4GDXA

Crystal structure of human gamma-glutamyl transpeptidase--glutamate complex
Total Genus 108
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
108
sequence length
342
structure length
342
Chain Sequence
PDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDAVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Gamma-glutamyltranspeptidase 1 heavy chain
publication title Novel Insights into Eukaryotic gamma-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Hydrolase
total genus 108
structure length 342
sequence length 342
ec nomenclature ec 2.3.2.2: Gamma-glutamyltransferase.
pdb deposition date 2012-08-01
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.246.130 Mainly Alpha Orthogonal Bundle Serum Albumin; Chain A, Domain 1 Serum Albumin; Chain A, Domain 1 4gdxA02
4ZC6A 2V36A 2E0YA 3WHQA 4GDXA 5BPKA 4GG2A 2E0XA 2DG5A 3A75A 3FNMA 2DBUA 2DBWA 4OTUA 5B5TA 3WHRA 4ZCGA 4ZBKA 4Z9OA 2NQOA 3WHSA 2QMCA 2Z8JA 2QM6A 2Z8IA 4OTTA 2DBXA 2Z8KA
chains in the Genus database with same CATH superfamily
1N5UA 4K71A 4WA6B 5FUOA 1HK1A 3NMUA 5DBYA 2KWFA 3MHSB 1KW2A 2XVQA 4PO0A 2BXIA 2BXCA 2DYOA 2E0XA 3MHHB 4FK5B 2EFEA 4LUHA 4HGMB 4TQ1A 3UIVA 3GQUA 3SIUB 1HK4A 3FWCC 4ZBQA 2BXLA 2DYMA 1E7IA 3B9LA 2XW0A 1E7HA 2BX8A 4LA0A 1UORA 1LNSA 4G04A 2LXTA 3GA9L 2EFCA 5GHKA 4S1YA 4L9KA 5GINA 4F5UA 3CX9A 5IIHA 5IIUA 4LB2A 4JK4A 2BXAA 1BM0A 4FJCB 1LOTA 3SQJA 1MIVA 3ECPA 1E7FA 1HK5A 3LU8A 5IJ5A 2Z8KA 2I30A 4N0UD 4M70B 3LU7A 5BPKA 1SB0A 2DG5A 4GG2A 3H3AA 4ZUXV 1E7AA 3SIVB 4MBEC 4FIPB 2XSIA 2BXKA 4I9OA 3A75A 4N0FD 1O9XA 3FWBC 2LOQA 3JRYA 2K0NA 4OTUA 5IJEA 2BXFA 3A73A 3G9KD 3B9MA 5ID7A 2XVVA 4NAWB 1MA9A 2OT3A 4K2CA 5IIXA 1MUHA 2BXEA 2XVUA 2NQOA 4E99A 1E78A 5IFOA 2KBZA 4GDKB 2QHBA 2VUEA 3NVIA 2DBXA 5GIOA 1H5WA 1GNIA 2OZBB 3V09A 1E7GA 3H37A 4OT2A 4G01A 4N3ZA 2V36A 5IJFA 2E0YA 4GDXA 2GUTA 4D7XA 1J7EA 3LU6A 3V08A 3V03A 3W1SA 4F5VA 1H9ZA 1VZSA 3NVKA 2BXHA 1E7EA 3FNMA 4LB9A 5ID9A 2XVWA 2BXNA 3KJLA 2JUHA 3WHRA 1MUSA 1JNBA 4IW1A 1BJ5A 4ZBKA 1KDXA 4DHXB 4OR0A 1J78A 1TXUA 4L8UA 2QMCA 4LUFA 4DM0A 1HA2A 2QM6A 2Z8IA 2XMOA 3JQZA 3NVMA 4J2VA 4HGKA 1VFIA 4Z69A 3PLAA 2LXSA 2NNWA 2YDFA 3BPJA 2LQHA 2ROHA 1FOUA 3KIKA 5DQFA 4ZC6A 4C31B 4F5TA 3WHQA 1BKEA 2EFHA 3ICXA 5D7GA 2BXMA 1E7CA 2BXBA 1IJGA 2BXPA 1TF0A 2BXDA 2VDBA 3M99C 4IW2A 2XW1A 4L9QA 4ZBRA 4TQ0A 4G03A 2AGHB 3GQXA 5HOZA 4BY9C 1MIYA 2DBUA 2DBWA 2AJEA 2EFDA 5B5TA 2BXOA 4ZCGA 1HK2A 4Z9OA 1HK3A 1E7BA 4W4UB 4GDLB 4BKEA 3VQIA 1AO6A 1MIWA 2VUFA 2BXQA 4F5SA 3WHSA 5GIPA 1KXPD 1MM8A 2Z8JA 1NT2B 2CKXA 4OTTA 4EMXA 2BXGA 2LQIA 3TDLA 2I2ZA 1GNJA
