4GB1A

Synthesis and evaluation of novel 3-c-alkylated-neu5ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
387
structure length
387
Chain Sequence
TYMNNTEAICDAKGFAPFSKDNGIRIGSRGHIFVIREPFVSCSPIECRTFFLTQGSLLNDKHSNGTVKDRSPFRTLMSVEVGQSPNVYQARFEAVAWSATACHDGKKWMTVGVTGPDSKAVAVIHYGGVPTDVVNSWAGDILRTQESSCTCIQGDCYWVMTDGPANRQAQYRIYKANQGRIIGQTDISFNGGHIEECSCYPNDGKVECVCRDNWTGTNRPVLVISPDLSYRVGYLCAGIPSDTPRGEDTQFTGSCTSPMGNQGYGVKGFGFRQGTDVWMGRTISRTSRSGFEILRIKNGWTQTSKEQIRKQVVVDNLNWSGYSGSFTLPVELSGKDCLVPCFWVEMIRGKPEEKTIWTSSSSIVMCGVDYEVADWSWHDGAILPFDI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Neuraminidase
total genus 103
structure length 387
sequence length 387
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 2012-07-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00064 Neur Neuraminidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 4gb1A00
2ZB6A 2VVZA 3TI8A 3TI6A 4UF7A 4CPOA 5M1ZA 1Z4WA 1V3BA 5HX0A 1IVBA 2SILA 4XE9A 1W0OA 4FPKA 4MWUA 1N1SA 4B7JA 2CMLA 3B7EA 2QWBA 1NCDN 4CPLA 1N1VA 1NSDA 1S0JA 4M4UA 4QN4A 4HZVA 1XOGA 2A75A 4FP3A 1NNBA 3SALA 4YW5A 4FPOB 4GZTA 2HTQA 5NN9A 4FOYA 3K38A 1VCUA 4GDIA 4YW2A 2VW0A 4FPJA 1NSCA 4FPFA 2ZB5A 1NSBA 4FQ4A 4MWRA 2QWJA 3A71A 4K1JA 2BATA 4MWWA 4HZZA 4MX0A 2F24A 4XIKA 3D12A 2XCYA 4B7NA 1W20A 1V0ZA 1NNCA 4XIOA 1A14N 1E8VA 2F13A 1A4QA 2F25A 1DIMA 2F27A 1INFA 2SIMA 1EUUA 2YDPA 4XJUA 1N1YA 1EUSA 2VK5A 3CL0A 1EURA 4B7MA 2YA6A 3T1EA 4FOVA 4Q6KA 1SLIA 4XJAA 1Z50A 4GZSA 3A72A 2YA7A 4FPGA 1INYA 1V2IA 1IVFA 1Z4ZA 1NMCA 2AGSA 6NN9A 2QWAA 2JKBA 4XILA 4FOWA 3K39A 3H72A 3TIAA 3D11A 4NCSA 1USXA 1L7GA 4DGRA 4XHBA 3ALWA 3JU4A 1B9TA 7NN9A 1F8CA 4K1IA 2F28A 4JF7A 4WA3A 1MR5A 2AEQA 1VCJA 3GVKA 4YZ4A 1W8NA 4WEGA 4XJRA 4XMAA 2QWHA 4MC7A 1V0FA 1L7FA 3K36A 2VSKA 2VK6A 2C4LA 1NCAN 2SLIA 4K1HA 1NMAN 3GVJA 4GZXA 3H73A 1XOEA 3H6JA 2W20A 4KS4A 1E8TA 3BEQA 2XZKA 4J9TA 2W38A 4FPLA 4WA4A 4QN7A 3W09A 1NN2A 4MJUA 2VK7A 1NCBN 4GZQA 1W1XA 1MS0A 4FPHA 1IVDA 3CL2A 1WCQA 1E8UA 1MS8A 4YW4A 5F9TA 1NNAA 4CPZA 4FPEA 4QN5A 4HZYA 1SO7A 3B69A 2B8HA 4M3MA 3INBA 2QWEA 4GZOA 2HT5A 2W5OA 4KS3A 3OPZA 4FPCA 1F8BA 1MZ5A 2YA5A 1IVCA 4K1KA 2VW2A 4HZXA 1MZ6A 1USRA 4YW3A 4CPNA 2F26A 1W21A 4QN6A 4X6KA 1Z4VA 2AH2A 4MWQA 2F11A 4GJTA 4K3YA 3CYEA 4FP2A 3K3AA 1S0IA 2VWDA 3NN9A 2QWKA 2HTRA 3H71A 4FJ6A 4FPYA 4SLIA 1BJIA 2BZDA 2HT7A 2HU0A 2HTUA 4XYXA 4MJVA 4B7QA 4M4VA 4GB1A 2F0ZA 2HT8A 1IVEA 2QWIA 3TI3A 1WCSA 4X4AA 2XZIA 4M4NA 2BF6A 1MS1A 4FZHA 2HTYA 4MWYA 2BERA 2VSMA 4KS2A 4XJ8A 1F8EA 4MZAA 2QWCA 3O9JA 1INWA 4BBWA 4QNPA 5B2DA 4GZPA 2F29A 1DILA 2C4AA 1A4GA 2HTWA 4I00A 4FOQA 5B2CA 1INGA 1W0PA 2F12A 1EUTA 2F10A 3GVLA 2HU4A 3TI4A 4B7RA 1IVGA 4MWXA 4HIZA 1SLLA 1W8OA 4H52A 4MZEA 1V3EA 4GZWA 4YW1A 1NMBN 2QWFA 5HUMA 2YDTA 4YZ5A 4CPMA 3K37A 1F8DA 