4G7LA

Crystal structure of rat heme oxygenase-1 in complex with heme and o2
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
213
structure length
213
Chain Sequence
QDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Heme oxygenase 1
publication title Discrimination between CO and O2 in Heme Oxygenase: Comparison of Static Structures and Dynamic Conformation Changes following CO Photolysis
pubmed doi rcsb
source organism Rattus norvegicus
total genus 93
structure length 213
sequence length 213
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2012-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 4g7lA00
5BTQA 3HOKA 1IW1A 3MVUA 4MECA 4G7TA 1OYKA 4G8PA 4G8UA 3BJDA 1Z72A 1XJZA 2A2MA 2A6BA 3I9TA 1UDDA 1WOVA 2Q32A 4WWZA 1WOXA 3B5OA 1OTWA 1YAFA 1IX4A 4WWJA 2RGZA 3I9UA 4WMHA 4GOHA 1V8XA 3IBXA 2DY5A 3HNHA 2GM7A 3CZYA 1XK0A 2Q4XA 1IRMA 4NY7A 1IW0A 1WNXA 2GM8A 1OZEA 1P3VA 2RD3A 1OYLA 1TO9B 1S8CA 4GPFA 1XK1A 1WZFA 1WOWA 2A2OA 1DVEA 1WZGA 1IX3A 1WNWA 4WD4A 4G7LA 3MOOA 4WX0A 1RCWA 1RTWA 4LQXA 1TWNA 3K4FA 2QCXA 1NI6A 1J77A 3I8RA 4RAJA 1S13A 1DVGA 2QZCA 4FN6A 3B5PA 3HLXA 1TWRA 3TGMA 3HMLA 1N45A 1VGIA 2E7EA 1OTVA 1J2CA 4G7UA 3DDEA 4GPHA 1J02A 1TYHA 1YAKA 1ULXA 1XK2A 1WNVA 4G7PA 3RM5A 1WWMA 3OQLA 1N3UA 1OZWA 1TO9A 2ZVUA 1IVJA 1OZRA 2F2GA 4G99A 4G8WA 1SK7A 1XK3A 1UBBA 3NO6A 1T5PA 1OZLA 1WZDA 4G98A 1P3TA 2QPPA 2Z68A 1WE1A 1P3UA 4GPCA
chains in the Genus database with same CATH superfamily
5BTQA 3HOKA 1IW1A 3MVUA 4MECA 4G7TA 1OYKA 4G8PA 4G8UA 3BJDA 1Z72A 1XJZA 2A2MA 2A6BA 3I9TA 1UDDA 1WOVA 2Q32A 4WWZA 1WOXA 3B5OA 1OTWA 1YAFA 1IX4A 4WWJA 2RGZA 3I9UA 4WMHA 4GOHA 1V8XA 3IBXA 2DY5A 3HNHA 2GM7A 3CZYA 1XK0A 2Q4XA 1IRMA 4NY7A 1IW0A 1WNXA 2GM8A 1OZEA 1P3VA 2RD3A 1OYLA 1TO9B 1S8CA 4GPFA 1XK1A 1WZFA 1WOWA 2A2OA 1DVEA 1WZGA 1IX3A 1WNWA 4WD4A 4G7LA 3MOOA 4WX0A 1RCWA 1RTWA 4LQXA 1TWNA 3K4FA 2QCXA 1NI6A 1J77A 3I8RA 4RAJA 1S13A 1DVGA 2QZCA 4FN6A 3B5PA 3HLXA 1TWRA 3TGMA 3HMLA 1N45A 1VGIA 2E7EA 1OTVA 2LCUA 1J2CA 4G7UA 3DDEA 4GPHA 1J02A 1TYHA 1YAKA 1ULXA 1XK2A 1WNVA 4G7PA 3RM5A 1WWMA 3OQLA 1N3UA 1OZWA 1TO9A 2ZVUA 1IVJA 1OZRA 2F2GA 4G99A 4G8WA 1SK7A 1XK3A 1UBBA 3NO6A 1T5PA 1OZLA 1WZDA 4G98A 1P3TA 2QPPA 2Z68A 1WE1A 1P3UA 4GPCA
