4G8UA

Rat heme oxygenase-1 in complex with heme and o2 with 13 hr illumination: laser off
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
213
structure length
213
Chain Sequence
QDLSEALKEATKEVHIRAENSEFMRNFQKGQVSREGFKLVMASLYHIYTALEEEIERNKQNPVYAPLYFPEELHRRAALEQDMAFWYGPHWQEAIPYTPATQHYVKRLHEVGGTHPELLVAHAYTRYLGDLSGGQVLKKIAQKAMALPSSGEGLAFFTFPSIDNPTKFKQLYRARMNTLEMTPEVKHRVTEEAKTAFLLNIELFEELQALLTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Heme oxygenase 1
publication title Discrimination between CO and O2 in Heme Oxygenase: Comparison of Static Structures and Dynamic Conformation Changes following CO Photolysis
pubmed doi rcsb
source organism Rattus norvegicus
total genus 91
structure length 213
sequence length 213
ec nomenclature ec 1.14.14.18: Heme oxygenase (biliverdin-producing).
pdb deposition date 2012-07-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01126 Heme_oxygenase Heme oxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.910.10 Mainly Alpha Up-down Bundle Heme Oxygenase; Chain A Heme oxygenase-like 4g8uA00
1TYHA 1OZWA 1IW0A 1WZFA 1WZDA 3NO6A 1IVJA 4WMHA 3B5OA 3DDEA 3HLXA 1IX3A 2A6BA 1Z72A 2ZVUA 1J2CA 2RD3A 1S8CA 1TO9A 1YAKA 1XK3A 1TWNA 2GM8A 1S13A 4G8UA 1OTWA 4G8WA 1P3UA 4GPFA 4G99A 1OZEA 4FN6A 4G98A 4WWZA 1J77A 1RTWA 2QZCA 1T5PA 1OYKA 1WWMA 1UDDA 3I9TA 3K4FA 2Q32A 1OTVA 1RCWA 1N3UA 4G7TA 1IRMA 4WD4A 1WOXA 3MVUA 4GPCA 1WOVA 4GOHA 1DVEA 1WOWA 4NY7A 3IBXA 3MOOA 4G7PA 1WNXA 3OQLA 1N45A 1WNWA 1OZLA 1P3VA 4RAJA 2QPPA 1IX4A 2E7EA 1J02A 1OZRA 4GPHA 1OYLA 1XK1A 2QCXA 2A2MA 3CZYA 2A2OA 1TO9B 1XK0A 1DVGA 1VGIA 1SK7A 1NI6A 2RGZA 3BJDA 3B5PA 1XK2A 4WX0A 4G7LA 3HNHA 1P3TA 1WE1A 1ULXA 4G8PA 3RM5A 1YAFA 4WWJA 3HMLA 1XJZA 2Z68A 1V8XA 2F2GA 2GM7A 1UBBA 3I9UA 3I8RA 3HOKA 5BTQA 4G7UA 1WNVA 1TWRA 4MECA 3TGMA 1WZGA 1IW1A 4LQXA 2Q4XA 2DY5A
chains in the Genus database with same CATH superfamily
1TYHA 1OZWA 1IW0A 1WZFA 1WZDA 3NO6A 1IVJA 4WMHA 2LCUA 3B5OA 3DDEA 3HLXA 1IX3A 2A6BA 1Z72A 2ZVUA 1J2CA 2RD3A 1S8CA 1TO9A 1YAKA 1XK3A 1TWNA 2GM8A 1S13A 4G8UA 1OTWA 4G8WA 1P3UA 4GPFA 4G99A 1OZEA 4FN6A 4G98A 4WWZA 1J77A 1RTWA 2QZCA 1T5PA 1OYKA 1WWMA 1UDDA 3I9TA 3K4FA 2Q32A 1OTVA 1RCWA 1N3UA 4G7TA 1IRMA 4WD4A 1WOXA 3MVUA 4GPCA 1WOVA 4GOHA 1DVEA 1WOWA 4NY7A 3IBXA 3MOOA 4G7PA 1WNXA 3OQLA 1N45A 1WNWA 1OZLA 1P3VA 4RAJA 2QPPA 1IX4A 2E7EA 1J02A 1OZRA 4GPHA 1OYLA 1XK1A 2QCXA 2A2MA 3CZYA 2A2OA 1TO9B 1XK0A 1DVGA 1VGIA 1SK7A 1NI6A 2RGZA 3BJDA 3B5PA 1XK2A 4WX0A 4G7LA 3HNHA 1P3TA 1WE1A 1ULXA 4G8PA 3RM5A 1YAFA 4WWJA 3HMLA 1XJZA 2Z68A 1V8XA 2F2GA 2GM7A 1UBBA 3I9UA 3I8RA 3HOKA 5BTQA 4G7UA 1WNVA 1TWRA 4MECA 3TGMA 1WZGA 1IW1A 4LQXA 2Q4XA 2DY5A