3ALXA 4MWLA 2QWDA 4XMIA 1Z4YA 4QN3A 4X47A 4KS5A 4NN9A 2QWGA 2RKCA 2VW1A 3TIBA 4YZ1A 4XJQA 2YA8A 2XZJA 5JYYA 4YZ3A 4H53A 1MS4A 4NC5A 3SLIA 4KS1A 1NCCN 3SANA 1MWEA 1MS3A 1MS9A 4MWVA 4WEFA 4XJZA 5HUKA 4XJWA 1V3DA 4X49A 4WA5A 1INVA 4D8SA 1N1TA 2AEPA 3O9KA 1Z4XA 3CKZA 2YA4A 5HUNA 1KITA 4GDJA 3PJQA 3NSSA 3TICA 4XHXA 2W5NA 4MWJA 4HZWA 4XJ9A 1INXA 2FHRA 4FVKA 4YZ2A 2X9MA 4CPYA 1INHA 1B9SA 5HUGA 2HTVA 1L7HA 1V0EA 3SILA 1MS5A 4XOGA 1SNTA 3TI5A 1V3CA 1B9VA 4GEZA
chains in the Genus database with same CATH superfamily
2ZB6A 2VVZA 2GVXA 2W8BA 3TI8A 3TI6A 4AHAA 3P5BL 5GX1A 4UF7A 3S8ZA 4CPOA 5M1ZA 1Z4WA 1V3BA 5FNSA 1IVBA 2SILA 3VNHA 5HX0A 4XE9A 1W0OA 4FPKA 4MWUA 4PWZA 1N1SA 4B7JA 2CMLA 3B7EA 2QWBA 1NCDN 4CPLA 2IAUA 3AMRA 4GNAA 1NSDA 1S0JA 4M4UA 4QN4A 4D52B 4HZVA 3S8VA 1XOGA 2A75A 4FP3A 1NNBA 3SALA 5CGJA 4YW5A 4FPOB 4GZTA 2HTQA 5NN9A 4FOYA 1S18A 1ZI0A 3K38A 1VCUA 4GDIA 4YW2A 2VW0A 4FPJA 1NSCA 1POOA 4FPFA 2ZB5A 1NSBA 4C1YB 4FQ4A 4MWRA 2OJHA 4D4UA 1E1AA 4CHBA 1PJXA 3WN7A 3I1CA 2ZW9A 4L7BA 2QWJA 3A71A 4K1JA 2BATA 4MWWA 3ADEA 4HZZA 4MX0A 2F24A 4XIKA 3D12A 2XCYA 4B7NA 1W20A 1V0ZA 1NNCA 1CRZA 4XIOA 1A14N 1E8VA 2F13A 1A4QA 2F25A 3WW9A 4HW6A 4UOUA 1DIMA 2F27A 4JMLA 1INFA 2GVWA 2SIMA 1EUUA 2YDPA 4XJUA 1N1YA 1EUSA 2VK5A 2ZWAA 2IAVA 3CL0A 4GNBA 3SOQA 1EURA 4CSDA 4B7MA 3O4PA 2YA6A 2IAPA 3T1EA 3LI4A 4N1BA 4FOVA 3HLHA 3V64C 4O5TA 4Q6KA 2DSOA 4IFJA 1SLIA 4XJAA 1Z50A 1U6DX 4D52A 4GZSA 4A0PA 3A72A 2YA7A 1H6LA 4FPGA 1INYA 1V2IA 1IVFA 2VAQA 1Z4ZA 4ZY3A 1QLGA 1NMCA 2AGSA 2H2NA 6NN9A 2QWAA 2JKBA 2IAWA 4XILA 4FOWA 3K39A 3H72A 3S2KA 3TIAA 3D11A 4NCSA 1USXA 1L7GA 4DGRA 4XHBA 3ALWA 3JU4A 3FVZA 5H47A 1B9TA 4AH4A 7NN9A 1F8CA 4K1IA 2F28A 4JF7A 4WA3A 1MR5A 2AEQA 1VCJA 4IMBA 3GVKA 3UC1A 4YZ4A 1WP5A 3SRGA 3SOVA 1W8NA 4WEGA 4XJRA 4XMAA 2QWHA 4MC7A 1V0FA 1L7FA 3K36A 2VSKA 1OFZA 2VK6A 2C4LA 1NCAN 2GHSA 3KYAA 1S1DA 4IYGA 2SLIA 4K1HA 4AGIA 1NMAN 1NPEA 3NO0A 3GVJA 4GZXA 3H73A 1XOEA 5EO8A 2DYHA 3ZGCA 1N6FA 1RWLA 1IUCA 2V91A 3H6JA 4GN8A 2IASA 4DG6A 2W20A 4KS4A 1CVMA 1E8TA 3BEQA 2XZKA 4J9TA 2W38A 4G3NA 4FPLA 4WA4A 4QN7A 3W09A 2FP9A 1N6EA 1NN2A 4MJUA 2VK7A 1NCBN 1N6DA 3FW0A 4GZQA 2FPBA 2POOA 1W1XA 1MS0A 4FPHA 1IVDA 5FNRA 3DASA 2VPJA 2H2UA 4ZLRA 3CL2A 3S94A 1WCQA 1E8UA 1MS8A 3G4HA 3WWAA 4YW4A 5F9TA 2FP8A 1NNAA 4CPZA 4FPEA 4QN5A 4HZYA 5EO7A 1SO7A 2P4OA 2B8HA 3B69A 4M3MA 3INBA 4ZGCA 5D9DA 1CQ1A 2QWEA 4GZOA 2HT5A 2W5OA 4HHQA 4KS3A 3OPZA 4FPCA 1F8BA 1MZ5A 2YA5A 1IVCA 4K1KA 2VW2A 4HZXA 1MZ6A 1USRA 4YW3A 4GNCA 4CPNA 2F26A 1W21A 4QN6A 2FLUX 4X6KA 1Z4VA 2AH2A 4MWQA 3V1SA 2F11A 1RWIA 4GJTA 4K3YA 3CYEA 4FP2A 3K3AA 4ASCA 3IAXA 1S0IA 3V65B 2QE8A 2VWDA 3NN9A 2QWKA 2HTRA 3H71A 4FJ6A 3G4EA 1X2JA 2Z32A 2GVVA 4FPYA 4SLIA 1BJIA 1SUUA 2IVZA 2BZDA 2HT7A 3DR2A 4C1YA 2HU0A 3II7A 2HTUA 4IFLX 3KGGA 