chains in the Genus database with same CATH topology
1N5UA 4K71A 4WA6B 5FUOA 1HK1A 3NMUA 5DBYA 3MHSB 1KW2A 2XVQA 4PO0A 2BXIA 2BXCA 2DYOA 2E0XA 3MHHB 4FK5B 2EFEA 4LUHA 4HGMB 4TQ1A 3UIVA 3GQUA 3SIUB 1HK4A 3FWCC 4ZBQA 2BXLA 2DYMA 1E7IA 3B9LA 2XW0A 1E7HA 2BX8A 4LA0A 1UORA 1LNSA 4G04A 3GA9L 2EFCA 5GHKA 4S1YA 4L9KA 5GINA 4F5UA 3CX9A 5IIHA 5IIUA 4LB2A 4JK4A 2BXAA 1BM0A 4FJCB 1LOTA 3SQJA 1MIVA 1E7FA 1HK5A 3LU8A 5IJ5A 2Z8KA 2I30A 4N0UD 4M70B 3LU7A 5BPKA 4GG2A 2DG5A 3H3AA 4ZUXV 1E7AA 3SIVB 4MBEC 4FIPB 2XSIA 2BXKA 3A75A 4N0FD 1O9XA 3FWBC 2LOQA 3JRYA 4OTUA 5IJEA 2BXFA 3A73A 3G9KD 3B9MA 5ID7A 2XVVA 4NAWB 1MA9A 2OT3A 4K2CA 5IIXA 2BXEA 2XVUA 2NQOA 4E99A 1E78A 5IFOA 2KBZA 4GDKB 2QHBA 2VUEA 3NVIA 2DBXA 5GIOA 1H5WA 1GNIA 2OZBB 3V09A 1E7GA 3H37A 4OT2A 4G01A 4N3ZA 2V36A 5IJFA 2E0YA 4GDXA 1J7EA 3LU6A 3V08A 3V03A 3W1SA 4F5VA 1H9ZA 1VZSA 3NVKA 2BXHA 1E7EA 3FNMA 4LB9A 5ID9A 2XVWA 2BXNA 3KJLA 2JUHA 3WHRA 1JNBA 4IW1A 1BJ5A 4ZBKA 4DHXB 4OR0A 1J78A 1TXUA 4L8UA 2QMCA 4LUFA 1HA2A 2QM6A 2Z8IA 2XMOA 3JQZA 3NVMA 4J2VA 4HGKA 1VFIA 4Z69A 3PLAA 2YDFA 2NNWA 2ROHA 1FOUA 3KIKA 5DQFA 4ZC6A 4C31B 4F5TA 3WHQA 1BKEA 2EFHA 3ICXA 5D7GA 2BXMA 1E7CA 2BXBA 1IJGA 2BXPA 1TF0A 2BXDA 2VDBA 3M99C 4IW2A 2XW1A 4L9QA 4ZBRA 4TQ0A 4G03A 3GQXA 5HOZA 4BY9C 1MIYA 2DBUA 2DBWA 2AJEA 2EFDA 5B5TA 2BXOA 4ZCGA 1HK2A 4Z9OA 1HK3A 1E7BA 4W4UB 4GDLB 4BKEA 3VQIA 1AO6A 1MIWA 2VUFA 2BXQA 4F5SA 3WHSA 5GIPA 1KXPD 2Z8JA 1NT2B 2CKXA 4OTTA 4EMXA 2BXGA 3TDLA 2I2ZA 1GNJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZC6 A;  2V36 A;  2E0Y A;  3WHQ A;  4GDX A;  5BPK A;  4GG2 A;  2E0X A;  2DG5 A;  3A75 A;  3FNM A;  2DBU A;  2DBW A;  4OTU A;  5B5T A;  3WHR A;  4ZCG A;  4ZBK A;  4Z9O A;  2NQO A;  3WHS A;  2QMC A;  2Z8J A;  2QM6 A;  2Z8I A;  4OTT A;  2DBX A;  2Z8K A; 
#chains in the Genus database with same CATH topology