chains in the Genus database with same CATH topology
1TYHA 1OZWA 1IW0A 1WZFA 1WZDA 3NO6A 1IVJA 4WMHA 3B5OA 3DDEA 3HLXA 1IX3A 2A6BA 1Z72A 2ZVUA 1J2CA 2RD3A 1S8CA 1TO9A 1YAKA 1XK3A 1TWNA 2GM8A 1S13A 4G8UA 1OTWA 4G8WA 1P3UA 4GPFA 4G99A 1OZEA 4FN6A 4G98A 4WWZA 1J77A 1RTWA 2QZCA 1T5PA 1OYKA 1WWMA 1UDDA 3I9TA 3K4FA 2Q32A 1OTVA 1RCWA 1N3UA 4G7TA 1IRMA 4WD4A 1WOXA 3MVUA 4GPCA 1WOVA 4GOHA 1DVEA 1WOWA 4NY7A 3IBXA 3MOOA 4G7PA 1WNXA 3OQLA 1N45A 1WNWA 1OZLA 1P3VA 4RAJA 2QPPA 1IX4A 2E7EA 1J02A 1OZRA 4GPHA 1OYLA 1XK1A 2QCXA 2A2MA 3CZYA 2A2OA 1TO9B 1XK0A 1DVGA 1VGIA 1SK7A 1NI6A 2RGZA 3BJDA 3B5PA 1XK2A 4WX0A 4G7LA 3HNHA 1P3TA 1WE1A 1ULXA 4G8PA 3RM5A 1YAFA 4WWJA 3HMLA 1XJZA 2Z68A 1V8XA 2F2GA 2GM7A 1UBBA 3I9UA 3I8RA 3HOKA 5BTQA 4G7UA 1WNVA 1TWRA 4MECA 3TGMA 1WZGA 1IW1A 4LQXA 2Q4XA 2DY5A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1TYH A;  1OZW A;  1IW0 A;  1WZF A;  1WZD A;  3NO6 A;  1IVJ A;  4WMH A;  3B5O A;  3DDE A;  3HLX A;  1IX3 A;  2A6B A;  1Z72 A;  2ZVU A;  1J2C A;  2RD3 A;  1S8C A;  1TO9 A;  1YAK A;  1XK3 A;  1TWN A;  2GM8 A;  1S13 A;  4G8U A;  1OTW A;  4G8W A;  1P3U A;  4GPF A;  4G99 A;  1OZE A;  4FN6 A;  4G98 A;  4WWZ A;  1J77 A;  1RTW A;  2QZC A;  1T5P A;  1OYK A;  1WWM A;  1UDD A;  3I9T A;  3K4F A;  2Q32 A;  1OTV A;  1RCW A;  1N3U A;  4G7T A;  1IRM A;  4WD4 A;  1WOX A;  3MVU A;  4GPC A;  1WOV A;  4GOH A;  1DVE A;  1WOW A;  4NY7 A;  3IBX A;  3MOO A;  4G7P A;  1WNX A;  3OQL A;  1N45 A;  1WNW A;  1OZL A;  1P3V A;  4RAJ A;  2QPP A;  1IX4 A;  2E7E A;  1J02 A;  1OZR A;  4GPH A;  1OYL A;  1XK1 A;  2QCX A;  2A2M A;  3CZY A;  2A2O A;  1TO9 B;  1XK0 A;  1DVG A;  1VGI A;  1SK7 A;  1NI6 A;  2RGZ A;  3BJD A;  3B5P A;  1XK2 A;  4WX0 A;  4G7L A;  3HNH A;  1P3T A;  1WE1 A;  1ULX A;  4G8P A;  3RM5 A;  1YAF A;  4WWJ A;  3HML A;  1XJZ A;  2Z68 A;  1V8X A;  2F2G A;  2GM7 A;  1UBB A;  3I9U A;  3I8R A;  3HOK A;  5BTQ A;  4G7U A;  1WNV A;  1TWR A;  4MEC A;  3TGM A;  1WZG A;  1IW1 A;  4LQX A;  2Q4X A;  2DY5 A; 
#chains in the Genus database with same CATH topology