4XYXA 4MJVA 4B7QA 4M4VA 4GB1A 2F0ZA 3ZGDA 2HT8A 1N7DA 5GX5A 1C5KA 1IVEA 3AMSA 2IATA 4YY8A 2QWIA 3TI3A 1WCSA 1C9UA 4X4AA 2XZIA 1ZGKA 4M4NA 2BF6A 1MS1A 4FZHA 2XN4A 2ISMA 2HTYA 4MWYA 2BERA 2VSMA 4KS2A 4XJ8A 2IARA 1F8EA 4IQKA 4MZAA 2QWCA 3O9JA 1K32A 4GEZA 5GX2A 1INWA 4BBWA 4QNPA 5GTQA 5B2DA 4GZPA 2F29A 1DILA 2C4AA 1A4GA 1IJQA 2HTWA 4I00A 4D52C 2IAQA 4FOQA 1Q7FA 2WOZA 5B2CA 2DG0A 1V04A 1INGA 1W0PA 2F12A 1EUTA 4HHOA 3BYCA 2F10A 3GVLA 5FNQA 2HU4A 3TI4A 5FNUA 2HQSA 4B7RA 5GX4A 1IVGA 3U0SA 4MWXA 4HIZA 1SLLA 1W8OA 4H52A 4MZEA 1V3EA 5FZNA 4GZWA 4YW1A 1NMBN 4IFNX 4Q1UA 2QWFA 5HUMA 2YDTA 4O5SA 2G8SA 3A9HA 3HLIA 4YZ5A 4CPMA 2W8BB 5FZJA 3K37A 1F8DA 2IAOA 3ALXA 4MWLA 2QWDA 4XMIA 3Q6TA 1Z4YA 4QN3A 4X47A 5FWWA 2ZZKA 5F72C 4KS5A 3Q6KA 4NN9A 2QWGA 2RKCA 2VW1A 3TIBA 4YZ1A 4XJQA 2YA8A 5FNTA 3HRPA 2XZJA 5JYYA 3SOBB 4YZ3A 1QBIA 4H53A 2DG1A 1MS4A 4NC5A 4GN9A 3SLIA 2FPCA 4KS1A 1NCCN 2GVUA 1IUBA 5D9CA 4AGTA 3SANA 1MWEA 1MS3A 1MS9A 4MWVA 4WEFA 1CRUA 4XJZA 2IAXA 5HUKA 4XJWA 1V3DA 4X49A 4WA5A 3Q6PA 1INVA 4D8SA 1N1TA 3LI5A 2AEPA 3L6VA 3O9KA 4IN4A 3TC9A 3LI3A 1Z4XA 4L7CA 3CKZA 3A9GA 2YA4A 5HUNA 1KITA 5D9BA 4GDJA 3VNGA 3PJQA 4R40A 3NSSA 3TICA 4XHXA 2W5NA 4MWJA 4HZWA 4XJ9A 1INXA 4CH9A 2FHRA 4FVKA 4YZ2A 1X2RA 2X9MA 3E5ZA 4CPYA 3SREA 1INHA 1B9SA 5HUGA 2HTVA 1L7HA 1V0EA 3SILA 5EX7A 3WDZA 1MS5A 4XOGA 5GX3A 1SNTA 3TI5A 4GN7A 4XMBA 1V3CA 1B9VA 1N1VA 4L7DA
chains in the Genus database with same CATH topology
2ZB6A 2VVZA 3TI8A 3TI6A 4UF7A 4CPOA 5M1ZA 1Z4WA 1V3BA 5HX0A 1IVBA 2SILA 4XE9A 1W0OA 4FPKA 4MWUA 1N1SA 4B7JA 2CMLA 3B7EA 2QWBA 1NCDN 4CPLA 1N1VA 1NSDA 1S0JA 4M4UA 4QN4A 4HZVA 1XOGA 2A75A 4FP3A 1NNBA 3SALA 4YW5A 4FPOB 4GZTA 2HTQA 5NN9A 4FOYA 1S18A 3K38A 1VCUA 4GDIA 4YW2A 2VW0A 4FPJA 1NSCA 4FPFA 2ZB5A 1NSBA 4FQ4A 4MWRA 2QWJA 3A71A 4K1JA 2BATA 4MWWA 4HZZA 4MX0A 2F24A 4XIKA 3D12A 2XCYA 4B7NA 1W20A 1V0ZA 1NNCA 4XIOA 1A14N 1E8VA 2F13A 1A4QA 2F25A 1DIMA 2F27A 1INFA 2SIMA 1EUUA 2YDPA 4XJUA 1N1YA 1EUSA 2VK5A 3CL0A 1EURA 4B7MA 2YA6A 3T1EA 4FOVA 4Q6KA 1SLIA 4XJAA 1Z50A 4GZSA 3A72A 2YA7A 4FPGA 1INYA 1V2IA 1IVFA 1Z4ZA 1NMCA 2AGSA 2H2NA 6NN9A 2QWAA 2JKBA 4XILA 4FOWA 3K39A 3H72A 3TIAA 3D11A 4NCSA 1USXA 1L7GA 4DGRA 4XHBA 3ALWA 3JU4A 1B9TA 7NN9A 1F8CA 4K1IA 2F28A 4JF7A 4WA3A 1MR5A 2AEQA 1VCJA 3GVKA 4YZ4A 1W8NA 4WEGA 4XJRA 4XMAA 2QWHA 4MC7A 1V0FA 1L7FA 3K36A 2VSKA 2VK6A 2C4LA 1NCAN 1S1DA 2SLIA 4K1HA 1NMAN 3GVJA 4GZXA 3H73A 1XOEA 3H6JA 2W20A 4KS4A 1E8TA 3BEQA 2XZKA 4J9TA 2W38A 4FPLA 4WA4A 4QN7A 3W09A 1NN2A 4MJUA 2VK7A 1NCBN 4GZQA 1W1XA 1MS0A 4FPHA 1IVDA 2H2UA 3CL2A 1WCQA 1E8UA 1MS8A 4YW4A 5F9TA 1NNAA 4CPZA 4FPEA 4QN5A 4HZYA 1SO7A 3B69A 2B8HA 4M3MA 3INBA 2QWEA 4GZOA 2HT5A 2W5OA 4KS3A 3OPZA 4FPCA 1F8BA 1MZ5A 2YA5A 1IVCA 4K1KA 2VW2A 4HZXA 1MZ6A 1USRA 4YW3A 4CPNA 2F26A 1W21A 