4GIQR

Crystal structure of mouse rank bound to rankl
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
164
structure length
164
Chain Sequence
CTQERHYEHLGRCCSRCEPGKYLSSKCTPTSDSVCLPCGPDEYLDTWNEEDKCLLHKVCDAGKALVAVDPGNHTAPRRCACTAGYHWNSDCECCRRNTECAPGFGAQHPLQLNKDTVCTPCLLGFFSDVFSSTDKCKPWTNCTLLGKLEAHQGTTESDVVCSSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding/protein binding
molecule keywords Tumor necrosis factor ligand superfamily member 11
publication title RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor.
pubmed doi rcsb
source organism Mus musculus
total genus 27
structure length 164
sequence length 164
ec nomenclature
pdb deposition date 2012-08-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
R PF00020 TNFR_c6 TNFR/NGFR cysteine-rich region
R PF18278 RANK_CRD_2 Receptor activator of the NF-KB cysteine-rich repeat domain 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4giqR02
2.10.50.10 Mainly Beta Ribbon Tumor Necrosis Factor Receptor, subunit A; domain 2 Tumor Necrosis Factor Receptor, subunit A, domain 2 4giqR01
3ME2R 5BNQR 3ALQR 4MXWR 4YN0A 2HEYR 4E4DR 5DMJA 4FHQA 4KGGC 4M4RA 1TNRR 3MBWA 1ZA3R 3U3SA 5L36B 4BK5A 3U3QA 3FL7A 3IJ2X 4I9XC 5CIRE 3U3TA 1FT4A 1D0GR 3BUKC 3QO4A 3ME4A 4OD2S 3URFZ 4RSUD 5IHLA 2X10A 1D4VA 3U3PA 3U3VA 4N90R 3K51B 3QD6R 3TJEF 3MHDD 4J6GC 1EXTA 4MSVB 1JMAB 2H9GR 1DU3A 4M4PA 2AW2B 3WVTA 3THMF 3MI8D 4BK4A 3QBQB 1NCFA 1SG1X 2HEVR 4KGQC 4GIQR 3X3FA 2UWIA
chains in the Genus database with same CATH superfamily
3ME2R 5BNQR 3ALQR 4MXWR 4YN0A 2HEYR 4E4DR 2E4YA 2E4WA 5DMJA 4FHQA 4KGGC 4M4RA 1TNRR 2E4VA 1ZA3R 3MBWA 3U3SA 5L36B 2E4XA 2E4UA 4BK5A 3U3QA 3FL7A 3IJ2X 4I9XC 5CIRE 3U3TA 1FT4A 1D0GR 3BUKC 3QO4A 3ME4A 4OD2S 3URFZ 4RSUD 5IHLA 2X10A 1D4VA 3U3PA 3U3VA 4N90R 3K51B 3QD6R 3TJEF 3MHDD 4J6GC 1EXTA 4MSVB 1JMAB 2H9GR 1DU3A 4M4PA 2AW2B 2QR6A 3WVTA 3THMF 3MI8D 4BK4A 3QBQB 1NCFA 1SG1X 2HEVR 4KGQC 4GIQR 3X3FA 2UWIA
chains in the Genus database with same CATH topology
3ME2R 5BNQR 3ALQR 4MXWR 4YN0A 2HEYR 4E4DR 5DMJA 4FHQA 4KGGC 4M4RA 1TNRR 3MBWA 1ZA3R 3U3SA 5L36B 4BK5A 3U3QA 3FL7A 3IJ2X 4I9XC 5CIRE 3U3TA 1FT4A 1D0GR 3BUKC 3QO4A 3ME4A 4OD2S 3URFZ 4RSUD 5IHLA 2X10A 1D4VA 3U3PA 3U3VA 4N90R 3K51B 3QD6R 3TJEF 3MHDD 4J6GC 1EXTA 4MSVB 1JMAB 2H9GR 1DU3A 4M4PA 2AW2B 3WVTA 3THMF 3MI8D 4BK4A 3QBQB 1NCFA 1SG1X 2HEVR 4KGQC 4GIQR 3X3FA 2UWIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ME2 R;  5BNQ R;  3ALQ R;  4MXW R;  4YN0 A;  2HEY R;  4E4D R;  5DMJ A;  4FHQ A;  4KGG C;  4M4R A;  1TNR R;  3MBW A;  1ZA3 R;  3U3S A;  5L36 B;  4BK5 A;  3U3Q A;  3FL7 A;  3IJ2 X;  4I9X C;  5CIR E;  3U3T A;  1FT4 A;  1D0G R;  3BUK C;  3QO4 A;  3ME4 A;  4OD2 S;  3URF Z;  4RSU D;  5IHL A;  2X10 A;  1D4V A;  3U3P A;  3U3V A;  4N90 R;  3K51 B;  3QD6 R;  3TJE F;  3MHD D;  4J6G C;  1EXT A;  4MSV B;  1JMA B;  2H9G R;  1DU3 A;  4M4P A;  2AW2 B;  3WVT A;  3THM F;  3MI8 D;  4BK4 A;  3QBQ B;  1NCF A;  1SG1 X;  2HEV R;  4KGQ C;  4GIQ R;  3X3F A;  2UWI A; 
#chains in the Genus database with same CATH topology
 3ME2 R;  5BNQ R;  3ALQ R;  4MXW R;  4YN0 A;  2HEY R;  4E4D R;  2E4Y A;  2E4W A;  5DMJ A;  4FHQ A;  4KGG C;  4M4R A;  1TNR R;  2E4V A;  1ZA3 R;  3MBW A;  3U3S A;  5L36 B;  2E4X A;  2E4U A;  4BK5 A;  3U3Q A;  3FL7 A;  3IJ2 X;  4I9X C;  5CIR E;  3U3T A;  1FT4 A;  1D0G R;  3BUK C;  3QO4 A;  3ME4 A;  4OD2 S;  3URF Z;  4RSU D;  5IHL A;  2X10 A;  1D4V A;  3U3P A;  3U3V A;  4N90 R;  3K51 B;  3QD6 R;  3TJE F;  3MHD D;  4J6G C;  1EXT A;  4MSV B;  1JMA B;  2H9G R;  1DU3 A;  4M4P A;  2AW2 B;  2QR6 A;  3WVT A;  3THM F;  3MI8 D;  4BK4 A;  3QBQ B;  1NCF A;  1SG1 X;  2HEV R;  4KGQ C;  4GIQ R;  3X3F A;  2UWI A; 
#chains in the Genus database with same CATH homology
 3ME2 R;  5BNQ R;  3ALQ R;  4MXW R;  4YN0 A;  2HEY R;  4E4D R;  5DMJ A;  4FHQ A;  4KGG C;  4M4R A;  1TNR R;  3MBW A;  1ZA3 R;  3U3S A;  5L36 B;  4BK5 A;  3U3Q A;  3FL7 A;  3IJ2 X;  4I9X C;  5CIR E;  3U3T A;  1FT4 A;  1D0G R;  3BUK C;  3QO4 A;  3ME4 A;  4OD2 S;  3URF Z;  4RSU D;  5IHL A;  2X10 A;  1D4V A;  3U3P A;  3U3V A;  4N90 R;  3K51 B;  3QD6 R;  3TJE F;  3MHD D;  4J6G C;  1EXT A;  4MSV B;  1JMA B;  2H9G R;  1DU3 A;  4M4P A;  2AW2 B;  3WVT A;  3THM F;  3MI8 D;  4BK4 A;  3QBQ B;  1NCF A;  1SG1 X;  2HEV R;  4KGQ C;  4GIQ R;  3X3F A;  2UWI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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