 1TYH A;  1OZW A;  1IW0 A;  1WZF A;  1WZD A;  3NO6 A;  1IVJ A;  4WMH A;  2LCU A;  3B5O A;  3DDE A;  3HLX A;  1IX3 A;  2A6B A;  1Z72 A;  2ZVU A;  1J2C A;  2RD3 A;  1S8C A;  1TO9 A;  1YAK A;  1XK3 A;  1TWN A;  2GM8 A;  1S13 A;  4G8U A;  1OTW A;  4G8W A;  1P3U A;  4GPF A;  4G99 A;  1OZE A;  4FN6 A;  4G98 A;  4WWZ A;  1J77 A;  1RTW A;  2QZC A;  1T5P A;  1OYK A;  1WWM A;  1UDD A;  3I9T A;  3K4F A;  2Q32 A;  1OTV A;  1RCW A;  1N3U A;  4G7T A;  1IRM A;  4WD4 A;  1WOX A;  3MVU A;  4GPC A;  1WOV A;  4GOH A;  1DVE A;  1WOW A;  4NY7 A;  3IBX A;  3MOO A;  4G7P A;  1WNX A;  3OQL A;  1N45 A;  1WNW A;  1OZL A;  1P3V A;  4RAJ A;  2QPP A;  1IX4 A;  2E7E A;  1J02 A;  1OZR A;  4GPH A;  1OYL A;  1XK1 A;  2QCX A;  2A2M A;  3CZY A;  2A2O A;  1TO9 B;  1XK0 A;  1DVG A;  1VGI A;  1SK7 A;  1NI6 A;  2RGZ A;  3BJD A;  3B5P A;  1XK2 A;  4WX0 A;  4G7L A;  3HNH A;  1P3T A;  1WE1 A;  1ULX A;  4G8P A;  3RM5 A;  1YAF A;  4WWJ A;  3HML A;  1XJZ A;  2Z68 A;  1V8X A;  2F2G A;  2GM7 A;  1UBB A;  3I9U A;  3I8R A;  3HOK A;  5BTQ A;  4G7U A;  1WNV A;  1TWR A;  4MEC A;  3TGM A;  1WZG A;  1IW1 A;  4LQX A;  2Q4X A;  2DY5 A; 
#chains in the Genus database with same CATH homology
 1TYH A;  1OZW A;  1IW0 A;  1WZF A;  1WZD A;  3NO6 A;  1IVJ A;  4WMH A;  3B5O A;  3DDE A;  3HLX A;  1IX3 A;  2A6B A;  1Z72 A;  2ZVU A;  1J2C A;  2RD3 A;  1S8C A;  1TO9 A;  1YAK A;  1XK3 A;  1TWN A;  2GM8 A;  1S13 A;  4G8U A;  1OTW A;  4G8W A;  1P3U A;  4GPF A;  4G99 A;  1OZE A;  4FN6 A;  4G98 A;  4WWZ A;  1J77 A;  1RTW A;  2QZC A;  1T5P A;  1OYK A;  1WWM A;  1UDD A;  3I9T A;  3K4F A;  2Q32 A;  1OTV A;  1RCW A;  1N3U A;  4G7T A;  1IRM A;  4WD4 A;  1WOX A;  3MVU A;  4GPC A;  1WOV A;  4GOH A;  1DVE A;  1WOW A;  4NY7 A;  3IBX A;  3MOO A;  4G7P A;  1WNX A;  3OQL A;  1N45 A;  1WNW A;  1OZL A;  1P3V A;  4RAJ A;  2QPP A;  1IX4 A;  2E7E A;  1J02 A;  1OZR A;  4GPH A;  1OYL A;  1XK1 A;  2QCX A;  2A2M A;  3CZY A;  2A2O A;  1TO9 B;  1XK0 A;  1DVG A;  1VGI A;  1SK7 A;  1NI6 A;  2RGZ A;  3BJD A;  3B5P A;  1XK2 A;  4WX0 A;  4G7L A;  3HNH A;  1P3T A;  1WE1 A;  1ULX A;  4G8P A;  3RM5 A;  1YAF A;  4WWJ A;  3HML A;  1XJZ A;  2Z68 A;  1V8X A;  2F2G A;  2GM7 A;  1UBB A;  3I9U A;  3I8R A;  3HOK A;  5BTQ A;  4G7U A;  1WNV A;  1TWR A;  4MEC A;  3TGM A;  1WZG A;  1IW1 A;  4LQX A;  2Q4X A;  2DY5 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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