4QN6A 4X6KA 1Z4VA 2AH2A 4MWQA 2F11A 4GJTA 4K3YA 3CYEA 4FP2A 3K3AA 1S0IA 2VWDA 3NN9A 2QWKA 2HTRA 3H71A 4FJ6A 4FPYA 4SLIA 1BJIA 2BZDA 2HT7A 2HU0A 2HTUA 4XYXA 4MJVA 4B7QA 4M4VA 4GB1A 2F0ZA 2HT8A 1IVEA 2QWIA 3TI3A 1WCSA 4X4AA 2XZIA 4M4NA 2BF6A 1MS1A 4FZHA 2HTYA 4MWYA 2BERA 2VSMA 4KS2A 4XJ8A 1F8EA 4MZAA 2QWCA 3O9JA 1INWA 4BBWA 4QNPA 5B2DA 4GZPA 2F29A 1DILA 2C4AA 1A4GA 2HTWA 4I00A 4FOQA 5B2CA 1INGA 1W0PA 2F12A 1EUTA 2F10A 3GVLA 2HU4A 3TI4A 4B7RA 1IVGA 4MWXA 4HIZA 1SLLA 1W8OA 4H52A 4MZEA 1V3EA 4GZWA 4YW1A 1NMBN 2QWFA 5HUMA 2YDTA 4YZ5A 4CPMA 3K37A 1F8DA 3ALXA 4MWLA 2QWDA 4XMIA 1Z4YA 4QN3A 4X47A 4KS5A 4NN9A 2QWGA 2RKCA 2VW1A 3TIBA 4YZ1A 4XJQA 2YA8A 2XZJA 5JYYA 4YZ3A 4H53A 1MS4A 4NC5A 3SLIA 4KS1A 1NCCN 3SANA 1MWEA 1MS3A 1MS9A 4MWVA 4WEFA 4XJZA 5HUKA 4XJWA 1V3DA 4X49A 4WA5A 1INVA 4D8SA 1N1TA 2AEPA 3O9KA 1Z4XA 3CKZA 2YA4A 5HUNA 1KITA 4GDJA 3PJQA 3NSSA 3TICA 4XHXA 2W5NA 4MWJA 4HZWA 4XJ9A 1INXA 2FHRA 4FVKA 4YZ2A 2X9MA 4CPYA 1INHA 1B9SA 5HUGA 2HTVA 1L7HA 1V0EA 3SILA 1MS5A 4XOGA 1SNTA 3TI5A 1V3CA 1B9VA 4GEZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZB6 A;  2VVZ A;  3TI8 A;  3TI6 A;  4UF7 A;  4CPO A;  5M1Z A;  1Z4W A;  1V3B A;  5HX0 A;  1IVB A;  2SIL A;  4XE9 A;  1W0O A;  4FPK A;  4MWU A;  1N1S A;  4B7J A;  2CML A;  3B7E A;  2QWB A;  1NCD N;  4CPL A;  1N1V A;  1NSD A;  1S0J A;  4M4U A;  4QN4 A;  4HZV A;  1XOG A;  2A75 A;  4FP3 A;  1NNB A;  3SAL A;  4YW5 A;  4FPO B;  4GZT A;  2HTQ A;  5NN9 A;  4FOY A;  3K38 A;  1VCU A;  4GDI A;  4YW2 A;  2VW0 A;  4FPJ A;  1NSC A;  4FPF A;  2ZB5 A;  1NSB A;  4FQ4 A;  4MWR A;  2QWJ A;  3A71 A;  4K1J A;  2BAT A;  4MWW A;  4HZZ A;  4MX0 A;  2F24 A;  4XIK A;  3D12 A;  2XCY A;  4B7N A;  1W20 A;  1V0Z A;  1NNC A;  4XIO A;  1A14 N;  1E8V A;  2F13 A;  1A4Q A;  2F25 A;  1DIM A;  2F27 A;  1INF A;  2SIM A;  1EUU A;  2YDP A;  4XJU A;  1N1Y A;  1EUS A;  2VK5 A;  3CL0 A;  1EUR A;  4B7M A;  2YA6 A;  3T1E A;  4FOV A;  4Q6K A;  1SLI A;  4XJA A;  1Z50 A;  4GZS A;  3A72 A;  2YA7 A;  4FPG A;  1INY A;  1V2I A;  1IVF A;  1Z4Z A;  1NMC A;  2AGS A;  6NN9 A;  2QWA A;  2JKB A;  4XIL A;  4FOW A;  3K39 A;  3H72 A;  3TIA A;  3D11 A;  4NCS A;  1USX A;  1L7G A;  4DGR A;  4XHB A;  3ALW A;  3JU4 A;  1B9T A;  7NN9 A;  1F8C A;  4K1I A;  2F28 A;  4JF7 A;  4WA3 A;  1MR5 A;  2AEQ A;  1VCJ A;  3GVK A;  4YZ4 A;  1W8N A;  4WEG A;  4XJR A;  4XMA A;  2QWH A;  4MC7 A;  1V0F A;  1L7F A;  3K36 A;  2VSK A;  2VK6 A;  2C4L A;  1NCA N;  2SLI A;  4K1H A;  1NMA N;  3GVJ A;  4GZX A;  3H73 A;  1XOE A;  3H6J A;  2W20 A;  4KS4 A;  1E8T A;  3BEQ A;  2XZK A;  4J9T A;  2W38 A;  4FPL A;  4WA4 A;  4QN7 A;  3W09 A;  1NN2 A;  4MJU A;  2VK7 A;  1NCB N;  4GZQ A;  1W1X A;  1MS0 A;  4FPH A;  1IVD A;  3CL2 A;  1WCQ A;  1E8U A;  1MS8 A;  4YW4 A;  5F9T A;  