 1N5U A;  4K71 A;  4WA6 B;  5FUO A;  1HK1 A;  3NMU A;  5DBY A;  2KWF A;  3MHS B;  1KW2 A;  2XVQ A;  4PO0 A;  2BXI A;  2BXC A;  2DYO A;  2E0X A;  3MHH B;  4FK5 B;  2EFE A;  4LUH A;  4HGM B;  4TQ1 A;  3UIV A;  3GQU A;  3SIU B;  1HK4 A;  3FWC C;  4ZBQ A;  2BXL A;  2DYM A;  1E7I A;  3B9L A;  2XW0 A;  1E7H A;  2BX8 A;  4LA0 A;  1UOR A;  1LNS A;  4G04 A;  2LXT A;  3GA9 L;  2EFC A;  5GHK A;  4S1Y A;  4L9K A;  5GIN A;  4F5U A;  3CX9 A;  5IIH A;  5IIU A;  4LB2 A;  4JK4 A;  2BXA A;  1BM0 A;  4FJC B;  1LOT A;  3SQJ A;  1MIV A;  3ECP A;  1E7F A;  1HK5 A;  3LU8 A;  5IJ5 A;  2Z8K A;  2I30 A;  4N0U D;  4M70 B;  3LU7 A;  5BPK A;  1SB0 A;  2DG5 A;  4GG2 A;  3H3A A;  4ZUX V;  1E7A A;  3SIV B;  4MBE C;  4FIP B;  2XSI A;  2BXK A;  4I9O A;  3A75 A;  4N0F D;  1O9X A;  3FWB C;  2LOQ A;  3JRY A;  2K0N A;  4OTU A;  5IJE A;  2BXF A;  3A73 A;  3G9K D;  3B9M A;  5ID7 A;  2XVV A;  4NAW B;  1MA9 A;  2OT3 A;  4K2C A;  5IIX A;  1MUH A;  2BXE A;  2XVU A;  2NQO A;  4E99 A;  1E78 A;  5IFO A;  2KBZ A;  4GDK B;  2QHB A;  2VUE A;  3NVI A;  2DBX A;  5GIO A;  1H5W A;  1GNI A;  2OZB B;  3V09 A;  1E7G A;  3H37 A;  4OT2 A;  4G01 A;  4N3Z A;  2V36 A;  5IJF A;  2E0Y A;  4GDX A;  2GUT A;  4D7X A;  1J7E A;  3LU6 A;  3V08 A;  3V03 A;  3W1S A;  4F5V A;  1H9Z A;  1VZS A;  3NVK A;  2BXH A;  1E7E A;  3FNM A;  4LB9 A;  5ID9 A;  2XVW A;  2BXN A;  3KJL A;  2JUH A;  3WHR A;  1MUS A;  1JNB A;  4IW1 A;  1BJ5 A;  4ZBK A;  1KDX A;  4DHX B;  4OR0 A;  1J78 A;  1TXU A;  4L8U A;  2QMC A;  4LUF A;  4DM0 A;  1HA2 A;  2QM6 A;  2Z8I A;  2XMO A;  3JQZ A;  3NVM A;  4J2V A;  4HGK A;  1VFI A;  4Z69 A;  3PLA A;  2LXS A;  2NNW A;  2YDF A;  3BPJ A;  2LQH A;  2ROH A;  1FOU A;  3KIK A;  5DQF A;  4ZC6 A;  4C31 B;  4F5T A;  3WHQ A;  1BKE A;  2EFH A;  3ICX A;  5D7G A;  2BXM A;  1E7C A;  2BXB A;  1IJG A;  2BXP A;  1TF0 A;  2BXD A;  2VDB A;  3M99 C;  4IW2 A;  2XW1 A;  4L9Q A;  4ZBR A;  4TQ0 A;  4G03 A;  2AGH B;  3GQX A;  5HOZ A;  4BY9 C;  1MIY A;  2DBU A;  2DBW A;  2AJE A;  2EFD A;  5B5T A;  2BXO A;  4ZCG A;  1HK2 A;  4Z9O A;  1HK3 A;  1E7B A;  4W4U B;  4GDL B;  4BKE A;  3VQI A;  1AO6 A;  1MIW A;  2VUF A;  2BXQ A;  4F5S A;  3WHS A;  5GIP A;  1KXP D;  1MM8 A;  2Z8J A;  1NT2 B;  2CKX A;  4OTT A;  4EMX A;  2BXG A;  2LQI A;  3TDL A;  2I2Z A;  1GNJ A; 
#chains in the Genus database with same CATH homology