chains in the Genus database with same CATH topology
5BTQA 3HOKA 1IW1A 3MVUA 4MECA 4G7TA 1OYKA 4G8PA 4G8UA 3BJDA 1Z72A 1XJZA 2A2MA 2A6BA 3I9TA 1UDDA 1WOVA 2Q32A 4WWZA 1WOXA 3B5OA 1OTWA 1YAFA 1IX4A 4WWJA 2RGZA 3I9UA 4WMHA 4GOHA 1V8XA 3IBXA 2DY5A 3HNHA 2GM7A 3CZYA 1XK0A 2Q4XA 1IRMA 4NY7A 1IW0A 1WNXA 2GM8A 1OZEA 1P3VA 2RD3A 1OYLA 1TO9B 1S8CA 4GPFA 1XK1A 1WZFA 1WOWA 2A2OA 1DVEA 1WZGA 1IX3A 1WNWA 4WD4A 4G7LA 3MOOA 4WX0A 1RCWA 1RTWA 4LQXA 1TWNA 3K4FA 2QCXA 1NI6A 1J77A 3I8RA 4RAJA 1S13A 1DVGA 2QZCA 4FN6A 3B5PA 3HLXA 1TWRA 3TGMA 3HMLA 1N45A 1VGIA 2E7EA 1OTVA 1J2CA 4G7UA 3DDEA 4GPHA 1J02A 1TYHA 1YAKA 1ULXA 1XK2A 1WNVA 4G7PA 3RM5A 1WWMA 3OQLA 1N3UA 1OZWA 1TO9A 2ZVUA 1IVJA 1OZRA 2F2GA 4G99A 4G8WA 1SK7A 1XK3A 1UBBA 3NO6A 1T5PA 1OZLA 1WZDA 4G98A 1P3TA 2QPPA 2Z68A 1WE1A 1P3UA 4GPCA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 5BTQ A;  3HOK A;  1IW1 A;  3MVU A;  4MEC A;  4G7T A;  1OYK A;  4G8P A;  4G8U A;  3BJD A;  1Z72 A;  1XJZ A;  2A2M A;  2A6B A;  3I9T A;  1UDD A;  1WOV A;  2Q32 A;  4WWZ A;  1WOX A;  3B5O A;  1OTW A;  1YAF A;  1IX4 A;  4WWJ A;  2RGZ A;  3I9U A;  4WMH A;  4GOH A;  1V8X A;  3IBX A;  2DY5 A;  3HNH A;  2GM7 A;  3CZY A;  1XK0 A;  2Q4X A;  1IRM A;  4NY7 A;  1IW0 A;  1WNX A;  2GM8 A;  1OZE A;  1P3V A;  2RD3 A;  1OYL A;  1TO9 B;  1S8C A;  4GPF A;  1XK1 A;  1WZF A;  1WOW A;  2A2O A;  1DVE A;  1WZG A;  1IX3 A;  1WNW A;  4WD4 A;  4G7L A;  3MOO A;  4WX0 A;  1RCW A;  1RTW A;  4LQX A;  1TWN A;  3K4F A;  2QCX A;  1NI6 A;  1J77 A;  3I8R A;  4RAJ A;  1S13 A;  1DVG A;  2QZC A;  4FN6 A;  3B5P A;  3HLX A;  1TWR A;  3TGM A;  3HML A;  1N45 A;  1VGI A;  2E7E A;  1OTV A;  1J2C A;  4G7U A;  3DDE A;  4GPH A;  1J02 A;  1TYH A;  1YAK A;  1ULX A;  1XK2 A;  1WNV A;  4G7P A;  3RM5 A;  1WWM A;  3OQL A;  1N3U A;  1OZW A;  1TO9 A;  2ZVU A;  1IVJ A;  1OZR A;  2F2G A;  4G99 A;  4G8W A;  1SK7 A;  1XK3 A;  1UBB A;  3NO6 A;  1T5P A;  1OZL A;  1WZD A;  4G98 A;  1P3T A;  2QPP A;  2Z68 A;  1WE1 A;  1P3U A;  4GPC A; 
#chains in the Genus database with same CATH topology