1NNA A;  4CPZ A;  4FPE A;  4QN5 A;  4HZY A;  1SO7 A;  3B69 A;  2B8H A;  4M3M A;  3INB A;  2QWE A;  4GZO A;  2HT5 A;  2W5O A;  4KS3 A;  3OPZ A;  4FPC A;  1F8B A;  1MZ5 A;  2YA5 A;  1IVC A;  4K1K A;  2VW2 A;  4HZX A;  1MZ6 A;  1USR A;  4YW3 A;  4CPN A;  2F26 A;  1W21 A;  4QN6 A;  4X6K A;  1Z4V A;  2AH2 A;  4MWQ A;  2F11 A;  4GJT A;  4K3Y A;  3CYE A;  4FP2 A;  3K3A A;  1S0I A;  2VWD A;  3NN9 A;  2QWK A;  2HTR A;  3H71 A;  4FJ6 A;  4FPY A;  4SLI A;  1BJI A;  2BZD A;  2HT7 A;  2HU0 A;  2HTU A;  4XYX A;  4MJV A;  4B7Q A;  4M4V A;  4GB1 A;  2F0Z A;  2HT8 A;  1IVE A;  2QWI A;  3TI3 A;  1WCS A;  4X4A A;  2XZI A;  4M4N A;  2BF6 A;  1MS1 A;  4FZH A;  2HTY A;  4MWY A;  2BER A;  2VSM A;  4KS2 A;  4XJ8 A;  1F8E A;  4MZA A;  2QWC A;  3O9J A;  1INW A;  4BBW A;  4QNP A;  5B2D A;  4GZP A;  2F29 A;  1DIL A;  2C4A A;  1A4G A;  2HTW A;  4I00 A;  4FOQ A;  5B2C A;  1ING A;  1W0P A;  2F12 A;  1EUT A;  2F10 A;  3GVL A;  2HU4 A;  3TI4 A;  4B7R A;  1IVG A;  4MWX A;  4HIZ A;  1SLL A;  1W8O A;  4H52 A;  4MZE A;  1V3E A;  4GZW A;  4YW1 A;  1NMB N;  2QWF A;  5HUM A;  2YDT A;  4YZ5 A;  4CPM A;  3K37 A;  1F8D A;  3ALX A;  4MWL A;  2QWD A;  4XMI A;  1Z4Y A;  4QN3 A;  4X47 A;  4KS5 A;  4NN9 A;  2QWG A;  2RKC A;  2VW1 A;  3TIB A;  4YZ1 A;  4XJQ A;  2YA8 A;  2XZJ A;  5JYY A;  4YZ3 A;  4H53 A;  1MS4 A;  4NC5 A;  3SLI A;  4KS1 A;  1NCC N;  3SAN A;  1MWE A;  1MS3 A;  1MS9 A;  4MWV A;  4WEF A;  4XJZ A;  5HUK A;  4XJW A;  1V3D A;  4X49 A;  4WA5 A;  1INV A;  4D8S A;  1N1T A;  2AEP A;  3O9K A;  1Z4X A;  3CKZ A;  2YA4 A;  5HUN A;  1KIT A;  4GDJ A;  3PJQ A;  3NSS A;  3TIC A;  4XHX A;  2W5N A;  4MWJ A;  4HZW A;  4XJ9 A;  1INX A;  2FHR A;  4FVK A;  4YZ2 A;  2X9M A;  4CPY A;  1INH A;  1B9S A;  5HUG A;  2HTV A;  1L7H A;  1V0E A;  3SIL A;  1MS5 A;  4XOG A;  1SNT A;  3TI5 A;  1V3C A;  1B9V A;  4GEZ A; 
#chains in the Genus database with same CATH topology
 2ZB6 A;  2VVZ A;  2GVX A;  2W8B A;  3TI8 A;  3TI6 A;  4AHA A;  3P5B L;  5GX1 A;  4UF7 A;  3S8Z A;  4CPO A;  5M1Z A;  1Z4W A;  1V3B A;  5FNS A;  1IVB A;  2SIL A;  3VNH A;  5HX0 A;  4XE9 A;  1W0O A;  4FPK A;  4MWU A;  4PWZ A;  1N1S A;  4B7J A;  2CML A;  3B7E A;  2QWB A;  1NCD N;  4CPL A;  2IAU A;  3AMR A;  4GNA A;  1NSD A;  1S0J A;  4M4U A;  4QN4 A;  4D52 B;  4HZV A;  3S8V A;  1XOG A;  2A75 A;  4FP3 A;  1NNB A;  3SAL A;  5CGJ A;  4YW5 A;  4FPO B;  4GZT A;  2HTQ A;  5NN9 A;  4FOY A;  1S18 A;  1ZI0 A;  3K38 A;  1VCU A;  4GDI A;  4YW2 A;  2VW0 A;  4FPJ A;  1NSC A;  1POO A;  4FPF A;  2ZB5 A;  1NSB A;  4C1Y B;  4FQ4 A;  4MWR A;  2OJH A;  4D4U A;  1E1A A;  4CHB A;  1PJX A;  3WN7 A;  3I1C A;  2ZW9 A;  4L7B A;  2QWJ A;  3A71 A;  4K1J A;  2BAT A;  4MWW A;  3ADE A;  4HZZ A;  4MX0 A;  2F24 A;  4XIK A;  3D12 A;  2XCY A;  4B7N