The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
199
|
sequence length |
606
|
structure length |
606
|
Chain Sequence |
ADPSSFASPEKFNIKHMHLKLHVDFTSRAIAASTSLTVRSLQDSLASLILDTKDLTIKKVAVNGKDATFALGTTHSFKGTPLEITLPFSLTRGQEVIVEIDSVTSPKSSALQWLNKEQTAGKIHPYLFSQCQATHCRSIIPCQDTPSVKFTYYSQVSVPKELMALMSALRDGELSEQSDSNRKIYRFKQNVPIPSYLIALVVGALEGRKVGPRTTIWTEKELLEPSVYEFAETEKMLKYAEDLAGPYVWGQYDLLILPPSFPYGGMENPCLTFVTPTVLAGDRSLASVIAHEISHSWTGNLVTNETWENFWLNEGHTVYLERRIDGRLYGEEFRQFKALGGWKELQNSVNTFGATNPLTNLVPNLHEVDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFLGFLKSYIQMFAFKSVTTEEWKKFLYSYFKDKVDILDKVDWKGWMHTPGMPPVQPKYDMTLANACITLGQKWVKATESDLGSFSADDVKDLSSHQLIEVLAILLLEKPLPVSHVKRMQEVYNLNDVKNSEIRFRWLRLCIRAGWEDVIPLALAMATEQGRMKFTRPLYRDLYNFEKAREQTVNTFLKNRSFMHPVTEMLVAKDLHIS
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Product formation controlled by substrate dynamics in leukotriene A4 hydrolase.
pubmed doi rcsb |
| molecule keywords |
MGC78867 protein
|
| molecule tags |
Hydrolase/hydrolase inhibitor
|
| source organism |
Xenopus laevis
|
| total genus |
199
|
| structure length |
606
|
| sequence length |
606
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
3.3.2.6: Leukotriene-A(4) hydrolase. |
| pdb deposition date | 2012-07-25 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01433 | Peptidase_M1 | Peptidase family M1 domain |
| A | PF09127 | Leuk-A4-hydro_C | Leukotriene A4 hydrolase, C-terminal |
| A | PF17900 | Peptidase_M1_N | Peptidase M1 N-terminal domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Neutral Protease; domain 2 | Neutral Protease Domain 2 | ||
| Mainly Alpha | Orthogonal Bundle | Rna Polymerase Sigma Factor; Chain: A | Rna Polymerase Sigma Factor; Chain: A | ||
| Mainly Alpha | Alpha Horseshoe | Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat | Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat | ||
| Mainly Beta | Sandwich | Immunoglobulin-like | tricorn interacting facor f3 domain |