 5BTQ A;  3HOK A;  1IW1 A;  3MVU A;  4MEC A;  4G7T A;  1OYK A;  4G8P A;  4G8U A;  3BJD A;  1Z72 A;  1XJZ A;  2A2M A;  2A6B A;  3I9T A;  1UDD A;  1WOV A;  2Q32 A;  4WWZ A;  1WOX A;  3B5O A;  1OTW A;  1YAF A;  1IX4 A;  4WWJ A;  2RGZ A;  3I9U A;  4WMH A;  4GOH A;  1V8X A;  3IBX A;  2DY5 A;  3HNH A;  2GM7 A;  3CZY A;  1XK0 A;  2Q4X A;  1IRM A;  4NY7 A;  1IW0 A;  1WNX A;  2GM8 A;  1OZE A;  1P3V A;  2RD3 A;  1OYL A;  1TO9 B;  1S8C A;  4GPF A;  1XK1 A;  1WZF A;  1WOW A;  2A2O A;  1DVE A;  1WZG A;  1IX3 A;  1WNW A;  4WD4 A;  4G7L A;  3MOO A;  4WX0 A;  1RCW A;  1RTW A;  4LQX A;  1TWN A;  3K4F A;  2QCX A;  1NI6 A;  1J77 A;  3I8R A;  4RAJ A;  1S13 A;  1DVG A;  2QZC A;  4FN6 A;  3B5P A;  3HLX A;  1TWR A;  3TGM A;  3HML A;  1N45 A;  1VGI A;  2E7E A;  1OTV A;  2LCU A;  1J2C A;  4G7U A;  3DDE A;  4GPH A;  1J02 A;  1TYH A;  1YAK A;  1ULX A;  1XK2 A;  1WNV A;  4G7P A;  3RM5 A;  1WWM A;  3OQL A;  1N3U A;  1OZW A;  1TO9 A;  2ZVU A;  1IVJ A;  1OZR A;  2F2G A;  4G99 A;  4G8W A;  1SK7 A;  1XK3 A;  1UBB A;  3NO6 A;  1T5P A;  1OZL A;  1WZD A;  4G98 A;  1P3T A;  2QPP A;  2Z68 A;  1WE1 A;  1P3U A;  4GPC A; 
#chains in the Genus database with same CATH homology
 5BTQ A;  3HOK A;  1IW1 A;  3MVU A;  4MEC A;  4G7T A;  1OYK A;  4G8P A;  4G8U A;  3BJD A;  1Z72 A;  1XJZ A;  2A2M A;  2A6B A;  3I9T A;  1UDD A;  1WOV A;  2Q32 A;  4WWZ A;  1WOX A;  3B5O A;  1OTW A;  1YAF A;  1IX4 A;  4WWJ A;  2RGZ A;  3I9U A;  4WMH A;  4GOH A;  1V8X A;  3IBX A;  2DY5 A;  3HNH A;  2GM7 A;  3CZY A;  1XK0 A;  2Q4X A;  1IRM A;  4NY7 A;  1IW0 A;  1WNX A;  2GM8 A;  1OZE A;  1P3V A;  2RD3 A;  1OYL A;  1TO9 B;  1S8C A;  4GPF A;  1XK1 A;  1WZF A;  1WOW A;  2A2O A;  1DVE A;  1WZG A;  1IX3 A;  1WNW A;  4WD4 A;  4G7L A;  3MOO A;  4WX0 A;  1RCW A;  1RTW A;  4LQX A;  1TWN A;  3K4F A;  2QCX A;  1NI6 A;  1J77 A;  3I8R A;  4RAJ A;  1S13 A;  1DVG A;  2QZC A;  4FN6 A;  3B5P A;  3HLX A;  1TWR A;  3TGM A;  3HML A;  1N45 A;  1VGI A;  2E7E A;  1OTV A;  1J2C A;  4G7U A;  3DDE A;  4GPH A;  1J02 A;  1TYH A;  1YAK A;  1ULX A;  1XK2 A;  1WNV A;  4G7P A;  3RM5 A;  1WWM A;  3OQL A;  1N3U A;  1OZW A;  1TO9 A;  2ZVU A;  1IVJ A;  1OZR A;  2F2G A;  4G99 A;  4G8W A;  1SK7 A;  1XK3 A;  1UBB A;  3NO6 A;  1T5P A;  1OZL A;  1WZD A;  4G98 A;  1P3T A;  2QPP A;  2Z68 A;  1WE1 A;  1P3U A;  4GPC A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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