A;  1W20 A;  1V0Z A;  1NNC A;  1CRZ A;  4XIO A;  1A14 N;  1E8V A;  2F13 A;  1A4Q A;  2F25 A;  3WW9 A;  4HW6 A;  4UOU A;  1DIM A;  2F27 A;  4JML A;  1INF A;  2GVW A;  2SIM A;  1EUU A;  2YDP A;  4XJU A;  1N1Y A;  1EUS A;  2VK5 A;  2ZWA A;  2IAV A;  3CL0 A;  4GNB A;  3SOQ A;  1EUR A;  4CSD A;  4B7M A;  3O4P A;  2YA6 A;  2IAP A;  3T1E A;  3LI4 A;  4N1B A;  4FOV A;  3HLH A;  3V64 C;  4O5T A;  4Q6K A;  2DSO A;  4IFJ A;  1SLI A;  4XJA A;  1Z50 A;  1U6D X;  4D52 A;  4GZS A;  4A0P A;  3A72 A;  2YA7 A;  1H6L A;  4FPG A;  1INY A;  1V2I A;  1IVF A;  2VAQ A;  1Z4Z A;  4ZY3 A;  1QLG A;  1NMC A;  2AGS A;  2H2N A;  6NN9 A;  2QWA A;  2JKB A;  2IAW A;  4XIL A;  4FOW A;  3K39 A;  3H72 A;  3S2K A;  3TIA A;  3D11 A;  4NCS A;  1USX A;  1L7G A;  4DGR A;  4XHB A;  3ALW A;  3JU4 A;  3FVZ A;  5H47 A;  1B9T A;  4AH4 A;  7NN9 A;  1F8C A;  4K1I A;  2F28 A;  4JF7 A;  4WA3 A;  1MR5 A;  2AEQ A;  1VCJ A;  4IMB A;  3GVK A;  3UC1 A;  4YZ4 A;  1WP5 A;  3SRG A;  3SOV A;  1W8N A;  4WEG A;  4XJR A;  4XMA A;  2QWH A;  4MC7 A;  1V0F A;  1L7F A;  3K36 A;  2VSK A;  1OFZ A;  2VK6 A;  2C4L A;  1NCA N;  2GHS A;  3KYA A;  1S1D A;  4IYG A;  2SLI A;  4K1H A;  4AGI A;  1NMA N;  1NPE A;  3NO0 A;  3GVJ A;  4GZX A;  3H73 A;  1XOE A;  5EO8 A;  2DYH A;  3ZGC A;  1N6F A;  1RWL A;  1IUC A;  2V91 A;  3H6J A;  4GN8 A;  2IAS A;  4DG6 A;  2W20 A;  4KS4 A;  1CVM A;  1E8T A;  3BEQ A;  2XZK A;  4J9T A;  2W38 A;  4G3N A;  4FPL A;  4WA4 A;  4QN7 A;  3W09 A;  2FP9 A;  1N6E A;  1NN2 A;  4MJU A;  2VK7 A;  1NCB N;  1N6D A;  3FW0 A;  4GZQ A;  2FPB A;  2POO A;  1W1X A;  1MS0 A;  4FPH A;  1IVD A;  5FNR A;  3DAS A;  2VPJ A;  2H2U A;  4ZLR A;  3CL2 A;  3S94 A;  1WCQ A;  1E8U A;  1MS8 A;  3G4H A;  3WWA A;  4YW4 A;  5F9T A;  2FP8 A;  1NNA A;  4CPZ A;  4FPE A;  4QN5 A;  4HZY A;  5EO7 A;  1SO7 A;  2P4O A;  2B8H A;  3B69 A;  4M3M A;  3INB A;  4ZGC A;  5D9D A;  1CQ1 A;  2QWE A;  4GZO A;  2HT5 A;  2W5O A;  4HHQ A;  4KS3 A;  3OPZ A;  4FPC A;  1F8B A;  1MZ5 A;  2YA5 A;  1IVC A;  4K1K A;  2VW2 A;  4HZX A;  1MZ6 A;  1USR A;  4YW3 A;  4GNC A;  4CPN A;  2F26 A;  1W21 A;  4QN6 A;  2FLU X;  4X6K A;  1Z4V A;  2AH2 A;  4MWQ A;  3V1S A;  2F11 A;  1RWI A;  4GJT A;  4K3Y A;  3CYE A;  4FP2 A;  3K3A A;  4ASC A;  3IAX A;  1S0I A;  3V65 B;  2QE8 A;  2VWD A;  3NN9 A;  2QWK A;  2HTR A;  3H71 A;  4FJ6 A;  3G4E A;  1X2J A;  2Z32 A;  2GVV A;  4FPY A;  4SLI A;  1BJI A;  1SUU A;  2IVZ A;  2BZD A;  2HT7 A;  3DR2 A;  4C1Y A;  2HU0 A;  3II7 A;  2HTU A;  4IFL X;  3KGG A;  4XYX A;  4MJV A;  4B7Q A;  4M4V A;  4GB1 A;  2F0Z A;  3ZGD A;  2HT8 A;  1N7D A;  5GX5 A;  1C5K A;  1IVE A;  3AMS A;  2IAT A;  4YY8 A;  2QWI A;  3TI3 A;  1WCS A;  1C9U A;  4X4A A;  2XZI A;  1ZGK A;  4M4N A;  2BF6 A;  1MS1 A;  4FZH A;  2XN4 A;  2ISM A;  2HTY