4GIZC

Crystal structure of full-length human papillomavirus oncoprotein e6 in complex with lxxll peptide of ubiquitin ligase e6ap at 2.55 a resolution
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
142
structure length
142
Chain Sequence
FQDPQERPRKLPQLCTELQTTIHDIILECVYCKQQLLRREVYDFARRDLCIVYRDGNPYAVCDKCLKFYSKISEYRHYSYSLYGTTLEQQYNKPLSDLLIRCINCQKPLSPEEKQRHLDKKQRFHNIRGRWTGRCMSCSRSS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Viral protein
molecule keywords Maltose-binding periplasmic protein, UBIQUITIN LIGASE EA6P:
publication title Structural basis for hijacking of cellular LxxLL motifs by papillomavirus E6 oncoproteins.
pubmed doi rcsb
source organism Escherichia coli
total genus 45
structure length 142
sequence length 142
chains with identical sequence D
ec nomenclature
pdb deposition date 2012-08-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00518 E6 Early Protein (E6)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.240.40 Alpha Beta 2-Layer Sandwich CRO Repressor CRO Repressor 4gizC01
3.30.240.40 Alpha Beta 2-Layer Sandwich CRO Repressor CRO Repressor 4gizC02
2M3LA 2FK4A 4GIZC 2LJYA 4XR8F 2LJXA 2LJZA
chains in the Genus database with same CATH superfamily
5CROA 3ORCA 2LJXA 2FK4A 1COPD 4GIZC 4XR8F 6CROA 1ORCA 2ECSA 1WU7A 2A63A 1D1LA 2LJZA 1D1MA 2M3LA 2OVGA 2LJYA 2ORCA 3C6FA 2CW1A
chains in the Genus database with same CATH topology
5CROA 3ORCA 2LJXA 2FK4A 1COPD 4GIZC 4XR8F 6CROA 1ORCA 2ECSA 1WU7A 2A63A 1D1LA 2LJZA 1D1MA 2M3LA 2OVGA 2LJYA 2ORCA 2CW1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2M3L A;  2FK4 A;  4GIZ C;  2LJY A;  4XR8 F;  2LJX A;  2LJZ A; 
#chains in the Genus database with same CATH topology
 5CRO A;  3ORC A;  2LJX A;  2FK4 A;  1COP D;  4GIZ C;  4XR8 F;  6CRO A;  1ORC A;  2ECS A;  1WU7 A;  2A63 A;  1D1L A;  2LJZ A;  1D1M A;  2M3L A;  2OVG A;  2LJY A;  2ORC A;  3C6F A;  2CW1 A; 
#chains in the Genus database with same CATH homology
 5CRO A;  3ORC A;  2LJX A;  2FK4 A;  1COP D;  4GIZ C;  4XR8 F;  6CRO A;  1ORC A;  2ECS A;  1WU7 A;  2A63 A;  1D1L A;  2LJZ A;  1D1M A;  2M3L A;  2OVG A;  2LJY A;  2ORC A;  2CW1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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