;  3JU4 A;  5H47 A;  1WCS A;  4K3Y A;  3SOB B;  3VNG A;  4N1B A;  3U0S A;  3BYC A;  3H71 A;  4ZLR A;  2HU0 A;  2QWH A;  4XOG A;  1CRU A;  4XJ8 A;  4MWY A;  5FNS A;  1EUS A;  6NN9 A;  1ING A;  2SIM A;  4FP3 A;  1INV A;  3K3A A;  1DIL A;  2B8H A;  2VPJ A;  4XMI A;  4B7N A;  4CPY A;  2VSM A;  4B7J A;  2W38 A;  4FJ6 A;  2G8S A;  4AGI A;  3D11 A;  4XJQ A;  3ZGC A;  1SO7 A;  1MR5 A;  4KS4 A;  3TI4 A;  4M3M A;  2CML A;  3HLH A;  1F8E A;  4HZW A;  1NMB N;  2IAV A;  1IJQ A;  2HTV A;  1W8O A;  5EO8 A;  2IVZ A;  3A9G A;  2GHS A;  4NC5 A;  4HIZ A;  1K32 A;  5GX4 A;  4QNP A;  3HLI A;  4CPO A;  3IAX A;  4AGT A;  4ZGC A;  3ZGD A;  2YDT A;  1MS8 A;  4CPZ A;  4GZT A;  4GDI A;  4XJZ A;  2HU4 A;  3WDZ A;  3A72 A;  1QBI A;  1NCA N;  3K38 A;  2F29 A;  2IAU A;  1V2I A;  4KS3 A;  2F11 A;  4XMB A;  4HHQ A;  4J9T A;  1L7H A;  4YZ5 A;  1SUU A;  5FZN A;  3TIA A;  1XOG A;  3DR2 A;  2ZW9 A;  1MWE A;  4HZZ A;  4AH4 A;  3H6J A;  3FVZ A;  1USX A;  4FPL A;  1X2R A;  3G4E A;  4R40 A;  5FNU A;  1SNT A;  2IAW A;  3ALX A;  3Q6T A;  2VW0 A;  3S2K A;  4M4V A;  3S94 A;  4GB1 A;  4B7R A;  4MWJ A;  1N1V A;  2QWK A;  2YA8 A;  5F72 C;  1A14 N;  1INF A;  2WOZ A;  5F9T A;  4MWR A;  3TI6 A;  3LI5 A;  2XZJ A;  1NMA N;  3SAL A;  4ZY3 A;  1F8C A;  4B7M A;  2QWA A;  1RWL A;  3D12 A;  1V0Z A;  2BER A;  3E5Z A;  4GJT A;  2HTR A;  5FZJ A;  3LI3 A;  1MS1 A;  4IQK A;  3VNH A;  4GDJ A;  4FZH A;  5HUG A;  1Z4W A;  3PJQ A;  3SRG A;  3S8Z A;  4CPN A;  4D4U A;  2QWD A;  3TI8 A;  4D8S A;  2FPB A;  3SOQ A;  3O9K A;  4GZQ A;  1V3C A;  2JKB A;  4HW6 A; 
#chains in the Genus database with same CATH homology
 4G3N A;  1ZI0 A;  1SUU A;  1WP5 A;  3NO0 A;  3UC1 A;  3L6V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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