A;  4MWY A;  2BER A;  2VSM A;  4KS2 A;  4XJ8 A;  2IAR A;  1F8E A;  4IQK A;  4MZA A;  2QWC A;  3O9J A;  1K32 A;  4GEZ A;  5GX2 A;  1INW A;  4BBW A;  4QNP A;  5GTQ A;  5B2D A;  4GZP A;  2F29 A;  1DIL A;  2C4A A;  1A4G A;  1IJQ A;  2HTW A;  4I00 A;  4D52 C;  2IAQ A;  4FOQ A;  1Q7F A;  2WOZ A;  5B2C A;  2DG0 A;  1V04 A;  1ING A;  1W0P A;  2F12 A;  1EUT A;  4HHO A;  3BYC A;  2F10 A;  3GVL A;  5FNQ A;  2HU4 A;  3TI4 A;  5FNU A;  2HQS A;  4B7R A;  5GX4 A;  1IVG A;  3U0S A;  4MWX A;  4HIZ A;  1SLL A;  1W8O A;  4H52 A;  4MZE A;  1V3E A;  5FZN A;  4GZW A;  4YW1 A;  1NMB N;  4IFN X;  4Q1U A;  2QWF A;  5HUM A;  2YDT A;  4O5S A;  2G8S A;  3A9H A;  3HLI A;  4YZ5 A;  4CPM A;  2W8B B;  5FZJ A;  3K37 A;  1F8D A;  2IAO A;  3ALX A;  4MWL A;  2QWD A;  4XMI A;  3Q6T A;  1Z4Y A;  4QN3 A;  4X47 A;  5FWW A;  2ZZK A;  5F72 C;  4KS5 A;  3Q6K A;  4NN9 A;  2QWG A;  2RKC A;  2VW1 A;  3TIB A;  4YZ1 A;  4XJQ A;  2YA8 A;  5FNT A;  3HRP A;  2XZJ A;  5JYY A;  3SOB B;  4YZ3 A;  1QBI A;  4H53 A;  2DG1 A;  1MS4 A;  4NC5 A;  4GN9 A;  3SLI A;  2FPC A;  4KS1 A;  1NCC N;  2GVU A;  1IUB A;  5D9C A;  4AGT A;  3SAN A;  1MWE A;  1MS3 A;  1MS9 A;  4MWV A;  4WEF A;  1CRU A;  4XJZ A;  2IAX A;  5HUK A;  4XJW A;  1V3D A;  4X49 A;  4WA5 A;  3Q6P A;  1INV A;  4D8S A;  1N1T A;  3LI5 A;  2AEP A;  3L6V A;  3O9K A;  4IN4 A;  3TC9 A;  3LI3 A;  1Z4X A;  4L7C A;  3CKZ A;  3A9G A;  2YA4 A;  5HUN A;  1KIT A;  5D9B A;  4GDJ A;  3VNG A;  3PJQ A;  4R40 A;  3NSS A;  3TIC A;  4XHX A;  2W5N A;  4MWJ A;  4HZW A;  4XJ9 A;  1INX A;  4CH9 A;  2FHR A;  4FVK A;  4YZ2 A;  1X2R A;  2X9M A;  3E5Z A;  4CPY A;  3SRE A;  1INH A;  1B9S A;  5HUG A;  2HTV A;  1L7H A;  1V0E A;  3SIL A;  5EX7 A;  3WDZ A;  1MS5 A;  4XOG A;  5GX3 A;  1SNT A;  3TI5 A;  4GN7 A;  4XMB A;  1V3C A;  1B9V A;  1N1V A;  4L7D A; 
#chains in the Genus database with same CATH homology
 2ZB6 A;  2VVZ A;  3TI8 A;  3TI6 A;  4UF7 A;  4CPO A;  5M1Z A;  1Z4W A;  1V3B A;  5HX0 A;  1IVB A;  2SIL A;  4XE9 A;  1W0O A;  4FPK A;  4MWU A;  1N1S A;  4B7J A;  2CML A;  3B7E A;  2QWB A;  1NCD N;  4CPL A;  1N1V A;  1NSD A;  1S0J A;  4M4U A;  4QN4 A;  4HZV A;  1XOG A;  2A75 A;  4FP3 A;  1NNB A;  3SAL A;  4YW5 A;  4FPO B;  4GZT A;  2HTQ A;  5NN9 A;  4FOY A;  1S18 A;  3K38 A;  1VCU A;  4GDI A;  4YW2 A;  2VW0 A;  4FPJ A;  1NSC A;  4FPF A;  2ZB5 A;  1NSB A;  4FQ4 A;  4MWR A;  2QWJ A;  3A71 A;  4K1J A;  2BAT A;  4MWW A;  4HZZ A;  4MX0 A;  2F24 A;  4XIK A;  3D12 A;  2XCY A;  4B7N A;  1W20 A;  1V0Z A;  1NNC A;  4XIO A;  1A14 N;  1E8V A;  2F13 A;  1A4Q A;  2F25 A;  1DIM A;  2F27 A;  1INF A;  2SIM A;  1EUU A;  2YDP A;  4XJU A;  1N1Y A;  1EUS A;  2VK5 A;  3CL0 A;  1EUR A;  4B7M A;  2YA6 A;  3T1E A;  4FOV A;  4Q6K A;  1SLI A;  4XJA A;  1Z50 A;  4GZS A;  3A72 