 1N5U A;  4K71 A;  4WA6 B;  5FUO A;  1HK1 A;  3NMU A;  5DBY A;  3MHS B;  1KW2 A;  2XVQ A;  4PO0 A;  2BXI A;  2BXC A;  2DYO A;  2E0X A;  3MHH B;  4FK5 B;  2EFE A;  4LUH A;  4HGM B;  4TQ1 A;  3UIV A;  3GQU A;  3SIU B;  1HK4 A;  3FWC C;  4ZBQ A;  2BXL A;  2DYM A;  1E7I A;  3B9L A;  2XW0 A;  1E7H A;  2BX8 A;  4LA0 A;  1UOR A;  1LNS A;  4G04 A;  3GA9 L;  2EFC A;  5GHK A;  4S1Y A;  4L9K A;  5GIN A;  4F5U A;  3CX9 A;  5IIH A;  5IIU A;  4LB2 A;  4JK4 A;  2BXA A;  1BM0 A;  4FJC B;  1LOT A;  3SQJ A;  1MIV A;  1E7F A;  1HK5 A;  3LU8 A;  5IJ5 A;  2Z8K A;  2I30 A;  4N0U D;  4M70 B;  3LU7 A;  5BPK A;  4GG2 A;  2DG5 A;  3H3A A;  4ZUX V;  1E7A A;  3SIV B;  4MBE C;  4FIP B;  2XSI A;  2BXK A;  3A75 A;  4N0F D;  1O9X A;  3FWB C;  2LOQ A;  3JRY A;  4OTU A;  5IJE A;  2BXF A;  3A73 A;  3G9K D;  3B9M A;  5ID7 A;  2XVV A;  4NAW B;  1MA9 A;  2OT3 A;  4K2C A;  5IIX A;  2BXE A;  2XVU A;  2NQO A;  4E99 A;  1E78 A;  5IFO A;  2KBZ A;  4GDK B;  2QHB A;  2VUE A;  3NVI A;  2DBX A;  5GIO A;  1H5W A;  1GNI A;  2OZB B;  3V09 A;  1E7G A;  3H37 A;  4OT2 A;  4G01 A;  4N3Z A;  2V36 A;  5IJF A;  2E0Y A;  4GDX A;  1J7E A;  3LU6 A;  3V08 A;  3V03 A;  3W1S A;  4F5V A;  1H9Z A;  1VZS A;  3NVK A;  2BXH A;  1E7E A;  3FNM A;  4LB9 A;  5ID9 A;  2XVW A;  2BXN A;  3KJL A;  2JUH A;  3WHR A;  1JNB A;  4IW1 A;  1BJ5 A;  4ZBK A;  4DHX B;  4OR0 A;  1J78 A;  1TXU A;  4L8U A;  2QMC A;  4LUF A;  1HA2 A;  2QM6 A;  2Z8I A;  2XMO A;  3JQZ A;  3NVM A;  4J2V A;  4HGK A;  1VFI A;  4Z69 A;  3PLA A;  2YDF A;  2NNW A;  2ROH A;  1FOU A;  3KIK A;  5DQF A;  4ZC6 A;  4C31 B;  4F5T A;  3WHQ A;  1BKE A;  2EFH A;  3ICX A;  5D7G A;  2BXM A;  1E7C A;  2BXB A;  1IJG A;  2BXP A;  1TF0 A;  2BXD A;  2VDB A;  3M99 C;  4IW2 A;  2XW1 A;  4L9Q A;  4ZBR A;  4TQ0 A;  4G03 A;  3GQX A;  5HOZ A;  4BY9 C;  1MIY A;  2DBU A;  2DBW A;  2AJE A;  2EFD A;  5B5T A;  2BXO A;  4ZCG A;  1HK2 A;  4Z9O A;  1HK3 A;  1E7B A;  4W4U B;  4GDL B;  4BKE A;  3VQI A;  1AO6 A;  1MIW A;  2VUF A;  2BXQ A;  4F5S A;  3WHS A;  5GIP A;  1KXP D;  2Z8J A;  1NT2 B;  2CKX A;  4OTT A;  4EMX A;  2BXG A;  3TDL A;  2I2Z A;  1GNJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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