A;  2YA7 A;  4FPG A;  1INY A;  1V2I A;  1IVF A;  1Z4Z A;  1NMC A;  2AGS A;  2H2N A;  6NN9 A;  2QWA A;  2JKB A;  4XIL A;  4FOW A;  3K39 A;  3H72 A;  3TIA A;  3D11 A;  4NCS A;  1USX A;  1L7G A;  4DGR A;  4XHB A;  3ALW A;  3JU4 A;  1B9T A;  7NN9 A;  1F8C A;  4K1I A;  2F28 A;  4JF7 A;  4WA3 A;  1MR5 A;  2AEQ A;  1VCJ A;  3GVK A;  4YZ4 A;  1W8N A;  4WEG A;  4XJR A;  4XMA A;  2QWH A;  4MC7 A;  1V0F A;  1L7F A;  3K36 A;  2VSK A;  2VK6 A;  2C4L A;  1NCA N;  1S1D A;  2SLI A;  4K1H A;  1NMA N;  3GVJ A;  4GZX A;  3H73 A;  1XOE A;  3H6J A;  2W20 A;  4KS4 A;  1E8T A;  3BEQ A;  2XZK A;  4J9T A;  2W38 A;  4FPL A;  4WA4 A;  4QN7 A;  3W09 A;  1NN2 A;  4MJU A;  2VK7 A;  1NCB N;  4GZQ A;  1W1X A;  1MS0 A;  4FPH A;  1IVD A;  2H2U A;  3CL2 A;  1WCQ A;  1E8U A;  1MS8 A;  4YW4 A;  5F9T A;  1NNA A;  4CPZ A;  4FPE A;  4QN5 A;  4HZY A;  1SO7 A;  3B69 A;  2B8H A;  4M3M A;  3INB A;  2QWE A;  4GZO A;  2HT5 A;  2W5O A;  4KS3 A;  3OPZ A;  4FPC A;  1F8B A;  1MZ5 A;  2YA5 A;  1IVC A;  4K1K A;  2VW2 A;  4HZX A;  1MZ6 A;  1USR A;  4YW3 A;  4CPN A;  2F26 A;  1W21 A;  4QN6 A;  4X6K A;  1Z4V A;  2AH2 A;  4MWQ A;  2F11 A;  4GJT A;  4K3Y A;  3CYE A;  4FP2 A;  3K3A A;  1S0I A;  2VWD A;  3NN9 A;  2QWK A;  2HTR A;  3H71 A;  4FJ6 A;  4FPY A;  4SLI A;  1BJI A;  2BZD A;  2HT7 A;  2HU0 A;  2HTU A;  4XYX A;  4MJV A;  4B7Q A;  4M4V A;  4GB1 A;  2F0Z A;  2HT8 A;  1IVE A;  2QWI A;  3TI3 A;  1WCS A;  4X4A A;  2XZI A;  4M4N A;  2BF6 A;  1MS1 A;  4FZH A;  2HTY A;  4MWY A;  2BER A;  2VSM A;  4KS2 A;  4XJ8 A;  1F8E A;  4MZA A;  2QWC A;  3O9J A;  1INW A;  4BBW A;  4QNP A;  5B2D A;  4GZP A;  2F29 A;  1DIL A;  2C4A A;  1A4G A;  2HTW A;  4I00 A;  4FOQ A;  5B2C A;  1ING A;  1W0P A;  2F12 A;  1EUT A;  2F10 A;  3GVL A;  2HU4 A;  3TI4 A;  4B7R A;  1IVG A;  4MWX A;  4HIZ A;  1SLL A;  1W8O A;  4H52 A;  4MZE A;  1V3E A;  4GZW A;  4YW1 A;  1NMB N;  2QWF A;  5HUM A;  2YDT A;  4YZ5 A;  4CPM A;  3K37 A;  1F8D A;  3ALX A;  4MWL A;  2QWD A;  4XMI A;  1Z4Y A;  4QN3 A;  4X47 A;  4KS5 A;  4NN9 A;  2QWG A;  2RKC A;  2VW1 A;  3TIB A;  4YZ1 A;  4XJQ A;  2YA8 A;  2XZJ A;  5JYY A;  4YZ3 A;  4H53 A;  1MS4 A;  4NC5 A;  3SLI A;  4KS1 A;  1NCC N;  3SAN A;  1MWE A;  1MS3 A;  1MS9 A;  4MWV A;  4WEF A;  4XJZ A;  5HUK A;  4XJW A;  1V3D A;  4X49 A;  4WA5 A;  1INV A;  4D8S A;  1N1T A;  2AEP A;  3O9K A;  1Z4X A;  3CKZ A;  2YA4 A;  5HUN A;  1KIT A;  4GDJ A;  3PJQ A;  3NSS A;  3TIC A;  4XHX A;  2W5N A;  4MWJ A;  4HZW A;  4XJ9 A;  1INX A;  2FHR A;  4FVK A;  4YZ2 A;  2X9M A;  4CPY A;  1INH A;  1B9S A;  5HUG A;  2HTV A;  1L7H A;  1V0E A;  3SIL A;  1MS5 A;  4XOG A;  1SNT A;  3TI5 A;  1V3C A;  1B9V A;  4GEZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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